CN1817366A - Medicinal composition for treating rheumatosis and preparation thereof - Google Patents
Medicinal composition for treating rheumatosis and preparation thereof Download PDFInfo
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- CN1817366A CN1817366A CNA2005101175409A CN200510117540A CN1817366A CN 1817366 A CN1817366 A CN 1817366A CN A2005101175409 A CNA2005101175409 A CN A2005101175409A CN 200510117540 A CN200510117540 A CN 200510117540A CN 1817366 A CN1817366 A CN 1817366A
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Abstract
A Chinese medicine for treating rheumatic osteopathy is prepared from 64 Chinese-medicinal materials including notoginseng, yam, coptis root, earthworm, etc. Its preparing process is also disclosed.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of rheumatic osteopathia.
Background technology
Cervical vertebra pain, scapulohumeral periarthritis clinical manifestation be dizzy dizzy, neck sour expand, rotate unfavorable, with blurring of vision connect and pain in the lumbar region, arm painful difficult act, shoulder, arm, hands, refer to, acid, fiber crops, pain, the cause of disease is many loses void, the kidney generating marrow and dominating bone, the marrow sky of suffering from a deficiency of the kidney by kidney qi, insufficiency of vital energy and blood in addition, the heresy that wind and cold is wet is taken advantage of a weak point, and is condensed in neck, shoulder week, QI-blood circulation is not smooth, and general rule is not painful; Rheumatism and rheumatoid, arthritis, numb limbs and tense tendons, the waist hip has a pain in the leg, and clinical manifestation is whole body and joint migration pain, the arthroncus distortion, joint stuffiness is met the Changes in weather aggravation, and severe patient can not be walked with descending, the cause of disease is many by positive QI-insufficiency, wind, cold, wet three evil excessive due to the muscles and bones venation block; Hyperosteogeny, lumber disc herniation, femur head necrosis, clinical manifestation is the lumbar vertebra distortion, pain, femoral head, knee joint, carrying out property of femoribus internus pain, chance adds up heavily, it is limited to squat down, the cause of disease many by suffer from a deficiency of the kidney, insufficiency of vital energy and blood, wound, fatigue, rheumatism take advantage of a weak point malpractice or medicine, alcoholism etc.; The traumatic injury clinical manifestation is redness, heat, pain function limitation part is swollen aches, injury of the bone crackle, and comminuted fracture, the cause of disease is fallen from eminence, due to motorcycle bump etc. are injured; Mastalgia, malignant boil furunculosis, clinical manifestation are red, swollen, hot, painful; Due to the product of many, the delicious food pungent of the cause of disease, fire-toxin intenseness of heat by surfeit.
Technology contents
The object of the invention is to provide a kind of pharmaceutical composition that the treatment rheumatic osteopathia is had remarkable result.
Another purpose of the present invention is to provide a kind of preparation of drug combination method for the treatment of rheumatic osteopathia.
The present invention is achieved through the following technical solutions: choose crude drug
First group:
Semen Strychni 500-1500 weight portion
Second group:
Herba Typhonii gigantei 250-750 weight portion Radix Aconiti 200-600 weight portion Radix Aconiti Kusnezoffii 200-600 weight portion
Rhizoma Arisaematis 25-75 weight portion Radix Notoginseng 25-75 weight portion Rhizoma Curcumae Longae 10-30 weight portion
Radix Puerariae 15-45 weight portion Rhizoma Coptidis 10-30 weight portion Pheretima 10-30 weight portion
Dry maxima skin 10-30 weight portion Solenognathus 7-23 weight portion Hippocampus 15-45 weight portion
The Agkistrodon 25-75 weight portion Zaocys 25-75 weight portion Radix Angelicae Pubescentis 50-150 of Qiang weight portion
Galla Chinensis 15-45 weight portion Rhizoma Corydalis 15-45 weight portion eupolyphage sece steleophaga 10-30 weight portion
Corium elephatis 25-75 weight portion Scorpio 10-30 weight portion Scolopendra 7-23 weight portion
Squama Manis 10-30 weight portion Rhizoma Gastrodiae 15-45 weight portion Semen Momordicae 15-45 weight portion
Semen Ricini 15-45 weight portion
The 3rd group:
Herba Ephedrae 10-30 weight portion Radix Angelicae Dahuricae 10-30 weight portion Cortex Phellodendri 10-30 weight portion
Radix Scutellariae 10-30 weight portion Semen Pittospori Glabrati 10-30 weight portion Flos Lonicerae 25-75 weight portion
Fructus Forsythiae 15-45 weight portion Radix Aconiti Lateralis Preparata 10-30 weight portion Cortex Cinnamomi 15-45 weight portion
Spina Gleditsiae 10-30 weight portion Ramulus Cinnamomi 10-30 weight portion Radix Angelicae Sinensis 10-30 weight portion
Radix Paeoniae Rubra 10-30 weight portion Rhizoma Chuanxiong 10-30 weight portion Radix Et Rhizoma Rhei 15-45 weight portion
Radix Astragali 25-75 weight portion Semen Persicae 15-45 weight portion Flos Carthami 50-150 weight portion
Rhizoma Drynariae 25-75 weight portion Radix Arnebiae (Radix Lithospermi) 25-75 weight portion Radix Stemonae 15-45 weight portion
Plantula Papaveris 15-45 weight portion Herba Asari 10-30 weight portion
The 4th group:
Sanguis Draxonis 12-38 weight portion Realgar 15-45 weight portion Pyritum 50-150 weight portion
Calomelas 8-23 weight portion Hydrargyri Oxydum Rubrum 8-23 weight portion Cinnabaris 10-30 weight portion
Borneolum Syntheticum 25-75 weight portion catechu 15-45 weight portion Borax 25-75 weight portion
The crisp 7-23 weight portion of Olibanum 50-150 weight portion Myrrha 50-150 weight portion Cicadae
Colophonium 10-30 weight portion Flos Caryophylli 15-45 weight portion
The optimum ratio of pharmaceutical composition of the present invention is: choose crude drug
First group:
Semen Strychni 1000 weight portions
Second group:
Herba Typhonii gigantei 500 weight portion Radix Aconiti 400 weight portion Radix Aconiti Kusnezoffii 400 weight portions
Rhizoma Arisaematis 50 weight portion Radix Notoginseng 50 weight portion Rhizoma Curcumae Longaes 20 weight portions
Radix Puerariae 30 weight portion Rhizoma Coptidis 20 weight portion Pheretimas 20 weight portions
Dry maxima skin 20 weight portion Solenognathus 15 weight portion hippocampus 3s 0 weight portion
Agkistrodon 50 weight portion Zaocys 50 weight portion Qiang Radix Angelicae Pubescentis 100 weight portions
Galla Chinensis 30 weight portion Rhizoma Corydalis 30 weight portion eupolyphage sece steleophagas 20 weight portions
Corium elephatis 50 weight portion Scorpio 20 weight portion Scolopendras 15 weight portions
Squama Manis 20 weight portion Rhizoma Gastrodiaes 30 weight portion Semen Momordicaes 30 weight portions
Semen Ricini 30 weight portions
The 3rd group:
The Herba Ephedrae 20 weight portion Radixs Angelicae Dahuricae 20 weight portion Cortex Phellodendris 20 weight portions
Radix Scutellariae 20 weight portion Semen Pittospori Glabrati 20 weight portion Flos Loniceraes 50 weight portions
Fructus Forsythiae 30 weight portion Radix Aconiti Lateralis Preparatas 20 weight portion Cortex Cinnamomis 30 weight portions
Spina Gleditsiae 20 weight portion Ramulus Cinnamomi 20 weight portion Radix Angelicae Sinensis 20 weight portions
Radix Paeoniae Rubra 20 weight portion Rhizoma Chuanxiongs 20 weight portion Radix Et Rhizoma Rhei 30 weight portions
The Radix Astragali 50 weight portion Semen Persicaes 30 weight portion Flos Carthamis 100 weight portions
The Rhizoma Drynariae 50 weight portion Radix Arnebiae (Radix Lithospermi)s 50 weight portion Radixs Stemonae 30 weight portions
Plantula Papaveris 30 weight portion Herba Asaris 20 weight portions
The 4th group:
Sanguis Draxonis 25 weight portion Realgars 30 weight portion Pyritums 100 weight portions
Calomelas 15 weight portion Hydrargyri Oxydum Rubrum 15 weight portion Cinnabaris 20 weight portions
Borneolum Syntheticum 50 weight portion catechu 30 weight portion Borax 50 weight portions
Crisp 15 weight portions of Olibanum 100 weight portion Myrrhas 100 weight portion Cicadaes
Colophonium 20 weight portion Flos Caryophyllis 30 weight portions
Preparation of drug combination method of the present invention is following steps:
1, earlier first group of crude drug Semen Strychni soaked 5～9, section is dried, and soaks 2～4 with Oleum sesami 500～1500 weight portions, friedly emits white cigarette to medicine is withered, pulls Semen Strychni out, and medicine oil is singly deposited standby; Second group of crude drug soaked 2～4 with Oleum sesami 2000～6000 weight portions again, fried emit white cigarette to medicine is withered, pull medicinal residues out, medicine oil treats that cool slightly back is standby; The medicine oil of second group of crude drug is added the 3rd group of crude drug, fried emit white cigarette, pull medicinal residues out, first group of medicine oil is added mixing together to medicine is withered;
2, it is standby the 4th group of crude drug to be ground into fine powder;
3, following red: add red prodrug oil and need endure 5～7 hours, stir while enduring, the plaster blackness is by enduring, brightness is stirred again, endures to dripping into pearl, and a slice of not loosing is advisable, will be with high heat 3～5 minutes before the following pellet, make oily temperature reach 300～360 the degree, leave naked light immediately, with Plumbum preparatium 1000～3000 weight portions as in the dusting cover, one people holds the sieve springing, Plumbum preparatium evenly is sprinkling upon on the pasta, and another human waddy stirs rapidly, and the messenger drug edema over the face is not on pasta or be sunken to the bottom of a pan, pellet descended in 5～10 minutes, red and medicine oil at high temperature changes rapidly, the blackening retrogradation, otherwise stop stirring, can spray a little cold water when excessive, then oily foam treats to emit in the pot a large amount of blue or green cigarettes from falling, and white cigarette plays plaster and becomes;
4, the inspection plaster is tender always, gets a little plaster and puts in the cold water, and the sticking hands in cold back draws not filamentation, and is too tender, endures again, as if the bean dregs embrittlement is too old, can adds tender oil and endure, pinches to sticking, and pulling force is arranged, and deceiving bright again is appropriateness;
5, the plaster temperature stirs evenly the 4th group of powder adding when 70～90 spend;
6, releasing fire-toxin: plaster is poured in the cold water while hot, and the limit bevelling stirs water toward a direction, make plaster entry in bulk, soaks 5～7;
7, be shaped at last: plaster is pulled out from water, squeezed water purification, be rubbed into strip, add the plaster quilt and flatten.
The conventional adjuvant that pharmaceutical composition of the present invention adds is pharmaceutically made clinical acceptable forms, any as in powder, spray, ointment, emplastrum or the ointment.
Pharmaceutical composition of the present invention has detoxifcation, evacuation of pus, granulation promoting, dispel the wind by wet, dredge the meridian passage, blood circulation promoting and blood stasis dispelling, reunion of fractured tendons and bones, the effect that detumescence relieves the pain, to treatment cervical spondylosis, scapulohumeral periarthritis, fiery scrofula pimple, lymphoid tuberculosis, hyperosteogeny, prolapse of lumbar intervertebral disc, femur head necrosis, tenosynovitis and cyst, malignant boil treats that poison, nameless gall, acute mastitis, chilblain, burn and scald become that skin ulcer person, traumatic injury, waist hip have a pain in the leg, rheumatism and rheumatoid, arthritis, numb limbs and tense tendons, disease effect such as ice-cold are remarkable.
Following experimental example is used to further specify the present invention:
Pharmaceutical composition clinical observation 100 routine patients of the present invention, clinical report is as follows:
One, clinical data:
100 routine patients are the outpatient, wherein male's 54 examples, women's 46 examples, 74 years old the highest age, minimal ages 17 years old, 51 years old mean age; Course of disease maximum duration 10 years, the shortest time is three days.
The 1st group: cervical vertebra pain, scapulohumeral periarthritis patient's 10 examples.
Clinical manifestation: dizzy dizzy, neck is sour expand, rotate unfavorable, with blurring of vision connect and pain in the lumbar region, arm painful difficult act, shoulder, arm, hands, refer to, acid, fiber crops, pain, the cause of disease is many loses void, the kidney generating marrow and dominating bone, the marrow sky of suffering from a deficiency of the kidney by kidney qi, insufficiency of vital energy and blood in addition, the heresy that wind and cold is wet is taken advantage of a weak point, and is condensed in neck, shoulder week, QI-blood circulation is not smooth, and general rule is not painful.Control suitable the kidney warming, mend the strong marrow of bone, dispel the wind by wetting, stimulate the menstrual flow and network, detumescence relieves the pain.The invention plaster that loses money in a business changed in five days one, and 1 pastes and cures 4 examples, and 3 paste and cure 5 examples, and 2 paste and cure 1 example; Total effective rate 100%.
Model case: poplar * * woman 36 years old wholeheartedly closes people from village in township two, suffers from cervical spondylosis 4 years, successively breathing out medical university, and OILFIELDS GENEROL HOSPITAL IN DAGING is taken the photograph sheet and is made a definite diagnosis, and fails to respond to any medical treatment in many ways, and the invention plaster 1 that loses money in a business pastes, and two days take effect, and cure in 10th, recover normal.On October 15th, 2004, grand celebration television station interviewed specially, reported two days continuously.
The 2nd group: rheumatism and rheumatoid, arthritis, numb limbs and tense tendons, waist hip patient's 50 examples that have a pain in the leg:
Clinical manifestation, whole body and joint migration pain, the arthroncus distortion, joint stuffiness is met the Changes in weather aggravation, and severe patient can not be walked with descending.The cause of disease is many by positive QI-insufficiency, wind, cold, wet three evil excessive due to the muscles and bones venation block.Control suitable: remove wind by wet, blood circulation promoting and blood stasis dispelling, stimulate the menstrual flow and network, detumescence relieves the pain.The invention plaster that loses money in a business changed in five days one, and 1 pastes and cures 2 examples, pastes 2 and pastes produce effects 2 examples, pasted 8 and pasted and cure 10 examples, pasted 4 and pasted and cure 18 examples, pasted 12 and pasted and cure 12 examples, pasted 16 and pasted and cure 6 examples.Total effective rate 100%.
Model case, open * * lived the slow township of reining in of this county's white tone and suffer from rheumatoid more than a year, bilateral knee arthroncus, ankle joint cysts in male 27 years old, swollen painful can not the clenching fist of joint in the both hands middle finger, can not work, walk and walk lamely, the invention plaster 5 that loses money in a business pastes, pain is extenuated, paste 16 altogether and paste and heal, can take part in the work, recover normally.
The 3rd group: hyperosteogeny, lumber disc herniation, femur head necrosis, patient's 15 examples.
Clinical manifestation: the lumbar vertebra distortion, pain, femoral head, knee joint, carrying out property of femoribus internus pain is met and is added up heavily, and it is limited to squat down.The cause of disease many by suffer from a deficiency of the kidney, insufficiency of vital energy and blood, wound, fatigue, rheumatism take advantage of a weak point malpractice or medicine, alcoholism etc.; Control suitable: the kidney invigorating, QI invigorating are enriched blood, blood circulation promoting and blood stasis dispelling, and mass dissipating and swelling eliminating relieves the pain.The invention plaster that loses money in a business changed in five days one, and 20 paste and cure 1 example, paste 12 and paste produce effects 13 examples, paste 1 and paste invalid 1 example, total effective rate 93.4%, inefficiency 6.6%.
The 4th group: traumatic injury, patient's 15 examples:
Clinical manifestation: local swollen painful 10 examples of red and swollen, hot, pain function limitation, injury of the bone crackle 4 examples, comminuted fracture 1 example.The cause of disease is fallen from eminence, due to the motorcycle bump is injured.Control suitable: blood circulation promoting and blood stasis dispelling, reunion of fractured tendons and bones, detumescence relieves the pain.The invention plaster that loses money in a business changed in five days one, and 4 paste swollen painful 7 examples of ending that disappear, and paste 1 and paste swollen 2 examples that disappear of produce effects alleviation of pain, pasted 12 and pasted and cure 6 examples.Total effective rate 100%.
Model case: Lee * * woman lived this county in 38 years old and wholeheartedly closes the village in township three, and injured because of jumping the foundation ankle, swelling pain can not walk with descending, and the invention plaster 1 that loses money in a business pastes the swollen alleviation of pain that disappears, and can lean on ground rod under, subsides 4 subsides healing fully.
The 5th group: mastalgia, malignant boil furunculosis patient 10 examples.
Clinical manifestation: red, swollen, hot, painful.Due to the product of many, the delicious food pungent of the cause of disease, fire-toxin intenseness of heat by surfeit; Control suitable: pathogenic wind expelling heat, separate fire-toxin, row is swollen, detumescence, granulation promoting, relieve the pain.The invention plaster that loses money in a business changed in five days one, and 1 pastes and cures 1 example, pasted 4 and pasted and cure 8 examples, pasted 1 and pasted invalid 1 example, cure rate 93.4%, inefficiency 6.6%.
Model case: Yang Pingshun man 56 years old. live the wholeheartedly big Wu Mianjing in township village, this county.The last year back of the body is given birth to a carbuncle, and pain is lain awake all night, and the invention plaster 1 that loses money in a business pastes and ends poison next day bitterly and loose and heal.
Two, curative effect determinate standard:
Cure fully: clinical symptom disappearance, functional rehabilitation can normally be taken part in the work, and lives on one's own life.
Produce effects: clinical symptoms is most to disappear, and partial function recovers, slightly labor life;
Invalid: clinical symptoms does not change, and is still swollen painful.
Three, therapeutic outcome: 100 examples
Cure fully: 72 examples account for 72%
Produce effects: 26 examples account for 26%
Invalid: 2 examples account for 2%
Total effective rate 98%.
Four, model case:
1, Liu * *, man, 27 years old; live in this county Hu Ji Tu Mo town chauffeur; modern spring femoribus internus is given birth to a furuncle and phyma are squeezed 20 centimetres of broken whole body fevers, the enlargement of lymph node, local red and swollen diffusion diameter after drinking, pain unbearably; the chicken of the gilding cream of drawing out pus by applying a plaster to the affected part is invalid; dead point head born of the same parents Qusong sodium three days, and symptom still can not be controlled, and the invention plaster 2 that loses money in a business pastes; only brought down a fever pain the same day, swelled in three days to disappear and heal.
2, record * *, man, 43 years old, people from Zhaodong City.Bilateral femoral head necrosis in 98 years, amyotrophy were pasted for 2 courses of treatment and are ended bitterly, changed in five days one 20 days courses of treatment, and amyotrophy begins to recover, and cured in 2 years.
3, in * *, the man, 32 years old, Du Meng county rail man suffered from femur head necrosis, the invention plaster 1 that loses money in a business pastes, relieve the pain next day, continues and pasted 2 years, the work of having gone to work.
4, horse * *, the woman, 32 years old, live safety village, Ke Ertai township, this county village, suffer from scapulohumeral periarthritis, painful difficult act of arm, clothes vast stretch of wooded country chinkuning 18 boxes, rare label sheet 6 boxes of rheumatism are invalid, the invention plaster 6 that loses money in a business pastes and heals.
5, Liu * *, the woman, 22 years old, this county chimney village town Dang turtle people from village, rheumatism, pain in the lumbar region, clothes vast stretch of wooded country chinkuning 17 boxes still can not oneself stand up, the invention plaster 12 that loses money in a business pastes, and cures fully, can normally manage household affairs;
6, well * *, the woman, 40 years old, live this county and wholeheartedly close the village in township three, lower limb has crackle by the motorcycle bone of wounding, redness can not be walked, the invention plaster one that loses money in a business pastes swollen disappearing, 10 paste and heal.
7, Lee * *, the man, 17 years old, live wholeheartedly backer village behind the township, this county, suffer from rheumatism February in this year and lean on crutches, father carries on the back and seeks medical advice, the invention plaster 2 that loses money in a business pastes abandons cane down, 6 paste and cure so far criminal.
8, poplar * *, the woman, 66 years old, live Ke Ertai village, Ke Ertai township, this county, the forward foot in a step in 8 years allows milch cow step on wound, can not walk with descending, invention plaster 12 subsides that lose money in a business, healing fully.
9, Yan * *, the woman, 28 years old, live in this chimney village, county south of a town Yang Cun, suffer from puerperal acute mastitis (one-sided) swollen painful can not suckling, the invention plaster one that loses money in a business pastes swollen disappearing, pain is ended and is healed.
Following embodiment is used to further specify the present invention:
Embodiment 1:
First group:
Semen Strychni 1000g
Second group:
Herba Typhonii gigantei 500g Radix Aconiti 400g Radix Aconiti Kusnezoffii 400g Rhizoma Arisaematis 50g
Radix Notoginseng 50g Rhizoma Curcumae Longae 20g Radix Puerariae 30g Rhizoma Coptidis 20g
Pheretima 20g dry maxima skin 20g Solenognathus 15g hippocampus 3 0g
The Agkistrodon 50g Zaocys 50g Radix Angelicae Pubescentis 100g of Qiang Galla Chinensis 30g
Rhizoma Corydalis 30g eupolyphage sece steleophaga 20g Corium elephatis 50g Scorpio 20g
Scolopendra 15g Squama Manis 20g Rhizoma Gastrodiae 30g Semen Momordicae 30g
Semen Ricini 30g
The 3rd group:
Herba Ephedrae 20g Radix Angelicae Dahuricae 20g Cortex Phellodendri 20g Radix Scutellariae 20g
Semen Pittospori Glabrati 20g Flos Lonicerae 50g Fructus Forsythiae 30g Radix Aconiti Lateralis Preparata 20g
Cortex Cinnamomi 30g Spina Gleditsiae 20g Ramulus Cinnamomi 20g Radix Angelicae Sinensis 20g
Radix Paeoniae Rubra 20g Rhizoma Chuanxiong 20g Radix Et Rhizoma Rhei 30g Radix Astragali 50g
Semen Persicae 30g Flos Carthami 100g Rhizoma Drynariae 50g Radix Arnebiae (Radix Lithospermi) 50g
Radix Stemonae 30g Plantula Papaveris 30g Herba Asari 20g
The 4th group:
Sanguis Draxonis 25g Realgar 30g Pyritum 100g Calomelas 15g
Hydrargyri Oxydum Rubrum 15g Cinnabaris 20g Borneolum Syntheticum 50g catechu 30g
The crisp 15g of Borax 50g Olibanum 100g Myrrha 100g Cicadae
Colophonium 20g Flos Caryophylli 30g
1, earlier first group of crude drug Semen Strychni soaked 7, section is dried, and soaks 3 with Oleum sesami 1000g, friedly emits white cigarette to medicine is withered, pulls Semen Strychni out, and medicine oil is singly deposited standby; Second group of crude drug soaked 3 with Oleum sesami 4000g again, fried emit white cigarette to medicine is withered, pull medicinal residues out, medicine oil treats that cool slightly back is standby; The medicine oil of second group of crude drug is added the 3rd group of crude drug, fried emit white cigarette, pull medicinal residues out, first group of medicine oil is added mixing together to medicine is withered;
2, it is standby the 4th group of crude drug to be ground into fine powder;
3, following red: add red prodrug oil and need endure 5～7 hours, stir while enduring, the plaster blackness is by enduring, brightness is stirred again, endures to dripping into pearl, and a slice of not loosing is advisable, will be with high heat 3～5 minutes before the following pellet, make oily temperature reach 300～360 the degree, leave naked light immediately, with Plumbum preparatium 2000g as in the dusting cover, one people holds the sieve springing, Plumbum preparatium evenly is sprinkling upon on the pasta, and another human waddy stirs rapidly, and the messenger drug edema over the face is not on pasta or be sunken to the bottom of a pan, pellet descended in 5～10 minutes, red and medicine oil at high temperature changes rapidly, the blackening retrogradation, otherwise stop stirring, can spray a little cold water when excessive, then oily foam treats to emit in the pot a large amount of blue or green cigarettes from falling, and white cigarette plays plaster and becomes;
4, the inspection plaster is tender always, gets a little plaster and puts in the cold water, and the sticking hands in cold back draws not filamentation, and is too tender, endures again, as if the bean dregs embrittlement is too old, can adds tender oil and endure, pinches to sticking, and pulling force is arranged, and deceiving bright again is appropriateness;
5, the plaster temperature stirs evenly the 4th group of powder adding when 80 spend;
6, releasing fire-toxin: plaster is poured in the cold water while hot, and the limit bevelling stirs water toward a direction, make plaster entry in bulk, soaks 5～7;
7, be shaped at last: plaster is pulled out from water, squeezed water purification, be rubbed into strip, roll into a ball heavy 15g nahlock to add the plaster quilt and flatten.
8, the plaster time spent heat softening, the external application affected part; Changed in five days one, 20 days be a course of treatment or paste more till.
Embodiment 2:
First group:
Semen Strychni 700g
Second group:
Herba Typhonii gigantei 650g Radix Aconiti 300g Radix Aconiti Kusnezoffii 500g Rhizoma Arisaematis 35g
Radix Notoginseng 65g Rhizoma Curcumae Longae 15g Radix Puerariae 40g Rhizoma Coptidis 15g
Pheretima 25g dry maxima skin 15g Solenognathus 20g Hippocampus 20g
The Agkistrodon 65g Zaocys 35g Radix Angelicae Pubescentis 130g of Qiang Galla Chinensis 20g
Rhizoma Corydalis 40g eupolyphage sece steleophaga 15g Corium elephatis 65g Scorpio 15g
Scolopendra 20g Squama Manis 15g Rhizoma Gastrodiae 40g Semen Momordicae 20g
Semen Ricini 40g
The 3rd group:
Herba Ephedrae 15g Radix Angelicae Dahuricae 25g Cortex Phellodendri 15g Radix Scutellariae 25g
Semen Pittospori Glabrati 15g Flos Lonicerae 65g Fructus Forsythiae 20g Radix Aconiti Lateralis Preparata 25g
Cortex Cinnamomi 20g Spina Gleditsiae 25g Ramulus Cinnamomi 15g Radix Angelicae Sinensis 25g
Radix Paeoniae Rubra 15g Rhizoma Chuanxiong 25g Radix Et Rhizoma Rhei 20g Radix Astragali 65g
Semen Persicae 20g Flos Carthami 130g Rhizoma Drynariae 35g Radix Arnebiae (Radix Lithospermi) 65g
Radix Stemonae 20g Plantula Papaveris 40g Herba Asari 15g
The 4th group:
Sanguis Draxonis 30g Realgar 20g Pyritum 130g Calomelas 10
Hydrargyri Oxydum Rubrum 20g Cinnabaris 15g Borneolum Syntheticum 65g catechu 20g
The crisp 10g of Borax 65g Olibanum 70g Myrrha 130g Cicadae
Colophonium 30g Flos Caryophylli 20g
Above-mentioned raw materials medicine technology is routinely made powder.
Embodiment 3:
First group:
Semen Strychni 1300g
Second group:
Herba Typhonii gigantei 350g Radix Aconiti 500g Radix Aconiti Kusnezoffii 300g Rhizoma Arisaematis 65g
Radix Notoginseng 35g Rhizoma Curcumae Longae 25g Radix Puerariae 20g Rhizoma Coptidis 25g
Pheretima 15g Cutis Bufonis 25g Solenognathus 10g Hippocampus 40g
The Agkistrodon 35g Zaocys 65g Radix Angelicae Pubescentis 70g of Qiang Galla Chinensis 40g
Rhizoma Corydalis 20g eupolyphage sece steleophaga 25g Corium elephatis 35g Scorpio 25g
Scolopendra 10g Squama Manis 25g Rhizoma Gastrodiae 20g Semen Momordicae 40g
Semen Ricini 20g
The 3rd group:
Herba Ephedrae 25g Radix Angelicae Dahuricae 15g Cortex Phellodendri 25g Radix Scutellariae 15g
Semen Pittospori Glabrati 25g Flos Lonicerae 35g Fructus Forsythiae 40g Radix Aconiti Lateralis Preparata 15g
Cortex Cinnamomi 40g Spina Gleditsiae 15g Ramulus Cinnamomi 25g Radix Angelicae Sinensis 15g
Radix Paeoniae Rubra 25g Rhizoma Chuanxiong 15g Radix Et Rhizoma Rhei 40g Radix Astragali 35g
Semen Persicae 40g Flos Carthami 70g Rhizoma Drynariae 65g Radix Arnebiae (Radix Lithospermi) 35g
Radix Stemonae 40g Plantula Papaveris 20g Herba Asari 25g
The 4th group:
Sanguis Draxonis 20g Realgar 40g Pyritum 70g Calomelas 20g
Hydrargyri Oxydum Rubrum Zhu 10g * sand 25g Borneolum Syntheticum 35g catechu 40g
The crisp 20g of Borax 35g Olibanum 130g Myrrha 70g Cicadae
Colophonium 15g Flos Caryophylli 40g
Above-mentioned raw materials medicine technology is routinely made spray.
Claims (10)
1, a kind of pharmaceutical composition for the treatment of rheumatic osteopathia is characterized in that said composition made by following crude drug:
First group:
Semen Strychni 500-1500 weight portion
Second group:
Herba Typhonii gigantei 250-750 weight portion Radix Aconiti 200-600 weight portion Radix Aconiti Kusnezoffii 200-600 weight portion
Rhizoma Arisaematis 25-75 weight portion Radix Notoginseng 25-75 weight portion Rhizoma Curcumae Longae 10-30 weight portion
Radix Puerariae 15-45 weight portion Rhizoma Coptidis 10-30 weight portion Pheretima 10-30 weight portion
Dry maxima skin 10-30 weight portion Solenognathus 7-23 weight portion Hippocampus 15-45 weight portion
The Agkistrodon 25-75 weight portion Zaocys 25-75 weight portion Radix Angelicae Pubescentis 50-150 of Qiang weight portion
Galla Chinensis 15-45 weight portion Rhizoma Corydalis 15-45 weight portion eupolyphage sece steleophaga 10-30 weight portion
Corium elephatis 25-75 weight portion Scorpio 10-30 weight portion Scolopendra 7-23 weight portion
Squama Manis 10-30 weight portion Rhizoma Gastrodiae 15-45 weight portion Semen Momordicae 15-45 weight portion
Semen Ricini 15-45 weight portion
The 3rd group:
Herba Ephedrae 10-30 weight portion Radix Angelicae Dahuricae 10-30 weight portion Cortex Phellodendri 10-30 weight portion
Radix Scutellariae 10-30 weight portion Semen Pittospori Glabrati 10-30 weight portion Flos Lonicerae 25-75 weight portion
Fructus Forsythiae 15-45 weight portion Radix Aconiti Lateralis Preparata 10-30 weight portion Cortex Cinnamomi 15-45 weight portion
Spina Gleditsiae 10-30 weight portion Ramulus Cinnamomi 10-30 weight portion Radix Angelicae Sinensis 10-30 weight portion
Radix Paeoniae Rubra 10-30 weight portion Rhizoma Chuanxiong 10-30 weight portion Radix Et Rhizoma Rhei 15-45 weight portion
Radix Astragali 25-75 weight portion Semen Persicae 15-45 weight portion Flos Carthami 50-150 weight portion
Rhizoma Drynariae 25-75 weight portion Radix Arnebiae (Radix Lithospermi) 25-75 weight portion Radix Stemonae 15-45 weight portion
Plantula Papaveris 15-45 weight portion Herba Asari 10-30 weight portion
The 4th group:
Sanguis Draxonis 12-38 weight portion Realgar 15-45 weight portion Pyritum 50-150 weight portion
Calomelas 8-23 weight portion Hydrargyri Oxydum Rubrum 8-23 weight portion Cinnabaris 10-30 weight portion
Borneolum Syntheticum 25-75 weight portion catechu 15-45 weight portion Borax 25-75 weight portion
The crisp 7-23 weight portion of Olibanum 50-150 weight portion Myrrha 50-150 weight portion Cicadae
Colophonium 10-30 weight portion Flos Caryophylli 15-45 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
First group:
Semen Strychni 1000 weight portions
Second group:
Herba Typhonii gigantei 500 weight portion Radix Aconiti 400 weight portion Radix Aconiti Kusnezoffii 400 weight portions
Rhizoma Arisaematis 50 weight portion Radix Notoginseng 50 weight portion Rhizoma Curcumae Longaes 20 weight portions
Radix Puerariae 30 weight portion Rhizoma Coptidis 20 weight portion Pheretimas 20 weight portions
Dry maxima skin 20 weight portion Solenognathus 15 weight portion hippocampus 3s 0 weight portion
Agkistrodon 50 weight portion Zaocys 50 weight portion Qiang Radix Angelicae Pubescentis 100 weight portions
Galla Chinensis 30 weight portion Rhizoma Corydalis 30 weight portion eupolyphage sece steleophagas 20 weight portions
Corium elephatis 50 weight portion Scorpio 20 weight portion Scolopendras 15 weight portions
Squama Manis 20 weight portion Rhizoma Gastrodiaes 30 weight portion Semen Momordicaes 30 weight portions
Semen Ricini 30 weight portions
The 3rd group:
The Herba Ephedrae 20 weight portion Radixs Angelicae Dahuricae 20 weight portion Cortex Phellodendris 20 weight portions
Radix Scutellariae 20 weight portion Semen Pittospori Glabrati 20 weight portion Flos Loniceraes 50 weight portions
Fructus Forsythiae 30 weight portion Radix Aconiti Lateralis Preparatas 20 weight portion Cortex Cinnamomis 30 weight portions
Spina Gleditsiae 20 weight portion Ramulus Cinnamomi 20 weight portion Radix Angelicae Sinensis 20 weight portions
Radix Paeoniae Rubra 20 weight portion Rhizoma Chuanxiongs 20 weight portion Radix Et Rhizoma Rhei 30 weight portions
The Radix Astragali 50 weight portion Semen Persicaes 30 weight portion Flos Carthamis 100 weight portions
The Rhizoma Drynariae 50 weight portion Radix Arnebiae (Radix Lithospermi)s 50 weight portion Radixs Stemonae 30 weight portions
Plantula Papaveris 30 weight portion Herba Asaris 20 weight portions
The 4th group:
Sanguis Draxonis 25 weight portion Realgars 30 weight portion Pyritums 100 weight portions
Calomelas 15 weight portion Hydrargyri Oxydum Rubrum 15 weight portion Cinnabaris 20 weight portions
Borneolum Syntheticum 50 weight portion catechu 30 weight portion Borax 50 weight portions
Crisp 15 weight portions of Olibanum 100 weight portion Myrrhas 100 weight portion Cicadaes
Colophonium 20 weight portion Flos Caryophyllis 30 weight portions.
3, pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
First group:
Semen Strychni 700 weight portions
Second group:
Herba Typhonii gigantei 650 weight portion Radix Aconiti 300 weight portion Radix Aconiti Kusnezoffii 500 weight portions
Rhizoma Arisaematis 35 weight portion Radix Notoginseng 65 weight portion Rhizoma Curcumae Longaes 15 weight portions
Radix Puerariae 40 weight portion Rhizoma Coptidis 15 weight portion Pheretimas 25 weight portions
Dry maxima skin 15 weight portion Solenognathus 20 weight portion Hippocampus 20 weight portions
Agkistrodon 65 weight portion Zaocys 35 weight portion Qiang Radix Angelicae Pubescentis 130 weight portions
Galla Chinensis 20 weight portion Rhizoma Corydalis 40 weight portion eupolyphage sece steleophagas 15 weight portions
Corium elephatis 65 weight portion Scorpio 15 weight portion Scolopendras 20 weight portions
Squama Manis 15 weight portion Rhizoma Gastrodiaes 40 weight portion Semen Momordicaes 20 weight portions
Semen Ricini 40 weight portions
The 3rd group:
The Herba Ephedrae 15 weight portion Radixs Angelicae Dahuricae 25 weight portion Cortex Phellodendris 15 weight portions
Radix Scutellariae 25 weight portion Semen Pittospori Glabrati 15 weight portion Flos Loniceraes 65 weight portions
Fructus Forsythiae 20 weight portion Radix Aconiti Lateralis Preparatas 25 weight portion Cortex Cinnamomis 20 weight portions
Spina Gleditsiae 25 weight portion Ramulus Cinnamomi 15 weight portion Radix Angelicae Sinensis 25 weight portions
Radix Paeoniae Rubra 15 weight portion Rhizoma Chuanxiongs 25 weight portion Radix Et Rhizoma Rhei 20 weight portions
The Radix Astragali 65 weight portion Semen Persicaes 20 weight portion Flos Carthamis 130 weight portions
The Rhizoma Drynariae 35 weight portion Radix Arnebiae (Radix Lithospermi)s 65 weight portion Radixs Stemonae 20 weight portions
Plantula Papaveris 40 weight portion Herba Asaris 15 weight portions
The 4th group:
Sanguis Draxonis 30 weight portion Realgars 20 weight portion Pyritums 130 weight portions
Calomelas 10 weight portion Hydrargyri Oxydum Rubrum 20 weight portion Cinnabaris 15 weight portions
Borneolum Syntheticum 65 weight portion catechu 20 weight portion Borax 65 weight portions
Crisp 10 weight portions of Olibanum 70 weight portion Myrrhas 130 weight portion Cicadaes
Colophonium 30 weight portion Flos Caryophyllis 20 weight portions.
4, pharmaceutical composition according to claim 1 is characterized in that said composition made by following crude drug:
First group:
Semen Strychni 1300 weight portions
Second group:
Herba Typhonii gigantei 350 weight portion Radix Aconiti 500 weight portion Radix Aconiti Kusnezoffii 300 weight portions
Rhizoma Arisaematis 65 weight portion Radix Notoginseng 35 weight portion Rhizoma Curcumae Longaes 25 weight portions
Radix Puerariae 20 weight portion Rhizoma Coptidis 25 weight portion Pheretimas 15 weight portions
Dry maxima skin 25 weight portion Solenognathus 10 weight portion Hippocampus 40 weight portions
Agkistrodon 35 weight portion Zaocys 65 weight portion Qiang Radix Angelicae Pubescentis 70 weight portions
Galla Chinensis 40 weight portion Rhizoma Corydalis 20 weight portion eupolyphage sece steleophagas 25 weight portions
Corium elephatis 35 weight portion Scorpio 25 weight portion Scolopendras 10 weight portions
Squama Manis 25 weight portion Rhizoma Gastrodiaes 20 weight portion Semen Momordicaes 40 weight portions
Semen Ricini 20 weight portions
The 3rd group:
The Herba Ephedrae 25 weight portion Radixs Angelicae Dahuricae 15 weight portion Cortex Phellodendris 25 weight portions
Radix Scutellariae 15 weight portion Semen Pittospori Glabrati 25 weight portion Flos Loniceraes 35 weight portions
Fructus Forsythiae 40 weight portion Radix Aconiti Lateralis Preparatas 15 weight portion Cortex Cinnamomis 40 weight portions
Spina Gleditsiae 15 weight portion Ramulus Cinnamomi 25 weight portion Radix Angelicae Sinensis 15 weight portions
Radix Paeoniae Rubra 25 weight portion Rhizoma Chuanxiongs 15 weight portion Radix Et Rhizoma Rhei 40 weight portions
The Radix Astragali 35 weight portion Semen Persicaes 40 weight portion Flos Carthamis 70 weight portions
The Rhizoma Drynariae 65 weight portion Radix Arnebiae (Radix Lithospermi)s 35 weight portion Radixs Stemonae 40 weight portions
Plantula Papaveris 20 weight portion Herba Asaris 25 weight portions
The 4th group:
Sanguis Draxonis 20 weight portion Realgars 40 weight portion Pyritums 70 weight portions
Calomelas 20 weight portion Hydrargyri Oxydum Rubrum 10 weight portion Cinnabaris 25 weight portions
Borneolum Syntheticum 35 weight portion catechu 40 weight portion Borax 35 weight portions
Crisp 20 weight portions of Olibanum 130 weight portion Myrrhas 70 weight portion Cicadaes
Colophonium 15 weight portion Flos Caryophyllis 40 weight portions.
5, according to the described pharmaceutical composition of one of claim 1-4, the preparation method that it is characterized in that said composition is following steps:
1), earlier first group of crude drug Semen Strychni soaked 5～9, section is dried, and soaks 2～4 with Oleum sesami 500～1500 weight portions, friedly emits white cigarette to medicine is withered, pulls Semen Strychni out, and medicine oil is singly deposited standby; Second group of crude drug soaked 2～4 with Oleum sesami 2000～6000 weight portions again, fried emit white cigarette to medicine is withered, pull medicinal residues out, medicine oil treats that cool slightly back is standby; The medicine oil of second group of crude drug is added the 3rd group of crude drug, fried emit white cigarette, pull medicinal residues out, first group of medicine oil is added mixing together to medicine is withered;
2) it is standby, the 4th group of crude drug to be ground into fine powder;
3), following red: add red prodrug oil and need endure 5～7 hours, stir while enduring, the plaster blackness is by enduring, brightness is stirred again, endures to dripping into pearl, and a slice of not loosing is advisable, will be with high heat 3～5 minutes before the following pellet, make oily temperature reach 300～360 the degree, leave naked light immediately, with Plumbum preparatium 1000-3000 weight portion as in the dusting cover, one people holds the sieve springing, Plumbum preparatium evenly is sprinkling upon on the pasta, and another human waddy stirs rapidly, and the messenger drug edema over the face is not on pasta or be sunken to the bottom of a pan, pellet descended in 5～10 minutes, red and medicine oil at high temperature changes rapidly, the blackening retrogradation, otherwise stop stirring, can spray a little cold water when excessive, then oily foam treats to emit in the pot a large amount of blue or green cigarettes from falling, and white cigarette plays plaster and becomes;
4), check that plaster is tender always, get a little plaster and put in the cold water, the sticking hands in cold back draws not filamentation, and is too tender, endures again, as if the bean dregs embrittlement is too old, can adds tender oil and endure, pinches to sticking, and pulling force is arranged, black bright again be appropriate;
5), the plaster temperature when 70～90 spend, the 4th group of powder added stir evenly;
6), releasing fire-toxin: plaster is poured in the cold water while hot, and the limit bevelling stirs water toward a direction, make plaster entry in bulk, soaks 5～7;
7) be shaped, at last: plaster is pulled out from water, squeezed water purification, be rubbed into strip, add the plaster quilt and flatten.
6, preparation of drug combination method according to claim 5 is characterized in that this method is following steps:
1), earlier first group of crude drug Semen Strychni soaked 7, section is dried, and soaks 3 with Oleum sesami 1000 weight portions, friedly emits white cigarette to medicine is withered, pulls Semen Strychni out, and medicine oil is singly deposited standby; Second group of crude drug soaked 3 with Oleum sesami 4000 weight portions again, fried emit white cigarette to medicine is withered, pull medicinal residues out, medicine oil treats that cool slightly back is standby; The medicine oil of second group of crude drug is added the 3rd group of crude drug, fried emit white cigarette, pull medicinal residues out, first group of medicine oil is added mixing together to medicine is withered;
2) it is standby, the 4th group of crude drug to be ground into fine powder;
3), following red: add red prodrug oil and need endure 5～7 hours, stir while enduring, the plaster blackness is by enduring, brightness is stirred again, endures to dripping into pearl, and a slice of not loosing is advisable, will be with high heat 3～5 minutes before the following pellet, make oily temperature reach 300～360 the degree, leave naked light immediately, with Plumbum preparatium 2000 weight portions as in the dusting cover, one people holds the sieve springing, Plumbum preparatium evenly is sprinkling upon on the pasta, and another human waddy stirs rapidly, and the messenger drug edema over the face is not on pasta or be sunken to the bottom of a pan, pellet descended in 5～10 minutes, red and medicine oil at high temperature changes rapidly, the blackening retrogradation, otherwise stop stirring, can spray a little cold water when excessive, then oily foam treats to emit in the pot a large amount of blue or green cigarettes from falling, and white cigarette plays plaster and becomes;
4), check that plaster is tender always, get a little plaster and put in the cold water, the sticking hands in cold back draws not filamentation, and is too tender, endures again, as if the bean dregs embrittlement is too old, can adds tender oil and endure, pinches to sticking, and pulling force is arranged, black bright again be appropriate;
5), the plaster temperature when 80 spend, the 4th group of powder added stir evenly;
6), releasing fire-toxin: plaster is poured in the cold water while hot, and the limit bevelling stirs water toward a direction, make plaster entry in bulk, soaks 5～7;
7) be shaped, at last: plaster is pulled out from water, squeezed water purification, be rubbed into strip, add the plaster quilt and flatten.
7,, it is characterized in that the conventional adjuvant that said composition adds pharmaceutically makes the dosage form of clinical acceptance according to the described pharmaceutical composition of one of claim 1-4.
8, pharmaceutical composition according to claim 7 is characterized in that described dosage form is any in powder, spray, ointment, emplastrum or the ointment.
9,, it is characterized in that said composition has a pain in the leg at preparation treatment rheumatism and rheumatoid arthritis, numb limbs and tense tendons, waist hip, the application in cervical spondylosis, scapulohumeral periarthritis, hyperosteogeny, prolapse of lumbar intervertebral disc, femur head necrosis or the traumatic injury medicine according to the described pharmaceutical composition of one of claim 1-4.
10,, it is characterized in that the application of said composition in preparation treatment mastalgia, malignant boil furunculosis, fiery scrofula pimple, lymphoid tuberculosis, chilblain or burn and scald medicine according to the described pharmaceutical composition of one of claim 1-4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005101175409A CN100441218C (en) | 2005-11-04 | 2005-11-04 | Medicinal composition for treating rheumatosis and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005101175409A CN100441218C (en) | 2005-11-04 | 2005-11-04 | Medicinal composition for treating rheumatosis and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1817366A true CN1817366A (en) | 2006-08-16 |
| CN100441218C CN100441218C (en) | 2008-12-10 |
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ID=36917695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005101175409A Expired - Fee Related CN100441218C (en) | 2005-11-04 | 2005-11-04 | Medicinal composition for treating rheumatosis and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100441218C (en) |
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| CN101199815B (en) * | 2006-12-13 | 2010-11-17 | 付佐华 | Medicament compound for treating rheumatism, rheumatoid arthritis |
| CN101284108B (en) * | 2008-03-20 | 2010-12-08 | 李俊海 | Traditional Chinese medicine combination for curing lumbar disease |
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