CN1709384A - Ovarium-nourishing capsule for regulating female incretion and its preparing method - Google Patents

Ovarium-nourishing capsule for regulating female incretion and its preparing method Download PDF

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CN1709384A
CN1709384A CN 200510040753 CN200510040753A CN1709384A CN 1709384 A CN1709384 A CN 1709384A CN 200510040753 CN200510040753 CN 200510040753 CN 200510040753 A CN200510040753 A CN 200510040753A CN 1709384 A CN1709384 A CN 1709384A
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extract
isoflavone
content
alpha
linolenic acid
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白新鹏
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Abstract

The present invention relates to an Yangchao capsule preparation for regulating female endocrine. Said Yangchao capsule preparation is made up by using compound plant isoflavone extracted from trifolium pretense, pueraria root and soybean, dioscin, polygonatum root extract, rubus berry extract, spiny jujube kernel extract, cinnamon bark extract, white peony root extract, poria extract, grape seed extract, ass-hide glue, pearl calcium and alpha-linolenic acid.

Description

Regulate foster nest capsule of female incretion and preparation method thereof
Technical field
The present invention relates to health product, specifically a kind ofly can regulate foster nest capsule of female incretion and preparation method thereof comprehensively.
Background technology
Plant isoflavone and Rhizoma Dioscoreae Shu Yu Suds glycosides are the sources of women's health, replenish plant isoflavone and Rhizoma Dioscoreae Shu Yu Suds glycosides and can warm up the foster nest in palace, and menopause is postponed in enriching yin and nourishing kidney, regulates female incretion, delaying female aging comprehensively.Soybean isoflavone is one of main phytoestrogen, now be widely used in the health food of delaying female aging, but the people of diabetes and metabolic arthritis gout is human consumption soybean or Semen Glycines (because of Han Piao Ling) in a large number, beans contains high heat, long-term eating easily got fat, and, a little less than the single additional soybean isoflavone effect, the adaptation population is less relatively, is difficult to bring into play the estrogenic effect of two-ways regulation.
Summary of the invention
The object of the present invention is to provide a kind of foster nest capsule of regulating female incretion and preparation method thereof, so that a kind of energy is comprehensive, the endocrine product of two-ways regulation for the women provides.
According to design provided by the present invention, the foster nest goods of the composite plant isoflavone of two-ways regulation female incretion and Rhizoma Dioscoreae Shu Yu Suds are by Herba Trifolii Pratentis comprehensively, the compound isoflavone of plant such as Radix Puerariae and Semen sojae atricolor, Rhizoma Dioscoreae Shu Yu Suds glycosides, Rhizoma Polygonati extract, Fructus Rubi extract, Semen Ziziphi Spinosae extract, Cortex Cinnamomi extract, Radix Paeoniae Alba extract, Poria extract, Semen Vitis viniferae extract, Colla Corii Asini, Margarita calcium, alpha-linolenic acids etc. are formulated, and the shared percentage by weight of each several part is: isoflavone content is the Rhizoma Dioscoreae extract 10-20% of 40% the compound isoflavone extract 10-50% of plant Shu Yu Suds glycosides content 20%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, procyanidin content is 95% Semen Vitis viniferae extract 1-8%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is 55% alpha-linolenic acid product 1-8%.
Wherein the extract specification of indication is meant the effective content of composition, the ratio extract of indication is as " 12: 1 Fructus Rubi extracts ", its implication is meant with 12 portions of Fructus Rubies extracts a effective ingredient, equally, " 10: 1 Rhizoma Polygonati extracts " are meant with 10 parts of Rhizoma Polygonatis and extract 1 part of effective component extracts, because the extract of different proportion, its effective ingredient is different, ratio is high more, content of effective is relatively just high more, and as extract 1 part of effective ingredient wherein with 100 portions of Fructus Rubies, we claim that this extract is 100: 1 a Fructus Rubi extract, relative 12: 1 Fructus Rubi extract of its purity wants high, down together.
The capsular preparation method of foster nest of above-mentioned adjusting female incretion, it is characterized in that, press the Herba Trifolii Pratentis extract 1-10% of isoflavone content 40%, the Radix Puerariae extract 10-20% of isoflavone content 40%, the Rhizoma Dioscoreae extract 10-20% of the soybean isoflavone 1-10% Shu Yu Suds glycosides content 20% of isoflavone content 40%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, the Semen Vitis viniferae extract 1-8% of procyanidin content 95%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is that the ratio of 55% d-linolenic acid product 1-8% adds each prescription, be crushed to about 100 orders, sieve with 100 purposes sieve, and in mixer, mixed 30-60 minute.
Isoflavone also can adopt complex form to prepare, its ratio is: isoflavone content is the Rhizoma Dioscoreae extract 1020% of 40% the compound isoflavone extract 10-50% of plant Shu Yu Suds glycosides content 20%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, procyanidin content is 95% Semen Vitis viniferae extract 1-8%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is 55% alpha-linolenic acid product 1-8%, or wherein the specification of Chinese medicine ingredients is by the extract effective content.
The capsular preparation method of foster nest of above-mentioned adjusting female incretion is: by fermentative Production is the Rhizoma Dioscoreae extract 10-20% of 40% composite plant isoflavone 10-50% Shu Yu Suds glycosides content 20%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, the Semen Vitis viniferae extract 1-8% of procyanidin content 95%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, the ratio of 55% alpha-linolenic acid 1-8% adds each prescription, be crushed to about 100 orders, sieve with 100 purposes sieve, and in mixer, mixed 30-60 minute.
Then, again with the granule of above-mentioned mix homogeneously at 60 ℃ of following dry disinfection 4-8 hours, packing gets product.
Wherein, described composite plant isoflavone is to be raw material with Herba Trifolii Pratentis, Radix Puerariae and Semen sojae atricolor respectively, utilize existing processing technique to be processed into separately extract earlier, then according to by the Herba Trifolii Pratentis extract 1-10% of isoflavone content 40%, the Radix Puerariae extract 10-20% of isoflavone content 40%, composite the forming of soybean isoflavone 1-10% of isoflavone content 40%.
The composite plant isoflavone is that primary raw material carries out biofermentation with mixed plant seeds such as Herba Trifolii Pratentis, Semen sojae atricolor, Radix Puerariae, Semen Sesamis also, extracts to contain multiple bioactive composite plant isoflavone.
The extracting method of extract adopts microwave extraction: the ethanol with 60%, and solid-to-liquid ratio 1: 10, when system temperature was no more than 60 ℃, batch process 3 times reached more than 96% the leaching rate of plant seed total isoflavone.
The present invention's prescription also has following characteristics except the compound isoflavone of the plant that comprehensive adjusting female incretion is arranged:
1, biological fermentation process is produced compound isoflavone and is had higher biological activity, and it has Kang Zhong activity, the estrogenic effect of performance two-ways regulation.
2, Rhizoma Dioscoreae Shu Yu Suds glycosides contains mannose, choline, aminoacid, glycoprotein, amylase etc.Have spleen reinforcing, support lung, the kidney tonifying arresting seminal emission, tonify deficiency removes cold and heat gas, invigorating the spleen and replenishing QI power, longue meat is obeyed normal hearing and eyesight for a long time, kidney tonifying gas, strengthening the spleen and stomach, stopping leak dysentery, the saliva that reduces phlegm, the effect of profit fur.
3, Rhizoma Polygonati has boosting qi and nourishing yin, spleen invigorating, lung moistening, the effect of kidney tonifying.
4, Margarita calcium, the calcium that additional needed by human body is wanted can improve simultaneously the osteoporosis symptom that female aging causes, the effect of beauty treatment.
5, Fructus Rubi extract, Semen Ziziphi Spinosae extract, Cortex Cinnamomi extract, Radix Paeoniae Alba extract, Poria extract, Semen Vitis viniferae extract etc., effectively synergistic activation recovers women's ovarian function, promotes endocrine balance.
6, Colla Corii Asini, alpha-linolenic acid etc. can blood fat reducing, blood pressure, diuretic, improve effects such as sleep, relieving constipation.
Foster nest goods of the present invention after testing, the content of functional component is as follows:
The compound isoflavone of plant 〉=8%
Rhizoma Dioscoreae Shu Yu Suds glycosides 〉=3%
The compound isoflavone of the plant of this product is mixed plant seed fermentation products such as the highest Herba Trifolii Pratentis (redclover) of the natural isoflavone content of extraction, Semen sojae atricolor, Radix Puerariae, Semen Sesami, contain four kinds of isostatic plant isoflavone: genistein Genistein (estrogen activity is the highest), lignin isoflavone Daidzein, Biochanin A, xanthin isoflavone Formononetin; This product isoflavone content is 2~3 times of general commercially available soybean isoflavone up to 60mg: what every foster nest capsule contained 60mg removes the active isoflavone of candy body, and general Semen sojae atricolor or Semen Glycines isoflavone product only contain 25~35mg.Can reach every day standard recommendation intake (40~70mg) as long as replenish a foster nest capsule every day.
Any edible per capita of this product, the people of diabetes and metabolic arthritis gout is human consumption soybean or Semen Glycines (because of containing fast Ling) in a large number, and any edible per capita of Herba Trifolii Pratentis.This product does not almost have heat, can not get fat.Beans contains high heat, and long-term eating easily got fat! Herba Trifolii Pratentis does not almost have heat, can feel at ease for a long time to take.This product selects for use 100% natural plants non-genomic to transform food (Non-G.M.O.), report shows according to toxicity test, the edible above Herba Trifolii Pratentis isoflavone of 3000mg that surpasses of per kilogram weight just has safe doubt, just the foster nest capsule of at every turn taking more than 2500 with 50 kilograms adult just has safe doubt, this product action temperature and, pure natural plant extraction is just as the food of fruit or concentrated fruit juice, be not medicine, can feel at ease for a long time to eat.This product also is rich in the necessary fatty acid linoleic acid plus linolenic acid of human body, and meets the required ratio of body metabolism process, and other products does not then contain this constituents.
The specific embodiment
This product is by the Rhizoma Dioscoreae extract 10-20% of the compound isoflavone 10-50% of the plant of isoflavone content 40% Shu Yu Suds glycosides content 20%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, the Semen Vitis viniferae extract 1-8% of procyanidin content 95%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is 55% composite the forming of alpha-linolenic acid product 1-8%.
The compound isoflavone of various plants also can be used the method production of fermentation, and its technological process is: 1, natural wild plant screening; 2, pretreatment: remove impurity, deironing, section, drying, pulverizing; 3, proportioning raw materials mix homogeneously; 4, medium preparation; 5, microbial enzyme fermentation; 6, extract: utilize microwave extraction, 50-80 ℃, each 1-2 minute; 7, the separation of total isoflavone: filtrate remove impurity, concentrated with the low pole macroporous resin enrichment; 8, eluting separates; 9, concentrate drying; 10, condensing crystallizing; 11, the compound isoflavone product of plant.
The compound isoflavone of so-called biological activity plant is meant that we are that primary raw material carries out biofermentation with mixed plant seeds such as Herba Trifolii Pratentis, Semen sojae atricolor, Radix Puerariae, Semen Sesamis, extract contains multiple biological activity isoflavone, with the plant of fermentative Production compound different be the complex of isoflavone, therefore compound isoflavone has higher biological activity.
The extracting method of said extracted thing can adopt microwave extraction, utilize microwave radiation can improve extraction efficiency, shorten extraction time, reduce and extract temperature, extraction ratio can reach more than 90% in 10 minutes, the optimal conditions of microwave extraction active ingredients of plants is: the ethanol with 60%, and solid-to-liquid ratio 1: 10 is when system temperature is no more than 60 ℃, batch process 3 times, the leaching rate of plant seed total isoflavone is reached more than 96%, and the general hot dipping of its efficient is carried greatly and being improved, and it is lower to extract temperature.
Formulation Example of the present invention:
Example one, 1, Herba Trifolii Pratentis 20%, Radix Puerariae 60% and Semen sojae atricolor 20% are through screening; 2, pretreatment: Herba Trifolii Pratentis, Radix Puerariae and Semen sojae atricolor are carried out remove impurity, deironing, section, drying, pulverizing; 3, mix homogeneously; 4, medium preparation; 5, microbial enzyme fermentation; 6, extract: utilize microwave extraction, 50-80 ℃, each 1-2 minute; 7, the separation of total isoflavone: filtrate remove impurity, concentrated with the low pole macroporous resin enrichment; 8, eluting separates; 9, concentrate drying; 10, condensing crystallizing; 11, the compound isoflavone product of plant.The specific operation process of these operations, the technical parameter that relates to are prior art, can not repeat them here referring to relevant textbook.
Then the Rhizoma Dioscoreae extract 15% of the compound isoflavone 25% Shu Yu Suds glycosides content 20% of the plant of isoflavone 40%, 10: 1 Rhizoma Polygonati extract 5%, 12: 1 Fructus Rubi extract 5%, 10: 1 Semen Ziziphi Spinosae extract 5%, 6: 1 Cortex Cinnamomi extract 5%, 8: 1 Radix Paeoniae Alba extract 5%, 10: 1 Poria extract 5%, the Semen Vitis viniferae extract 5% of procyanidin content 95%, Colla Corii Asini 10%, Margarita calcium 10%, alpha-linolenic acid content is 55% alpha-linolenic acid product 5% composite mixing 90 minutes, granulate, 60 ℃ were descended dry 4-8 hour, fill by 0.3 gram/grain, irradiation 12 hours is bottled according to a conventional method again, make finished product after the check.
Example two, preparation technology is with example one, different is the addition of each composition, is specially: the Herba Trifolii Pratentis extract 5% of pressing isoflavone content 40%, the Radix Puerariae extract 20% of isoflavone content 40%, the Rhizoma Dioscoreae extract 10% of the soybean isoflavone 5% Shu Yu Suds glycosides content 20% of isoflavone content 40%, 10: 1 Rhizoma Polygonati extract 10%, 12: 1 Fructus Rubi extract 10%, Semen Ziziphi Spinosae extract 5% in 10: 1,6: 1 Cortex Cinnamomi extract 5%, 8: 1 Radix Paeoniae Alba extract 5%, 10: 1 Poria extract 5%, the Semen Vitis viniferae extract 5% of procyanidin content 95%, Colla Corii Asini 5%, Margarita calcium 5%, alpha-linolenic acid content is 55% alpha-linolenic acid product 5%.
Example three, preparation technology is with example one, different is the addition of each composition, is specially: the Herba Trifolii Pratentis extract 1% of pressing isoflavone content 40%, the Radix Puerariae extract 25% of isoflavone content 40%, the Rhizoma Dioscoreae extract 15% of the soybean isoflavone 4% Shu Yu Suds glycosides content 20% of isoflavone content 40%, 10: 1 Rhizoma Polygonati extract 10%, 12: 1 Fructus Rubi extract 5%, Semen Ziziphi Spinosae extract 5% in 10: 1,6: 1 Cortex Cinnamomi extract 5%, 8: 1 Radix Paeoniae Alba extract 5%, 10: 1 Poria extract 5%, the Semen Vitis viniferae extract 5% of procyanidin content 95%, Colla Corii Asini 5%, Margarita calcium 5%, alpha-linolenic acid content is 55% alpha-linolenic acid product 5%.

Claims (8)

1, a kind of foster nest capsule of regulating female incretion, it is characterized in that, main Herba Trifolii Pratentis extract 1-10% by isoflavone content 40%, the Radix Puerariae extract 10-20% of isoflavone content 40%, the Rhizoma Dioscoreae Shu Yu Suds glycosides 10-20% of the soybean isoflavone 1-10% Shu Yu Suds glycosides content 20% of isoflavone content 40%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, the Semen Vitis viniferae extract 1-8% of procyanidin content 95%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is 55% alpha-linolenic acid product 1-8% composition, and wherein the specification of Chinese medicine ingredients is by crude drug effective ingredient weight.
2, a kind of capsular preparation method of foster nest of regulating female incretion, it is characterized in that, press the Herba Trifolii Pratentis extract 1-10% of isoflavone content 40%, the Radix Puerariae extract 10-20% of isoflavone content 40%, the Rhizoma Dioscoreae Shu Yu Suds glycosides 10-20% of the soybean isoflavone 1-10% Shu Yu Suds glycosides content 20% of isoflavone content 40%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, the Semen Vitis viniferae extract 1-8% of procyanidin content 95%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is that the ratio of 55% alpha-linolenic acid product 1-8% adds each prescription, be crushed to about 100 orders, sieve with 100 purposes sieve, and in mixer, mixed 30-60 minute.
3, a kind of foster nest capsule of regulating female incretion, it is characterized in that, isoflavone content is the Rhizoma Dioscoreae extract 10-20% of 40% the compound isoflavone extract 10-50% of plant Shu Yu Suds glycosides content 20%, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, procyanidin content is 95% Semen Vitis viniferae extract 1-8%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is 55% alpha-linolenic acid product 1-8%, or wherein the specification of Chinese medicine ingredients is by the extract effective content.
4, a kind of capsular preparation method of foster nest of regulating female incretion, it is characterized in that, Rhizoma Dioscoreae Shu Yu Suds glycosides 10-20% by the composite plant isoflavone 10-50% Shu Yu Suds glycosides content 20% of the isoflavone content 40% of fermentative Production, 10: 1 Rhizoma Polygonati extract 1-10%, 12: 1 Fructus Rubi extract 1-10%, 10: 1 Semen Ziziphi Spinosae extract 1-10%, 6: 1 Cortex Cinnamomi extract 1-10%, 8: 1 Radix Paeoniae Alba extract 1-10%, 10: 1 Poria extract 1-10%, the Semen Vitis viniferae extract 1-8% of procyanidin content 95%, Colla Corii Asini 1-10%, Margarita calcium 1-10%, alpha-linolenic acid content is that the ratio of 55% alpha-linolenic acid product 1-8% adds each prescription, be crushed to about 100 orders, sieve with 100 purposes sieve, and in mixer, mixed 30-60 minute.
According to the capsular preparation method of foster nest of claim 2 or 4 described adjusting female incretions, it is characterized in that 5, at 60 ℃ of following dry disinfection 4-8 hours, packing got finished product with the granule of mix homogeneously.
6, according to the capsular preparation method of foster nest of the described adjusting female incretion of claim 4, it is characterized in that, the composite plant isoflavone is to be raw material with Herba Trifolii Pratentis, Radix Puerariae and Semen sojae atricolor respectively, utilize existing processing technique to be processed into separately extract earlier, then according to by the Herba Trifolii Pratentis extract 1-10% of isoflavone content 40%, the Radix Puerariae extract 10-20% of isoflavone content 40%, composite the forming of soybean isoflavone 1-10% of isoflavone content 40%.
7, according to the capsular preparation method of foster nest of the described adjusting female incretion of claim 4, it is characterized in that, the composite plant isoflavone is that primary raw material carries out biofermentation with mixed plant seeds such as Herba Trifolii Pratentis, Semen sojae atricolor, Radix Puerariae, Semen Sesamis also, extracts to contain multiple bioactive composite plant isoflavone.
8, according to the capsular preparation method of foster nest of claim 2 or 4 described adjusting female incretions, it is characterized in that, the extracting method of extract adopts microwave extraction: the ethanol with 60%, solid-to-liquid ratio 1: 10, when system temperature is no more than 60 ℃, batch process 3 times reaches more than 96% the leaching rate of plant seed total isoflavone.
CN 200510040753 2005-06-22 2005-06-22 Ovarium-nourishing capsule for regulating female incretion and its preparing method Pending CN1709384A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101422555B (en) * 2008-12-23 2011-01-05 武汉名实生物医药科技有限责任公司 Formulation capable of defaecating, adjusting qi and blood, improving internal secretion and preventing senescence and preparation method
CN101084968B (en) * 2007-06-27 2011-05-04 陕西盘龙制药集团有限公司 Health care food for increasing bone density
CN101239091B (en) * 2007-02-07 2011-07-06 上海华珠生物科技有限公司 Composition for preventing and controlling helicobacter pylori affection
CN102524638A (en) * 2010-12-31 2012-07-04 武汉一元堂生物科技有限公司 Health food formula applicable for ovary maintenance, endocrine modulation, anti-oxidation and senility delay of female and method for preparing health food formula
CN102846906A (en) * 2012-08-23 2013-01-02 深圳市安美信生物医药科技有限公司 Medicament for treating premature ovarian failure and preparation method thereof
CN105410937A (en) * 2015-06-23 2016-03-23 新疆环拓生物科技有限公司 Production process of beatifying calcium dispersible tablet

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101239091B (en) * 2007-02-07 2011-07-06 上海华珠生物科技有限公司 Composition for preventing and controlling helicobacter pylori affection
CN101084968B (en) * 2007-06-27 2011-05-04 陕西盘龙制药集团有限公司 Health care food for increasing bone density
CN101422555B (en) * 2008-12-23 2011-01-05 武汉名实生物医药科技有限责任公司 Formulation capable of defaecating, adjusting qi and blood, improving internal secretion and preventing senescence and preparation method
CN102524638A (en) * 2010-12-31 2012-07-04 武汉一元堂生物科技有限公司 Health food formula applicable for ovary maintenance, endocrine modulation, anti-oxidation and senility delay of female and method for preparing health food formula
CN102846906A (en) * 2012-08-23 2013-01-02 深圳市安美信生物医药科技有限公司 Medicament for treating premature ovarian failure and preparation method thereof
CN102846906B (en) * 2012-08-23 2014-08-20 深圳市安美信生物医药科技有限公司 Medicament for treating premature ovarian failure and preparation method thereof
CN105410937A (en) * 2015-06-23 2016-03-23 新疆环拓生物科技有限公司 Production process of beatifying calcium dispersible tablet

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