CN1620886A - Ice-cream for preventing decayed tooth - Google Patents
Ice-cream for preventing decayed tooth Download PDFInfo
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- CN1620886A CN1620886A CN 200310115084 CN200310115084A CN1620886A CN 1620886 A CN1620886 A CN 1620886A CN 200310115084 CN200310115084 CN 200310115084 CN 200310115084 A CN200310115084 A CN 200310115084A CN 1620886 A CN1620886 A CN 1620886A
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- caries
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Abstract
The dental caries preventing ice cream consists of ice cream 1000 weight portions, dental caries resisting yolk immune globulin 0.1-50 weight portions, and dental caries resisting yolk immune globulin stabilizer and freeze protecting agent 0.5-35 weight portions. The production process of the dental caries preventing ice cream includes: compounding the materials of ice cream, dissolving dental caries resisting yolk immune globulin in small amount of cold boiled water, adding the stabilizer and the protecting agent into the compounded ice cream material via stirring, and freezing to obtain the dental caries preventing ice cream. The dental caries preventing ice cream has excellent dental caries preventing effect.
Description
Invention field
The present invention relates to a kind of ice cream, particularly a kind of ice cream that is used for kind of caries prevention.
Background technology
The cold drink ice cream is the frozen food that a kind of masses very like.Especially child and teenager except season in midwinter, almost are the things of snacks first-selection.Particularly hot summer days scorching, be so fond that will not let out of one's hand especially.
Gong Ying cold drink ice cream (popsicle) in the market, although be various in style, come in every shape, its nutrition all belongs to the food that high Icing Sugar, higher fatty acid, high protein, high heat are taken as the leading factor generally.Long-term too much eating, especially the fat partially child of body weight will impel adult's diseases such as causing arteriosclerosis, coronary heart disease, hypertension to take place prematurely.In addition, slow molten process and nutrient residual in oral cavity facing, dental groove, teeth space of cold drink ice cream in the oral cavity is again a large amount of breedings of cariogenic bacteria (distortion chain bacterium), and the condition that very is fit to is provided.Therefore, the children caries incidence rate is high, and except the incorrect reason of brushing teeth, the custom of long-term happiness food cold drink ice cream and sweet food also is one of major reason wherein.
In the cold drink articles of ice confectionery of existing listing, the adding Semen arachidis hypogaeae that has, Semen Sesami, chocolate increase palatability; The adding fruit that has, vegetable juice, carrot paste increase dietary fiber; The adding Chinese medicine Radix Ginseng that has, Rhizoma Gastrodiae, Fructus Lycii are with tonification.Adding vitamin that also has and Semen sojae atricolor, corn and other corn improve ice-cream nutritive proportion to replace wherein some composition.Use a kind of dental caries chicken yolk immunoglobulin but have not yet to see---be referred to as additive, make the cold drink ice cream have popsicle, articles of ice confectionery that prevention suppresses the cariogenic bacteria survival and reproduction effect in the oral cavity.
Summary of the invention
One object of the present invention is to disclose a kind of ice cream that is used for caries prevention; Another object of the present invention is a kind of method of ice cream that is used for caries prevention of open preparation.
Technical scheme of the present invention is:
A kind of ice cream that is used for caries prevention is made up of popsicle ice cream 1000 weight portions, dental caries Yolk immunoglobulin (Igy) 0.1-50 weight portion, dental caries Yolk immunoglobulin stabilizing agent and cryoprotective agent 0.5-35 weight portion.
Described popsicle ice cream can be any commercially available ice cream; Also can make with the following method: sucrose 14.5kg, whole milk powder 12kg, milk 20kg, butter 3kg, hydrogenated vegetable oil 1.5kg, fabaceous lecithin 0.25kg, egg yolk 0.1kg, Resina persicae 0.25kg join in 60 ℃ ± 2 ℃ water 44.5kg water and stir, and sterilize 30 minutes for 65-75 ℃.20-30Mpa homogenizing then is cooled to 40-45 ℃ and carries out leaving standstill in 4.5-5 hour aging, congeals under-4 to-5 ℃ of conditions, is common commercially available ice milk.
The stabilizing agent of described IgY and cryoprotective agent are a kind of in the following material or several: glycerol, Polyethylene Glycol (200-6000), sorbitol, mannitol, sodium carboxymethyl cellulose, hydroxyethyl-cellulose, sodium alginate, xanthan gum, angle fork thatch glue, gelatin, polysorbate fat.
Anti-dental caries IgY is that the yolk extraction the hen after the specific antigen immunity is laid eggs gets, and its safety and common egg are just the same.Its anti-dental caries effectiveness have Chinese Stomatologic Medical College, No.4 Military Medicine Univ., Hubei Tongji University School of Stomatology, biological cell teaching and research room of Shanghai Second Emdical University, Guangdong Zhongshan University School of Stomatology, Huaxi Medical Univ, University of Fuzhou's bio-engineering research etc. a large amount of experiment and the clinical confirmations of unit.
A kind of ice-cream preparation method that is used for caries prevention of the present invention is: after the popsicle icecream mix; before freezing; the IgY powder that desire is added dissolves with small amount of cold boiled water earlier; then with stabilizing agent; protective agent adds mixing and be thread under stirring movement to be poured in the popsicle icecream mix; stir, freezing by the temperature and time of general making popsicle ice cream regulation, promptly get dental caries cold drink ice cream popsicle.
The present invention is used for the ice cream of caries prevention, can be rapidly in and the Streptococcus mutans in the oral cavity, change the shortcomings and deficiencies that the ice cream popsicle easily causes dental caries, effect with excellent prevention dental caries.
Following experimental example further specifies the present invention.
Carry out the dental caries clinical trial in experimental example dental caries chicken yolk immunoglobulin (IgY) the adding ordinary milk ice cream
(1) sample preparation, the anti-tooth decay IgY ice milk
Contact cold drink company prepares the compound after ordinary milk ice cream 150kg wears out, and presses ten thousand of ice cream total amount/adding anti-tooth decay IgY and other stabilizing agent and protective agent, and abundant mixing, congeals promptly under-4～-5 ℃.
(2) the preliminary clinical trial of dental caries effect
Recruit volunteer 40 people, non-activity dental caries condition, oral conditions is general, no systemic disease, does not use antibiotic and anti-inflammation drugs in the recent period.Divide experimental group 20 people the experimenter, every day at the upper and lower noon is the heavy ice milk that contains the anti-tooth decay IgY composition of 80g of containing respectively; Matched group 20 people, the same upper and lower noon is the heavy conventional ice cream of 80g of containing respectively.Test period is 14 days (two week), respectively in acid buffer sampling outside experimenter's first labial teeth and position, first tooth cheek tongue top layer PBS PH6.8,0.07mol/L before and after the experiment, cultivate Streptococcus mutans after each 48 hours with BHIS culture medium anaerobism, calculate the molten several percentage rate of molten number of total anaerobe bacterium and Streptococcus mutans bacterium.The result:
Table 1, containing contain anti-tooth decay IgY composition ice milk subject oral cavity Streptococcus mutans
Account for the percentage rate of always detesting bacterium
The group mutans streptococcus order of magnitude (1g) accounts for total anaerobe (%)
Test preceding 4.35 56.75
Experiment two all backs 1.56 18.83
Table 2, containing ordinary milk ice cream subject oral cavity Streptococcus mutans account for the percentage rate of total anaerobe
The group mutans streptococcus order of magnitude (1g) accounts for total anaerobe (%)
Test preceding 4.03 52.04
Experiment two all backs 4.18 50.07
Containing contains in the ice cream subject oral cavity of anti-tooth decay IgY composition as seen from Table 1, tests the ratio that two all after strain streptococcus account for total anaerobe and all is obvious decline.With the experiment before compared notable difference (p＜0.05); In the ice-cream subject oral cavity of containing ordinary milk, test ratio and the preceding nothing of experiment significantly different (p＞0.05) that two all after strain streptococcus account for total anaerobe as seen from Table 2.
Following examples all can reach the effect of above-mentioned experimental example.
Embodiment 1
The preparation of ordinary milk ice cream: sucrose 14.5kg, whole milk powder 12kg, milk 20kg, butter 3kg, hydrogenated vegetable oil 1.5kg, fabaceous lecithin 0.25kg, egg yolk 0.1kg, Resina persicae 0.25kg join in 60 ℃ ± 2 ℃ water 44.5kg water and stir, and sterilize 30 minutes for 65-75 ℃.20-30Mpa homogenizing then is cooled to 40-45 ℃ and carries out leaving standstill in 4.5-5 hour aging, congeals under-4 to-5 ℃ of conditions, promptly.
Contain IgY preventing decayed tooth ice cream:
1, the above-mentioned ice milk raw material 100kg that leaves standstill after wearing out is standby;
2, get anti-tooth decay IgY lyophilized powder 15g, add the 250ml of eliminating cold for resuscitation water below 40 ℃ dissolving, in go into glycerol 100g mixing.Join then in the cold boiled water solution that is dissolved with the 15g sodium alginate and stir evenly
3, above-mentioned IgY mixed stability liquid is under agitation joined in the aging ice milk compound that finishes and continue to stir 5 minutes, the back is congealed promptly to get under-4～-5 ℃ of conditions and is contained IgY preventing decayed tooth ice cream
Embodiment 2
1, the ice milk 200kg compound for preparing after wearing out among the embodiment 1 is standby;
2, getting gelatin 200g, the boiled water 1000ml that heats dissolving and heating dissolves; Get heat boiled water (below 40 ℃) 5000ml dissolving of IgY300g, add PEG400 g and stir swallow, gelatin solution is poured into stirred evenly;
3, above-mentioned IgY mixed liquor under agitation is added in the ice milk compound of 200kg after aging, stirs evenly, start refrigeration machine, temperature is reduced to congeal under-4.5 ℃ promptly to get dental caries cold drink ice cream.
Embodiment 3
1, the ice milk compound 150kg after aging is standby in the preparation experiment example 1;
2, get sodium carboxymethyl cellulose 300g and add the 1000ml of eliminating cold for resuscitation water below 40 ℃ dissolving, after glycerol adding 500g stirs evenly, with sodium carboxymethyl cellulose fat melting liquid mixing; The suitable quantity of water solution and the last liquid that add 15gIgY stir evenly;
3, under agitation be thread and stirred 15 minutes in adding 1, start refrigeration machine and under-4 ℃ of conditions, congeal and promptly get the preventing decayed tooth order and drink ice cream 2.
Dental caries specific immune globulin antibody I mmunog-lobulin of yoikIgy in the foregoing description can sell for Zhejiang Etam Co., Ltd produces.
Claims (7)
1. an ice cream that is used for caries prevention is characterized in that being made up of popsicle ice cream 1000 weight portions, dental caries Yolk immunoglobulin 0.1-50 weight portion, dental caries Yolk immunoglobulin stabilizing agent and cryoprotective agent 0.5-35 weight portion.
2. the ice cream that is used for caries prevention as claimed in claim 1 is characterized in that the stabilizing agent of described IgY and cryoprotective agent are a kind of in the following material or several: glycerol, Polyethylene Glycol, sorbitol, mannitol, sodium carboxymethyl cellulose, hydroxyethyl-cellulose, sodium alginate, xanthan gum, angle fork thatch glue, gelatin, polysorbate fat.
3. the ice cream that is used for caries prevention as claimed in claim 2 is characterized in that the stabilizing agent of described IgY and cryoprotective agent Polyethylene Glycol are Macrogol 200-6000.
4. the ice cream that is used for caries prevention as claimed in claim 2 is characterized in that being made up of popsicle ice cream 1000 weight portions, dental caries Yolk immunoglobulin 0.15 weight portion, glycerol 1 weight portion, sodium alginate 0.15 weight portion.
5. the ice cream that is used for caries prevention as claimed in claim 2 is characterized in that being made up of popsicle ice cream 1000 weight portions, dental caries Yolk immunoglobulin 3 weight portions, gelatin 2 weight portions, Polyethylene Glycol 4 weight portions.
6. the ice cream that is used for caries prevention as claimed in claim 2 is characterized in that being made up of popsicle ice cream 1000 weight portions, dental caries Yolk immunoglobulin 0.1 weight portion, sodium carboxymethyl cellulose 2 weight portions, glycerol 3.3 weight portions.
7. as the described ice-cream preparation method that is used for caries prevention of claim 1-3; it is characterized in that this method is after the popsicle icecream mix; before freezing; the IgY powder that desire is added dissolves with small amount of cold boiled water earlier; with stabilizing agent, protective agent adds mixing and be thread under stirring movement to be poured in the popsicle icecream mix, stirs then; temperature and time by general making popsicle ice cream regulation is freezing, promptly gets dental caries cold drink ice cream.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310115084 CN1254187C (en) | 2003-11-27 | 2003-11-27 | Ice-cream for preventing decayed tooth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310115084 CN1254187C (en) | 2003-11-27 | 2003-11-27 | Ice-cream for preventing decayed tooth |
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| Publication Number | Publication Date |
|---|---|
| CN1620886A true CN1620886A (en) | 2005-06-01 |
| CN1254187C CN1254187C (en) | 2006-05-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200310115084 Expired - Fee Related CN1254187C (en) | 2003-11-27 | 2003-11-27 | Ice-cream for preventing decayed tooth |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103687499A (en) * | 2011-07-20 | 2014-03-26 | 奇华顿股份有限公司 | Compositions |
| CN104117062A (en) * | 2013-04-24 | 2014-10-29 | 杭州雅盛生物科技有限公司 | Preparation method of composite IgY against periodontal disease pathogenic bacteria |
| CN107183303A (en) * | 2017-06-14 | 2017-09-22 | 内蒙古蒙牛乳业（集团）股份有限公司 | Frozen and preparation method thereof |
| CN109198151A (en) * | 2018-08-23 | 2019-01-15 | 吉林大学 | A kind of ice-cream products and preparation method thereof rich in immunoglobulin |
-
2003
- 2003-11-27 CN CN 200310115084 patent/CN1254187C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103687499A (en) * | 2011-07-20 | 2014-03-26 | 奇华顿股份有限公司 | Compositions |
| CN104117062A (en) * | 2013-04-24 | 2014-10-29 | 杭州雅盛生物科技有限公司 | Preparation method of composite IgY against periodontal disease pathogenic bacteria |
| CN107183303A (en) * | 2017-06-14 | 2017-09-22 | 内蒙古蒙牛乳业（集团）股份有限公司 | Frozen and preparation method thereof |
| CN109198151A (en) * | 2018-08-23 | 2019-01-15 | 吉林大学 | A kind of ice-cream products and preparation method thereof rich in immunoglobulin |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1254187C (en) | 2006-05-03 |
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Granted publication date: 20060503 Termination date: 20101127 |