CN1763544B - Minisize detection tank for high performance liquid chromatography-electrochemical detection - Google Patents
Minisize detection tank for high performance liquid chromatography-electrochemical detection Download PDFInfo
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- CN1763544B CN1763544B CN 200510107437 CN200510107437A CN1763544B CN 1763544 B CN1763544 B CN 1763544B CN 200510107437 CN200510107437 CN 200510107437 CN 200510107437 A CN200510107437 A CN 200510107437A CN 1763544 B CN1763544 B CN 1763544B
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Abstract
The invention discloses a micro detection pool of highly effective liquid chromatograph-electrochemistry detection, which is characterized by the following: the sampling pipe (6) connects the micro detection pool through screw (7), which encases a sealing ring (5) to keep the sealing property of detection pool; the sample-out pipe (9) connects the micro detection pool through screw (10), which encases a sealing ring (8) to keep the sealing property of detection pool; the liquid bath (11) of 3 mm diameter is set between screw (7) and (10) within floating liquid, whose electrode is put in the floating liquid bath (11); the combination electrode interface (12) connects the mating combination electrode (4) through thread, which fixes the combination electrode (4) and keeps sealing property; (13) is pool body of micro detection pool.
Description
Technical field
The present invention relates to a kind of minisize detection tank that high performance liquid chromatography-electrochemical detects that is used for, belong to liquid chromatography-Electrochemical Detection analysis technical field.
Background technology
High performance liquid chromatography-electrochemical detects the method that is to use Electrochemical Detection and high performance liquid chromatography coupling, and the minisize detection tank that is used for the high performance liquid chromatography-electrochemical detection then is a kind of minisize detection tank of electrochemical detection system part.
High performance liquid chromatography itself can provide multicomponent analysis, and can eliminate Interference Peaks, more saves time more effective than other method.The detecting device of high performance liquid chromatography can be divided into according to the measuring principle difference: photoelectric detector, calorifics detecting device and electrochemical detector.Use the advantage of Electrochemical Detection to be: the sample preparation process is simple, does not need sample is carried out derivatization, and consumption is few, high specificity, and analysis time is short, and highly sensitive, accuracy is good.Generally speaking, the minisize detection tank that is used for Electrochemical Detection must use working electrode, contrast electrode, to three absolute electrodes of electrode, and three electrodes insert from three of minisize detection tank different sides respectively, make moving phase through three electrode cross section.Add injection port and outlet like this, have five mouths on each minisize detection tank at least.The shortcoming of this detection cell is a complex structure, and the minisize detection tank punching is too many, and sealing is poor, easy seepage, complicated operation during detection.
Summary of the invention
The purpose of this invention is to provide a kind of minisize detection tank that high performance liquid chromatography-electrochemical detects that is used for, it is simple in structure, and good seal performance can be avoided seepage greatly, and simple to operate when detecting.
The minisize detection tank (abbreviation minisize detection tank) that is used for the high performance liquid chromatography-electrochemical detection of the present invention.An injection port and an outlet and an electrode connection holes are arranged on the minisize detection tank, injection port and outlet point-blank, the electrode connection holes is vertical with this straight line; The compound electrode of Pei Heing is made up of electrode working electrode, filamentary silver contrast electrode and platinum filament with it, and successively around the periphery of working electrode, the three forms concentric circles to electrode for filamentary silver contrast electrode and platinum filament, and three electrodes form a whole with epoxy encapsulation.When moving phase is flowed through compound electrode simultaneously through three electrodes.
Minisize detection tank in the past has three electrode jacks, and minisize detection tank of the present invention only has an electrode connection holes, compares with minisize detection tank in the past, can significantly reduce solution and rush down the leakage phenomenon.What match with the present invention is a compound electrode, rather than three electrodes independently, makes that the assembling of detection cell is simple, simple and efficient to handle during detection; And working electrode and contrast electrode, certain to distance between electrodes, thus reduced since the difference of the relative distance between each electrode to the influence of analysis to measure.
Minisize detection tank of the present invention mainly is widely used in fields such as bioengineering and biological chemistry, medical research, food analysis, environmental analysis, fine chemistry industries.
Description of drawings
Fig. 1 be match with the present invention the synoptic diagram of compound electrode.
Fig. 2 is the structural representation of minisize detection tank of the present invention.This figure also is the specification digest accompanying drawing.
Come minisize detection tank of the present invention is made explanation further below by embodiment and embodiment.
Embodiment
Embodiment 1:
Minisize detection tank of the present invention is as shown in Figure 2: sample introduction pipe 6, link to each other with minisize detection tank with first screw 7, and cover first O-ring seal 5 is in order to guarantee the sealing property of detection cell on the sample introduction pipe; Go out sample pipe 9, link to each other with minisize detection tank with second screw 10, cover second O-ring seal 8 is in order to guarantee the sealing property of detection cell on the sample introduction pipe; Between first screw 7, second screw 10 is the liquid bath 11 that fills working fluid, and diameter is 3mm, and compound electrode places the liquid bath 11 that flows, and the central shaft of electrode and mobile liquid bath 11 is on a horizontal line; The threaded compound electrode connecting port 12 in surface, compound electrode connecting port 12 and the compound electrode 4 that is used be by spiral marking connection, in order to fixed combination electrode 4 and guarantee sealing property, the pond body 13 of minisize detection tank.
Solution enters the liquid bath 11 that flows from sample introduction pipe 6, the compound electrode 4 of flowing through, and the working electrode 1 of promptly flowing through simultaneously, contrast electrode 2 and to electrode 3 flow out from going out sample pipe 9 at last, constitute a minisize detection tank.
The compound electrode 4 that is used with minisize detection tank is as shown in Figure 1: this compound electrode is made up of electrode 3 working electrode 1, filamentary silver contrast electrode 2 and platinum filament, and working electrode can be glass carbon, gold or platinum.Successively around the periphery of working electrode, the three forms concentric circles to electrode for filamentary silver contrast electrode and platinum filament, and three electrode package become an overall electrode.
Claims (1)
1. one kind is used for the minisize detection tank that high performance liquid chromatography-electrochemical detects, it is characterized in that it is constructed as follows: sample introduction pipe (6), link to each other with minisize detection tank with first screw (7), one first O-ring seal of cover (5) is in order to guarantee the sealing property of minisize detection tank on the sample introduction pipe; Go out sample pipe (9), link to each other with minisize detection tank, go out to overlap on the sample pipe one second O-ring seal (8) in order to guarantee the sealing property of minisize detection tank with second screw (10); Be the liquid bath (11) that fills working fluid between first screw (7), second screw (10), diameter is 3mm, and compound electrode (4) places mobile liquid bath (11); Surface threaded compound electrode connecting port (12), surperficial threaded compound electrode connecting port (12) and the compound electrode (4) that is used be by spiral marking connection, in order to fixed combination electrode (4) and guarantee sealing property; The pond body (13) that also has minisize detection tank;
Described compound electrode (4) is made up of electrode (3) working electrode (1), filamentary silver contrast electrode (2) and platinum filament; Working electrode (1) is glass carbon, gold or platinum, and successively around the periphery of working electrode (1), the three forms concentric circles to electrode (3) for filamentary silver contrast electrode (2) and platinum filament, and three electrodes become an overall electrode with epoxy encapsulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510107437 CN1763544B (en) | 2005-09-30 | 2005-09-30 | Minisize detection tank for high performance liquid chromatography-electrochemical detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510107437 CN1763544B (en) | 2005-09-30 | 2005-09-30 | Minisize detection tank for high performance liquid chromatography-electrochemical detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1763544A CN1763544A (en) | 2006-04-26 |
| CN1763544B true CN1763544B (en) | 2010-05-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510107437 Expired - Fee Related CN1763544B (en) | 2005-09-30 | 2005-09-30 | Minisize detection tank for high performance liquid chromatography-electrochemical detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1763544B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101149362B (en) * | 2007-09-27 | 2010-07-21 | 北京市产品质量监督检验所 | Brewing white spirit and alcohol concocted white spirit discrimination method |
| US8342007B2 (en) * | 2010-02-10 | 2013-01-01 | Dionex Corporation | Electrochemical detection cell for liquid chromatography system |
| CN107202830A (en) * | 2017-06-15 | 2017-09-26 | 南京工业大学 | Prussian blue membrane bioelectrode detection-based device |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5011608A (en) * | 1988-11-18 | 1991-04-30 | Dragana Damjanovic | Biogenic amine assay using HPLC-ECD |
| CN1056000A (en) * | 1990-04-27 | 1991-11-06 | 中国医学科学院药物研究所 | Electrochemical tester of high-pressure liquid phose chromatograph |
| CN2328998Y (en) * | 1998-02-23 | 1999-07-14 | 中国科学院长春应用化学研究所 | Electrochemical insite quartz crystal micro balance detection pool |
| CN2414416Y (en) * | 1999-12-16 | 2001-01-10 | 中山医科大学科技开发部 | Capillary tube electrochemistry tester pool |
| CN1342899A (en) * | 2001-10-26 | 2002-04-03 | 中国科学院长春应用化学研究所 | Electrochemically luminous test pool for end of electrophoretic capillary column |
-
2005
- 2005-09-30 CN CN 200510107437 patent/CN1763544B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5011608A (en) * | 1988-11-18 | 1991-04-30 | Dragana Damjanovic | Biogenic amine assay using HPLC-ECD |
| CN1056000A (en) * | 1990-04-27 | 1991-11-06 | 中国医学科学院药物研究所 | Electrochemical tester of high-pressure liquid phose chromatograph |
| CN2328998Y (en) * | 1998-02-23 | 1999-07-14 | 中国科学院长春应用化学研究所 | Electrochemical insite quartz crystal micro balance detection pool |
| CN2414416Y (en) * | 1999-12-16 | 2001-01-10 | 中山医科大学科技开发部 | Capillary tube electrochemistry tester pool |
| CN1342899A (en) * | 2001-10-26 | 2002-04-03 | 中国科学院长春应用化学研究所 | Electrochemically luminous test pool for end of electrophoretic capillary column |
Non-Patent Citations (1)
| Title |
|---|
| 杨冰仪,莫金垣,赖容.一种基于双工作电极-双通道的毛细管电泳电化学检测系统.化学学报61 9.2003,61(9),1461-1465. * |
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| Publication number | Publication date |
|---|---|
| CN1763544A (en) | 2006-04-26 |
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Owner name: CHANGZHOU INSTITUTE OF ENERGY STORAGE MATERIALS + Free format text: FORMER OWNER: CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY HINESE ACADEMY OF SCIENCES Effective date: 20121231 |
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Free format text: CORRECT: ADDRESS; FROM: 130022 CHANGCHUN, JILIN PROVINCE TO: 213000 CHANGZHOU, JIANGSU PROVINCE |
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Effective date of registration: 20121231 Address after: Changzhou City, Jiangsu province Hehai road 213000 No. 9 Patentee after: Changzhou Institute of Energy Storage Materials & Devices Address before: 130022 Changchun people's street, Jilin, No. 5625 Patentee before: Changchun Institue of Applied Chemistry, Chinese Academy of Sciences |
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100526 Termination date: 20160930 |