CN1723963A - Health-care food with spot-removing function - Google Patents

Health-care food with spot-removing function Download PDF

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Publication number
CN1723963A
CN1723963A CN 200510019054 CN200510019054A CN1723963A CN 1723963 A CN1723963 A CN 1723963A CN 200510019054 CN200510019054 CN 200510019054 CN 200510019054 A CN200510019054 A CN 200510019054A CN 1723963 A CN1723963 A CN 1723963A
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China
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spot
removing function
water
health food
under reduced
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CN 200510019054
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CN100356934C (en
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陈学锋
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Abstract

A health-care food with the spot-removing function is prepared from wolfberry leaf through removing impurities, decocting, filtering, vacuum concentrating, adding starch, calcium hydrogen phosphate and talc powder, stirring, drying, pulverizing, preparing capsules or tablets. It can be also used to prepare oral liquid.

Description

A kind of health food with spot-removing function
Technical field
The invention belongs to field of health care food with spot-removing function.
Background technology
Chloasma, form in human body skin by melanin pigmentation, the melanocyte of entering angle albuminous cell can be come off with keratinocyte by lysosome degraded back, when the intravital flesh lipid content of machine raises, lysosomal vigor descends, the degradation speed of melanocyte is slack-off thereupon, will form chloasma at skin surface.Because the blood stasis that a variety of causes causes can make poor blood circulation and metabolic function weaken, and causes intravital rubbish in time to get rid of, vivotoxin, lipofuscin increase, and in the course of time, will be reflected to body surface, form mottle.Timely blood circulation promoting and blood stasis dispelling, but the accelerate blood circulation enhance metabolism, increase and get rid of the melanin that melanocyte produced, promote to be stranded in intravital melanin and decompose, make it and can not become mottle by precipitation form, or settled pigment is decomposed excrete.
At present the common health food with spot-removing function in market is a lot, but health-care effect differs, and the manufacturing cost that has is higher, and the production technology that has is complicated, can not satisfy people's needs.Folium Engelhardia roxburghina is the tea-drinking of often doing among the people in Guangxi, has heat-clearing and toxic substances removing, promoting the production of body fluid to quench thirst, the effect of expelling summer-heat dampness removing.Be used for the taste humidity hysteresis, the auxiliary treatment that breast abdominal distention is vexed is not used for the treatment of chloasma but appear in the newspapers, may be also not obvious relevant with its therapeutic effect.As through certain purification, its spot-removal function composition is assembled, will improve the curative effect of treatment chloasma.
Folium Engelhardia roxburghina is the dried leaves of juglandaceae plant Engelhardtia roxburghiana Engelhardia roxburghiana Wall..It distinguishes the flavor of little sweet, and is cool in nature, has another name called Tea of momordica grosvenori, Folium hydrangeae strigosae, Guiping Folium hydrangeae strigosae.Mainly contain flavone compound, Astilbin, different Astilbin, new Astilbin etc.The contained Astilbin of Folium Engelhardia roxburghina has the effect of anti-inflammatory, and flavone compound has the effect of tangible function of promoting blood circulation to disperse blood clots and anticoagulant, blood fat reducing, blood sugar lowering, enhancing immunity.The method, rat acute " blood stasis " card hemorheology index, hyperlipidemia mice lipids contents and the normal pressure hypoxia endurance time etc. that adopt the multiple CAL of rabbit plasma, rats in vitro platelet aggregation and thrombus in vivo to form, observe the function of promoting blood circulation to disperse blood clots of Engelhardia roxburghina Wall.total flavones, Engelhardia roxburghina Wall.total flavones has external anticoagulant, antiplatelet aggregation and anti-thrombosis function as a result, energy blood viscosity lowering and blood lipid level prolong hypoxia endurance time; The clotting time that the mice thrombotest is also shown Engelhardia roxburghina Wall.total flavones energy significant prolongation mice, can obviously shorten the caused breathing dyspnea with rapid and short breath persistent period of the inductive platelet aggregation pulmonary infarction of ADP, can reduce serum total cholesterol and the content of triglyceride of hypercholesterolemia animal, and the serum high-density LP cholesterol level is raise, reduce alloxan diabetes mouse blood sugar level; And promotion mononuclear-macrophage phagocytic function.Acute toxicity test in mice shows that Engelhardia roxburghina Wall.total flavones toxicity is very little, and its maximum tolerated dose is 19.8g/kg.
Pharmacodynamic experiment shows that it has tangible function of promoting blood circulation to disperse blood clots, and toxicity is very low, so the Folium Engelhardia roxburghina of commonly using among the people is that herbal tea is drunk.
Summary of the invention
The technical problem to be solved in the present invention provides the health food that a kind of raw material is easy to get, prepares easily, good spot-removing function is arranged.
The present invention solves the problems of the technologies described above with following technical scheme:
Raw material: Folium Engelhardia roxburghina
Preparation method:
Get Folium Engelhardia roxburghina, choose the removal of impurity, decoct with water, filter.Extracting solution is evaporated to the thick paste shape, with starch, calcium hydrogen phosphate, Pulvis Talci mix homogeneously, drying, pulverizes, and packing, packing, promptly.
The health food of tool spot-removing function of the present invention, taking dose is little, and freckle effect is remarkable, and production technology is simple, and moderate cost is beneficial to consumer and takes.
The specific embodiment
In state-owned thousands of years cultural and historical, among the peoplely exist very abundant medical wealth.Along with development of modern science and technology, further excavating, develop Chinese medicine has become the problem that people more and more note.The raw materials used right plant Folium Engelhardia roxburghina on daytime of getting fully of the present invention, its side effect is little, toxicity is little, and it is refined processing, and its speckle dispelling effective ingredient is assembled, and uses single medicinal material just can give full play to the health therapy function of medicine.
The manufacturing process of this health food is after Folium Engelhardia roxburghina is chosen the removal of impurity, to decoct with water, and filters, and extracting solution is evaporated to extractum, and with starch, calcium hydrogen phosphate, Pulvis Talci mix homogeneously, drying under reduced pressure, dried cream powder is broken, sieve, and packing, packing get product.
For conveniently taking, the first-selected dosage form of this product is a capsule.Because the easy moisture absorption of Folium Engelhardia roxburghina the water extracted immersing paste reduces its hygroscopicity so add adjuvants such as starch, calcium hydrogen phosphate, adds Pulvis Talci and regulates powder flowbility, preparation process will guarantee that loading amount is accurate, and three kinds of adjuvants all meet the requirement of food stage sanitary standard.In addition, this product also can be made into tablet, granule, emplastrum, mixture, drop pill, ointment, medicinal tea and liniment etc.
The investigation of product clinical efficacy:
One. the case choice criteria:
1. tcm diagnosis standard:
(1) bleeding due to blood-heat card
Primary symptom: skin speckle color is scarlet or purple dark, even blackout, heating, excessive thirst.
Inferior disease: onset is hurried, dark coloured urine constipation, or joint waist abdomen pain, red tongue with yellow fur, slippery and rapid pulse or stringy and rapid pulse.
(2) syndrome of yin deficiency and blood heat
Primary symptom: skin speckle color is scarlet or purple dark, dysphoria with feverish sensation in the chest palms and soles, xerostomia, hectic fever night sweat.
Inferior disease: the course of disease is longer, the time when sending out more, have a dizzy spell, constipation, dry tongue is red, few tongue or no fur, thready and rapid pulse.
(3) deficient QI failing to control card
Primary symptom: skin speckle color is light red, and spiritlessness and weakness is breathed hard.
Inferior disease: the course of disease is longer, the time when sending out more, pale or sallow complexion, dizziness, spontaneous perspiration, lack of appetite, loose stool.
(4) blood-stasis internal-depression card
Primary symptom: skin speckle color is purple black, and dim complexion or lip refer to livid purple.
Inferior disease: cardiopalmus, insomnia, breast or waist abdomen be pain fixedly, purplish tongue or purpura is arranged, hesitant pulse.
2, include the case standard in: meet the diagnostic criteria of primary disease tcm syndrome, can include the test case in.
(1) under the prerequisite that does not influence patient's life security, after withdrawing former 1 week of treatment thrombocytopenia medicine, still meets tcm diagnosis standard person.After stable at least 1 week, can include test at dosage in.
(2) be the main object of observation with state of an illness classification moderate.
3, exclusion standard
(1) secondary thrombocytopenic purpura is as connective tissue disease, disease of immune system, disease in the blood system, hematological system tumor, the hypersplenism person etc. that cuts the spleen.
(2) allergic constitution or to multiple drug allergy person.
Two, efficacy determination
1, clinical recovery tcm clinical practice symptom, sign disappear or basic the disappearance.
2, produce effects tcm clinical practice symptom, sign are obviously improved.
3, effectively tcm clinical practice symptom, sign all take a favorable turn.
4, invalid tcm clinical practice symptom, sign all do not have obvious improvement, even increase the weight of.
Get every this product capsule that contains 0.5 gram, each three, every day three times, serve on ten days.
Product curative effect survey result table
The example number The product curative effect
Clinical recovery Produce effects Effectively Invalid
93 66 71.0 18 19.4 7 7.5 2 2.2
Embodiment 1:
1, get Folium Engelhardia roxburghina 2500g, choose the removal of impurity, decoct with water 2 times, add 12 times of amounts of water for the first time, extracted 2 hours, add 10 times of amounts of water for the second time, extracted 1 hour, merge extractive liquid, filters.
2, the extracting solution concentrating under reduced pressure (100 ℃ of temperature, pressure 70~80KPa) to relative density are the extractum of 1.30~1.35 (50 ℃), with starch 20g, calcium hydrogen phosphate 30g, Pulvis Talci 15g mix homogeneously, at 80 ℃, the 10kPa drying under reduced pressure.
3, dried cream powder is broken, crosses 60 mesh sieves, the dress capsule, and the 0.5g/ grain, packing, promptly.
Embodiment 2:
1, get Folium Engelhardia roxburghina 2000g, choose the removal of impurity, decoct with water 2 times, add 10 times of amounts of water for the first time, extracted 1.5 hours, add 8 times of amounts of water for the second time, extracted 1 hour, merge extractive liquid, filters.
2, the extracting solution concentrating under reduced pressure (90 ℃ of temperature, pressure 80~90KPa) to relative density are the extractum of 1.25~1.30 (50 ℃), with starch 30g, calcium hydrogen phosphate 20g, Pulvis Talci 30g mix homogeneously, at 60 ℃, the 10kPa drying under reduced pressure.
3, dried cream powder is broken, crosses 80 mesh sieves, the dress capsule, and the 0.4g/ grain, packing, promptly.
Embodiment 3:
1, get Folium Engelhardia roxburghina 3000g, choose the removal of impurity, decoct with water 2 times, add 10 times of amounts of water for the first time, extracted 3 hours, add 8 times of amounts of water for the second time, extracted 2 hours, merge extractive liquid, filters.
2, the extracting solution concentrating under reduced pressure (85 ℃ of temperature, pressure 65~75KPa) to relative density are the extractum of 1.30~1.35 (50 ℃), with starch 10g, calcium hydrogen phosphate 20g, Pulvis Talci 20g mix homogeneously, at 70 ℃, the 10kPa drying under reduced pressure.
3, dried cream powder is broken, granulates tabletting, every heavy 0.33 gram.
Embodiment 4:
Get Folium Engelhardia roxburghina 1600 grams, choose the removal of impurity, decoct with water 2 times, add 12 times of amounts of water for the first time, extracted 2 hours, add 10 times of amounts of water for the second time, extracted 2 hours, merge extractive liquid, filters.The extracting solution concentrating under reduced pressure (85 ℃ of temperature, 70~80KPa) to 1000 milliliters of pressure, put cold, the bottling, 10 milliliters every bottle.

Claims (4)

1. the health food with spot-removing function is characterized in that raw material is a Folium Engelhardia roxburghina.
2. preparation method with health food of spot-removing function, the preparation technology who it is characterized in that capsule gets Folium Engelhardia roxburghina, chooses the removal of impurity, decocts with water, and filters; Extracting solution is evaporated to the thick paste shape, with starch, calcium hydrogen phosphate, Pulvis Talci mix homogeneously, drying, pulverizes, and packing, packing, promptly.
3. preparation method with health food of spot-removing function, the preparation technology who it is characterized in that tablet gets Folium Engelhardia roxburghina, chooses the removal of impurity, decocts with water, filters; The extracting solution concentrating under reduced pressure is an extractum, with starch, calcium hydrogen phosphate, Pulvis Talci mix homogeneously, drying under reduced pressure; Dried cream powder is broken, granulates, and tabletting promptly.
4. preparation method with health food of spot-removing function, the preparation technology who it is characterized in that oral liquid gets Folium Engelhardia roxburghina, chooses the removal of impurity, decocts with water, filters; The extracting solution concentrating under reduced pressure, put cold, the bottling promptly.
CNB2005100190543A 2005-07-04 2005-07-04 Health-care food with spot-removing function Expired - Fee Related CN100356934C (en)

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CN1723963A true CN1723963A (en) 2006-01-25
CN100356934C CN100356934C (en) 2007-12-26

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579567A (en) * 2012-04-10 2012-07-18 广西壮族自治区中医药研究院 Medicine for treating diabetes and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163138A (en) * 1997-04-11 1997-10-29 广西陆川县鸿辉茶品有限公司 Ganzhao tea and its preparation process

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579567A (en) * 2012-04-10 2012-07-18 广西壮族自治区中医药研究院 Medicine for treating diabetes and preparation method thereof

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