CN104707106A - Traditional Chinese medicine composition for treating fatty liver and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating fatty liver and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating fatty liver and a preparation method thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicinal materials in parts by weight: 7-15 parts of salvia miltiorrhiza, 3-10 parts of hawthorn, 4-8 parts of fleece-flower roots, 2-4 parts of semen cassiae, 3-7 parts of cinnamon, 5-12 parts of pericarpium citri reticulatae, 1-6 parts of radix bupleuri, 2-5 parts of liquorice, 2-4 parts of polygonum cuspidatum, 1-3 parts of astragalus membranaceus, 3-6 parts of turmeric, 6-9 parts of red paeony roots, 2-6 parts of rhizoma polygonati and 1-3 parts of schisandra chinensis. The preparation method for the traditional Chinese medicine composition for treating fatty liver comprises the following steps: infrared heating drying, freeze-drying, vacuum microwave drying and mechanical crushing. The prepared traditional Chinese medicine composition for treating fatty liver has a good treatment effect.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine composition and preparation method thereof, particularly relate to a kind of Chinese medicine composition for the treatment of fatty liver and preparation method thereof.
Background technology
Fatty liver, refers to the pathological changes due to overheap fatty in the hepatocyte that a variety of causes causes.The health of the positive serious threat compatriots of fatty liver disease, becomes the second largest hepatopathy being only second to viral hepatitis, has been acknowledged as the common cause of disguised liver cirrhosis.Fatty liver is a kind of common clinical picture, but not one independently disease.The lighter is asymptomatic in its clinical manifestation, and the severe one state of an illness is violent.Generally speaking, fatty liver belongs to reversibility disease, and early diagnosis also treatment in time often can recover normal.
Pathogenesis of fatty liver reason is caused by following reason usually: 1. obese fatty liver: the degree that intrahepatic fat is piled up is directly proportional to body weight.The obesity of 30% ~ 50% merges fatty liver, and severe obesity fatty liver variability is up to 61% ~ 94%.After obese people's body weight obtains control, its fatty infiltration also reduces or disappears; 2. alcoholic fatty liver: long-term alcoholic needle biopsy of liver, 75% ~ 95% has fatty infiltration.Somebody observes, and the incidence rate of the then alcoholic fatty liver of drinking every day more than 80 ~ 160 grams increases by 5 ~ 25 times; 3. quick weight-lossing fatty liver: fasting, too to go on a diet or other quick slimming measures can cause steatolysis to roll up in a short time, consume liver glutathion inside (GSH), malonaldehyde and lipid peroxide in liver are rolled up, and damage hepatocyte, causes fatty liver; 4. dystrophic fatty liver: malnutrition causes potein deficiency to be the major reason causing fatty liver, is more common in ingest deficiency or gastricism, can not synthesize apolipoprotein, thus triglyceride accumulates in liver, forms fatty liver; 5. diabetic fatty liver: in diabetics, about 50% fatty liver can occur is wherein many with adult patient.Because grow up, future trouble diabetes patient has 50% ~ 80% to be overweight people, and its plasma insulin level and blood plasma fatty acid increase, and fatty liver becomes both relevant with obese degree, fatty with feed or sugar is too much relevant again; 6. Drug fatty liver: some drugs or chemical toxicant cause fatty liver by the synthesis of Profilin matter, as tetracycline, adrenocortical hormone, puromycin, ring amine, ipecine and arsenic, lead, silver, hydrargyrum etc.Lipid lowerers also forms fatty liver by disturbing the metabolism of lipoprotein; 7. pregnancy fatty liver: how fall ill during the first tire gestation 34 ~ 40 weeks, be in a bad way, prognosis is not good, and mother and baby's mortality rate reaches 80% and 70% respectively; 8. the fatty liver that causes of other diseases: when tuberculosis, bacterial pneumonia and septicemia etc. infect, fatty liver also can occur, if the undue restraint of viral hepatitis, add and take in high sugar, high caloric diet, hepatocyte fat is easily piled up; After accepting corticosteroid therapy, fatty liver more easily occurs.After infection control or remove fatty liver after the cause of disease and improve rapidly, also has the fatty liver etc. that so-called parenteral hyperalimentation fatty liver, toxic fatty liver, hereditary cause.
The compositions of license publication number to be the disclosure of the invention of CN102596214A improve fatty liver, composition comprises at least one extract in Fructus Lycopersici esculenti herb extract, hemlock chervil extract and Radix Arnebiae extract.Its invention selection is simply prepared easy, but can only play the effect slowing down disease, and cannot cure.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of fatty liver and preparation method thereof to overcome above the deficiencies in the prior art.
Technical scheme: the invention discloses a kind of Chinese medicine composition for the treatment of fatty liver, the Chinese medicine composition of described treatment fatty liver comprises following composition by weight: Radix Salviae Miltiorrhizae 7 ~ 15 parts, Fructus Crataegi 3 ~ 10 parts, the Radix Polygoni Multiflori 4 ~ 8 parts, Semen Cassiae 2 ~ 4 parts, Cortex Cinnamomi 3 ~ 7 parts, Pericarpium Citri Reticulatae 5 ~ 12 parts, Radix Bupleuri 1 ~ 6 part, 2 ~ 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 ~ 4 parts, the Radix Astragali 1 ~ 3 part and 3 ~ 6 parts, Rhizoma Curcumae Longae.
Preferably, described a kind of Chinese medicine composition for the treatment of fatty liver, the Chinese crude drug in tea bag comprises following composition by weight: Radix Salviae Miltiorrhizae 7 ~ 15 parts, Fructus Crataegi 3 ~ 10 parts, the Radix Polygoni Multiflori 4 ~ 8 parts, Semen Cassiae 2 ~ 4 parts, Cortex Cinnamomi 3 ~ 7 parts, Pericarpium Citri Reticulatae 5 ~ 12 parts, Radix Bupleuri 1 ~ 6 part, 2 ~ 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 ~ 4 parts, the Radix Astragali 1 ~ 3 part, 3 ~ 6 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 6 ~ 9 parts, Rhizoma Polygonati 2 ~ 6 parts and Fructus Schisandrae Chinensis 1 ~ 3 part.
Preferably, described a kind of Chinese medicine composition for the treatment of fatty liver, the Chinese crude drug in tea bag comprises following composition by weight: Radix Salviae Miltiorrhizae 10 ~ 12 parts, Fructus Crataegi 4 ~ 7 parts, the Radix Polygoni Multiflori 5 ~ 6 parts, Semen Cassiae 2 ~ 3 parts, Cortex Cinnamomi 3 ~ 5 parts, Pericarpium Citri Reticulatae 7 ~ 10 parts, Radix Bupleuri 2 ~ 4 parts, 2 ~ 3 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 3 ~ 4 parts, the Radix Astragali 2 ~ 3 parts, 3 ~ 5 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 7 ~ 8 parts, Rhizoma Polygonati 4 ~ 5 parts and Fructus Schisandrae Chinensis 2 ~ 3 parts.
Preferably, described a kind of Chinese medicine composition for the treatment of fatty liver, the Chinese crude drug in tea bag comprises following composition by weight: Radix Salviae Miltiorrhizae 11 parts, Fructus Crataegi 5 parts, the Radix Polygoni Multiflori 6 parts, Semen Cassiae 3 parts, Cortex Cinnamomi 4 parts, Pericarpium Citri Reticulatae 8 parts, Radix Bupleuri 3 parts, 2 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 4 parts, the Radix Astragali 2 parts, 4 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 7 parts, Rhizoma Polygonati 4 parts and Fructus Schisandrae Chinensis 2 parts.
A preparation method for the Chinese medicine composition for the treatment of fatty liver and preparation method thereof, comprises the steps:
Step one, cleans all medical materials with clear water;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, respectively the Chinese crude drug of above-mentioned oven dry is ground after Infrared Heating drying, getting Radix Salviae Miltiorrhizae 7 ~ 15 parts, Fructus Crataegi 3 ~ 10 parts, the Radix Polygoni Multiflori 4 ~ 8 parts, Semen Cassiae 2 ~ 4 parts and Cortex Cinnamomi 3 ~ 7 parts after strainer filtering more respectively, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, respectively above-mentioned lyophilized products is ground after lyophilization, getting Pericarpium Citri Reticulatae 5 ~ 12 parts, Radix Bupleuri 1 ~ 6 part, 2 ~ 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 ~ 4 parts, the Radix Astragali 1 ~ 3 part and 3 ~ 6 parts, Rhizoma Curcumae Longae after strainer filtering more respectively, is B powder after mixing;
These three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing, after fragmentation by step 4 respectively, carry out vacuum microwave drying, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 6 ~ 9 parts, Rhizoma Polygonati 2 ~ 6 parts and Fructus Schisandrae Chinensis 1 ~ 3 part after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
Preferably, described a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver, step 2, the filter screen particle diameter described in three and four are 80 orders.
Preferably, described a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver, the baking temperature of the Infrared Heating drying described in step 2 is 55 DEG C, and drying time is 1 ~ 2 hour.
Preferably, described a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver, the cryodesiccated baking temperature described in step 3 is-10 DEG C, and sublimation drying is 4 ~ 6 hours.
Preferably, described a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver, the baking temperature of the vacuum microwave drying described in step 4 is 45 DEG C, and vacuum is 200Pa, and microwave power is 800w.
Beneficial effect: along with the raising of people's living standard, obesity becomes a kind of trend, and the rate of suffering from of fatty liver increases year by year, and the western medical treatment time is long, less effective, and life-time service has untoward reaction.Chinese medicine, then based on depressed liver-energy dispersing and QI regulating, can slowly effectively be treated.The Chinese medicine composition that the present invention makes has the advantages that raw material is easy to get, preparation technology is simple and evident in efficacy.When Radix Salviae Miltiorrhizae 11 parts, Fructus Crataegi 5 parts, the Radix Polygoni Multiflori 6 parts, Semen Cassiae 3 parts, Cortex Cinnamomi 4 parts, Pericarpium Citri Reticulatae 8 parts, Radix Bupleuri 3 parts, 2 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 4 parts, the Radix Astragali 2 parts, 4 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 7 parts, Rhizoma Polygonati 4 parts and Fructus Schisandrae Chinensis 2 parts time, the drug effect of Chinese medicine composition is best.
Detailed description of the invention
Embodiment 1
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, the baking temperature of Infrared Heating drying is 55 DEG C, and drying time is 1 hour, is ground by the Chinese crude drug of above-mentioned oven dry respectively after Infrared Heating drying, using particle diameter to be get Radix Salviae Miltiorrhizae 7 parts, Fructus Crataegi 10 parts, the Radix Polygoni Multiflori 4 parts, Semen Cassiae 4 parts and Cortex Cinnamomi 3 parts more respectively after 80 object strainer filterings, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, cryodesiccated baking temperature is-10 DEG C, and sublimation drying is 6 hours, is ground by above-mentioned lyophilized products respectively after lyophilization, using particle diameter to be get Pericarpium Citri Reticulatae 5 parts, Radix Bupleuri 6 parts, 2 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 4 parts, the Radix Astragali 1 part and 6 parts, Rhizoma Curcumae Longae more respectively after 80 object filter screen strainer filterings, is B powder after mixing;
Step 4, these three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing respectively, after fragmentation, carry out vacuum microwave drying, the baking temperature of vacuum microwave drying is 45 DEG C, and vacuum is 200Pa, microwave power is 800w, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 6 parts, Rhizoma Polygonati 6 parts and Fructus Schisandrae Chinensis 1 part after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
Embodiment 2
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, the baking temperature of Infrared Heating drying is 55 DEG C, and drying time is 2 hours, is ground by the Chinese crude drug of above-mentioned oven dry respectively after Infrared Heating drying, using particle diameter to be get Radix Salviae Miltiorrhizae 15 parts, Fructus Crataegi 3 parts, the Radix Polygoni Multiflori 8 parts, Semen Cassiae 2 parts and Cortex Cinnamomi 3 parts more respectively after 80 object strainer filterings, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, cryodesiccated baking temperature is-10 DEG C, and sublimation drying is 4 hours, is ground by above-mentioned lyophilized products respectively after lyophilization, using particle diameter to be get Pericarpium Citri Reticulatae 12 parts, Radix Bupleuri 1 part, 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 parts, the Radix Astragali 3 parts and 3 parts, Rhizoma Curcumae Longae more respectively after 80 object filter screen strainer filterings, is B powder after mixing;
Step 4, these three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing respectively, after fragmentation, carry out vacuum microwave drying, the baking temperature of vacuum microwave drying is 45 DEG C, and vacuum is 200Pa, microwave power is 800w, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 9 parts, Rhizoma Polygonati 2 parts and Fructus Schisandrae Chinensis 3 parts after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
Embodiment 3
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, the baking temperature of Infrared Heating drying is 55 DEG C, and drying time is 1 hour, is ground by the Chinese crude drug of above-mentioned oven dry respectively after Infrared Heating drying, using particle diameter to be get Radix Salviae Miltiorrhizae 10 parts, Fructus Crataegi 7 parts, the Radix Polygoni Multiflori 5 parts, Semen Cassiae 3 parts and Cortex Cinnamomi 3 parts more respectively after 80 object strainer filterings, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, cryodesiccated baking temperature is-10 DEG C, and sublimation drying is 4 hours, is ground by above-mentioned lyophilized products respectively after lyophilization, using particle diameter to be get Pericarpium Citri Reticulatae 7 parts, Radix Bupleuri 4 parts, 2 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 4 parts, the Radix Astragali 2 parts and 5 parts, Rhizoma Curcumae Longae more respectively after 80 object filter screen strainer filterings, is B powder after mixing;
Step 4, these three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing respectively, after fragmentation, carry out vacuum microwave drying, the baking temperature of vacuum microwave drying is 45 DEG C, and vacuum is 200Pa, microwave power is 800w, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 7 parts, Rhizoma Polygonati 5 parts and Fructus Schisandrae Chinensis 2 parts after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
Embodiment 4
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, the baking temperature of Infrared Heating drying is 55 DEG C, and drying time is 2 hours, is ground by the Chinese crude drug of above-mentioned oven dry respectively after Infrared Heating drying, using particle diameter to be get Radix Salviae Miltiorrhizae 12 parts, Fructus Crataegi 4 parts, the Radix Polygoni Multiflori 6 parts, Semen Cassiae 2 parts and Cortex Cinnamomi 5 parts more respectively after 80 object strainer filterings, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, cryodesiccated baking temperature is-10 DEG C, and sublimation drying is 6 hours, is ground by above-mentioned lyophilized products respectively after lyophilization, using particle diameter to be get Pericarpium Citri Reticulatae 10 parts, Radix Bupleuri 2 parts, 3 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 3 parts, the Radix Astragali 3 parts and 3 parts, Rhizoma Curcumae Longae more respectively after 80 object filter screen strainer filterings, is B powder after mixing;
Step 4, these three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing respectively, after fragmentation, carry out vacuum microwave drying, the baking temperature of vacuum microwave drying is 45 DEG C, and vacuum is 200Pa, microwave power is 800w, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 8 parts, Rhizoma Polygonati 4 parts and Fructus Schisandrae Chinensis 3 parts after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
Embodiment 5
Step one, with all medical materials of the clean water of 20 DEG C;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, the baking temperature of Infrared Heating drying is 55 DEG C, and drying time is 1.5 hours, is ground by the Chinese crude drug of above-mentioned oven dry respectively after Infrared Heating drying, using particle diameter to be get Radix Salviae Miltiorrhizae 11 parts, Fructus Crataegi 5 parts, the Radix Polygoni Multiflori 6 parts, Semen Cassiae 3 parts and Cortex Cinnamomi 4 parts more respectively after 80 object strainer filterings, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, cryodesiccated baking temperature is-10 DEG C, and sublimation drying is 5 hours, is ground by above-mentioned lyophilized products respectively after lyophilization, using particle diameter to be get Pericarpium Citri Reticulatae 8 parts, Radix Bupleuri 3 parts, 2 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 4 parts, the Radix Astragali 2 parts and 4 parts, Rhizoma Curcumae Longae more respectively after 80 object filter screen strainer filterings, is B powder after mixing;
Step 4, these three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing respectively, after fragmentation, carry out vacuum microwave drying, the baking temperature of vacuum microwave drying is 45 DEG C, and vacuum is 200Pa, microwave power is 800w, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 7 parts, Rhizoma Polygonati 4 parts and Fructus Schisandrae Chinensis 2 parts after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
Comparative example
The invention formula being CN102596214A according to license publication number makes the compositions improving fatty liver, the leaf of the Fructus Lycopersici esculenti herb chopped up by 1kg, stem and root are soaked in the ethanol of 5 liter 50%, remove after extracting 10 hours at 50 DEG C and extract residue, then remove Extraction solvent through concentrating under reduced pressure and obtain the extract of solid phase.
Compositions embodiment 1 to 5 prepared and the extract that comparative example prepares use to the Patients with Fatty Liver suffering from the different state of an illness of weight respectively, slight patient 50 people, severe patient 50 people, user is each serving with 2g, morning, noon and afternoon are each once, and the result after use is as following table:
Table 1 embodiment 1-5 and comparative example are to the Contrast on effect after using
As known from Table 1, license publication number be the compositions tool of improvement fatty liver prepared by the invention of CN102596214A have some improvement treatment effect, but therapeutic effect is general.The Chinese medicine composition for the treatment of fatty liver of the present invention not only well can play the effect for the treatment of fatty liver, has more very high cure rate.
Claims (9)
1. treat the Chinese medicine composition of fatty liver for one kind, it is characterized in that, the Chinese medicine composition of described treatment fatty liver comprises following composition by weight: Radix Salviae Miltiorrhizae 7 ~ 15 parts, Fructus Crataegi 3 ~ 10 parts, the Radix Polygoni Multiflori 4 ~ 8 parts, Semen Cassiae 2 ~ 4 parts, Cortex Cinnamomi 3 ~ 7 parts, Pericarpium Citri Reticulatae 5 ~ 12 parts, Radix Bupleuri 1 ~ 6 part, 2 ~ 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 ~ 4 parts, the Radix Astragali 1 ~ 3 part and 3 ~ 6 parts, Rhizoma Curcumae Longae.
2. a kind of Chinese medicine composition for the treatment of fatty liver according to claim 1, it is characterized in that, the Chinese medicine composition of described treatment fatty liver comprises following composition by weight: Radix Salviae Miltiorrhizae 7 ~ 15 parts, Fructus Crataegi 3 ~ 10 parts, the Radix Polygoni Multiflori 4 ~ 8 parts, Semen Cassiae 2 ~ 4 parts, Cortex Cinnamomi 3 ~ 7 parts, Pericarpium Citri Reticulatae 5 ~ 12 parts, Radix Bupleuri 1 ~ 6 part, 2 ~ 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 ~ 4 parts, the Radix Astragali 1 ~ 3 part, 3 ~ 6 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 6 ~ 9 parts, Rhizoma Polygonati 2 ~ 6 parts and Fructus Schisandrae Chinensis 1 ~ 3 part.
3. a kind of Chinese medicine composition for the treatment of fatty liver according to claim 2, it is characterized in that, the Chinese medicine composition of described treatment fatty liver comprises following composition by weight: Radix Salviae Miltiorrhizae 10 ~ 12 parts, Fructus Crataegi 4 ~ 7 parts, the Radix Polygoni Multiflori 5 ~ 6 parts, Semen Cassiae 2 ~ 3 parts, Cortex Cinnamomi 3 ~ 5 parts, Pericarpium Citri Reticulatae 7 ~ 10 parts, Radix Bupleuri 2 ~ 4 parts, 2 ~ 3 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 3 ~ 4 parts, the Radix Astragali 2 ~ 3 parts, 3 ~ 5 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 7 ~ 8 parts, Rhizoma Polygonati 4 ~ 5 parts and Fructus Schisandrae Chinensis 2 ~ 3 parts.
4. a kind of Chinese medicine composition for the treatment of fatty liver according to claim 2, it is characterized in that, the Chinese medicine composition of described treatment fatty liver comprises following composition by weight: Radix Salviae Miltiorrhizae 11 parts, Fructus Crataegi 5 parts, the Radix Polygoni Multiflori 6 parts, Semen Cassiae 3 parts, Cortex Cinnamomi 4 parts, Pericarpium Citri Reticulatae 8 parts, Radix Bupleuri 3 parts, 2 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 4 parts, the Radix Astragali 2 parts, 4 parts, Rhizoma Curcumae Longae, Radix Paeoniae Rubra 7 parts, Rhizoma Polygonati 4 parts and Fructus Schisandrae Chinensis 2 parts.
5. a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver according to claim 2, it is characterized in that, described preparation method comprises the steps:
Step one, cleans all medical materials with clear water;
Step 2, Radix Salviae Miltiorrhizae, Fructus Crataegi, the Radix Polygoni Multiflori, Semen Cassiae and Cortex Cinnamomi are carried out Mechanical Crushing first respectively, after fragmentation, carry out Infrared Heating drying again, respectively the Chinese crude drug of above-mentioned oven dry is ground after Infrared Heating drying, getting Radix Salviae Miltiorrhizae 7 ~ 15 parts, Fructus Crataegi 3 ~ 10 parts, the Radix Polygoni Multiflori 4 ~ 8 parts, Semen Cassiae 2 ~ 4 parts and Cortex Cinnamomi 3 ~ 7 parts after strainer filtering more respectively, is A powder after mixing;
Step 3, these six kinds of raw materials of Pericarpium Citri Reticulatae, Radix Bupleuri, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati, the Radix Astragali and Rhizoma Curcumae Longae are carried out Mechanical Crushing respectively, after fragmentation, carry out lyophilization again, respectively above-mentioned lyophilized products is ground after lyophilization, getting Pericarpium Citri Reticulatae 5 ~ 12 parts, Radix Bupleuri 1 ~ 6 part, 2 ~ 5 parts, Radix Glycyrrhizae, Rhizoma Polygoni Cuspidati 2 ~ 4 parts, the Radix Astragali 1 ~ 3 part and 3 ~ 6 parts, Rhizoma Curcumae Longae after strainer filtering more respectively, is B powder after mixing;
These three kinds of raw materials of Radix Paeoniae Rubra, Rhizoma Polygonati and Fructus Schisandrae Chinensis are carried out Mechanical Crushing, after fragmentation by step 4 respectively, carry out vacuum microwave drying, being ground by above-mentioned Chinese crude drug respectively after drying, get Radix Paeoniae Rubra 6 ~ 9 parts, Rhizoma Polygonati 2 ~ 6 parts and Fructus Schisandrae Chinensis 1 ~ 3 part after strainer filtering more respectively, is C powder after mixing;
Step 5, then by A powder, B powder and C powder mixing and stirring, gained mixture is the Chinese medicine composition for the treatment of fatty liver.
6. a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver according to claim 5, is characterized in that, in described preparation method, step 2, the filter screen particle diameter described in three and four are 80 orders.
7. a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver according to claim 5, is characterized in that, the baking temperature of the Infrared Heating drying in described preparation method described in step 2 is 55 DEG C, and drying time is 1 ~ 2 hour.
8. a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver according to claim 5, is characterized in that, the cryodesiccated baking temperature in described preparation method described in step 3 is-10 DEG C, and sublimation drying is 4 ~ 6 hours.
9. a kind of preparation method for the treatment of the Chinese medicine composition of fatty liver according to claim 5, is characterized in that, in described preparation method, the baking temperature of the vacuum microwave drying described in step 4 is 45 DEG C, and vacuum is 200Pa, and microwave power is 800w.
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| CN201510116796.1A CN104707106A (en) | 2015-03-18 | 2015-03-18 | Traditional Chinese medicine composition for treating fatty liver and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311614A (en) * | 2015-12-13 | 2016-02-10 | 王金国 | Traditional Chinese medicine cream formula applied to fatty liver and preparation method |
| CN115869358A (en) * | 2022-12-13 | 2023-03-31 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating non-alcoholic fatty liver disease and application thereof |
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| JP2006036788A (en) * | 2004-06-30 | 2006-02-09 | Morishita Jintan Kk | Fat metabolism-improving composition |
| CN103120742A (en) * | 2013-02-28 | 2013-05-29 | 石家庄市第五医院 | Traditional Chinese medicine capsule for treating fatty liver and alcoholic liver and preparation method thereof |
| CN103341035A (en) * | 2013-06-27 | 2013-10-09 | 刁吉祥 | Radix bupleuri lipid-lowering soup |
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| JP2006036788A (en) * | 2004-06-30 | 2006-02-09 | Morishita Jintan Kk | Fat metabolism-improving composition |
| CN103120742A (en) * | 2013-02-28 | 2013-05-29 | 石家庄市第五医院 | Traditional Chinese medicine capsule for treating fatty liver and alcoholic liver and preparation method thereof |
| CN103341035A (en) * | 2013-06-27 | 2013-10-09 | 刁吉祥 | Radix bupleuri lipid-lowering soup |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105311614A (en) * | 2015-12-13 | 2016-02-10 | 王金国 | Traditional Chinese medicine cream formula applied to fatty liver and preparation method |
| CN115869358A (en) * | 2022-12-13 | 2023-03-31 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating non-alcoholic fatty liver disease and application thereof |
| CN115869358B (en) * | 2022-12-13 | 2023-09-05 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine composition for treating non-alcoholic fatty liver disease and application thereof |
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Application publication date: 20150617 |