CN1839924A

CN1839924A - Nephritis-treating medicine and its preparation method

Info

Publication number: CN1839924A
Application number: CN 200610200099
Authority: CN
Inventors: 李家斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-02-07
Filing date: 2006-02-07
Publication date: 2006-10-04
Anticipated expiration: 2026-02-07
Also published as: CN100406031C

Abstract

The invention relates to a pharmaceutical composition for treating nephritis and process for preparation, which is prepared from lysimachia christinae, subprostrate sophora root, Lygodiaceae and red ginseng.

Description

Medicine of treatment nephritis and preparation method thereof

Technical field:

The present invention relates to a kind of medicine for the treatment of nephritis and preparation method thereof, belong to technical field of medicaments.

Background technology:

Nephritis is a kind of common disease of internal medicine and department of pediatrics, acute nephritis claims acute glomerulonephritis again, mean that broadly one group of cause of disease and pathogeny differ, but show as Acute onset clinically, drop to the renal glomerular disease of characteristics with hematuria, albuminuria, edema, hypertension and glomerular filtration rate, so also often be called acute nephritic syndrome.Most clinically acute poststreptococcal glomerulonephritises that belong to.This disease is modal a kind of nephropathy in children's's period.Age, rare below 2 years old, M-F was about 2: 1 more to see 3～8 years old.Its sickness rate is more common in child and teenager.Edema and oliguria are the characteristics of primary disease, and primary disease reacts as a kind of premunition, often are secondary to after the streptococcal infection of upper respiratory tract or skin.Originally mostly good after recovering, do not stay any sequela, if but the morbidity early time treatment is improper, or some cases with severe, then can transfer chronic nephritis even renal failure to, and threat to life.According to the interrelated data statistics, to the child, acute nephritis has 90%～95% cure rate, and it is relatively poor to be grown up, and its cure rate is 68.3%～79%.Chronic nephritis mainly shows as long-term edema, and blood pressure is higher, merges anemia, and albumen, cast etc. are arranged in the urine, and the course of disease of chronic nephritis is longer, and does not prolongedly heal, and reaching fully, alleviation person only is 4%～21.3%.

At present, the medicament categories of treatment nephritis has a lot, but all because of growing the course of treatment, take effect slowly, easily show effect repeatedly, even due to illness feelings can not be controlled and the severe exacerbation treatment that causes undergoing surgery, and bring unnecessary misery and financial burden to patient.

Summary of the invention:

The objective of the invention is to: provide medicine of a kind of short treating period, instant effect, the difficult treatment nephritis that recurs and preparation method thereof, to overcome the deficiency that prior art exists.

The present invention is achieved in that according to listed as parts by weight it is prepared from for 13～28 parts by 15～30 parts of Herba Lysimachiaes, 10～25 parts of Radix Sophorae Tonkinensiss, 15～25 parts of Spora Lygodii, Radix Ginseng Rubra.

Say that accurately calculate according to weight, it is prepared from by Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g, Radix Ginseng Rubra 18g.

The medicine that the present invention treats nephritis is preparation like this: take by weighing medical material Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g and Radix Ginseng Rubra 18g, shred, put into the chicken tripe of wash clean, chicken is put into pot, steaming and decocting 10～40 minutes, chicken cook the directly edible Carnis Gallus domesticus in back and get final product.

The medicine that the present invention treats nephritis can also prepare like this: take by weighing medical material Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g and Radix Ginseng Rubra 18g, the decocting that adds 2～5 times of medical material amounts boils 1～3 time, each 0.5～2 hour, merges medicinal liquid, medicinal liquid is cooled to 50 ℃～60 ℃, directly takes to get final product.

The traditional Chinese medical science thinks that acute nephritis is by due to invading in ailment said due to cold or exposure, damp and hot, the sore, influences the gasification function of lung, spleen, kidney three warps, so the anxious phase based on eliminating evil, is controlled with clearly suitable dampness removing.Herba Lysimachiae in the side is the dry herb of Primulaceae plant Lysimachia christinae Hance.Summer, Qiu Erji gather.Nature and flavor are sweet, salty, are slightly cold.Return liver, gallbladder, kidney, urinary bladder channel.Have eliminating damp-heat, treating stranguria, the repercussive effect is mainly used in pyretic stranguria, and husky the pouring urinated and puckeryly had a pain jaundice dark coloured urine, carbuncle furuncle, venom, liver and bile stone, the treatment of diseases such as lithangiuria.Radix Sophorae Tonkinensis is the dry root and rhizome of leguminous plant Sophora tonkinensis Gagnep..Excavate autumn, removes impurity, cleaning, drying.The nature and flavor hardship, cold; Poisonous.Attach to the lung and stomach meridians.Have heat-clearing and toxic substances removing, the effect of detumescence sore-throat relieving is mainly used in fire-toxin and pents up, laryngopharynx swelling and pain, the treatment of diseases such as gingivitis.Spora Lygodii, another name: bamboo plantation Sui, net rattan, change rattan ash, Spora Lygodii greatly, climb up by holding on to the ripe spore of pteridophyta Spora Lygodii for Spora Lygodii section is perennial.Gather autumn, dries, and gives birth to and use.Nature and flavor are sweet, and are cold.Return small intestinal, urinary bladder channel.Have the damp and hot of the small intestinal of rushing down, bladder, blood system, inducing diuresis for treating stranguria syndrome, the effect of heat-clearing and toxic substances removing is mainly used in the pyretic stranguria stranguria with blood, damp and hot swelling and ache, oedema due to nephritis, laryngopharynx swelling and pain, the treatment of diseases such as nebulousurine leucorrhea.

Compared with prior art, this product has short treating period, instant effect, is difficult for the advantage of recurrence, the rapid inducing diuresis to remove edema of energy when the nephritis acute attack, and there is not any ADR, child, child, women, old man and anemia of pregnant woman all can take, have no side effect, be difficult for bounce-back after the drug withdrawal, nephritis is had better therapeutic effect.

The present invention proves that through clinical trial nephritis is had better curative effect.Below be the clinical observation on the therapeutic effect of this product treatment nephritis:

One, case:

1, permitted to surpass, the man, 5 years old, be the nephritis patients with mild, transference cure after 1 course of treatment of the Carnis Gallus domesticus through taking medication preparation of the present invention (about about 5 days), through the examination in hospital recovery from illness, tracing observation is recurrence not.

2, Wang Lunqiang, the man 18 years old, is the nephritis patients with mild, recovery from illness after 1 course of treatment of the Carnis Gallus domesticus through taking medication preparation of the present invention (about 5 days).

3, Chen Ling, the woman, 25 years old, there was slight edema in face, confirmed as slight nephritis at examination in hospital, and face's edema disappears after 1 course of treatment of the medicinal liquid through taking medication preparation of the present invention (about 5 days), does not see recurrence so far.

4, Tang Ying, the woman, 13 years old, hydrosarca, edema begins to disappear after 1 course of treatment of the Carnis Gallus domesticus through taking medication preparation of the present invention (about 5 days) afterwards, takes edema complete obiteration after 2 courses of treatment, fully recovers through examination in hospital.

5, Li Wei, the man, 35 years old, once suffered from nephropathy, also go hospitalize, recurrence afterwards, and the state of an illness is more serious, the state of an illness takes a turn for the better to some extent a course of treatment of the Carnis Gallus domesticus through taking medication preparation of the present invention (about 5 days) after, checks recovery from illness after taking 3 courses of treatment, does not recur.

6, Tang Shaohua, the man 59 years old, suffers from nephropathy, anasarca for a long time, difficulty in walking, after the Carnis Gallus domesticus through taking medication preparation of the present invention, edema begins to disappear, take 2 courses of treatment after, edema disappears fully, after the patient has used the medicine of 2 courses of treatment again afterwards, goes the examination in hospital recovery from illness, so far not recurrence.

7, Li Qin, the woman, 28 years old, married more than 3 years, the patient with severe symptoms of nephritis, hydrosarca has hypertension, and with albuminuria and hematuria, once conceived after marriage the mistake 2 times all because of nephropathy, under gynecologist's suggestion, accepted artificial abortion.This patient is at the Carnis Gallus domesticus of having taken medication preparation of the present invention after 1 course of treatment, edema slowly disappears, but albuminuria and hematuria still exist, and after having used the medicine of 2 courses of treatment, removing examination in hospital, all graft functions are normal, blood pressure is normal, albuminuria and hematuria are all normal, and the wish that is over is afterwards given birth to a daughter smoothly.

Two diagnostic criterias:

Typical case's acute nephritis is not difficult to diagnose.After the streptococcal infection, through 1～3 all asymptomatic intermissions, edema, hypertension, hematuria (can accompany albuminuria in various degree) occur, the dynamic change of hemalexin C3 can be clarified a diagnosis in addition again.

Three, Therapeutic Method: medical material directly taken Carnis Gallus domesticus after chicken cooks or medical material decocted with water after take medicinal liquid, 2～3 times on the one, 5 is a course of treatment.

Four, conclusion: comprehensive above-mentioned clinical observation, medicine of the present invention has reached more than 90% the treatment total effective rate of nephritis, and to the good effect of nephritis, instant effect is difficult for recurrence.

The specific embodiment:

Embodiments of the invention 1: take by weighing medical material Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g, Radix Ginseng Rubra 18g, chopping, put into chicken (cock, the hen all can) tripe of wash clean, the weight of chicken is generally best at 2～3 jin, chicken is put into pot, with the slowly steaming and decocting 40 minutes of little fire, chicken cooks the directly edible Carnis Gallus domesticus in back and gets final product.

Embodiments of the invention 2: take by weighing medical material Herba Lysimachiae 15g, Radix Sophorae Tonkinensis 10g, Spora Lygodii 15g, Radix Ginseng Rubra 13g, shred, put into the chicken tripe of wash clean, chicken is put into pot with big fire steaming and decocting 10 minutes, directly eat Carnis Gallus domesticus after chicken cooks and get final product.

Embodiments of the invention 3: take by weighing medical material Herba Lysimachiae 30g, Radix Sophorae Tonkinensis 25g, Spora Lygodii 25g, Radix Ginseng Rubra 28g, shred, put into the chicken tripe of wash clean, chicken is put into pot with moderate heat steaming and decocting 20 minutes, directly eat Carnis Gallus domesticus after chicken cooks and get final product.

Embodiments of the invention 4: take by weighing medical material Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g, Radix Ginseng Rubra 18g, put into the sand jar, the water that in the sand jar, adds 200ml, slowly decocted 20 minutes with fire then, (about 100 ℃ of water temperature) continued to endure 30～40 minutes to treat to open afterwards by water, then medicinal liquid is poured out, when medicinal liquid is cooled to 50 ℃～60 ℃, is directly taken medicinal liquid and get final product.

Embodiments of the invention 5: take by weighing medical material Herba Lysimachiae 15g, Radix Sophorae Tonkinensis 10g, Spora Lygodii 15g, Radix Ginseng Rubra 13g, put into the sand jar, the decocting that adds 2 times of medical material amounts in the sand jar boils 1 time, each 2 hours, merge medicinal liquid, medicinal liquid is cooled to 50 ℃～60 ℃, directly takes medicinal liquid and gets final product.

Embodiments of the invention 6: take by weighing medical material Herba Lysimachiae 30g, Radix Sophorae Tonkinensis 25g, Spora Lygodii 25g, Radix Ginseng Rubra 28g, put into the sand jar, the decocting that adds 5 times of medical material amounts in the sand jar boils 3 times, each 0.5 hour, merge medicinal liquid, medicinal liquid is cooled to 50 ℃～60 ℃, directly takes medicinal liquid and gets final product.

Claims

1. medicine for the treatment of nephritis, it is characterized in that: according to listed as parts by weight, it is prepared from for 13～28 parts by 15～30 parts of Herba Lysimachiaes, 10～25 parts of Radix Sophorae Tonkinensiss, 15～25 parts of Spora Lygodii, Radix Ginseng Rubra.

2. according to the medicine of the described treatment nephritis of claim 1, it is characterized in that: calculate according to weight, it is prepared from by Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g, Radix Ginseng Rubra 18g.

3. treat the preparation method of the medicine of nephritis according to claim 1, it is characterized in that: take by weighing medical material Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g and Radix Ginseng Rubra 18g, chopping, put into the chicken tripe of wash clean, chicken is put into pot, steaming and decocting 10～40 minutes, chicken cook the directly edible Carnis Gallus domesticus in back and get final product.

4. treat the preparation method of the medicine of nephritis according to claim 1, it is characterized in that: take by weighing medical material Herba Lysimachiae 25g, Radix Sophorae Tonkinensis 15g, Spora Lygodii 20g and Radix Ginseng Rubra 18g, the decocting that adds 2～5 times of medical material amounts boils 1～3 time, each 0.5～2 hour, merge medicinal liquid, medicinal liquid is cooled to 50 ℃～60 ℃, directly takes medicinal liquid and gets final product.