CN1634540A - 一种用于动物消化道疾病的兽药 - Google Patents
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Abstract
本发明公开了一种用于动物消化道疾病的兽药，其特征在于该兽药由下述重量份的中药成分组成：神曲、炒麦芽、炒山楂、苍术、厚朴、干姜、甘草、青皮、陈皮、枳壳、大黄、苦参、莱萌子。其制备方法是将上述中药经严格选购后晒干或烘干后，粉碎过80目筛，按每包400克，以双层塑料袋分装即可。本发明的用于动物消化道疾病的兽药，具有化痰、清热、消导、通腑、助消化、积食、破气宽肠的疗效，对由于精料过多，造成的胃肠积滞、料伤五攒、伤食泄泻等症有非常满意的疗效。本发明亦可用于其它动物的同病症的治疗。
Description
技术领域
本发明属中医药领域，涉及一种兽药，特别涉及一种用于动物消化道疾病的兽药。
背景技术
动物的消化道疾病是常见的疾病之一，在调查中发现，多数散养动物场、户，沿用传统的饲养模式，科学饲养水平不高，尤其是饲草的质和量满足不了动物的需要，仅依靠增加精饲料喂量，来追求高产量。结果造成消化道疾病的增加，同时引起了肢蹄病及代谢病(如四胃变位)的发生，造成巨大损失。常用的治疗的药物根据不同的病症：为排出前胃内容物保用缓泻止酵剂，如硫酸钠、酒精、鱼石脂或豆油；为加强前胃蠕动可投吐酒石酸锑钾和番木别丁，同时配合瘤胃按摩和牵引运动；当呈现酸中毒症状时可用葡萄糠盐水、碳酸氢钠、安那加静注；有时也用抗菌消炎药，如氯霉素、金霉素、黄连素、磺氨咪啶、人工盐等。但是这些药物治表不治根，只能解决短暂的疼痛，不能是本质上治愈。所以当前中医界人士都在研究一种能治疗动物消化道疾病的中药，但目前还没有人公开使用过。
发明内容
本发明目的是提供一种用于动物消化道疾病的兽药，该药能够对动物的消化道疾病有明显治疗的效果。
本发明的目的是通过以下技术方案实现的：
一种用于动物消化道疾病的兽药，其特征在于该兽药由下述重量份的中药成分组成：神曲55～65g、炒麦芽55～65g、炒山楂55～65g、苍术45～55g、厚朴15～25g、干姜10～20g、甘草15～25g、青皮15～25g、陈皮25～35g、枳壳35～45g、大黄15～25g、苦参45～55g、莱萌子35～45g。
其制备方法是将上述中药经严格选购后晒干或烘干后，粉碎过80目筛，按每包400克，以双层塑料袋分装即可。
本发明的用于动物消化道疾病的兽药，具有化痰、清热、消导、通腑、助消化、积食、破气宽肠的疗效，对由于精料过多，造成的胃肠积滞、料伤五攒、伤食泄泻等症有非常满意的疗效。本发明亦可用于其它动物的同病症的治疗。
具体实施方式
以下结合发明人给出的该兽药的药效学试验和急性和长期毒性试验以及具体实施例对本发明作进一步详细说明。
1.药效学试验
本发明配方中的神曲、炒麦芽、山楂内含多种酶、淀粉、维生素以及糖类、挥发油等物质，是中医消导剂中的最佳配伍之一。而苍术、陈皮、厚朴、甘草、干姜、这各方平胃散，善沾湿困脾胃，肚腹胀满，大便溏泻，腹痛不安等症，伍以大黄、枳壳、青皮、茉萌子、增强其活血化瘀，破气宽肠，调肝气，理胃气，除胀满，通胃腑之功效，从而达到鼓动消化道的活动与消化腺的分泌功能，起到化痰不助火，清热不伤阳，消导不耗气，通腑不伤津的疗效，苦参配巷术燥湿健腺杀虫止痒再辅以干姜、甘草、以保护脾胃、湿中散寒。
下表为对照组、小量组、中量组、大量组具体试验结果：
| 组别 | 用药量(g/天) | 实验牛(头) | 治愈率(％) | 备注 |
| 对照组 | 0 | 10 | 0 |
| 小量组 | 300 | 10 | 90 | 用药时间较长，总用药量大 |
| 中量组 | 400 | 10 | 100 | 用药期短，总用药量小 |
| 大量组 | 500 | 10 | 50 |
2.动物急性毒性试验
以动物能耐受的最大浓度(3g/ml)、0.8ml的药量一次灌胃小鼠各20只，雌雄各半，连续观察7天，未发生死亡。给药量为120g/kg体重，相当于临床用量的179.1倍。在观察期间，未发现动物有明显中毒症状。
3.动物长期毒性试验大鼠分别灌胃乳炎消5g/kg/d、15g/kg/d(相当于临床给药剂量的7.4、22.2倍)连续四个月，两剂量组大鼠药后的一般活动，精神状态、毛发、粪便等均未见明显异常。给药前后外周血象，包括红细胞、白细胞及分类、血红蛋白、红细胞压积均在正常范围内波动。对三项肝(SGPT、SGOT)、肾(尿素氮、肌酐)功能指标均未见明显影响。试验结束时，动物血清中总蛋白、白蛋白、碱性磷酸酶的含量与对照组相比无明显差异。心电图检查均未发现异常。各主要脏器肉眼检查未见明显肿大、充血、坏死等病理形态学变化。心、肝、脾、肺、肾、胸腺、肾上腺、子宫、睾丸的重量系数与对照组相比，无显著差异。病理组织学检查，均未见异常。以上结果说明乳炎消比较安全，在所试剂量范围内并无明显毒副作用。(原始资料保存在西北农林科技大学畜牧兽医院)。
4.具体实施例
实施例1：
该用于动物消化道疾病的兽药的最佳配制为：神曲60g、炒麦芽60g、炒山楂60g、苍术50g、厚朴20g、干姜15g、甘草20g、青皮20g、陈皮30g、枳壳40g、大黄20g、苦参50g、莱萌子40g。
其制备方法是将上述中药经严格选购后晒干或烘干后，粉碎过80目筛，按每包400克，以双层塑料袋分装即可。
实施例2：
该用于动物消化道疾病的兽药的配制为：神曲55g、炒麦芽55g、炒山楂55g、苍术45g、厚朴15g、干姜10g、甘草15g、青皮15g、陈皮25g、枳壳35g、大黄15g、苦参45g、莱萌子35g。
其制备方法同实施例1。
实施例3：
该用于动物消化道疾病的兽药的配制为：神曲65g、炒麦芽65g、炒山楂65g、苍术55g、厚朴25g、干姜20g、甘草25g、青皮25g、陈皮35g、枳壳45g、大黄25g、苦参55g、莱萌子45g。
其制备方法同实施例1。
如果用于批量生产，可按上述配方成比例放大。
本发明的用于动物消化道疾病的兽药适用于以下症状：
病牛食欲、反刍减少，瘤胃蠕动音减弱，饲草能吃少许，尤其是厌食精料，粪便稀软，内混有未消化的精料渣，肚腹微胀，经1-2天后精神沉郁，奶量下降，有的病牛流涎、磨牙。
使用方法：每次400g内服，每日一次，直至痊愈。
具体病例：陈仓区八庙村田某一5岁黑白花动物，主诉：该牛产后20天，慢食已3天，仅吃少量草，见到精料后拒食。在当地用浓盐、促反刍等药，无明显效果。检查正常，一胃音弱，粪便溏稀，内含未消化的精料渣，流口水，精神沉郁。进一步问诊，得知该牛发病前每日喂精料约13kg，而日产奶量不足18kg。所以诊为精料过量引起的消化不良。用曲麦消食散3包，随后痊愈。
本发明的配方完全采用中药，成本低廉，使用方便，对由于精料过多，造成的胃肠积滞、料伤五攒、伤食泄泻等症有非常满意的疗效，使用过本发明的养牛户，家中都常备有该药，定期给动物服用，有效地防止了消化不良，肢蹄病及四胃病的发生，深受动物养殖户的青睐，本发明亦可用于其它动物的同病症的治疗。
Claims (2)
1.一种用于动物消化道疾病的兽药，其特征在于该兽药由下述重量份的中药成分组成：神曲55～65g、炒麦芽55～65g、炒山楂55～65g、苍术45～55g、厚朴15～25g、干姜10～20g、甘草15～25g、青皮15～25g、陈皮25～35g、枳壳35～45g、大黄15～25g、苦参45～55g、莱萌子35～45g。
2.如权利要求1所述的用于动物消化道疾病的兽药，其特征在于该中成药由下述重量份的中药成分组成：神曲60g、炒麦芽60g、炒山楂60g、苍术50g、厚朴20g、干姜15g、甘草20g、青皮20g、陈皮30g、枳壳40g、大黄20g、苦参50g、莱萌子40g。
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102755584A (zh) * | 2012-07-27 | 2012-10-31 | 郭再平 | 一种治疗家畜腹泻的药物 |
| CN103055280A (zh) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | 治疗家畜消化不良的纯中药组合物及其制备方法 |
| CN103948813A (zh) * | 2014-05-14 | 2014-07-30 | 山东新希望六和集团有限公司 | 一种用于治疗猫胃肠炎的中药组合物及其制备方法 |
| CN104351479A (zh) * | 2014-11-28 | 2015-02-18 | 张汉桥 | 肉牛饲料添加剂及其制备方法和使用方法 |
| CN104524352A (zh) * | 2014-12-01 | 2015-04-22 | 郑州后羿制药有限公司 | 一种用于动物健脾开胃的中药 |
| CN105497679A (zh) * | 2014-09-25 | 2016-04-20 | 谷三头 | 一种增强肉牛脾胃功能的中药配方 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755584A (zh) * | 2012-07-27 | 2012-10-31 | 郭再平 | 一种治疗家畜腹泻的药物 |
| CN103055280A (zh) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | 治疗家畜消化不良的纯中药组合物及其制备方法 |
| CN103055280B (zh) * | 2012-12-04 | 2014-12-03 | 青岛绿曼生物工程有限公司 | 治疗家畜消化不良的纯中药组合物及其制备方法 |
| CN103948813A (zh) * | 2014-05-14 | 2014-07-30 | 山东新希望六和集团有限公司 | 一种用于治疗猫胃肠炎的中药组合物及其制备方法 |
| CN105497679A (zh) * | 2014-09-25 | 2016-04-20 | 谷三头 | 一种增强肉牛脾胃功能的中药配方 |
| CN104351479A (zh) * | 2014-11-28 | 2015-02-18 | 张汉桥 | 肉牛饲料添加剂及其制备方法和使用方法 |
| CN104524352A (zh) * | 2014-12-01 | 2015-04-22 | 郑州后羿制药有限公司 | 一种用于动物健脾开胃的中药 |
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