CN104013411A - Transmission type noninvasive blood sugar detection device - Google Patents
Transmission type noninvasive blood sugar detection device Download PDFInfo
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- CN104013411A CN104013411A CN201410205838.4A CN201410205838A CN104013411A CN 104013411 A CN104013411 A CN 104013411A CN 201410205838 A CN201410205838 A CN 201410205838A CN 104013411 A CN104013411 A CN 104013411A
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Abstract
The invention discloses a transmission type noninvasive blood sugar detection device which comprises an optical system, a blood sugar detection system and a computer. The optical system comprises a light source and a photoelectric detector. The blood sugar detection system comprises a signal processing module, a data transmission module and a data display module. Light emitted by the light source is reflected on human fingers, and detected and received by the photoelectric detector and converted into electrical signals after finger transmission. The signal processing module conducts amplifying and filtering on the electrical signals, and transmits the electrical signals to the computer. A mathematical model is established through a support vector machine regression method, and the computer computes out the blood sugar concentration value. According to the transmission type noninvasive blood sugar detection device, the blood sugar concentration is detected through a transmission way by the adoption of a single-wavelength and power-fixed near-infrared waveband laser; the blood sugar content of diabetic patients can be continuously detected in real time through the blood sugar detection system, and disposable test paper is no longer depended on, so that cross infection and environmental pollution caused by blood sampling are avoided, and pain caused by frequent blood sampling of the diabetic patients is avoided.
Description
Technical field
The invention belongs to blood sugar in diabetic patients Concentration Detection field, relate to a kind of transmission-type Woundless blood sugar checkout gear.
Background technology
Diabetes are a kind of serious, chronic, non-infectious, lifelong property diseases, along with social development, scientific and technological progress, living standard raising, life pattern change and social senilization, diabetes prevalence is rising with surprising rapidity year by year, and its mortality rate is only second to malignant tumor, cardiovascular and cerebrovascular disease.World Health Organization (WHO) (WHO) interrelated data shows, global diabetics has exceeded 3.66 hundred million, estimates double to the year two thousand thirty.Therefore are long-term and difficult tasks for the treatment of diabetes.
Compare with having wound detection and Wicresoft's two kinds of methods of detection, Woundless blood sugar detects the blood glucose that breaks traditions the bottleneck of wound detection method, has the realistic meaning of the following aspects:
1, patient no longer includes the misery of blood sampling, improves patient's quality of life;
Thereby 2, increase and measure number of times raising glycemic control degree of accuracy, reduce diabetic complication;
3, owing to not needing consumable goods, thereby can reduce measurement cost;
4, the closed loop system that makes to set up blood sugar test and injection of insulin becomes possibility;
5, detection technique can be used for reference the measurement of other liquid component.
The method that noinvasive detects comprises impedance method, counter ion electro-osmosis method, electrochemical method, microwave technology, tissue fluid acquisition method, human body fluid method, optical means etc.
At present, it is an advanced blood sugar test technology that Woundless blood sugar detects, and patient can detect at any time the variation of blood sugar concentration and keep on a diet or seek medical advice in time.Therefore, Woundless blood sugar detection technique has very large researching value and practical value.
Summary of the invention
For addressing the above problem, the object of the present invention is to provide a kind of transmission-type Woundless blood sugar checkout gear.
For achieving the above object, technical scheme of the present invention is:
A kind of transmission-type Woundless blood sugar checkout gear, includes optical system and system for detecting blood sugar and computer; Wherein, optical system includes light source and photodetector; System for detecting blood sugar includes signal processing module, data transmission module and data disaply moudle; Described signal processing module includes amplifying circuit, filter circuit and single-chip microcomputer; The illumination that light source sends is mapped to human finger, after finger transmission, detect and receive and be converted to the signal of telecommunication by photodetector, signal processing module carries out amplification filtering processing to this signal of telecommunication, transfer data to computer by data transmission module by microcontroller serial port, by a mathematical model, Computer calculates blood glucose concentration value.
Further, described light source is semiconductor laser diode, and this semiconductor laser diode sends the laser irradiation finger of a branch of constant power, fixed wave length.
Further, described data transmission module is a wireless transmission transceiver module, and described data disaply moudle includes liquid crystal display circuit.
Further, also include key-press module and USB memory module, detect blood sugar concentration result and curve and shown by data disaply moudle and historical blood glucose concentration value is stored by USB memory module, by wireless transmission method, patient's blood glucose concentration value is transferred to insulin pump control system.
Another technical scheme of the present invention is:
A detection method for transmission-type Woundless blood sugar checkout gear, comprises the steps:
By semiconductor laser diode, as light source, the single wavelength laser that sends constant power irradiates patient's hands and refers to;
Photodetector is to detecting and receive and be converted to the signal of telecommunication through the incident illumination of finger transmission;
Signal processing module carries out after amplification filtering the ultra-weak electronic signal being detected, and through A/D, conversion enters single-chip computer control system;
Single-chip computer control system transfers data to computer by microcontroller serial port, is gone out blood glucose concentration value and is drawn blood sugar concentration change curve by calculated with mathematical model;
Data disaply moudle is to detecting blood sugar concentration result and change curve shows and historical blood glucose concentration value is stored.
Compared to prior art, the present invention utilizes single wavelength (1310nm), constant power near infrared band laser, carry out blood sugar concentration detection by transmission mode, system for detecting blood sugar can detect the blood sugar content of diabetics continuously in real time, and by wireless transmission method, patient's blood glucose concentration value is transferred to insulin pump control system, no longer rely on disposable reagent paper, avoided the cross infection and the environmental pollution that cause because of blood sampling, avoid the misery of the frequent blood sampling of diabetics.
Brief description of the drawings
Fig. 1 is theory structure block diagram of the present invention.
Fig. 2 is module frame chart of the present invention.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
Shown in Fig. 1, Fig. 2, transmission-type Woundless blood sugar checkout gear of the present invention includes optical system and system for detecting blood sugar; Wherein, optical system includes light source and photodetector; System for detecting blood sugar includes signal processing module, data transmission module and data disaply moudle; Described signal processing module includes amplifying circuit, filter circuit and single-chip microcomputer.The embodiment of the present invention adopts semiconductor laser diode as light source, semiconductor laser diode sends the laser irradiation of a branch of constant power, fixed wave length (1310nm) to human finger, incident illumination, after human body transmission, is detected and is received and be converted to the signal of telecommunication by photodetector.Detect faint measured signal by photoelectric detector, enter system for detecting blood sugar, by the amplification filtering processing of signal processing module settling signal, the A/D that is completed measured signal by data transmission module changes, and transfer data to computer by microcontroller serial port, utilizing before mathematical model carries out quantitative analysis, first adopt two kinds of methods of Multiscale Wavelet Decomposition and principal component analysis to carry out information retrieval twice to data, the data volume of mathematical model is set up in a large amount of reductions, utilize the support vector machine Return Law to carry out mathematical modeling, calculate blood glucose concentration value and draw blood sugar concentration change curve, detecting blood sugar concentration result and curve is shown by LCD data disaply moudle and historical blood glucose concentration value is stored, by wireless transmission method, patient's blood glucose concentration value is transferred to insulin pump control system.
Shown in Fig. 2, in example of the present invention, described data transmission module is a wireless transmission transceiver module, described data disaply moudle includes liquid crystal display circuit, transmission-type Woundless blood sugar checkout gear of the present invention is also provided with key-press module and USB memory module, described wireless transmitter module has the features such as transfer rate is high, low in energy consumption, and the blood sugar content value of the diabetics that blood sugar test module detects can be transferred to insulin pump control system by wireless transmission method; Control button and select module to realize the switching on and shutting down of system for detecting blood sugar, display mode and the functions such as system time are set, controls USB memory module and preserves blood sugar test record.
The detection method of transmission-type Woundless blood sugar checkout gear of the present invention comprises the steps:
(1) by semiconductor laser diode as light source, single wavelength (1310nm) laser irradiation patient hands that sends constant power refers to;
(2) photodetector is to detecting and receive and be converted to the signal of telecommunication through the incident illumination of finger transmission;
(3) signal processing module carries out after amplification filtering the ultra-weak electronic signal being detected, and through A/D, conversion enters single-chip computer control system;
(4) single-chip computer control system transfers data to computer by microcontroller serial port, is gone out blood glucose concentration value and is drawn blood sugar concentration change curve by calculated with mathematical model;
(5) LCD data disaply moudle shows and historical blood glucose concentration value is stored detecting blood sugar concentration result and change curve.
The present invention creates and adopts the blood sugar content that transmission mode is realized continuously, real-time noinvasive detects diabetics, the present invention simultaneously considers the fault that blood sugar detection apparatus in use may occur, design perfect solution, improved the reliability and stability of system.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.
Claims (5)
1. a transmission-type Woundless blood sugar checkout gear, is characterized in that: include optical system and system for detecting blood sugar and computer; Wherein, optical system includes light source and photodetector; System for detecting blood sugar includes signal processing module, data transmission module and data disaply moudle; Described signal processing module includes amplifying circuit, filter circuit and single-chip microcomputer; The illumination that light source sends is mapped to human finger, after finger transmission, detect and receive and be converted to the signal of telecommunication by photodetector, signal processing module carries out amplification filtering processing to this signal of telecommunication, transfer data to computer by data transmission module by microcontroller serial port, set up mathematical model by the support vector machine Return Law, Computer calculates blood glucose concentration value.
2. transmission-type Woundless blood sugar checkout gear as claimed in claim 1, is characterized in that: described light source is semiconductor laser diode, and this semiconductor laser diode sends the laser irradiation finger of a branch of constant power, fixed wave length.
3. transmission-type Woundless blood sugar checkout gear as claimed in claim 2, is characterized in that: described data transmission module is a wireless transmission transceiver module, and described data disaply moudle includes liquid crystal display circuit.
4. transmission-type Woundless blood sugar checkout gear as claimed in claim 3, it is characterized in that: also include key-press module and USB memory module, detect blood sugar concentration result and curve and shown by data disaply moudle and historical blood glucose concentration value is stored by USB memory module, by wireless transmission method, patient's blood glucose concentration value is transferred to insulin pump control system.
5. a detection method for transmission-type Woundless blood sugar checkout gear, is characterized in that, comprises the steps:
By semiconductor laser diode, as light source, the single wavelength laser that sends constant power irradiates patient's hands and refers to;
Photodetector is to detecting and receive and be converted to the signal of telecommunication through the incident illumination of finger transmission;
Signal processing module carries out after amplification filtering the ultra-weak electronic signal being detected, and through A/D, conversion enters single-chip computer control system;
Single-chip computer control system transfers data to computer by microcontroller serial port, is gone out blood glucose concentration value and is drawn blood sugar concentration change curve by calculated with mathematical model;
Data disaply moudle is to detecting blood sugar concentration result and change curve shows and historical blood glucose concentration value is stored.
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Cited By (8)
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CN104367327A (en) * | 2014-11-12 | 2015-02-25 | 杭州欣安医疗科技有限公司 | Detecting device and method for detecting human body biochemical parameters based on near-infrared rays |
CN105590033A (en) * | 2016-02-24 | 2016-05-18 | 成都信汇聚源科技有限公司 | Blood glucose information collection processing method |
CN105942982A (en) * | 2016-06-01 | 2016-09-21 | 何雷 | Tumor predictor based on dynamic spectra |
CN106264555A (en) * | 2016-10-17 | 2017-01-04 | 南方科技大学 | blood sugar detector |
CN107360279A (en) * | 2017-09-05 | 2017-11-17 | 陈银芳 | A kind of mobile terminal with blood glucose measurement function |
CN110327058A (en) * | 2019-07-31 | 2019-10-15 | 清华大学 | A kind of non-invasive blood sugar instrument and blood sugar detecting method |
US11229383B2 (en) | 2014-08-25 | 2022-01-25 | California Institute Of Technology | Methods and systems for non-invasive measurement of blood glucose concentration by transmission of millimeter waves through human skin |
CN114699920A (en) * | 2022-04-15 | 2022-07-05 | 北京大学 | Electroosmosis pump and application thereof |
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Publication number | Priority date | Publication date | Assignee | Title |
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US11229383B2 (en) | 2014-08-25 | 2022-01-25 | California Institute Of Technology | Methods and systems for non-invasive measurement of blood glucose concentration by transmission of millimeter waves through human skin |
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CN107360279A (en) * | 2017-09-05 | 2017-11-17 | 陈银芳 | A kind of mobile terminal with blood glucose measurement function |
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Application publication date: 20140903 |