CN1709421A - Medicinal formulation for preventing and treating stomach and digestive tract diseases - Google Patents
Medicinal formulation for preventing and treating stomach and digestive tract diseases Download PDFInfo
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- CN1709421A CN1709421A CN 200510076815 CN200510076815A CN1709421A CN 1709421 A CN1709421 A CN 1709421A CN 200510076815 CN200510076815 CN 200510076815 CN 200510076815 A CN200510076815 A CN 200510076815A CN 1709421 A CN1709421 A CN 1709421A
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Abstract
The present invention relates to a Chinese medicine preparation for curing the diseases of gastritis, gastric ulcer, enteritis, dyspepsia and auxiliary therapy of prophase pathologic change of carcinoma of digestive tract and postoperative digestive tract. Said Chinese medicine preparation is made up by using the Chinese medicinal materials of rabdosia amethystoider and ginseng or codonopsis root or American ginseng through a certain preparation process, and can be made into various conventional dosage forms.
Description
The present invention relates to a kind of effect that invigorating the spleen and benefiting QI, promoting blood circulation and detoxication, circulation of qi promoting remove painful abdominal mass that has, be used for gastritis, gastric ulcer, enteritis, dyspepsia, digestive tract cancer cercinoma prophase pathologic change and digestive tract cancer operation back auxiliary treatment, can improve significantly that flatulence, upper abdomen dull pain, belch, appetite are poor, the pharmaceutical preparation of spiritlessness and weakness clinical symptoms, this pharmaceutical preparation is monarch drug with the Herba Rabdosiae glaucocalycis with promoting flow of QI and blood, antipyretic and antidote functions, the Radix Ginseng of tonifying QI to produce body fluid effect or Radix Codonopsis or Radix Panacis Quinquefolii and activating QI to eliminate phlegm, removing food stagnancy removes the Fructus Aurantii of painful abdominal mass to be formed for the minister adjuvant drug, and its prescription is:
Prescription 1:
Radix Ginseng 50g～150g Herba Rabdosiae glaucocalycis 1000g～3000g Fructus Aurantii 150g～350g
Prescription 2:
Radix Codonopsis 50g～2000g Herba Rabdosiae glaucocalycis 1000g～3000g Fructus Aurantii 150g～350g
Prescription 3:
The Radix Ginseng that Radix Panacis Quinquefolii 50g～200g Herba Rabdosiae glaucocalycis 1000g～3000g Fructus Aurantii 150g～350g wherein fills a prescription in 1 comprises wild ginseng, Radix Ginseng Rubra, Korean Ginseng.
For achieving the above object, the present invention also provides the preparation method of this pharmaceutical preparation:
Preparation method 1: above three flavors, prescription Radix Ginseng or the fill a prescription Radix Codonopsis in 2 or the Radix Panacis Quinquefolii powder of filling a prescription in 3 in 1 is broken into fine powder, and be standby; Herba Rabdosiae glaucocalycis is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Fructus Aurantii is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered, and filtrate is mixed with above-mentioned filtrate, is concentrated into the cream that relative density is 1.10-1.20, and drying under reduced pressure adds fine powder, mixing, promptly.
Preparation method 2: above three flavors, prescription Radix Ginseng or the fill a prescription Radix Codonopsis in 2 or the Radix Panacis Quinquefolii powder of filling a prescription in 3 in 1 is broken into coarse powder, adds 5-10 times of water gaging and decocts secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Herba Rabdosiae glaucocalycis is ground into coarse powder and adds 5--10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Fructus Aurantii is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered, and filtrate is mixed with above-mentioned filtrate, is concentrated into the cream that relative density is 1.10-1.20, and drying under reduced pressure adds appropriate amount of auxiliary materials, mixing, promptly.
Preparation method 3: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or fill a prescription the Radix Panacis Quinquefolii 3 in of prescription in 1 is ground into coarse powder with Herba Rabdosiae glaucocalycis with Fructus Aurantii and adds 5-10 times of water gaging and decoct three times, each 1～3 hour, collecting decoction, filter, filtrate is concentrated into the cream that relative density is 1.10-1.20, drying under reduced pressure, mixing, promptly.
Preparation method 4: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or the Radix Panacis Quinquefolii powder of filling a prescription 3 in of prescription in 1 is broken into coarse powder, add 30%～95% ethanol 5-10 and doubly measure reflux, extract, or percolation 1--3 time, each 3 hours, merge extractive liquid, or percolate, filter, decompression filtrate recycling ethanol, the cream that is concentrated into relative density and is 1.30-1.38 is standby; Herba Rabdosiae glaucocalycis is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Fructus Aurantii is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered, and filtrate is mixed with above-mentioned filtrate, is concentrated into the cream that relative density is 1.10-1.20, drying under reduced pressure, and mixing, promptly
Preparation method 5: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or the Radix Panacis Quinquefolii powder of filling a prescription 3 in of prescription in 1 is broken into coarse powder, add 30%～95% ethanol 5-10 and doubly measure reflux, extract, or percolation 1--3 time, each 3 hours, merge extractive liquid, or percolate, filter, decompression filtrate recycling ethanol, the cream that is concentrated into relative density and is 1.30-1.38 is standby; Herba Rabdosiae glaucocalycis and Fructus Aurantii are ground into coarse powder and decoct with water 1--3 time, and each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the cream that relative density is 1.10-1.20, drying under reduced pressure, and mixing, promptly
Preparation method 6: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or fill a prescription the Radix Panacis Quinquefolii powder 3 in of prescription in 1 is broken into coarse powder and adds 30%～95% ethanol 5-10 with Herba Rabdosiae glaucocalycis with Fructus Aurantii and doubly measure reflux, extract, or percolation 1--3 time, each 3 hours, merge extractive liquid, or percolate filter decompression filtrate recycling ethanol, be concentrated into the cream that relative density is 1.30-1.38, drying under reduced pressure, mixing, promptly.
The present invention also provides the preparation method of this pharmaceutical preparation tablet, capsule, granule, pill, pellet, powder, mixture, soft capsule, drop pill, unguentum:
Embodiment 1: the method for preparing this pharmaceutical preparation tablet:
The first step: with preparation method 1-6
Second step: add an amount of dressing as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, ethanol, mixing, tabletting, packing, promptly.
Embodiment 2: the method for preparing this pharmaceutical preparation capsule:
The first step: with preparation method 1-6
Second step: add an amount of dressing as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, ethanol, mixing, encapsulated, promptly.
Embodiment 3: the method for preparing this pharmaceutical preparation granule:
The first step: with preparation method 1-6
Second step: add an amount of dressing as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, mixing, packing, promptly.
Embodiment 4: the method for preparing this pharmaceutical preparation pill:
The first step: with preparation method 1-6
Second step: add an amount of dressing as Mel, starch, dextrin, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, mixing, make honeyed pill, the watered pill, paste pill, concentrated pill, wax pill and the micropill of ball-type or class ball-type, packing, promptly.
Embodiment 5: the method for preparing this pharmaceutical preparation powder:
The first step: with preparation method 1-6
Second step: direct packaging or add an amount of dressing as starch, dextrin, sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, silicon dioxide, aluminium hydroxide, ethanol, mixing, packing, promptly.
Embodiment 6: the method for preparing this pharmaceutical preparation mixture:
The first step: with preparation method 1-6
Second step: add an amount of dressing as sucrose, microcrystalline Cellulose, hyprolose, methylcellulose, ethyl cellulose, Carboxymethyl cellulose sodium, water, ethanol, antiseptic, mixing, packing, promptly.
Embodiment 7: the method for preparing this pharmaceutical preparation soft capsule:
The first step: with preparation method 1-6
Second step: adds an amount of dressing as: vegetable oil, glycerol compacting or drip and make, packing, promptly.
Embodiment 8: the method for preparing this pharmaceutical preparation drop pill:
The first step: with preparation method 1-6
Second step: adds an amount of dressing as Polyethylene Glycol, gelatin, stearic acid, glyceryl monostearate, hydrogenated vegetable oil, ethanol, mixing splashes in the condensed fluid, and condensed fluid is removed in the contraction condensation, packing, promptly.
Embodiment 9: the method for preparing this pharmaceutical preparation agent unguentum:
The first step: with preparation method 1-6
Second step: add an amount of dressing as starch, dextrin, sucrose, cellulose, antiseptic, ethanol, mixing, packing, promptly.
This pharmaceutical preparation is on the basis of Traditional Chinese medical theory, study in conjunction with modern Chinese medicine, invention have invigorating the spleen and benefiting QI, a promoting blood circulation and detoxication, circulation of qi promoting removes the effect of painful abdominal mass, is used for gastritis, gastric ulcer, enteritis, dyspepsia, digestive tract cancer cercinoma prophase pathologic change and digestive tract cancer operation back auxiliary treatment; The thing preparation of a kind of prophylactic treatment stomach and digestive tract disease can significantly improve the pharmaceutical preparation of clinical symptoms such as flatulence, upper abdomen dull pain, belch, appetite are poor, spiritlessness and weakness, wherein Radix Ginseng, Radix Codonopsis, Radix Panacis Quinquefolii have the effect of benefiting qi and nourishing blood, Herba Rabdosiae glaucocalycis is the capable section of a lip plant, have promoting flow of QI and blood, antipyretic and antidote functions, can improve gastric mucosal lesion position blood circulation state, diminish inflammation, promote the effect of mucosa regeneration; And the Fructus Aurantii activating QI to eliminate phlegm, the stagnant relieving distension of row, removing food stagnancy removes painful abdominal mass, both can prevent nourishing the fraud of stagnant gas, and the merit of strengthening promoting blood circulation to remove blood stasis is arranged again.
The inventor is by to from May, 2002--and in February ,-2005 is to gastritis sufferer 165 people, gastric ulcer patient 145 people, dyspepsia patient 253 people, gastric cancer 82 people; Enteritis patient 280 people, trouble digestive tract cancer cercinoma prophase pathologic change (chronic atrophic gastritis, intestinal gland metaplasia, rectum hypertrophy, enteric epithelium atypical hyperplasia) patient 146 people, digestive tract cancer postoperative adjuvant therapy patient 120 people's clinical observation on the therapeutic effect the results are shown in Table 1.
Table 1: this pharmaceutical preparation observation of curative effect catalog of being correlated with
By Clinical analysis, prove that this pharmaceutical preparation is at treatment gastritis, gastric ulcer, enteritis, dyspepsia, digestive tract cancer cercinoma prophase pathologic change and digestive tract cancer operation back auxiliary treatment determined curative effect.
Claims (5)
1, a kind of have an invigorating the spleen and benefiting QI, promoting blood circulation and detoxication, circulation of qi promoting remove the effect of painful abdominal mass, be used for gastritis, gastric ulcer, enteritis, dyspepsia, digestive tract cancer cercinoma prophase pathologic change and digestive tract cancer operation back auxiliary treatment, can improve significantly that flatulence, liver pain, upper abdomen dull pain, belch, appetite are poor, the pharmaceutical preparation of spiritlessness and weakness clinical symptoms, its prescription is:
Prescription 1:
Radix Ginseng 50g～150g Herba Rabdosiae glaucocalycis 1000g～3000g Fructus Aurantii 150g～350g
Prescription 2:
Radix Codonopsis 50g～2000g Herba Rabdosiae glaucocalycis 1000g～3000g Fructus Aurantii 150g～350g
Prescription 3:
Radix Panacis Quinquefolii 50g～200g Herba Rabdosiae glaucocalycis 1000g～3000g Fructus Aurantii 150g～350g
The Radix Ginseng of wherein filling a prescription in 1 comprises wild ginseng, Radix Ginseng Rubra, Korean Ginseng.
2, pharmaceutical preparation according to claim 1 is characterized in that the preparation method of said pharmaceutical preparation is:
Preparation method 1: above three flavors, prescription Radix Ginseng or the fill a prescription Radix Codonopsis in 2 or the Radix Panacis Quinquefolii powder of filling a prescription in 3 in 1 is broken into fine powder, and be standby; Herba Rabdosiae glaucocalycis is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Fructus Aurantii is ground into coarse powder and adds 5--10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered, and filtrate is mixed with above-mentioned filtrate, is concentrated into the cream that relative density is 1.10-1.20, and drying under reduced pressure adds fine powder, mixing, promptly.
Preparation method 2: above three flavors, prescription Radix Ginseng or the fill a prescription Radix Codonopsis in 2 or the Radix Panacis Quinquefolii powder of filling a prescription in 3 in 1 is broken into coarse powder, adds 5--10 times of water gaging and decocts secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Herba Rabdosiae glaucocalycis is ground into coarse powder and adds 5--10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Fructus Aurantii is ground into coarse powder and adds 5--10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered, and filtrate is mixed with above-mentioned filtrate, is concentrated into the cream that relative density is 1.10-1.20, and drying under reduced pressure adds appropriate amount of auxiliary materials, mixing, promptly.
Preparation method 3: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or fill a prescription the Radix Panacis Quinquefolii 3 in of prescription in 1 is ground into coarse powder with Herba Rabdosiae glaucocalycis with Fructus Aurantii and adds 5-10 times of water gaging and decoct three times, each 1～3 hour, collecting decoction, filter, filtrate is concentrated into the cream that relative density is 1.10-1.20, drying under reduced pressure, mixing, promptly.
Preparation method 4: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or the Radix Panacis Quinquefolii powder of filling a prescription 3 in of prescription in 1 is broken into coarse powder, add 30%～95% ethanol 5-10 and doubly measure reflux, extract, or percolation 1--3 time, each 3 hours, merge extractive liquid, or percolate, filter, decompression filtrate recycling ethanol, the cream that is concentrated into relative density and is 1.30-1.38 is standby; Herba Rabdosiae glaucocalycis is ground into coarse powder and adds 5-10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered filtrate for later use; Fructus Aurantii is ground into coarse powder and adds 5--10 times of water gaging decoction secondary, and each 1--3 hour, collecting decoction filtered, and filtrate is mixed with above-mentioned filtrate, is concentrated into the cream that relative density is 1.10-1.20, drying under reduced pressure, and mixing, promptly
Preparation method 5: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or the Radix Panacis Quinquefolii powder of filling a prescription 3 in of prescription in 1 is broken into coarse powder, add 30%～95% ethanol 5-10 and doubly measure reflux, extract, or percolation 1--3 time, each 3 hours, merge extractive liquid, or percolate, filter, decompression filtrate recycling ethanol, the cream that is concentrated into relative density and is 1.30-1.38 is standby; Herba Rabdosiae glaucocalycis and Fructus Aurantii are ground into coarse powder and decoct with water 1--3 time, and each 1～3 hour, collecting decoction filtered, and filtrate is concentrated into the cream that relative density is 1.10-1.20, drying under reduced pressure, and mixing, promptly
Preparation method 6: above three flavors, Radix Ginseng or fill a prescription Radix Codonopsis 2 in or fill a prescription the Radix Panacis Quinquefolii powder 3 in of prescription in 1 is broken into coarse powder and adds 30%～95% ethanol 5-10 with Herba Rabdosiae glaucocalycis with Fructus Aurantii and doubly measure reflux, extract, or percolation 1--3 time, each 3 hours, merge extractive liquid, or percolate filter decompression filtrate recycling ethanol, be concentrated into the cream that relative density is 1.30-1.38, drying under reduced pressure, mixing, promptly.
3, pharmaceutical preparation according to claim 1 and 2 is characterized in that said medicine is: tablet, capsule, granule, pill, pellet, powder, mixture, soft capsule, drop pill, unguentum.
4, according to claim 1 or 2 or 3 described pharmaceutical preparatioies, it is characterized in that said pharmaceutical preparation has the function of invigorating the spleen and benefiting QI, promoting blood circulation and detoxication, be used for gastritis, gastric ulcer, colitis, cancerous protuberance cercinoma prophase pathologic change and the postoperative auxiliary treatment of cancerous protuberance.
5, the crude drug in the above pharmaceutical preparation should be country legal drug standard or corresponding medicinal standard.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510076815 CN1709421A (en) | 2005-06-17 | 2005-06-17 | Medicinal formulation for preventing and treating stomach and digestive tract diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510076815 CN1709421A (en) | 2005-06-17 | 2005-06-17 | Medicinal formulation for preventing and treating stomach and digestive tract diseases |
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| CN1709421A true CN1709421A (en) | 2005-12-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510076815 Pending CN1709421A (en) | 2005-06-17 | 2005-06-17 | Medicinal formulation for preventing and treating stomach and digestive tract diseases |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689181A (en) * | 2015-04-05 | 2015-06-10 | 李孟平 | Traditional Chinese medicine composition for treating spleen-vacuity and phlegm-damp type esophagus cancer |
| CN106581236A (en) * | 2016-12-21 | 2017-04-26 | 杭州胡庆余堂药业有限公司 | Medicinal composition for promoting gastric motility, and preparation method and application thereof |
| CN107115473A (en) * | 2017-05-08 | 2017-09-01 | 山东省交通医院 | A kind of pharmaceutical composition for treating gastritis |
| CN107362220A (en) * | 2017-08-02 | 2017-11-21 | 杭州胡庆余堂药业有限公司 | A kind of application of pharmaceutical composition in the Chinese medicine preparation for preparing treatment functional dyspepsia FD |
-
2005
- 2005-06-17 CN CN 200510076815 patent/CN1709421A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689181A (en) * | 2015-04-05 | 2015-06-10 | 李孟平 | Traditional Chinese medicine composition for treating spleen-vacuity and phlegm-damp type esophagus cancer |
| CN106581236A (en) * | 2016-12-21 | 2017-04-26 | 杭州胡庆余堂药业有限公司 | Medicinal composition for promoting gastric motility, and preparation method and application thereof |
| CN107115473A (en) * | 2017-05-08 | 2017-09-01 | 山东省交通医院 | A kind of pharmaceutical composition for treating gastritis |
| CN107362220A (en) * | 2017-08-02 | 2017-11-21 | 杭州胡庆余堂药业有限公司 | A kind of application of pharmaceutical composition in the Chinese medicine preparation for preparing treatment functional dyspepsia FD |
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