CN1744913B - Cathelicidin ll-37及其衍生物在伤口愈合中的用途 - Google Patents

Cathelicidin ll-37及其衍生物在伤口愈合中的用途 Download PDF

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Publication number
CN1744913B
CN1744913B CN2004800032098A CN200480003209A CN1744913B CN 1744913 B CN1744913 B CN 1744913B CN 2004800032098 A CN2004800032098 A CN 2004800032098A CN 200480003209 A CN200480003209 A CN 200480003209A CN 1744913 B CN1744913 B CN 1744913B
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peptide
proliferation
cells
peptides
hcap18
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CN1744913A (zh
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莫娜·斯塔尔-巴克达尔
约翰·海尔博恩
安德斯·卡尔森
康尼·博根托夫特
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Promo Pharmaceuticals
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Lipopeptide AB
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N2500/30—Organic components
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CN2004800032098A 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途 Expired - Fee Related CN1744913B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510400952.7A CN105079784B (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SE03002078 2003-01-29
SE0300207A SE0300207D0 (sv) 2003-01-29 2003-01-29 New use and composition
SE0300207-8 2003-01-29
US44496403P 2003-02-05 2003-02-05
US60/444,964 2003-02-05
PCT/SE2004/000111 WO2004067025A1 (en) 2003-01-29 2004-01-28 Use of the cathelicidin ll-37 and derivatives thereof for wound healing

Related Child Applications (2)

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CN201010150582A Division CN101838326A (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途
CN201510400952.7A Division CN105079784B (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途

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CN1744913A CN1744913A (zh) 2006-03-08
CN1744913B true CN1744913B (zh) 2010-05-26

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CN201510400952.7A Expired - Fee Related CN105079784B (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途
CN2004800032098A Expired - Fee Related CN1744913B (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途
CN201010150582A Pending CN101838326A (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途

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US (5) US7452864B2 (enExample)
EP (1) EP1589987B1 (enExample)
JP (1) JP4750690B2 (enExample)
CN (3) CN105079784B (enExample)
CA (1) CA2513598C (enExample)
CY (1) CY1115142T1 (enExample)
DK (1) DK1589987T3 (enExample)
ES (1) ES2467090T3 (enExample)
PT (1) PT1589987E (enExample)
SE (1) SE0300207D0 (enExample)
SI (1) SI1589987T1 (enExample)
WO (1) WO2004067025A1 (enExample)
ZA (1) ZA200505830B (enExample)

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CN103920137B (zh) * 2014-04-28 2016-03-30 中国药科大学 一种具有抗耐药性革兰阳性细菌作用的药物组合物
WO2015183683A2 (en) * 2014-05-27 2015-12-03 Indiana University Research And Technology Corporation Peptide antagonist of ll-37
CN104984321A (zh) * 2015-07-24 2015-10-21 中国药科大学 人源抗菌肽ll-37在制备治疗或预防血栓性疾病药物中的应用
CN105859867A (zh) * 2016-05-30 2016-08-17 黄石市中心医院 一种人源抗菌肽ll-37突变体及其应用
CN106519042A (zh) * 2016-12-29 2017-03-22 陕西慧康生物科技有限责任公司 人源胶原蛋白与抗菌肽的融合蛋白及其制备方法与编码基因
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CN108659102B (zh) * 2018-04-25 2021-08-17 南方医科大学 具有抗菌及抗炎活性的多肽化合物
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PL443243A1 (pl) * 2022-12-22 2024-06-24 Uniwersytet Warszawski Nowe peptydy antydrobnoustrojowe
CN118895244B (zh) * 2024-07-23 2025-06-20 浙江自贸区中航生物科技有限责任公司 一种提高nk细胞杀伤活性的多肽及其应用
CN120789277A (zh) * 2025-09-18 2025-10-17 山东大学 一种基于(1,3)-β-D-葡聚糖合成酶抑制剂的抗真菌药物组合物

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Publication number Priority date Publication date Assignee Title
CN104513293A (zh) * 2013-09-26 2015-04-15 深圳信立泰药业股份有限公司 一种多肽疫苗的盐及其制备方法和含有该盐的药物制品

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CN101838326A (zh) 2010-09-22
DK1589987T3 (da) 2014-05-26
EP1589987B1 (en) 2014-04-23
CA2513598C (en) 2015-04-21
ZA200505830B (en) 2006-04-26
CY1115142T1 (el) 2016-12-14
ES2467090T3 (es) 2014-06-11
US20150094256A1 (en) 2015-04-02
US7452864B2 (en) 2008-11-18
CN105079784B (zh) 2018-05-18
US9125875B2 (en) 2015-09-08
PT1589987E (pt) 2014-05-28
CN105079784A (zh) 2015-11-25
CN1744913A (zh) 2006-03-08
WO2004067025A1 (en) 2004-08-12
SE0300207D0 (sv) 2003-01-29
JP2006518375A (ja) 2006-08-10
US20070149448A1 (en) 2007-06-28
JP4750690B2 (ja) 2011-08-17
CA2513598A1 (en) 2004-08-12
SI1589987T1 (sl) 2014-07-31
US20130287839A1 (en) 2013-10-31
US20110293707A1 (en) 2011-12-01
US20090088382A1 (en) 2009-04-02
US8012933B2 (en) 2011-09-06
HK1217661A1 (zh) 2017-01-20
US8936807B2 (en) 2015-01-20
EP1589987A1 (en) 2005-11-02
US8506994B2 (en) 2013-08-13

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