CN1833615A

CN1833615A - Highly visible cartridge having improved retainer

Info

Publication number: CN1833615A
Application number: CNA2005101301280A
Authority: CN
Inventors: 丹尼尔·L·肯尼迪
Original assignee: Pilling Weck Inc
Current assignee: Teleflex Medical Inc
Priority date: 2004-12-10
Filing date: 2005-12-12
Publication date: 2006-09-20
Anticipated expiration: 2025-12-12
Also published as: AU2005242190A1; CN100475164C; BRPI0506307A; JP2006175225A; US20060124485A1; HK1095722A1; CA2529080A1; KR20060093001A

Abstract

A substantially translucent cartridge is provided for retaining surgical clips, such as those used in surgical ligating procedures. The cartridge includes a polymeric composition base and a separable polymeric composition clip retainer supported by the base wherein the polymeric composition of the base and retainer includes a particulate, light diffusing material for imparting a substantially translucent optical effect for rendering, surgical clips visible within the cartridge. The polymeric composition may further include a radiopaque additive for rendering the cartridge imageable during radiographing.

Description

The visual enhanced grip box that improves keeper that has

Related application

The serial number that the application requires December in 2004 to submit in 10th is No.60/635, the benefit of 361 U.S. Provisional Patent Application, being disclosed in this and all being incorporated herein by reference of this application.

Technical field

Generally speaking, the application's theme relates to depositing and taking out of clip, specifically, relates to and is ready for use on the ligation clip of using such as the surgical operation in the surgical procedures such as hemostasis.More particularly, the present invention relates to a kind of visual enhanced grip box (cartridge) that is suitable for keeping clip in improved mode.

Background technology

In surgical procedures, many surgical procedure all need the blood vessel of human body or other tissue are carried out ligation.For example, many surgical procedure need be cut off blood vessel (as: vein or tremulous pulse), and these blood vessels may need ligation, and are hemorrhage to reduce.In some cases, the surgeon may wish in surgical procedures to trickle to the blood of operative site with minimizing temporarily with vascular ligation.In other cases, the surgeon may wish the permanent ligation of blood vessel.Can be by using the closed blood vessel of ligation clip, perhaps by using surgical thread to sew up the ligation that blood vessel is realized blood vessel or other tissue.Use the surgical thread ligation to need complicated pin operation, and need suture material to form the required knot of closed blood vessel.Such complex operations is comparatively consuming time and be difficult to execution, is being in the endoscopic procedures of characteristics with limited space and visuality especially.Comparatively speaking, ligation clip implements then relatively easy and quick.Therefore, ligation clip obtains a large amount of uses gradually in endoscope and wound operation.

Various types of hemostatic clamps and aneurysm clamp are used to ligation blood vessel or other tissue in surgical operation, to stop blood flow.This clip also is used in specially such as in the surgical operations such as sterillization process, with blocking-up or obstruction conduit and blood vessel.Usually, be generally known as the special mechanical device of operation applicator (surgical clipapplier), ligation applicator or hemostasis applicator, clip is applied to blood vessel or other tissue by use.And clip is just for good and all stayed there after being applied to this tissue.

Ligation clip can be classified according to its geometry (as: symmetry folder or asymmetric folder) and manufactured materials (as: metal clip or polymer folder) thereof.The symmetry folder is generally " C ", " U " or " V " shape, and so symmetrical substantially about the center longitudinal axis that extends between two branches of clip.The symmetry folder is usually by constituting such as rustless steel, titanium, tantalum or their alloy.Returning the example that discloses this clip in all U.S. Patent No.s 5,509,920 such as Philip.By using special applicator, permanent deformation on the metal clip blood vessel.Asymmetric folder then is made of polymeric material usually.

Because the clip of described type was smaller just now, and in surgical procedures, often use several clips, therefore at clip manufactured and/or package and finally be used between the operation process during this period of time in, adopt the clip stowage arrangement to deposit and keep a plurality of clips.A large amount of grip boxs are developed, and some of them are devoted to prevent that clip from unclamping inadequately in transportation with during handling or even displacement fully.Grip box is designed to use by " manually " applicator.

As used herein, such applicator represented in term " automatically ", and this kind applicator can keep a plurality of hemostatic clamps near the applicator jaw, can be bent at previous clip to make new clip be passed to jaw automatically after putting in place.Can distribute the example of a plurality of clips returning to disclose in all U.S. Patent No.s 4,509,518 such as McGarry for the applicator that uses in order.

Comparatively speaking, such applicator then represented in term " manually ", and this kind applicator once only holds a clip between two jaws, and after previous clip is bent, must manually reload clip.These manual instruments are designed to the tweezers type usually, and the operation of reloading generally inserts in clip storage or the grip box by the jaw with applicator, mesh then or the clip catching wherein to be comprised is finished.The jaw of applicator generally has in order to holding the ramose cannelure of clip, and can have end barrier (end-dam) at the far-end of each groove, with the tip motion of restriction clip.Because ramose natural elasticity of clip and end barrier if they exist, and are fixed in the jaw clip.Returning the example that discloses tweezers type applicator in all U.S. Patent No.s of Wood 3,326,216, having and be used between deformation phases clamping and the isogonism jaw of retaining clip subqueue.

The grip box of available many types all comprises a plurality of clip holding chambers that vertically separate at present.Single clip can leave in each folder chamber in several ways, and can from the folder chamber, remove by tweezers type applicator, applicator is inserted into selected folder chamber and abundant fastening clamp, overcoming employed any clip retention apparatus, thereby clip is removed from the folder chamber.

Known many kinds make clip remain on mechanism in the folder chamber of grip box.In all examples, the desirable target of this grip box is: make pack into applicator and subsequently it is removed required power minimum from grip box of clip, guarantee that simultaneously clip is installed in grip box and the safety in the applicator jaw subsequently is the highest before using.With regard to metal clip, the friction between clip and the single chamber sidewall thereof is enough to keep this clip usually.Grip box is generally made by injection plastic, so that each folder locular wall has some elasticity, and can push open each other when getting clip in the jaw insertion folder chamber of applicator.The example that keeps the grip box of clip in its folder chamber separately by the friction engagement with each folder chamber sidewall has been shown returning in all U.S. Patent No.s 4,076,120 such as Carroll.

In some grip boxs of the prior art that designs at metal clip, general each independent folder chamber all provides the newel that meets the clamp aperture shape, although can be big a little, when being pulled on this newel with convenient clip, by the CONTACT WITH FRICTION between clip branch and this newel, clip is remained in its folder chamber.In U.S. Patent No. 3,270, such grip box has been shown in 745, No.3,326,216, No.3,363,628, No.3,439,522 and No.3,439,523, all these patents all are awarded to Wood.

Also know the grip box of some prior aries, by pressure each clip is remained in its folder chamber, by folder in the chamber newel and the interaction between the clip middle part, and stretch into projection each folder chamber, and make clip keep local straight configuration towards newel (from end).Upwards push away by the bonding part, center of newel, and push away downwards, thereby clip is kept by the end of this projection with clip with clip.Return all U.S. Patent No.s 3,713,533 such as Reimels and return in all U.S. Patent No.s 4,146,130 such as Samuels such grip box has been shown.

Return all U.S. Patent No.s of Samuels 4,146,130 also to disclose the grip box of another kind of type, this kind grip box has from the sidewall of each folder chamber and stretches to a plurality of ribs of clip inwardly, thereby keeps clip by the friction engagement with these ribs.The above-mentioned all U.S. Patent No.s 4,146,130 such as Samuels of returning also show another kind of alternate embodiment, and this embodiment does not loosely remain on situation in grip box there being the friction engagement between clip and the folder chamber with clip at wanting.In this case, clip remains in each grip box by band, and this band can easily be cut off by applicator.

Although by using these grip boxs that are used for the prior art of metal clip and polymer folder to produce enough good effect, the composition of these grip boxs and structural design also exist some to limit the shortcoming of its function during use.

At first, because the surgical operation that is comprised in the grip box is smaller with the size of clip, and the grip box material of prior art is through visible light, therefore, the past surgeon is difficult to accurately judge and remains with how many clips in grip box, especially under the light condition of current Surgical Operating Room.Therefore, provide a kind of surgeon of making only just can judge the improvement grip box of the quantity of institute's reservation clip in the grip box rapidly with without benefits by the visual assessment box body.

The second, the same with any small-sized surgery instrument that in operation process, uses, there is grip box unexpected probability that is retained in there in the patient's body lumen of falling in operation process.Therefore, provide a kind of improved grip box, can pass through the ray technology imaging, thereby can easily detect the grip box of leaving in patient's body lumen, this will be very useful.

At last, the structure of the keeper mechanism of the grip box of many prior aries only is designed to serve as the localizer of clip between transportation and operation standby period.Collide if grip box falls or is subjected to other, and these keepers do not play a role well, will cause clip to break away from grip box prematurely.Therefore, it will be very favourable that the improvement grip box of the new structural design of a kind of combination is provided, and the design of this new construction not only can be used for the static clip that keeps, and if grip box be collided and can also serve as attenuator, with dynamic maintenance clip.

Summary of the invention

According to one embodiment of present invention, a kind of grip box of substantial transparent, the a plurality of clips that are used to keep the surgical operation of the biology coexistence that forms by suitable materials such as comprising metal and component of polymer to use, each clip has a pair of branch of stretching out from the abutment, to form symmetric substantially shape and to be suitable for being removed from this grip box by applicator.The grip box of this substantial transparent comprises: the clip retention of the matrix of component of polymer and the separable component of polymer that supported by this matrix; Wherein, the component of polymer of this matrix and keeper comprises the microgranule diffusion material, is used to produce the optical effect of substantially transparent, thus make clip that surgical operation uses in grip box as seen.This component of polymer selectively comprises radiopaque additive, so that the imaging during roentgenization of this grip box.This matrix has the matrix longitudinal axis, and comprise: a plurality of along this matrix extension and by the axially spaced wall of laterally placing with respect to base shaft, these walls limit a plurality of axially spaced folders chamber between any two at it, and wherein each folder chamber comprises first opening and second opening that side direction is relative; This matrix further comprises: a plurality of clips engage support component, and each clip joint support component places folder chamber separately, and are suitable for preventing that by supporting this clip at contiguous its junction point this surgical operation from moving down with clip; This clip retention comprises: a plurality of first and second relative elasticity contact pin are right, wherein each elasticity contact pin from the proximal extension that is fixed to this clip retention to the free distal end that stretches into by the respective side opening the corresponding folder chamber.In addition, each elasticity contact pin is being with slotted far-end to stop, and this groove has the side from its outwardly directed bifurcated.

According to another embodiment of the invention, a kind of grip box that is used to hold a plurality of surgical operations usefulness clips, each clip has a pair of branch of stretching out from the abutment, to form the shape of substantial symmetry, and be suitable for from this grip box, being removed by applicator, this grip box comprises: the matrix of component of polymer and the clip retention of separable component of polymer, this component of polymer selectively comprises radiopaque additive, so that this grip box imaging during roentgenization, perhaps selectively comprise the microgranule diffusion material, be used for making surgical operation at grip box as seen with clip.This matrix has the matrix longitudinal axis, and comprise: a plurality of along this matrix extension and by the axially spaced wall of laterally placing with respect to base shaft, these walls limit a plurality of axially spaced folders chamber between any two at it, and wherein each folder chamber comprises first opening and second opening that side direction is relative.This matrix comprises that further a plurality of clips engage support component, and each clip joint support component places folder chamber separately, and is suitable for preventing that by supporting this clip at contiguous its junction point this surgical operation from moving down with clip.This clip retention comprises that a plurality of first and second relative elasticity contact pin are right, wherein each elasticity contact pin from the proximal extension that is fixed to this clip retention to the free distal end that stretches into by the respective side opening the corresponding folder chamber.In addition, each elasticity contact pin is being with slotted far-end to stop, and this groove has the side from its outwardly directed bifurcated; And further comprise between the side of bifurcated, and inwards towards the slit of the proximal extension of this elasticity contact pin.

According to a further aspect in the invention, provide a kind of being used for to pack selected surgical operation into surgical operation with the method for applicator with clip.Preferably, this clip comprises: first branch, second branch and be connected this first branch and the second ramose abutment.This applicator preferably includes a pair of relative and first branch and the second ramose jaw that be suitable for meshing described clip.According to this method, the grip box of substantially transparent is provided, this grip box comprises: the matrix of component of polymer and the clip retention of separable component of polymer, wherein the component of polymer of this matrix and keeper comprises the microgranule diffusion material, producing the optical effect of substantially transparent, thus make surgical operation with clip in grip box as seen.The component of polymer of this matrix and keeper selectively comprises radiopaque additive, so that the imaging during roentgenization of this grip box.This method further comprises: watch this grip box, to determine the position of clip in the grip box; Then applicator is inserted in the folder chamber of from a plurality of folders chamber, selecting, to mesh selected clip.At this moment, from this grip box, remove selected clip.

Therefore, the object of the present invention is to provide a kind of grip box that strengthens visuality and be suitable for keeping in improved mode clip, this clip has a pair of branch of stretching out from the abutment, with the symmetric substantially shape of formation, and is suitable for being removed from this grip box by applicator.

Purpose and other purpose of the invention described above that illustrates in whole or in part by the present invention will be along with become clear below in conjunction with the detailed description of accompanying drawing.

Description of drawings

Fig. 1 is the perspective view of an example that is suitable for the clip of a plurality of basic symmetric shapes of being used in combination with grip box of the present invention;

Fig. 2 is according to the perspective view with assembling grip box of a plurality of clips that are loaded into wherein provided by the invention;

Fig. 3 is the decomposition diagram of grip box shown in Fig. 2;

The enlarged perspective of the clip retention contact pin that provides at grip box shown in Fig. 2 is provided Fig. 4;

Fig. 5 is the perspective view according to grip box provided by the invention, illustrates in the folder chamber that is inserted into this grip box and applicator that the clip indoor with being loaded in one of them folder is meshed; And

Fig. 6 is another perspective view of grip box shown in Fig. 5, illustrates by the clip that takes out from the folder chamber of this grip box.

The specific embodiment

Referring now to Fig. 1,, the example of a kind of symmetric substantially surgical operation with clip is described, this clip generally indicates that with 100 it is suitable for combining use with grip box described herein.Clip 100 and other similar design quilt are specially as can be closed around blood vessel or other types of tissue, and with the ligation blood vessel, thereby the hemostatic clamp of the liquid of blood vessel is flow through in prevention or minimizing.Clip 100 can be made of any suitable biology coexistence material, comprises certain metal and component of polymer (polymeric component).Clip 100 is symmetry substantially, and is generally " C ", " U " or " V " shape.The main body of clip 100 comprises that

first branch

102 and 104, the first branches 102 of second branch are connected by whole bonding part 106 at its near-end with second branch 104.

Referring now to Fig. 2,, according to the preferred embodiment that the invention provides the grip box that assembles, this grip box is identified generally as 200.Will describe in detail in a step as following, grip box 200 is designed to have a plurality of essentially identical folders chamber, and each folder chamber is suitable for depositing a clip 100, and this clip 100 preferably has the symmetric substantially design shown in as described above and Fig. 1.Fig. 2 illustrates the grip box 200 of present embodiment, is suitable for depositing six clips 100, and other embodiment that can deposit more or less clip 100 also can be provided certainly.If desired, can provide bonding backing (not shown), so that during use grip box 200 is fastened on chassis or other support component at the downside of grip box 200.

Will carry out structrual description in more detail with reference to Fig. 2 and Fig. 3 as following, grip box 200 comprises: generally with 210 body portions that identify, and generally with the 250 separable clip holding elements that identify.Preferably, matrix 210 and keeper 250 are made of component of polymer.This component of polymer can comprise: polypropylene, nylon, polyethylene terephthalate (polyethylene terephthalate, PET), polybutylene terephthalate (polybutylene terephthalate, PBT), polyformaldehyde and acronitrile-butadiene-styrene (acrylonitrile butadiene styrene, ABS) or the composition that those skilled in the art knew of other kind.

For provide can make the surgeon by the visual assessment box body, can judge the improvement grip box of the quantity of institute's reservation clip in the box rapidly, an embodiment of grip box 200 of the present invention is designed to substantially transparent.The optical effect of the substantially transparent that provides for grip box 200 according to the present invention, by very small amount of average maximum particle size is about 0.1 to 200 micron astigmatic particle with in casting and the thermoplastic polymer before pushing this mixture mix and realize.The amount of this microgranule diffusion material can be composition mixture weight 0.01% to 15%.The astigmatism particle can be any form, for example: the mixture of powder, fiber, palpus crystalline substance, thin layer platelet, thin slice, assembly, condensation product or these materials etc.Suitable particle includes but not limited to the calcium carbonate that nature forms, and this calcium carbonate can comprise: other calcium carbonate of reactant level, ground Chalk, ground limestone, ground marble and ground dolomite; Ground or fiber calcium sulfate; Such as silicate such as glass fibre, glass flake, entity and hollow glass ball, aluminium silicate, synthetic calcium silicate and Zirconium orthosilicate .s; Talcum; China clay; Splitting, thin layer platelet and Margarita; The nature Silicon stone is such as sand, quartz, quartzite, perlite and kieselguhr etc.; The fuming Silicon stone; Titanate is such as Barium metatitanate.; Sulfate is such as barium sulfate; Sulfide is such as zinc sulfide and molybdenum sulfide hydrochlorate; Metal-oxide is such as aluminium oxide, zinc oxide, beryllium oxide, magnesium oxide, zirconium oxide, stibium oxide, titanium dioxide and aluminium hydroxide and aluminium diboride thin slice etc.; Inorfil is such as wollastonite, basalt, boron, boron nitride and pottery etc.; Mono-crystlling fibre (as: must be brilliant) is such as those Alumina hydrates; Short fiber has the aluminum sulfate and the calcium sulfate hemihydrate (calcium sulfatehemihydrate) of magnalium oxide such as those; Organic smooth agent is such as wood powder and slurry; And any aforesaid mixture.

And not hard to imagine, can pass through the ray technology imaging in order to make grip box 200, so that can easily detect the whereabouts of the grip box of losing unintentionally in patient's body lumen 200, grip box 200 of the present invention can comprise radiopaque additive.This radiopaque additive preferably occupies about amount of 1.0% to 5.0% in component of polymer, and this radiopaque additive can comprise ceramic material, such as tungsten carbide or tungsten boride; Metallurgical material, such as metal (for example, platinum, titanium, iridium, tungsten, rhenium, gold and rustless steel), conductive ink or such as heavy metallic salts such as barium sulfate; Or its chemical compound; Also can use other material.Most preferably, this radiopaque additive is a barium sulfate, occupies weight and is about 2.0% amount.

The structure of grip box 200 is described now with reference to Fig. 3.Grip box 200 comprises: body portion 210, in order to reduce the amount of required composition material, in the manufacture process of this grip box 200, this body portion 210 can be included in the matrix groove 212 of base shaft formation longitudinally in the body portion 210.First axial end wall 214 and second axial end wall 215 and the first side wall 216 and second sidewall 217 extend around the substrate 218 of body portion 210 upward.Pillar 219 extends upward from substrate 218, so that clip holding element 250 to be described in detail below is installed.Will be clear from following description, the structure of grip box 200 can make symmetrical clip 100 pack into along a direction, and all clips 100 are all packed into same direction.Therefore, as shown in Figure 3, when leaving in clip 100 in the grip box 200, first branch 102 and second branch 104 of each clip 100 all always extend in this grip box 200 with downward direction.

Further referring to Fig. 3, a plurality of lateral arrangement and the folder locular wall 222 that separates vertically extend upward from substrate 218, and separate along the base shaft BA of grip box 200.Two transverse walls of that of the axle head of the most close grip box 200 (for example: at first transverse wall shown in the specific examples and the 7th transverse wall) are designated outermost transverse wall 222A and 222B respectively.Every pair of adjacent transverse wall that separates 222 (comprising outermost transverse wall 222A and 222B) limits folder chamber 226 separately betwixt.As shown in Figure 3, each transverse wall 222 is basically about base shaft BA symmetry, and each transverse wall 222 can outwards be tapered from base shaft BA, with quality that reduces grip box and the accessibility that improves clip 100.

Further referring to Fig. 3, each transverse wall 222 comprises a pair of relative horizontal wall that limits each folder chamber 226.For simplicity, the wall towards the rear among Fig. 3 is identified as 223A, and those walls towards the place ahead are identified as 223B.For the wall 223A that limits 226, one transverse walls 222 in given folder chamber towards the rear of body portion 210, and the wall 223B of next adjacent backward transverse wall 222 is forward towards the place ahead of body portion 210.Relative horizontal wall 223A, the 223B relevant with each folder chamber 226 limit a pair of side opening, are identified generally as 228A and 228B, enter into an opening of each side with the base shaft BA that is defined in grip box 200.As described below, the part of clip holding element 250 puts in each folder chamber 226 by this side opening 228A and 228B.

Further referring to Fig. 3, each folder chamber 226 of grip box 200 comprises the clip support component 232 of saddle type or cylindricality, with by the position prop clip 100 at contiguous its abutment 106, prevents that clip 100 from moving downward.Each clip support component 232 preferably forms between the middle part of relative lateral wall 222 along base shaft BA.Clip support component 232 preferably stretches out from substrate 218.In addition, clip support component 232 can connect between adjacent transverse wall 222 under the situation that does not have substrate 218 to support, and perhaps clip support component 232 can be not attached to contiguous transverse wall 222 by substrate 218 supports.

Referring now to Fig. 3 and Fig. 4,, grip box 200 further comprises separable clip holding element 250.This clip holding element 250 comprises box-like frame structure, and this structure comprises keeper bottom (retainerfloor) 252 and end wall 253A, 253B and sidewall 254A, 254B.Preferably on each angle of bottom 252, form opening 255, be used to hold the pillar 219 of corresponding grip box matrix 210, and be installed on this grip box matrix 210.

A series of relative jerk-fingers or elasticity contact pin are connected to sidewall 254A, 254B at near-end 262A ', 262B ' respectively to 262A, 262B, and with its far-end 262A ", 262B " extend mutually inwards respectively.Every couple of

elasticity contact pin

262A, 262B separate along longitudinal axis and adjacent elasticity contact pin 262A, the 262B of clip holding element 250.Preferably, each elasticity contact pin far-end 262A ", 262B " all comprise groove, be identified generally as the G (see figure 4), this groove has from it outwards towards elasticity contact pin far-end 262A ", 262B " side G1, the G2 of the bifurcated that extends of outermost point.In another embodiment of the present invention, elasticity contact pin far-end 262A ", 262B " further comprise slit, be identified generally as S, this slit S extends towards contact pin near-end 262A ', 262B ' inwards.Slit S serves as attenuator, and wherein side G1, the G2 of the bifurcated of groove G can remain on the fixed position with clip 100 statically in normal use with between the delivery period, and this slit S then can absorb the energy that clip 100 collisions are produced.Previously owing to grip box 200 falls or other stimulation causes clip 100 by the situation of improper release (referring to grip box of the prior art) under, slit S makes the clip 100 in the grip box 200 have the better dynamic retentivity.

As shown in Figures 2 and 3, before sealing and packing grip box 200, in case clip 100 is loaded in separately the folder chamber 226, clip holding element 250 just is installed on the grip box matrix 210, and with these grip box matrix 210 engagements.For clip holding element 250 is fastened on the grip box matrix 210, each opening 255 all will be installed on the corresponding pillar 219 that protrudes upward from grip box substrate 218.In the installation site of clip holding element 250, every

butt strip

262A, 262B stretch into the folder chamber 226 of each correspondence from their pairing opposite side opening 228A, 228B.Bifurcated side G1, the G2 of the contact pin groove G of each

contact pin

262A, 262B contacts with second bifurcated 104 with first bifurcated 102 of clip 100 respectively.Like this, just can prevent improper move (the as discussed above extra shock absorption that by slit S provided) of clip 100 in folder chamber 226, this point is in the processing of packaged grip box 200 and most important between the delivery period.

Referring now to Fig. 5 and Fig. 6,, description can be seen clip 100 and the method that clip 100 is taken out from grip box 200.When the grip box of aforesaid substantially transparent at first was provided, the surgeon just can observe this grip box from any angle basically, and the quantity of the clip in definite grip box 200 100 and position.Representative 300 the manual tweezers type applicator that is identified generally as shown in the figure, this applicator is shown in the position of engagement clip 100 in the selected folder chamber 226.Applicator 300 has a pair of jaw 302,304 at its tip, and this has groove 306,308 respectively to jaw on its interior surface opposing, and has corresponding end barrier 310,320 respectively.Should be appreciated that in fact any applicator all is fit to use with grip box 200, grip box as long as it can the clip that this is special be packed into.Therefore, grip box provided by the invention described herein both can use with the applicator with end barrier, also can be with not holding the applicator of barrier to use.

Because the jaw 302,304 of applicator at first is incorporated in the folder chamber 226, therefore, the far-end 262A of

contact pin

262A, 262B ", 262B " can help the applicator on the clip 100 placed in the middle.When placing folder during chamber 226 fully, the end of jaw 302,304 barrier 310,312 will be by the branch 102,104 of clip, and owing to the intrinsic elasticity in the clip, the branch 102,104 of clip will put in the groove 306,308 a little.At last, in case jaw 302,304 successfully meshes the branch 102,104 of clip, jaw 302,304 will be extracted from the folder chamber with the clip 100 that is engaged on fully wherein, thereby clip 100 is removed from folder chamber 226, in the operation process that is ready for use on hope.

Only be appreciated that otherwise deviate from scope of the present invention, can change each details of the present invention.And top description just is intended to explanation, is not in order to limit the present invention, and protection scope of the present invention is limited by described claim subsequently.

Claims

1, a kind of grip box that is used to keep a plurality of surgical operations with the substantially transparent of clips, each clip has a pair of branch of stretching out from the abutment, forming symmetric substantially shape, and is suitable for being removed from this grip box by applicator, and the grip box of this substantially transparent comprises:

(a) matrix of component of polymer, this matrix has the matrix longitudinal axis and comprises:

(i) a plurality of these walls limit a plurality of axially spaced folders chamber between any two at it along this matrix extension and with respect to the horizontal axially spaced wall of placing of base shaft, and wherein each folder chamber comprises first opening and second opening that side direction is relative; And

(ii) a plurality of clips engage support components, and each clip engages support component and is placed in separately the folder chamber, and is suitable for preventing surgical operation moving down with clip by supporting this clip at contiguous its junction point;

(b) clip retention of component of polymer, this clip retention is supported by this matrix and comprises that a plurality of first and second relative elasticity contact pin are right, wherein each contact pin from the proximal extension that is fixed to this clip retention to the free distal end that extend into by corresponding side opening the corresponding folder chamber, and further, wherein each contact pin is being with slotted this far-end to stop, and this groove has the side from its outwardly directed bifurcated; And

(c) wherein the component of polymer of this matrix and keeper comprises the microgranule diffusion material, is used to produce the optical effect of substantially transparent, thus make surgical operation with clip in this grip box as seen.

2, grip box as claimed in claim 1, wherein the component of polymer of this matrix and keeper is selected from the group of being made up of polypropylene, nylon, polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyformaldehyde and acronitrile-butadiene-styrene (ABS).

3, grip box as claimed in claim 1, wherein this microgranule diffusion material occupies about amount of 0.01% to 15% on weight.

4, grip box as claimed in claim 3, wherein this microgranule diffusion material have about 0.1 micron to about 200 microns average maximum particle size.

5, grip box as claimed in claim 3, wherein this microgranule diffusion material is selected from the group of being made up of calcium sulfate, Talcum, sulfate, china clay, Silicon stone, splitting, thin layer platelet, Muscovitum Margarita, titanate, metal sulfate, metal carbonate, sulfide, metal-oxide, boride, wollastonite, basalt, boron, pottery, mono-crystlling fibre, boron nitride, calcium carbonate of forming naturally and composition thereof.

6, grip box as claimed in claim 1, wherein the component of polymer of this matrix and keeper further comprises radiopaque additive, this additive occupies about amount of 1.0% to 5.0% on weight, be used to make the imaging during roentgenization of this grip box.

7, grip box as claimed in claim 6, wherein this radiopaque additive is a barium sulfate.

8, grip box as claimed in claim 6, wherein this radiopaque additive occupies 2.0% amount on weight.

9, grip box as claimed in claim 1, wherein the contact pin far-end of each clip retention further comprise between the side of described bifurcated, and inwards towards the slit of the proximal extension of this contact pin.

10, grip box as claimed in claim 1 further comprises: be placed at least one of described folder chamber and by corresponding clip and engage the surgical operation clip that support component supports.

11, grip box as claimed in claim 10, wherein this surgical operation clip surgical operation clip that is metal.

12, grip box as claimed in claim 10, use with having a pair of tweezers type applicator that is used to hold the jaw of this clip, wherein each jaw has and is used to hold the ramose groove of clip, and this groove and distal end hinder adjacency, are used for limiting the distal movement of the clip branch end that is accommodated in this groove.

13, a kind of being used to held the grip box that a plurality of surgical operations are used clip, and each clip has a pair of branch of stretching out from the abutment, with the symmetric substantially shape of formation, and is suitable for being removed from this grip box by applicator, and this grip box comprises:

(ii) a plurality of clips engage support component, and each clip joint support component is arranged in folder chamber separately, and are suitable for preventing surgical operation moving down with clip by in contiguous its junction point prop clip;

(b) clip retention of separable component of polymer, this clip retention is supported by this matrix and comprises that a plurality of first and second relative elasticity contact pin are right, wherein each elasticity contact pin from the proximal extension that is fixed to this clip retention to the free distal end that extend into by corresponding side opening the corresponding folder chamber, and further, wherein each contact pin is being with slotted this far-end to stop, this groove has the side from its outwardly directed bifurcated, and further comprise between the side of described bifurcated, inwards towards the slit of the proximal extension of this contact pin.

14, grip box as claimed in claim 13, wherein the component of polymer of this matrix and keeper is selected from the group of forming by polypropylene, nylon, polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyformaldehyde and acronitrile-butadiene-styrene (ABS).

15, grip box as claimed in claim 13, wherein the component of polymer of this matrix and keeper further comprises radiopaque additive, this additive occupies about amount of 1.0% to 5.0% on weight, so that the imaging during roentgenization of this grip box.

16, grip box as claimed in claim 15, wherein this radiopaque additive is a barium sulfate.

17, grip box as claimed in claim 15, wherein this radiopaque additive occupies 2.0% amount on weight.

18, grip box as claimed in claim 15, wherein the component of polymer of this matrix and keeper further comprises the microgranule diffusion material, is used to produce the optical effect of substantially transparent, thereby make surgical operation with clip in this grip box as seen.

19, grip box as claimed in claim 18, wherein this microgranule diffusion material occupies about amount of 0.01% to 15% on weight.

20, grip box as claimed in claim 18, wherein this microgranule diffusion material has and is about 0.1 micron to the average maximum particle size that is about 200 microns.

21, grip box as claimed in claim 18, wherein this microgranule diffusion material is selected from the group of being made up of calcium sulfate, Talcum, sulfate, china clay, Silicon stone, splitting, thin layer platelet, Muscovitum Margarita, titanate, metal sulfate, metal carbonate, sulfide, metal-oxide, boride, wollastonite, basalt, boron, pottery, mono-crystlling fibre, boron nitride, calcium carbonate of forming naturally and composition thereof.

22, grip box as claimed in claim 13 further comprises: be placed at least one of described folder chamber and by corresponding clip and engage the surgical operation clip that support component supports.

23, grip box as claimed in claim 22, wherein this surgical operation clip surgical operation clip that is metal.

24, grip box as claimed in claim 13, use with having a pair of tweezers type applicator that is used to hold the jaw of this clip, each jaw has and is used to hold the ramose groove of clip, this groove and distal end hinder adjacency, are used for limiting the distal movement of the clip branch end that is accommodated in this groove.

25, a kind of being used for selected surgical operation with pack into the method for surgical operation applicator of clip, wherein this clip comprises first branch, second branch and is connected this first branch and the second ramose abutment, and wherein this applicator comprises first branch and the second ramose a pair of relative jaw that is suitable for meshing described clip, and this method may further comprise the steps:

(a) provide the grip box of substantially transparent, this grip box comprises:

(i) comprise that a plurality of folders chamber and a plurality of clip engage the matrix of the component of polymer of support component, each clip engages support component and is placed in the corresponding folder chamber, and is suitable for preventing moving down of clip by in contiguous its junction point prop clip;

The (ii) clip retention of the component of polymer that supports by this matrix, this clip retention comprises that a plurality of first and second relative elasticity contact pin are right, wherein each contact pin from the proximal extension that is fixed to this clip retention to the free distal end that extend into by corresponding side opening the corresponding folder chamber, and further, wherein each contact pin is being with slotted this far-end to stop, and this groove has the side from its outwardly directed bifurcated;

(ii) wherein the component of polymer of this matrix and keeper comprises the microgranule diffusion material, is used to produce the optical effect of substantially transparent, thus make surgical operation with clip in this grip box as seen;

(b) watch this grip box, to determine the position of clip described in the grip box;

(c) it is indoor applicator to be inserted into a folder of selecting from a plurality of folders chamber, to mesh selected clip; And

(d) from this grip box, remove this selected clip.

26, method as claimed in claim 25 comprises: provide between the bifurcated side of the contact pin groove of each elasticity contact pin, and inwards towards the slit of the proximal extension of this contact pin.

27, method as claimed in claim 25 comprises: radiopaque additive is provided to the component of polymer of this matrix and keeper, is used to make the imaging during roentgenization of this grip box.

28, method as claimed in claim 25 is included in the surgical operation of metal clip is provided in this grip box.