CN1676100A - Non-invasive laser blood glucose detector - Google Patents
Non-invasive laser blood glucose detector Download PDFInfo
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- CN1676100A CN1676100A CN 200510020410 CN200510020410A CN1676100A CN 1676100 A CN1676100 A CN 1676100A CN 200510020410 CN200510020410 CN 200510020410 CN 200510020410 A CN200510020410 A CN 200510020410A CN 1676100 A CN1676100 A CN 1676100A
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- laser
- blood glucose
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- modulation
- detector
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- 239000008280 blood Substances 0.000 title claims description 21
- 210000004369 blood Anatomy 0.000 title claims description 21
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims description 6
- 239000008103 glucose Substances 0.000 title claims description 6
- 238000001514 detection method Methods 0.000 claims abstract description 15
- 238000012545 processing Methods 0.000 claims abstract description 12
- 230000003287 optical effect Effects 0.000 claims abstract description 5
- 239000004065 semiconductor Substances 0.000 claims abstract description 5
- 238000012360 testing method Methods 0.000 claims description 5
- 238000005259 measurement Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000011088 calibration curve Methods 0.000 description 2
- 239000004973 liquid crystal related substance Substances 0.000 description 2
- 230000010287 polarization Effects 0.000 description 2
- 238000002306 biochemical method Methods 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The present invention relates to a non-invasive laser blood-sugar detection instrument. Said detection instrument is formed from optical system, laser modulation and compensation system and signal processing system. Said invention adopts semiconductor laser tube as light source, and said laser is passed through polarizer and finger to be tested, and passed through Faraday's coil and analyzer, finally a detector can be used for making detection. Said signal processing system is formed from signal detection portion, modulation, demodulation portion, frequency lock amplifier and dup microprocessor. Besides, said detection instrument also includes LCD display screen and computer interface.
Description
Technical field
The present invention relates to a kind of instrument of measuring blood sugar for human body content, it need not take blood sample, only needs people's finger is put into tester, can carry out the real-time non-invasive measurement of blood sugar content.
Background technology
At present, the method that the measurement of blood sugar for human body content is adopted usually all is to use the blood taking needle blood sampling, uses biochemical method (hospital's employing) or blood-sugar detecting instrument (individual adopts) to cooperate corresponding reagent paper to realize the detection of blood sugar content then.Yet, adopt these two kinds of method of testings all to lack real-time and be a kind of wound test of having, increased patient's misery; Simultaneously, the storage environment of reagent paper is very big to reagent paper influence, and except that the quality of reagent paper own, reagent paper is exposed in the air, makes moist, the contaminated test result that all can cause is inaccurate.
Summary of the invention
The purpose of this invention is to provide a kind of noinvasive, measure the instrument of blood sugar for human body content in real time, fast.
Technical scheme of the present invention is a kind of non-wound laser blood sugar detecting instrument of design, and detector is by optical system, Laser Modulation and bucking-out system, and signal processing system is formed.Adopt semiconductor laser tube 1 as light source, laser is detected by detector 6 at last by the polarizer 2, finger to be measured 3, through faraday's coil 4 and analyzer 5; The detected signal of detector enters the signal processing system of being made up of signal detection part 7, modulating/demodulating part 8, frequency locking amplifier 9 and single-chip microcomputer 10; Modulation and compensation that Single-chip Controlling faraday's coil power drive part 11 is realized laser; Finish the processing that detects data by signal processing system, testing result is shown by LCD display 13, and can be transferred to computer by computer interface 12.
In the above-mentioned human body laser blood sugar detecting instrument, signal detection part 7 adopts high speed integrated operational amplifier IC1A, IC1B, R1, R2, R3, R4, R5, C1, C2, compositions such as C3 and photoelectric sensor D1, and then by modulating/demodulating part 8, lock-in amplifier part 9 obtains the useful signal that detected, carry out A/D through single-chip microcomputer and convert digital signal to, simultaneously, pass through single-chip microcomputer, 11 pairs of light of control faraday's coil power drive part compensate, form closed loop, in addition monolithic with the digital signal that collects with reference to the calibration curve that is stored in the single-chip microcomputer, calculate blood sugar concentration, be presented on the liquid crystal display screen, single-chip microcomputer is also delivered to data computer interface part 12 and is done further processing for computer in addition.
Human body laser blood sugar detecting instrument involved in the present invention, have no wound, no pain, detection fast, characteristics such as convenient, detect and under human body normal physiological state, carry out fully, can realize human blood glucose concentration in body, real-time continuous monitoring.
Description of drawings
Fig. 1 forms sketch map for system structure
Fig. 2 is signal detection partial circuit figure
Wherein 1 is the semiconductor laser tube light source; 2 is the laser polarizer; 3 refer to for hands to be measured; 4 is faraday's coil; 5 is analyzer; 6 is detector; 7 is the signal detection part; 8 is the modulating/demodulating part; 9 is the frequency locking amplifier; 10 is single-chip microcomputer; 11 is faraday's coil power drive part; 12 is computer interface; 13 is LCD display.
The specific embodiment
Below in conjunction with accompanying drawing specific embodiments of the invention are further described.
System structure of the present invention is formed as shown in Figure 1, light source adopts the semiconductor laser tube 1 of red or infrared, the micropower of certain wavelength, take the power stability measure with laser power stability, laser beam is by the polarizer 2, the direction of the polarizer is adjusted to the output intensity maximum, then carry out the blood sugar concentration sampling by human finger 3, Faraday polarization apparatus (Faraday Rotator) 4 is used to provide system modulation and feedback compensation, and light beam is again by analyzer 5.The plane of polarization of two polarizers becomes 90 °, and end is a photodiode detector 6, and the voltage of its output is directly proportional with the light intensity that receives, and the voltage of its output is as the input of digital processing unit.
The signal that photodiode detects is through signal detection part 7, modulating/demodulating part 8 and 9 pretreatment of frequency locking amplifier, transfer to single-chip microcomputer 10 with A/D translation function, single-chip microcomputer 10 carries out special handling with the digital signal result who is changed, amplify through faraday's coil power drive part 11 again, drive Faraday compensator 4, thereby form closed loop.
Single-chip microcomputer 10 with reference to the calibration curve that is stored in the single-chip microcomputer, calculates blood sugar concentration with the digital signal that collects, is presented on the liquid crystal display screen 13, and test result can be sent to computer by computer interface 12.
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 200510020410 CN1676100A (en) | 2005-02-25 | 2005-02-25 | Non-invasive laser blood glucose detector |
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CN 200510020410 CN1676100A (en) | 2005-02-25 | 2005-02-25 | Non-invasive laser blood glucose detector |
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CN1676100A true CN1676100A (en) | 2005-10-05 |
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CN 200510020410 Pending CN1676100A (en) | 2005-02-25 | 2005-02-25 | Non-invasive laser blood glucose detector |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010121413A1 (en) * | 2009-04-21 | 2010-10-28 | 中山大学 | Non-invasive blood glucose detection and monitoring device using impulse response and method therefor |
CN104013411A (en) * | 2014-05-15 | 2014-09-03 | 哈尔滨工业大学 | Transmission type noninvasive blood sugar detection device |
CN107693025A (en) * | 2017-09-22 | 2018-02-16 | 郜键 | A kind of non-blood sampling formula blood glucose meter of laser imaging |
CN114159054A (en) * | 2021-11-29 | 2022-03-11 | 惠州壹相科技有限公司 | Noninvasive blood glucose monitoring system |
-
2005
- 2005-02-25 CN CN 200510020410 patent/CN1676100A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010121413A1 (en) * | 2009-04-21 | 2010-10-28 | 中山大学 | Non-invasive blood glucose detection and monitoring device using impulse response and method therefor |
CN104013411A (en) * | 2014-05-15 | 2014-09-03 | 哈尔滨工业大学 | Transmission type noninvasive blood sugar detection device |
CN107693025A (en) * | 2017-09-22 | 2018-02-16 | 郜键 | A kind of non-blood sampling formula blood glucose meter of laser imaging |
CN114159054A (en) * | 2021-11-29 | 2022-03-11 | 惠州壹相科技有限公司 | Noninvasive blood glucose monitoring system |
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