CN1840065A - Dispersible tablet for eliminating inflammation and preparation method thereof - Google Patents
Dispersible tablet for eliminating inflammation and preparation method thereof Download PDFInfo
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- CN1840065A CN1840065A CN 200610032658 CN200610032658A CN1840065A CN 1840065 A CN1840065 A CN 1840065A CN 200610032658 CN200610032658 CN 200610032658 CN 200610032658 A CN200610032658 A CN 200610032658A CN 1840065 A CN1840065 A CN 1840065A
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Abstract
The invention relates to a dispersible tablet for treating respiratory tract inflammation, bronchitis, pneumonia, acute tonsillitis, urinary system infection and biliary tract infection. The preparing process comprises the steps of disintegrating into fines, water grilling, concentrating to clear grease, and charging right amount of auxiliary materials.
Description
Affiliated technical field:
The invention belongs to pharmaceutical, it mainly is to be used for respiratory tract infection, bronchitis, pneumonia, acute tonsillitis, also can be used for urinary system infection, biliary tract infection.Be a kind of dispersible tablet for eliminating inflammation and preparation method specifically.
Background technology:
At present, also do not find to have similar products and preparation method thereof on the market.
Summary of the invention:
The technical solution used in the present invention is: dispersible tablet for eliminating inflammation of the present invention and preparation method is characterized in that: quantitatively Radix Scutellariae, that Mentholum is ground into fine powder is standby; Radix Scrophulariae, Radix Gentianae, Gypsum Fibrosum, Radix Bupleuri, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scutellariae, more than seven flavors, decocting boils that to be concentrated into clear paste standby; Then with above-mentioned standby material, make dispersible tablet and finish a whole set of manufacture method by national standard prescription the requirements adding appropriate amount of auxiliary materials that feeds intake.This medicine is dosage form technological innovation on existing capsular basis, and agent changes into takes more conveniently, and the dispersible tablet that onset is more fast is benefited the common people.This medicine expelling pathogen from the exterior and clearing up internal heat, heat-clearing and toxic substances removing.Be used for respiratory tract infection, bronchitis, pneumonia, acute tonsillitis.Also can be used for urinary system infection, biliary tract infection.Dispersible tablet is met water disintegrate fast, and is more easy for patients to accept and be ready to take, and carry, easy to use, be clinical welcome and safe, stable, effective medicine, be the ideal product of modern pharmaceutical enterprise.
Formula constituent of the present invention is: the hot clear extractum 161g simple making method of Radix Scutellariae 137g Mentholum 2g is ground into fine powder for Radix Scutellariae drying under reduced pressure in the side; Hot clear extractum prescription and method for making are: Radix Scrophulariae 308.73g Radix Gentianae 205.20g Gypsum Fibrosum 617.46g Radix Bupleuri 205.20g Fructus Gardeniae 205.20g Rhizoma Anemarrhenae 205.20g Radix Scutellariae 147.79g, more than seven flavors, decoct with water secondary, each 1.5 hours, collecting decoction filtered, filtrate decompression is concentrated into thick paste, adds Radix Scutellariae powder, mixing, drying under reduced pressure is ground into fine powder, adds Mentholum and appropriate amount of auxiliary materials, mixing, full powder compaction dispersible tablet is made 1000, promptly.
The preparation method characteristic of the hot Yiqing dispersing tablets of the present invention is that it may further comprise the steps:
(1) in the technology in the preparation of hot clear extractum, Radix Scrophulariae, Radix Gentianae, Gypsum Fibrosum, Radix Bupleuri, Fructus Gardeniae, the Rhizoma Anemarrhenae, radix scutellariae medicinal materials are ground into coarse powder and are generally 5-30 purpose coarse powder or are cut into decoction pieces, are preferably 10 order coarse powder or are cut into decoction pieces.
(2) decocting of (2) hot clear extractum boils condition: decoct with water 2-3 time, amount of water is 6-12 times of dose for the first time, is for the second time 4-10 times of dose, and the time is each 1-2 hour.The best is: decoct with water 2 times, amount of water is 8 times of dose for the first time, is for the second time 6 times of dose, and the time is each 1.5 hours.
(3) hot clear extractum method for concentration is in the technology: heating in water bath concentrates or concentrating under reduced pressure.
(4) the spissated temperature of heating in water bath is 50-100 ℃ in the technology, and the best is: 60-80 ℃.
(5) temperature of water-bath concentrating under reduced pressure is 50-80 ℃ in the technology, and the best is: 60-75 ℃.
(6) added adjuvant is in the following adjuvant one or more in the technology: microcrystalline Cellulose, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc.
(7) added supplementary product consumption is in the technology: 5-50% microcrystalline Cellulose, 3-30% low-substituted hydroxypropyl cellulose, 3-30% carboxymethyl starch sodium, 3-30% polyvinylpolypyrrolidone, 3-30% cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc. are an amount of.
(8) feed intake after above standby material is converted by requirements of national standard prescription, mix, direct dry powder sheeting or pelletizing press sheet promptly get hot Yiqing dispersing tablets.
The invention has the beneficial effects as follows: more easy for patients to accept and be ready to take, and carry, easy to use, be clinical welcome and safe, stable, effective medicine, be the ideal product of modern pharmaceutical enterprise.
Embodiment:
Dispersible tablet for eliminating inflammation of the present invention and preparation method is characterized in that: quantitatively Radix Scutellariae, that Mentholum is ground into fine powder is standby; Radix Scrophulariae, Radix Gentianae, Gypsum Fibrosum, Radix Bupleuri, Fructus Gardeniae, the Rhizoma Anemarrhenae, Radix Scutellariae, more than seven flavors, decocting boils that to be concentrated into clear paste standby; Then with above-mentioned standby material, make dispersible tablet and finish a whole set of manufacture method by national standard prescription the requirements adding appropriate amount of auxiliary materials that feeds intake.This medicine is dosage form technological innovation on existing capsular basis, and agent changes into takes more conveniently, and the dispersible tablet that onset is more fast is benefited the common people.This medicine expelling pathogen from the exterior and clearing up internal heat, heat-clearing and toxic substances removing.Be used for respiratory tract infection, bronchitis, pneumonia, acute tonsillitis.Also can be used for urinary system infection, biliary tract infection.Dispersible tablet is met water disintegrate fast, and is more easy for patients to accept and be ready to take, and carry, easy to use, be clinical welcome and safe, stable, effective medicine, be the ideal product of modern pharmaceutical enterprise.
Formula constituent of the present invention is: the hot clear extractum 161g simple making method of Radix Scutellariae 137g Mentholum 2g is ground into fine powder for Radix Scutellariae drying under reduced pressure in the side; Hot clear extractum prescription and method for making are: Radix Scrophulariae 308.73g Radix Gentianae 205.20g Gypsum Fibrosum 617.46g Radix Bupleuri 205.20g Fructus Gardeniae 205.20g Rhizoma Anemarrhenae 205.20g Radix Scutellariae 147.79g, more than seven flavors, decoct with water secondary, each 1.5 hours, collecting decoction filtered, filtrate decompression is concentrated into thick paste, adds Radix Scutellariae powder, mixing, drying under reduced pressure is ground into fine powder, adds Mentholum and appropriate amount of auxiliary materials, mixing, full powder compaction dispersible tablet is made 1000, promptly.
The preparation method characteristic of the hot Yiqing dispersing tablets of the present invention is that it may further comprise the steps:
1, in the skill in the preparation of hot clear extractum, Radix Scrophulariae, Radix Gentianae, Gypsum Fibrosum, Radix Bupleuri, Fructus Gardeniae, the Rhizoma Anemarrhenae, radix scutellariae medicinal materials are ground into coarse powder and are generally 5-30 purpose coarse powder or are cut into decoction pieces, are preferably 10 order coarse powder or are cut into decoction pieces.
2, the decocting of hot clear extractum boils condition: decoct with water 2-3 time, amount of water is 6-12 times of dose for the first time, is for the second time 4-10 times of dose, and the time is each 1-2 hour.The best is: decoct with water 2 times, amount of water is 8 times of dose for the first time, is for the second time 6 times of dose, and the time is each 1.5 hours.
3, hot clear extractum method for concentration is in the technology: heating in water bath concentrates or concentrating under reduced pressure.
4, the spissated temperature of heating in water bath is 50-100 ℃ in the technology, and the best is: 60-80 ℃
5, the temperature of water-bath concentrating under reduced pressure is 50-80 ℃ in the technology, and the best is: 60-75 ℃
6, added adjuvant is in the following adjuvant one or more in the technology: microcrystalline Cellulose, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc.
7, added supplementary product consumption is in the technology: 5-50% microcrystalline Cellulose, 3-30% low-substituted hydroxypropyl cellulose, 3-30% carboxymethyl starch sodium, 3-30% polyvinylpolypyrrolidone, 3-30% cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc. are an amount of.
8, feed intake after above standby material is converted by requirements of national standard prescription, mix, direct dry powder sheeting or pelletizing press sheet promptly get hot Yiqing dispersing tablets.
The present invention is more easy for patients to accept and be ready to take, and carry, easy to use, be clinical welcome and safe, stable, effective medicine, be the ideal product of modern pharmaceutical enterprise.
Claims (3)
1, a kind of dispersible tablet for eliminating inflammation and preparation method, it is characterized in that: formula constituent of the present invention is: the hot clear extractum 161g of Radix Scutellariae 137g Mentholum 2g, hot clear extractum component is: Radix Scrophulariae 308.73g Radix Gentianae 205.20g Gypsum Fibrosum 617.46g Radix Bupleuri 205.20g Fructus Gardeniae 205.20g Rhizoma Anemarrhenae 205.20g Radix Scutellariae 147.79g.
2, dispersible tablet for eliminating inflammation according to claim 1 and preparation method, its manufacture method is characterised in that: above seven flavors decoct with water secondary, each 1.5 hours, collecting decoction filtered, filtrate decompression is concentrated into thick paste, adds Radix Scutellariae powder, mixing, drying under reduced pressure is ground into fine powder, adds Mentholum and appropriate amount of auxiliary materials, mixing, full powder compaction dispersible tablet is made 1000, promptly.
3, dispersible tablet for eliminating inflammation according to claim 1 and preparation method, its manufacture method is characterised in that: it may further comprise the steps: 1, in the preparation of the clear extractum of middle sweltering heat, Radix Scrophulariae, Radix Gentianae, Gypsum Fibrosum, Radix Bupleuri, Fructus Gardeniae, the Rhizoma Anemarrhenae, radix scutellariae medicinal materials are ground into coarse powder and are generally 5-30 purpose coarse powder or are cut into decoction pieces, are preferably 10 order coarse powder or are cut into decoction pieces; 2, the decocting of hot clear extractum boils condition: decoct with water 2-3 time, amount of water is 6-12 times of dose for the first time, is for the second time 4-10 times of dose, and the time is each 1-2 hour.The best is: decoct with water 2 times, amount of water is 8 times of dose for the first time, is for the second time 6 times of dose, and the time is each 1.5 hours; 3, hot clear extractum method for concentration is in the technology: heating in water bath concentrates or concentrating under reduced pressure; 4, the spissated temperature of heating in water bath is 50-100 ℃ in the technology, and the best is: 60-80 ℃; 5, the temperature of water-bath concentrating under reduced pressure is 50-80 ℃ in the technology, and the best is: 60-75 ℃; 6, added adjuvant is in the following adjuvant one or more in the technology: microcrystalline Cellulose, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc.; 7, added supplementary product consumption is in the technology: 5-50% microcrystalline Cellulose, 3-30% low-substituted hydroxypropyl cellulose, 3-30% carboxymethyl starch sodium, 3-30% polyvinylpolypyrrolidone, 3-30% cross-linking sodium carboxymethyl cellulose, and Pulvis Talci, starch, magnesium stearate etc. are an amount of; 8, feed intake after above standby material is converted by requirements of national standard prescription, mix, direct dry powder sheeting or pelletizing press sheet promptly get hot Yiqing dispersing tablets.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610032658 CN1840065A (en) | 2006-01-05 | 2006-01-05 | Dispersible tablet for eliminating inflammation and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200610032658 CN1840065A (en) | 2006-01-05 | 2006-01-05 | Dispersible tablet for eliminating inflammation and preparation method thereof |
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| CN1840065A true CN1840065A (en) | 2006-10-04 |
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| CN 200610032658 Pending CN1840065A (en) | 2006-01-05 | 2006-01-05 | Dispersible tablet for eliminating inflammation and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101919960A (en) * | 2010-08-30 | 2010-12-22 | 海南新中正制药有限公司 | Inflammation and heat clearing tablets and preparation method thereof |
| CN102145110A (en) * | 2011-03-24 | 2011-08-10 | 卞合香 | Oral medicine composition for clinically nursing high fever caused by infantile respiratory tract infection and preparation method of oral medicine composition |
| CN103272030A (en) * | 2013-05-31 | 2013-09-04 | 武伟 | Pneumonic treatment medicine and preparation method thereof |
-
2006
- 2006-01-05 CN CN 200610032658 patent/CN1840065A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101919960A (en) * | 2010-08-30 | 2010-12-22 | 海南新中正制药有限公司 | Inflammation and heat clearing tablets and preparation method thereof |
| CN101919960B (en) * | 2010-08-30 | 2012-06-27 | 海南新中正制药有限公司 | Inflammation and heat clearing tablets and preparation method thereof |
| CN102145110A (en) * | 2011-03-24 | 2011-08-10 | 卞合香 | Oral medicine composition for clinically nursing high fever caused by infantile respiratory tract infection and preparation method of oral medicine composition |
| CN102145110B (en) * | 2011-03-24 | 2012-06-13 | 卞合香 | Oral medicine composition for clinically nursing high fever caused by infantile respiratory tract infection and preparation method of oral medicine composition |
| CN103272030A (en) * | 2013-05-31 | 2013-09-04 | 武伟 | Pneumonic treatment medicine and preparation method thereof |
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