CN1732946B - Pharmaceutical composition for preventing and treating poultry ascites - Google Patents
Pharmaceutical composition for preventing and treating poultry ascites Download PDFInfo
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- CN1732946B CN1732946B CN 200510014583 CN200510014583A CN1732946B CN 1732946 B CN1732946 B CN 1732946B CN 200510014583 CN200510014583 CN 200510014583 CN 200510014583 A CN200510014583 A CN 200510014583A CN 1732946 B CN1732946 B CN 1732946B
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- ascites
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- treating poultry
- hexamethylenamine
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Abstract
The invention relates to a pharmaceutical composition for preventing and treating poultry ascites, which comprises Frusemide and urotropin by the weight ratio of 1:25-1:125. The composition has substantial effect in treating fowl's ascites.
Description
Technical field
The invention belongs to field of veterinary, particularly relate to a kind of pharmaceutical composition for preventing and treating poultry ascites.
Background technology
Dorking abdominal dropsy is a kind of common disease of the broiler of quick growth, is feature with tangible hydroabdomen and cardiorespiratory failure, is mainly in the broiler chicken fast of growing.This sick pathogenic factor is still very not clear at present, is commonly considered as the broiler growth excessive velocities, and oxygen consumption increases relatively, and body can not adapt to its speed of growth and cause anoxia, causes ascites.Also there is not effective method for treatment at present for this disease, can only symptomatic treatment, adopt abdominal paracentesis usually and use diuretic to come relief of symptoms, use antibiosis usually to control secondary infection.
Summary of the invention
The object of the present invention is to provide a kind of medicine-pharmaceutical composition for preventing and treating poultry ascites that can more effectively treat the fowl ascites symptoms.
The object of the present invention is achieved like this: pharmaceutical composition for preventing and treating poultry ascites, contain furosemide and hexamethylenamine, and its weight ratio is 1:25～1:125.
Proof by experiment: when furosemide and hexamethylenamine weight ratio are 1:50～1:100, can obtain better therapeutic.
Best results when furosemide and hexamethylenamine weight ratio are 1:50.
Furosemide claims furosemide again, belongs to high-ceiling diuretic, is commonly used to alleviate the ascites symptom of dorking abdominal dropsy clinically, hexamethylenamine is a Cidex-7, after for oral administration, most of with the urine discharge, in aciduria, resolve into formaldehyde and ammonia gradually and present disinfective action, hexamethylenamine is drained in urine rapidly, can take for a long time, does not have toxicity, antibacterial does not develop immunity to drugs to hexamethylenamine, the urinary tract disinfectant of doing commonly used clinically.The two organically combines, and treats in symptomatic treatment that it is basic.Furosemide can play the nephrectasia blood vessel, reduce renal vascular resistance, make especially renal cortex deep blood flow increase of renal blood flow, furosemide can also be expanded the total lung capacity vein simultaneously, reduce vascular permeability and pulmonary, add its diuresis efficiently, returned blood volume is reduced, effectively reduce pulmonary hypertension, in the shortest time, alleviate the ascites symptom; And hexamethylenamine can fundamentally be treated ascites, the formaldehyde that decomposites plays the effect of sterilization through kidney the time, do not belong to antibiotics because of hexamethylenamine simultaneously, chemical sproof generation and drug residue have been avoided effectively, add glucose as carrier, promoted the absorption of medicine, splendid for the bacillary dorking abdominal dropsy effect of treatment.
Experiment showed, that this medicine has excellent curative to fowl's ascites, experimental result is as hereinafter.
Laboratory animal adopts 220 of 1～20 aa broiler chicken, raises by normal feeding standard.21 ages in days are rejected weak chicken, sick chicken, select 200 of chickens that enter experiment, change floor husbandry over to.Take the artificial challenge to cause ascites symptoms to take place, the ascites symptoms sickness rate almost reaches 100% behind the counteracting toxic substances, the chicken group behind the inspection counteracting toxic substances, and to lose weight, abdominal part expands, and has pressed fluctuation, and it is criterion that abdominal paracentesis has yellow gel-shaped liquid.200 chickens are divided into 5 groups at random, 40 every group.1,2,3,4 groups are experimental group of the present invention, adopt prescription and the medication of embodiment 1～4.The 5th group is matched group, drink-service diuretic furosemide, every 50mg, every day twice, logotype 3 days.After the drug withdrawal 3 days, the administration experimental chicken did not have obvious clinical symptoms, and the no typical cytopathic of inspection is cutd open in sampling, is judged to healing; Sx, anti-chicken excessively are effective in the therapeutic process.
Experimental result such as following table:
Annotate: go up the number of elements that does not enter statistics in the table and be number of elements dead in experimentation, the number of elements of adding up in the table for surviving.
As can be seen from the above table, according to the situation that ascites symptoms takes place, after the medication, preceding four groups of cure rates are best apparently higher than matched group with second group effect respectively, and treatment ascites difference on effect is (p＜0.05) significantly.Remarkable by the present invention of this description of test in effect aspect the treatment fowl's ascites, when effectively controlling ascites symptoms, promote the recovery of poultry body, reduced aquaculture cost, reduced raiser's loss to greatest extent.
The specific embodiment
Embodiment 1:
Prescription: accurately take by weighing FRUSEMIDE 1.0g, hexamethylenamine 25g;
Method for making: glucose adds to 100 grams; To adopt the pneumatic conveying drying method to carry out drying after the raw material quality inspection that weigh up, pulverize the back mixing.Carry out uniformity detection, semi-finished product mensuration.Carry out leak check behind the sterile filling, prevent leakage.Be used for the treatment of fowl's ascites, add 2 gram medicines in 1 premium on currency, the administration of freely drinking water, 3 days is a course of treatment.
Embodiment 2:
Prescription: accurately take by weighing FRUSEMIDE 0.5g, hexamethylenamine 50g;
Method for making: glucose adds to 100 grams; To adopt the pneumatic conveying drying method to carry out drying after the raw material quality inspection that weigh up, pulverize the back mixing.Carry out uniformity detection, semi-finished product mensuration.Carry out leak check behind the sterile filling, prevent leakage.Be used for the treatment of fowl's ascites, add 1 gram medicine in 1 premium on currency, the administration of freely drinking water, 3 days is a course of treatment.
Embodiment 3:
Prescription: accurately take by weighing FRUSEMIDE 1g, hexamethylenamine 50g;
Method for making: glucose adds to 100 grams; To adopt the pneumatic conveying drying method to carry out drying after the raw material quality inspection that weigh up, pulverize the back mixing.Carry out uniformity detection, semi-finished product mensuration.Carry out leak check behind the sterile filling, prevent leakage.Be used for the treatment of fowl's ascites, add 1 gram medicine in 1 premium on currency, the administration of freely drinking water, 3 days is a course of treatment.
Embodiment 4:
Prescription: accurately take by weighing FRUSEMIDE 0.5g, hexamethylenamine 62.5g;
Method for making: glucose adds to 100 grams; To adopt the pneumatic conveying drying method to carry out drying after the raw material quality inspection that weigh up, pulverize the back mixing.Carry out uniformity detection, semi-finished product mensuration.Carry out leak check behind the sterile filling, prevent leakage.Be used for the treatment of fowl's ascites, add 1 gram medicine in 1 premium on currency, the administration of freely drinking water, 3 days is a course of treatment.
Claims (4)
1. a pharmaceutical composition for preventing and treating poultry ascites contains furosemide and hexamethylenamine, and its weight ratio is 1:25～1:125.
2. pharmaceutical composition for preventing and treating poultry ascites according to claim 1 is characterized in that: the weight ratio of furosemide and hexamethylenamine is 1:50～1:100.
3. pharmaceutical composition for preventing and treating poultry ascites according to claim 1 is characterized in that: the weight ratio of furosemide and hexamethylenamine is 1:50.
4. a preventing and treating poultry ascites medicine is characterized in that: adopt claim 1 or 2 or 3 described pharmaceutical composition for preventing and treating poultry ascites, add glucose and make powder as adjuvant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510014583 CN1732946B (en) | 2005-07-21 | 2005-07-21 | Pharmaceutical composition for preventing and treating poultry ascites |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510014583 CN1732946B (en) | 2005-07-21 | 2005-07-21 | Pharmaceutical composition for preventing and treating poultry ascites |
Publications (2)
| Publication Number | Publication Date |
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| CN1732946A CN1732946A (en) | 2006-02-15 |
| CN1732946B true CN1732946B (en) | 2010-07-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200510014583 Active CN1732946B (en) | 2005-07-21 | 2005-07-21 | Pharmaceutical composition for preventing and treating poultry ascites |
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| CN (1) | CN1732946B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103861422A (en) * | 2014-02-13 | 2014-06-18 | 四川省达科特能源科技有限公司 | New technique for concentrating methane in oxygen-containing coal bed gas |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102198154A (en) * | 2011-05-26 | 2011-09-28 | 河南牧翔动物药业有限公司 | Medicine composition for treating nephrosis of chicken |
-
2005
- 2005-07-21 CN CN 200510014583 patent/CN1732946B/en active Active
Non-Patent Citations (1)
| Title |
|---|
| 张子龙等.中西医结合治疗怀骡母驴腹水症.中兽医学杂志 第4期.1993,(第4期),第13页. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103861422A (en) * | 2014-02-13 | 2014-06-18 | 四川省达科特能源科技有限公司 | New technique for concentrating methane in oxygen-containing coal bed gas |
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| Publication number | Publication date |
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| CN1732946A (en) | 2006-02-15 |
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