CN1843492A

CN1843492A - Traditional Chinese medicine preparation for treating mammary gland hyperplasia

Info

Publication number: CN1843492A
Application number: CNA2006100418183A
Authority: CN
Inventors: 徐樊; 徐朝霞
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-02-17
Filing date: 2006-02-17
Publication date: 2006-10-11
Anticipated expiration: 2026-02-17
Also published as: CN100374147C

Abstract

Disclosed is a Chinese medicinal preparation for treating mammary gland hyperplasia and tumor, which is prepared from the following raw materials: drynaria, pangolin scales, rhizoma Gastrodiae, duchesnea, pseudo-ginseng powder, prunella spike, curcuma root, ganoderma lucidum, astragalus root, Chinese angelica root, root of herbaceous peony, dandelion, oyster, cactus, myrrh, cow-bezoar and barbat skullcap.

Description

The Chinese medicine preparation of treatment cyclomastopathy and tumor

Technical field

The invention belongs to a kind of medicinal preparation, the particularly a kind of treatment cyclomastopathy of raw material of Chinese medicine preparation and Chinese medicine preparation of tumor of adopting.

Background technology

Mastopathy is one of principal disease of harm WomanHealth, and the lighter's distending pain of the breast is not healed for many years, and weight person suffers from the long-term pain of cyclomastopathy.Even developing into breast tumor, the very reluctantly excision breast of having to has a strong impact on women's physical and mental health.At present the Western medicine of clinical treatment cyclomastopathy mainly is the tamoxifen preparation, but its side effect makes patient's worry Zhong Zhong.Be better than above-mentioned Western medicine although list the RUKANG PIAN therapeutic effect of China's drug standard in, still curative effect is on the low side, and does not have too obvious effects for mammary neoplasms.

Summary of the invention

The object of the invention provides a kind of to cyclomastopathy and the medicative pure Chinese medicinal preparation of breast tumor.

The traditional Chinese medical science is thought: the cyclomastopathy main reason is that irritability is smouldered, qi depression to blood stasis.Dispersing the stagnated live-QI to relieve the stagnation of QI, regulating QI to relieve pain, promoting blood circulation and breaking stagnation, removing food stagnancy reduce phlegm so the present invention has mainly screened, the medicine of hard masses softening and resolving, air making-up and spleen enlivening comes prescription, to reach the purpose of treatment mastopathy.

Specifically, a kind of Chinese medicine preparation for the treatment of cyclomastopathy and tumor, it is to be made by following parts by weight of Chinese traditional medicine raw material:

Herba Pyrolae 25---35, Rhizoma Drynariae 25---35, Squama Manis 12---18,

Radix Semiaquilegiae 15---25, Herba Duchesneae Indicae 25---35, Radix Notoginseng powder 8---11

Rhizoma Amorphophalli 25---35, Spica Prunellae 17---22, RADIX CURCUMAE 12---18,

Ganoderma 12---18, Radix Astragali 25---35, Fructus Trichosanthis 25---35,

Folium Citri tangerinae 12---18, Radix Angelicae Sinensis 15---25, Radix Paeoniae Alba (parched) 12---18,

The bright juice 30---40 of Herba Taraxaci 25---35, Concha Ostreae 25---35, Radix et Caulis Opuntiae Dillenii,

Myrrha 8---10, Calculus Bovis 0.2---0.40, Herba Scutellariae Barbatae 15---25.

The preferential treatment cyclomastopathy of recommending of the present invention and the Chinese medicine preparation of tumor are to be made by following parts by weight of Chinese traditional medicine raw material:

Herba Pyrolae 30, Rhizoma Drynariae 30, Squama Manis 15, Radix Semiaquilegiae 20, Herba Duchesneae Indicae 30, Radix Notoginseng powder 10, Rhizoma Amorphophalli 30, Spica Prunellae 20, RADIX CURCUMAE 15, Ganoderma 15, the Radix Astragali 30, Fructus Trichosanthis 30, Folium Citri tangerinae 15, Radix Angelicae Sinensis 20, Radix Paeoniae Alba (parched) 15, Herba Taraxaci 30, Concha Ostreae 30, the bright juice 35 of Radix et Caulis Opuntiae Dillenii, Myrrha 9, Calculus Bovis 0.30, Herba Scutellariae Barbatae 20.

Each herbal medicine effect is as follows among the present invention: Herba Pyrolae---nourishing liver, invigorating kidney, and bone and muscle strengthening is mended the wind dehumidifying; Rhizoma Drynariae---the kidney invigorating tooth strengthening and pain stopping, the continuous muscle of invigorating blood circulation is cured the wound; Row is dense in Squama Manis---detumescence, the stimulating milk secretion of stimulating the menstrual flow; It Cai----heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, diuresis; Herba Scutellariae Barbatae---heat-clearing and toxic substances removing, inducing diuresis to remove edema; Herba Taraxaci---heat clearing away toxin expelling, liver heat removing and eyesight improving; Serpentis is cool---heat clearing away toxin expelling, eliminating stagnation repercussive; Radix Notoginseng---hemostasia and dissipation blood stasis, subduing swelling and relieving pain; Rhizoma Amorphophalli---dispersing swelling and dissipating binds, the toxin expelling pain relieving; The Spica Prunellae---eliminating stagnation of relieving inflammation or internal heat, removing heat from the liver to lower the high blood pressure; RADIX CURCUMAE---circulation of qi promoting blood stasis dispelling, the row that clears away heart-fire is strongly fragrant, cooling blood for hemostasis; Ganoderma---calm the nerves, be good for the stomach, relieving cough and asthma; The Radix Astragali---tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema; Fructus Trichosanthis---removing heat-phlegm, relieving epigastric distention and reducing the stagnation, carbuncle, loosening bowel to relieve constipation are treated in detumescence; Folium Citri tangerinae---drying dampness to eliminate phlegm, regulating qi-flowing for strengthening spleen; Radix Angelicae Sinensis---tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation; The Radix Paeoniae Alba (parched)---yin fluid astringing of enriching blood, easing the affected liver is antipruritic, the yin nourishing suppressing the hyperactive liver; Concha Ostreae---calm calming the nerves, the tonifying YIN YANG hyperactivity suppressing, restrain astringent or styptic treatment for spontaneous sweating, hard masses softening and resolving; Myrrha---promoting blood circulation and stopping pain, detumescence and promoting granulation; The Calculus Bovis---eliminating phlegm of having one's ideas straightened out, the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away toxin expelling; Bright juice--the mass dissipating and swelling eliminating of Radix et Caulis Opuntiae Dillenii.

Prescription of the present invention has that reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling, heat clearing away toxin expelling, eliminating stagnation repercussive, circulation of qi promoting eliminate the phlegm, the effect of regulating qi-flowing for strengthening spleen, not only for hyperplasia of mammary glands good therapeutic effect is arranged, and some breast tumor also has the obvious suppression effect.Preparation of the present invention proves nontoxic through acute and chronic toxicity test.The process inventor reaches 5 years patients' more than 200 clinical use, and proving effect is infallible, does not see the toxic and side effects reflection.

The specific embodiment

Embodiment 1: a kind of Chinese medicine preparation for the treatment of cyclomastopathy and tumor, and it is to be made by following parts by weight of Chinese traditional medicine raw material:

Herba Pyrolae 25, Rhizoma Drynariae 35, Squama Manis 12, Radix Semiaquilegiae 25, Herba Duchesneae Indicae 25, Radix Notoginseng powder 11, Rhizoma Amorphophalli 25, Spica Prunellae 22, RADIX CURCUMAE 12, Ganoderma 18, the Radix Astragali 25, Fructus Trichosanthis 35, Folium Citri tangerinae 12, Radix Angelicae Sinensis 25, Radix Paeoniae Alba (parched) 12, Herba Taraxaci 35, Concha Ostreae 25, the bright juice 40 of Radix et Caulis Opuntiae Dillenii, Myrrha 8, Calculus Bovis 0.40, Herba Scutellariae Barbatae 15.

Said medicine is crushed to the above fine powder of 100 orders behind all the other cleaning-dryings of the bright juice of Radix et Caulis Opuntiae Dillenii, adds and make the watered pill behind the Radix et Caulis Opuntiae Dillenii aquatic foods juice or honeyed pill gets final product.

Embodiment 2: a kind of Chinese medicine preparation for the treatment of cyclomastopathy and tumor, and it is to be made by following parts by weight of Chinese traditional medicine raw material:

Herba Pyrolae 35, Rhizoma Drynariae 25, Squama Manis 18, Radix Semiaquilegiae 15, Herba Duchesneae Indicae 35, Radix Notoginseng powder 8, Rhizoma Amorphophalli 35, Spica Prunellae 17, RADIX CURCUMAE 18, Ganoderma 12, the Radix Astragali 35, Fructus Trichosanthis 25, Folium Citri tangerinae 18, Radix Angelicae Sinensis 15, Radix Paeoniae Alba (parched) 18, Herba Taraxaci 25, Concha Ostreae 35, the bright juice 30 of Radix et Caulis Opuntiae Dillenii, Myrrha 10, Calculus Bovis 0.2, Herba Scutellariae Barbatae 25.

Said medicine is crushed to the above fine powder of 100 orders behind all the other cleaning-dryings except that the bright juice of Radix et Caulis Opuntiae Dillenii, continues to incapsulate after the drying behind the bright juice of adding Radix et Caulis Opuntiae Dillenii, get final product.

The present invention's 246 routine clinical treatment final reports

One, patient source: department of Chinese medicine outpatient service

Two, patient's ordinary circumstance: the patient is totally 246 people, is the women, and age distribution is 23 years old-52 years old.The course of disease the longest ten years, the shortest three months, wherein make a definite diagnosis cyclomastopathy patient 202 people, with breast tumor person 44 people.

Three, make a definite diagnosis method: be as the criterion with the imaging examination diagnosis.Tcm clinical practice performance mainly contains: lump in breast is touched a tender spot obviously, is upset, bitter taste red tongue, tongue are white.

Four, curative effect judging standard: " traditional Chinese medical science disease diagnoses and treatment standard " according to State Administration of Traditional Chinese Medicine's promulgation is divided into healing, produce effects, effective, invalid four ranks.

Cure: the imaging examination cyclomastopathy is eliminated fully, no clinical symptoms performance.

Produce effects: the imaging examination cyclomastopathy is most of to be eliminated, and the clinical symptoms performance alleviates obviously.

Effectively: the imaging examination cyclomastopathy is partly eliminated, and the clinical symptoms performance alleviates.

Invalid: the imaging examination cyclomastopathy does not change, and variation is not seen in the clinical symptoms performance.

Five, Therapeutic Method

Above-mentioned patient is divided into two groups at random, treatment group (taking medicine of the present invention) 206 people, matched group (taking RUKANG PIAN, the Ankang Taisho Pharmaceutical) 40 people.Two groups of patient ages, course of disease no significant difference have comparability.The treatment group is taken preparation 15g of the present invention every day, divides and takes for three times.Matched group is taken RUKANG PIAN 4-6 grain every day, takes at twice.Two groups are not all used the other treatment means.

Six, result's statistics is as following table

1,206 people are organized in treatment

Diagnosis	The example number	Cure number and ratio	Produce effects number and ratio	Significant figure and ratio	Invalid number and ratio
Diagnosis	The example number	Cure number and ratio	Produce effects number and ratio	Significant figure and ratio	Invalid number and ratio	Cyclomastopathy	172	131(76)	23(13)	18(11)	0(0)
Breast tumor	34	5(15)	17(50)	11(32)	1(29)	Cyclomastopathy	172	131(76)	23(13)	18(11)	0(0)

2, matched group 40 people

Diagnosis	The example number	Cure number and ratio	Produce effects number and ratio	Significant figure and ratio	Invalid number and ratio
Diagnosis	The example number	Cure number and ratio	Produce effects number and ratio	Significant figure and ratio	Invalid number and ratio	Cyclomastopathy	33	17(52)	5(15)	6(19))	5(15)
Breast tumor	7	0	0	2(29)	5(71)	Cyclomastopathy	33	17(52)	5(15)	6(19))	5(15)

3, the result relatively

Preparation of the present invention reaches 72% to the cure rate of cyclomastopathy, and total effective rate is 100%; The breast tumor cure rate is also had 15%, and total effective rate has reached 71%.And matched group has only 52% to the cure rate of cyclomastopathy, and total effective rate is 85%; Breast tumor there is not effect substantially.

The result shows that the treatment group obviously is better than matched group for cyclomastopathy and tumor treatment effect.

Seven, model case

1, Ms Zhang, 38 years old, suffered from cyclomastopathy 6 years, quilt is proved conclusively is breast tumor, hospital's suggestion excision left breast.I am reluctant that excision is with adopting preparation for treating of the present invention.Distending pain of the breast during menstruation, feeling of oppression over the chest and distention of hypochondrium, the bitter taste red tongue, tongue is white.Take that clinical symptoms disappears substantially after three months, make ultrasound diagnosis rear udder attachment tumor and obviously dwindle, continue to take 2 months rear udder attachment tumors and disappear.I am very satisfied.

2, Miss Qi 23 years old, suffered from cyclomastopathy 2 years.Lump in breast is touched a tender spot obviously during prescription on individual diagnosis, and menses are dark red clot, tongue with ecchymosis, and tongue is white, stringy and hesitant pulse.Take preparation of the present invention and promptly felt that lump in breast disappeared in 10 days, the oncontacting pain.Do to confirm that cyclomastopathy disappears after the ultrasound diagnosis.

3, Mrs Guo, 46 years old, suffered from cyclomastopathy 15 years, breast tenderness cuts in and out, and dysmenorrhea, menorrhagia often occur, never adheres to treatment.Take 3 weeks of preparation of the present invention and promptly feel to be emotionally stable, breast does not have obvious tenderness sense.Cyclomastopathy obviously reduces after doing ultrasound diagnosis.

Claims

1, a kind of Chinese medicine preparation for the treatment of cyclomastopathy and tumor is characterized in that being made by following parts by weight of Chinese traditional medicine raw material:

Herba Pyrolae 25---35, Rhizoma Drynariae 25---35, Squama Manis 12---18,

Radix Semiaquilegiae 1---2, Herba Duchesneae Indicae 25---35, Radix Notoginseng powder 8---11,

Rhizoma Amorphophalli 25---35, Spica Prunellae 17---22, RADIX CURCUMAE 12---18,

Ganoderma 12---18, Radix Astragali 25---35, Fructus Trichosanthis 25---35,

Myrrha 8---10, Calculus Bovis 0.2---0.40 Herba Scutellariae Barbatae 15---25.

2, the Chinese medicine preparation of treatment cyclomastopathy according to claim 1 and tumor is characterized in that being made by following parts by weight of Chinese traditional medicine raw material:

Herba Pyrolae 30, Rhizoma Drynariae 30, Squama Manis 15, Radix Semiaquilegiae 20, Serpentis 30, Radix Notoginseng powder 10, Rhizoma Amorphophalli 30, Spica Prunellae 20, RADIX CURCUMAE 15, Ganoderma 15, the Radix Astragali 30, Fructus Trichosanthis 30, Folium Citri tangerinae 15, Radix Angelicae Sinensis 20, Radix Paeoniae Alba (parched) 15, Herba Taraxaci 30, Concha Ostreae 30, the bright juice 35 of Radix et Caulis Opuntiae Dillenii, Myrrha 9, Calculus Bovis 0.30, Herba Scutellariae Barbatae 20.