CN1730091A - Medicine for curing lithangiuria - Google Patents

Abstract

The invention relates to a medicament for treating urinary lithiasis, which is prepared from Chinese medicinal herbs including mirabilite, climbing fern spore, chicken's gizzard-skin, amber, seed of cowherb, curcuma aromatica, giant knotweed rhizome, borax and licorice root.

Description

The medicine of treatment lithangiuria

Technical field

The present invention relates to a kind of is the Chinese patent medicine that feedstock production becomes with the Chinese herbal medicine, relates to a kind of medicine for the treatment of lithangiuria particularly.

Technical background

Lithangiuria is a kind of common diseases of urinary system, so claim urinary system calculus again.Lithangiuria patient is much, accounts for about 5% of total population.During this seizure of disease, patient is agonizing, grievous injury patient's physical and mental health.And this disease very easily recurs, and treatment causes heavy financial burden to patient repeatedly.At present the treatment of lithangiuria is mainly taked with methods such as external stone crushing, operative treatment and medicine calculus.External stone crushing causes damage to the human organ function easily, and patient's body quality is had the selection requirement, and the calculus eliminating is not thorough, easily recurrence; Surgical calculus removing is the expense height not only, have a big risk, and it is not thorough to exist calculus to get rid of equally, and easily the problem of recurrence also may produce sequela; And at present numerous general equal desirable therapeutic that can not reach of urinary calculus removing medicine that are used for, it is not thorough that the calculus in the urinary tract is got rid of, easily recurrence, particularly inoperative to the calculus in the hole district, be difficult to discharge, and in therapeutic process, the patient to stand the huge misery of urinary calculus removing.So also do not have at present a kind ofly to have, and can not bring the medicine of painful treatment lithangiuria to emerge to the patient than high curative rate.

Summary of the invention

The purpose of this invention is to provide a kind of is the medicine of raw material for treating lithangiuria with the Chinese herbal medicine, makes the lithangiuria patient be able to treatment effectively reliably under the situation of no any misery.

The medicine of treatment lithangiuria of the present invention is the medicament of being made by following proportion raw material, is expressed as follows with weight portion:

Natrii Sulfas 80～120 Spora Lygodii 50～70 Endothelium Corneum Gigeriae Galli 20～40

Succinum 10～20 Semen Vaccariae 10～20 Radix Curcumaes 10～20

Rhizoma Polygoni Cuspidati 20～40 Borax 3～10 Radix Glycyrrhizaes 10～30

Optimum weight part proportioning of its raw material of medicine of the present invention is:

Natrii Sulfas 90 Spora Lygodii 60 Endothelium Corneum Gigeriae Galli 30

Succinum 15 Semen Vaccariae 15 Radix Curcumaes 15

Rhizoma Polygoni Cuspidati 30 Borax 5 Radix Glycyrrhizaes 20

The above-mentioned medicine that is used for the treatment of lithangiuria can be made into said any dosage form on the pharmaceutics, as powder, pill, tablet, capsule and oral liquid etc.

Its preparation method is:

With crossing 120 mesh sieves after said medicine removal of contamination, oven dry, the pulverizing,, can make corresponding dosage form as required with the thin foam mix homogeneously after sieving.

Medicine of the present invention cuts down the product that ooze profit by one merit to be formed, and medicine is concentrated one's efforts suddenly, and Natrii Sulfas becomes, hardship, cold, by realification stone, and broken hard eliminating stagnation, diuresis is rushed down down; Spora Lygodii is sweet, cold, inducing diuresis for treating stranguria syndrome, calculus dampness removing; Endothelium Corneum Gigeriae Galli is sweet, flat, the silt fossil that looses, activating the spleen is good for the stomach, more than three flavor medicines be we's monarch.Succinum is sweet, flat, activating blood circulation to dissipate blood stasis, inducing diuresis for treating stranguria syndrome, but both urolith-discharging and urolith-eliminatings, but pain relieving again; Semen Vaccariae is sweet, flat, activating blood circulation to dissipate blood stasis, hard masses softening and resolving, inducing diuresis for treating stranguria syndrome; Radix Curcumae suffering, hardship, salty, promoting blood circulation and stopping pain proves according to modern pharmacological research, Radix Curcumae has solvation preferably to silt shape calculus; Rhizoma Polygoni Cuspidati Kucheng, heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, above four Chinese medicine are we's minister.Sweet, the one-tenth of Borax because of being alkalescence, can make the mucosa de-sludging, and the oral urethra that is used for sterilizes, and when particularly urine is for acidity, can make it to become alkalescence, and this is for fossil and prevent that the secondary urinary tract infection from all having good effect, and this medicine is an assistant.Radix Glycyrrhizae is sweet, flat, in the sweet mitigation, be in harmonious proportion the high strong property of above medicine, alleviate side effects of pharmaceutical drugs, this medicine is for making.Full side's compatibility, play the effect that heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, inducing diuresis for treating stranguria syndrome, urolith-discharging and urolith-eliminating lithodialysis, pain relieving activating the spleen are good for the stomach altogether, maximum size can be turned to microlith, excrete with urine after microlith is turned to powder, finally cure lithangiuria, and can effectively prevent the recurrence of disease.Compare with the medicine of other treatment lithangiuria, this medicine has the following advantages:

One, fossil is thoroughly clean, does not recur or seldom recurrence.This medicine can all melt big microlith, thus lithangiuria patient non-relapse after healing or seldom recurrence, and operation and lithotripsy in treatment can only remove bigger calculus, can't remove minimum calculus, so very easily recurrence.

Misery unbearably when two, the patient does not have calculus in the therapeutic process.This medicine can thoroughly excrete (person does not see that the calculus or the grains of sand are arranged in the urine to take this medicine) after the dissolving with calculus, is not directly calculus, the grains of sand to be excreted, so unbearably pain when the patient does not have calculus can not damaged urethra.

Three, therapeutic domain is wide, and is evident in efficacy, has no side effect.This medicine can be treated renal calculus, ureteral calculus, vesical calculus, urinary stone, cholelithiasis also there is certain curative effect, particularly cureless intractable calculus (as the calculus in the hole district) and multiple calculus are had special efficacy, effective percentage reaches more than 95%, and cure rate reaches more than 85%.This medicine is that the Chinese herbal medicine of pure natural is formed, and has no side effect after taking.

Four, take medicine conveniently, the treatment phase is short, not influence work life.This medicine is to state of an illness the lighter, and can cure a course of treatment (one month), can cure two to three courses of treatment the heavy person of the state of an illness, but period in a medicine operate as normal, work does not have influence to life.

Five, the risk of no operative treatment and sequela, and the rubble therapy is to the infringement of patient's internal organs function.

Six, the medicine valency is low, thereby makes medical expense cheap, can alleviate the patient medical cost burden.

The clinical experiment report (shown in the table of back) that uses medicine of the present invention (powder) that 20 routine lithangiuria patients are treated:

One, patient's situation

1, sex and age: male's 12 examples, 32～69 years old age; Women's 8 examples, 30～65 years old age;

2, symptom situation: simple renal calculus 10 examples (calculus accounts for 7 examples at Dou Qu), simple ureteral calculus 5 examples, mixed type calculus 5 examples;

3, treatment history situation: 15 examples of treatment history are arranged before the prescription on individual diagnosis, and treatment does not first have 5 examples for the treatment of history.

Two, treatment standard

1, cure: symptom and sign disappears, ultrasound diagnosis, and calculus disappears;

2, effective: symptom is clearly better, ultrasound diagnosis, and calculus quantity reduces, and calculus diminishes, and the calculus position moves down;

3, invalid: symptom does not have obvious improvement, calculus quantity, big or small no change.

Three, administrated method and consumption

Early ante cibum, a.p with before the sleeping at night use warm boiled water, each 10 grams, totally 30 restrain (old man and child are cut down according to the circumstance) every day, one month is a course of treatment.

Four, therapeutic outcome

Through the treatment of 1～3 course of treatment, among the 20 routine patients, to remove 1 example and stop treatment because of the manual labour of going out, 1 example effectively back is used earthwork treatment instead because of the household economy difficulty, outside 1 example is invalid, all the other all healings of 17 examples, cure rate 85%, effective percentage 95%, inefficiency 5%.

Five, points for attention

1, anemia of pregnant woman, wet nurse avoid usefulness, Deficiency and coldness of spleen and stomach, the careful usefulness of oedema due to nephritis person;

2, the part patient slight stomachache can occur at take medicine initial several days (the whole period in a medicine of individual patient), times of defecation increases, not molding or slight diarrhoea, (if the serious diarrhoea of symptom Lock-out after a period of time or the drug withdrawal of taking medicine, drug withdrawal immediately illustrates that the patient has incompatibility to take other disease of this medicine);

3, period in a medicine is eaten stimulus object such as Fructus Capsici, liquor with high degree as far as possible less;

4, continue to take this medicine (about 10 days) to consolidate curative effect after the healing.

The specific embodiment

Embodiment one:

Take by weighing raw material by following proportioning:

Natrii Sulfas 90Kg Spora Lygodii 60Kg Endothelium Corneum Gigeriae Galli 30Kg

Succinum 15Kg Semen Vaccariae 15Kg Radix Curcumae 15Kg

Rhizoma Polygoni Cuspidati 30Kg Borax 5Kg Radix Glycyrrhizae 20Kg

To cross 120 mesh sieves after said medicine removal of contamination, oven dry, the pulverizing, with the thin foam mix homogeneously after sieving, subpackage is packaged into powder.

Embodiment two:

Take by weighing raw material by following proportioning:

Natrii Sulfas 80Kg Spora Lygodii 52Kg Endothelium Corneum Gigeriae Galli 38Kg

Succinum 10Kg Semen Vaccariae 20Kg Radix Curcumae 18Kg

Rhizoma Polygoni Cuspidati 22Kg Borax 8Kg Radix Glycyrrhizae 14Kg

To cross 120 mesh sieves after said medicine removal of contamination, oven dry, the pulverizing, with the thin foam mix homogeneously after sieving, subpackage is packaged into powder.

Embodiment three:

Take by weighing raw material by following proportioning:

Natrii Sulfas 118Kg Spora Lygodii 70Kg Endothelium Corneum Gigeriae Galli 22Kg

Succinum 20Kg Semen Vaccariae 14Kg Radix Curcumae 12Kg

Rhizoma Polygoni Cuspidati 39Kg Borax 3Kg Radix Glycyrrhizae 28Kg

To cross 120 mesh sieves after said medicine removal of contamination, oven dry, the pulverizing, with the thin foam mix homogeneously after sieving, subpackage is packaged into powder.

Sequence number	Sex	Age	With regard to the rash time	Have or not the treatment history	Situation during prescription on individual diagnosis (through ultrasound diagnosis)	Check situation (through ultrasound diagnosis) after 1 month	Check situation after 2 months	Check situation after 3 months	Remarks
										1	The man	48	19991209	Obeyed multiple in, two medicines, poor effect	Visible 0.5～the 0.8cm in right side ureter upper end 5 calculus that differ in size, pain unbearably	Calculus all disappears, two kidney double ureter no abnormality seens, and symptom is eliminated, and cures			So far not recurrence
2	The woman	30	20000504	Treatment had 2 years repeatedly	The multiple calculus that the visible respectively 0.3～0.5cm of double ureter upper and lower end differs in size, pain	The double ureter no abnormality seen, calculus disappears, and symptom is eliminated, and cures			So far not recurrence
										3	The woman	53	20000807	Do not have	Left side renal calculus (renal pelvis 0.5cm, last small cup 0.4cm, an inferior calyx 0.6cm) dripping sweat, pain unbearably	Calculus all disappears, and symptom is eliminated, and cures			So far not recurrence
4	The man	65	20001203	Twice calculus row of a specified duration do not go out to the large hospital treatment	Visible 0.8 * 0.6cm the high light of left ureter bladder opening part group accompanying sound shadow, pain unbearably	Two kidney double ureters, bladder no abnormality seen, calculus disappears, and symptom is eliminated, and cures			So far not recurrence
										5	The woman	51	20000304	3 years calculus medical histories are arranged, hospital treatment repeatedly, obstinate	The left side sinus renalis visible 0.3～1.2cm in the district strong echo light group accompanying sound shadow that differs in size, health as weak as water, the waist distending pain	Calculus is little to differ in size to 0.3～0.7cm, and health takes a turn for the better, and waist only expands not bitterly	The CT examination calculus all disappears, and symptom is eliminated, and physical recovery health is cured		So far not recurrence
6	The woman	38	20010509	Cured recurrence again after the healing three times	The multiple calculus companion of right kidney hydrops, maximum 0.6cm, minimum big as the grain of rice, the waist distending pain	Hydrops and calculus disappear, and symptom is eliminated, and cure			So far not recurrence
										7	The man	69	20011103	Calculus medical history is for many years arranged, obstinate	Two sinus renalis district 0.5～1.3cm high light group accompanying sound shadow that differs in size, the slight hydrops of right kidney, the waist distending pain is unbearably	Hydrops disappears, and calculus is little of 0.3～0.6cm, and the waist distending pain alleviates			Because of financial difficulties, use a cubic metre of earth treatment instead

Sequence number	Sex	Age	With regard to the rash time	Have or not the treatment history	Situation during prescription on individual diagnosis (through ultrasound diagnosis)	Check situation (through ultrasound diagnosis) after 1 month	Check situation after 2 months	Check situation after 3 months	Remarks
										8	The man	36	20020406	6 years calculus medical histories are arranged, obstinate	Right sinus renalis district visible 2.3cm high light group accompanying sound shadow,	Calculus does not have significant change, and is invalid			Carry out operative treatment after the drug withdrawal
9	The man	48	20020603	Do not have	The slight hydrops of left side kidney, visible 0.5 * 0.8cm the high light of last small cup group accompanying sound shadow, there is microlith the left ureter upper end, and the waist distending pain unbearably	Hydrops and calculus disappear, and distending pain is eliminated, and cure			So far not recurrence
										10	The man	32	20020709	Do not have	Two kidney silt calculus, maximum 0.2 * 0.3cm, waist distending pain	Calculus disappears, and distending pain is eliminated, and cures			So far not recurrence
11	The man	46	20020906	2 years calculus medical histories, to hospital take medicine, rubble is invalid	Two companions of right kidney renal pelvis 0.6～0.8cm calculus moderate hydrops, two the 0.5 * 0.6cm calculus in ureter upper end, vesical calculus 0.8 * 0.7cm, the waist distending pain	Right kidney renal pelvis also has 2 grain of rice maximum sizes, and hydrops and other calculus disappear			Do manual work because of going out, stop treatment
										12	The woman	38	20021009	3 years calculus medical histories are rubble several times, and calculus is arranged endless	Two sinus renalis district 0.3～0.5 high light group accompanying sound shadow that as seen differs in size, slight hydrops, lumbago is unbearably	The hydrops calculus all disappears, and lumbago is eliminated, and cures			So far not recurrence
13	The man	50	20030112	Do not have	Right sinus renalis district visible 0.4 * 0.5cm high light group accompanying sound shadow, lumbago unbearably	Calculus disappears, two kidney double ureter no abnormality seens, and lumbago is eliminated, and cures			So far not recurrence
										14	The man	35	20030306	Do not have	Double ureter 0.3～0.4cm high light group accompanying sound the shadow that all as seen differs in size, rib pain unbearably	Calculus all disappears, two kidney double ureter bladder no abnormality seens, and pain is eliminated, and cures			So far not recurrence

Sequence number	Sex	Age	With regard to the rash time	Have or not the treatment history	Situation during prescription on individual diagnosis (through ultrasound diagnosis)	Check situation (through ultrasound diagnosis) after 1 month	Check situation (ultrasound diagnosis) after 2 months	Check situation after 3 months	Remarks
										15	The woman	65	20030709	3 years calculus medical histories are arranged, outbreak repeatedly, obstinate	Two kidney double ureters and bladder all have 0.3cm left and right sides microlith, waist, rib pain	Calculus all disappears, and pain is eliminated, and cures			So far not recurrence
16	The woman	53	20030916	5 years calculus medical histories are arranged, obstinate	The all visible 0.4～1.8cm in the two sinus renalis district strong echo light group accompanying sound shadow that differs in size, the slight hydrops of left kidney, the pain in the lumbar region pain is endlessly	Left side hydronephrosis disappears, and two sinus renalis district calculus is little of 0.4～1.0cm, and pain is eliminated	0.3 * 0.4cm the calculus in only left sinus renalis district	The contrast examination calculus disappears entirely, cures	So far not recurrence
										17	The man	49	20040203	Calculus medical history one year, through more than ten times repeatedly rubble do not heal	Left side sinus renalis district 1.7cm high light group accompanying sound shadow, 0.8～1.2cm high light group accompanying sound shadow that differs in size in the double ureter, the health extremely feeble	The calculus in sinus renalis district, a left side is little of 0.3cm, and left ureter has only 2 0.2～0.3 cm microliths, and right ureter is normal	Sinus renalis district, left side calculus is little of 0.2 cm, all the other disappearances	The CT examination calculus disappears entirely, cures	So far not recurrence
18	The woman	42	20040618	Calculus medical history one year, the lithotrity effect of taking medicine is all not good	Left side kidney renal pelvis 0.4 * 0.5cm high light group accompanying sound shadow, right ureter lower end 3 strong echo lights of 0.3～0.4cm size group accompanying sound shadow, waist rib pain	Calculus all disappears, and pain is eliminated, and cures			So far not recurrence
										19	The man	63	20040906	3 years calculus medical histories are arranged, cure recurrence again	The high light group accompanying sound shadow of the visible 0.4 * 0.5cm in right ureter upper end, the flank distending pain unbearably	Calculus all disappears, and pain is eliminated, and cures			So far not recurrence
20	The man	35	20050112	2 years calculus medical histories are arranged, invalid through hospital administration, rubble	Visible 6 of two sinus renalis district (about each 3) 0.8 * 1.2cm high light group accompanying sound shadow, the waist distending pain unbearably	5 calculus disappear, and remaining one is had only 0.5cm, continues medication 10 days, and calculus all disappears, and pain is eliminated, and cures			So far not recurrence

Claims (2)

1, a kind of medicine for the treatment of lithangiuria is characterized in that: it is the medicament of being made by following weight (part) proportion raw material:

Natrii Sulfas 80～120 Spora Lygodii 50～70 Endothelium Corneum Gigeriae Galli 20～40

Succinum 10～20 Semen Vaccariae 10～20 Radix Curcumaes 10～20

Rhizoma Polygoni Cuspidati 20～40 Borax 3～10 Radix Glycyrrhizaes 10～30.

2, the medicine of treatment lithangiuria according to claim 1 is characterized in that: wherein the weight of each raw material (part) proportioning is:

Natrii Sulfas 90 Spora Lygodii 60 Endothelium Corneum Gigeriae Galli 30

Succinum 15 Semen Vaccariae 15 Radix Curcumaes 15

Rhizoma Polygoni Cuspidati 30 Borax 5 Radix Glycyrrhizaes 20.