CN1588177A - Device for regulating light tweezers - Google Patents
Device for regulating light tweezers Download PDFInfo
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- CN1588177A CN1588177A CN 200410053443 CN200410053443A CN1588177A CN 1588177 A CN1588177 A CN 1588177A CN 200410053443 CN200410053443 CN 200410053443 CN 200410053443 A CN200410053443 A CN 200410053443A CN 1588177 A CN1588177 A CN 1588177A
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Abstract
The invention is a kind of regulable and controllable optical nippers, composed of a controllable three-regional concentric phase regulator and an objective lens arranged in the forward direction of incident parallel optical beams, where the regulator is composed from inside to outside of a centrally circular phase region, an internally annular phase region and an externally annular phase region, and the phase regulating surfaces are vertical to the optical axes, the internal and external diameters of the internally annular phase region are calculated and determined by the diffractive theory according to the distance that the material particle needs to be carried, the phases of the other two phase regions are the same, and the regulator are connected with a phase regulation controller. It has the characters of simple structure, operating convenience, and easy control of the carrying distance and direction of the material particle.
Description
Technical field
The present invention relates to the device of light tweezers, particularly a kind of adjustable smooth tweezers.Be mainly used in catching and carrying, particle classification, small force measurement, bio-science, Laser Processing and fields such as micromechanics and device of fine particle.
Technical background
The light tweezers are meant the instrument that utilizes light intensity gradient force and light scattering power to catch and handle molecule.Light beam is floated and the exploration of catching particulate can chase after contraryly to the seventies in 20th century, and still, real successful observation experiment was reported on English " optics letter " (0ptics letter) magazine in 1986.Since then, the light forceps technique develops by leaps and bounds becomes important scientific research technological means, and has promoted the fast development in many fields, for example catching and fields such as carrying, force measurement, micromechanics and micro element at molecule.At life science, the light tweezers are contactless with it, the essence of lossless detection has shown huge impetus especially.The particle size that the light tweezers are caught can be rigid particles from tens nanometers to tens micron, also can be soft material grains; Can be abiotic particle, also can be active somatic cell or virus.The light tweezers implementation that formerly has a kind of advanced person in the technology, utilize the Coherence Mode of two-beam to constitute regulatable smooth tweezers, and can rotate captive a plurality of particle continuously by the difference on the frequency or the optical path difference that change two-beam, experiment is published in (K.Dholakia et al on " nature " and " science " magazine, " Simultaneous micromanipulation in multiple planes using a selfreconstructing light beam; " Nature 2002,419,145, and " Creation andmanipulation of three-dimensional optically trapped structures; " Science2002,296, p1101-1103), have certain advantage, still come with some shortcomings although this kind constitutes the technology formerly of light tweezers:
1) adjustable smooth tweezers need two-beam to be concerned with, and form interference pattern and constitute the light tweezers, the apparatus structure complexity.
2) can not implement the handling process of particle continuously, the section start that can not be implemented in particle constantly forms new light tweezers and catches particle, is transported to destination, release particles then.
3) in the light tweezers device captive particle by the switch light source or adjust light intensity significantly and realize catching of particle and discharge that the control mode dirigibility is relatively poor.
Summary of the invention
The problem to be solved in the present invention has been to overcome the deficiency of above-mentioned technology formerly, and a kind of device of adjustable smooth tweezers is provided, and it has simple in structure, and Modulatory character is good, can realize characteristics such as particle handling process continuously.
Basic design of the present invention is:
The invention provides a kind of device of adjustable smooth tweezers.Utilize controlled three zones phase regulator with one heart, incident beam is carried out phase modulation (PM), modulated beam of light forms the light tweezers through converging of object lens, and the district catches particle in particle capture.The controlled three zones phase place of the interior annular phase region of phase regulator with one heart can be regulated continuously.In regulating continuously during annular phase region phase place, modulated beam of light converges the light tweezers that the back forms through object lens and moves along optical axis, shift to point of destination after the light tweezers slowly disappear release particles; Simultaneously can form new light tweezers and catch particle, and shift to point of destination, be called the particle release district again in another position of optical axis.The direction of motion of light tweezers is controlled by the phase change direction, and transport distance is determined by interior annular phase region internal diameter and external diameter.
Technical solution of the present invention is as follows:
A kind of device of adjustable smooth tweezers, its formation is to be equipped with controlled three zones phase regulator and object lens with one heart on the working direction of incident parallel beam, this concentric phase regulator in controlled three zones is from inside to outside by the central circular phase region, interior annular phase region and outer ring phase region constitute, and the phase adjusted face is vertical with optical axis, these the controlled three zones internal diameter and external diameter of the interior annular phase region of phase regulator are with one heart calculated definite according to the distance of material grains needs carrying by diffraction theory, the central circular phase region is identical with the phase place of outer ring phase region, and these controlled three zones phase regulator with one heart link to each other with a phase adjusted controller.
Described controlled three zones phase regulator with one heart are the transmission-type regulator, or reflective regulator.
Be equipped with spectroscope on the light incident direction of the concentric phase regulator in described controlled three zones, the controlled three zones modulated beam of light of phase regulators reflection are with one heart reflected by spectroscope, and object lens place on the emitting light path of spectroscope modulated beam of light.
Between described concentric phase regulator in controlled three zones and spectroscope, be equipped with quarter-wave plate, this quarter-wave plate is vertical with optical axis, and long axis direction and incident light polarization direction are at 45, spectroscope adopts polarization spectroscope, to the incident beam transmission, the light modulated through quarter-wave plate is then reflected.
Be mapped to controlled three zones with one heart during the modulation face of phase regulators when incident light is oblique, controlled three zones three phase regions of phase regulators with one heart are concentration ellipse, the method parallel line surface of long axis direction and incident beam.
The central circular phase region is identical to the phase place of light beam with the outer ring phase region.The controlled three zones interior annular phase region internal diameter and the external diameter of phase regulator with one heart can determine that specific practice is as follows according to diffraction theory:
Central circular phase region and outer ring phase region phase place are made as definite value , and the position of interior annular phase region is chosen to be +π mutually, according to diffraction theory, when the system value aperture is very little, can use paraxial approximate scalar diffraction theory; Other situations are used the approximate Vector Diffraction Theory based on Dybye, can calculate near the three-dimensional light distribution of focus, regulate different interior annular phase region internal diameter and external diameter value, can obtain two light intensity peak of three-dimensional light distribution, each peak is light tweezers of catching particle, and the peak-to-peak distance of light intensity is the transportable transport distance of particle.
The device of a kind of adjustable smooth tweezers of the present invention is structure as mentioned above, and in use, controlled three zones of incident beam directive are phase regulator with one heart, carries out phase modulation (PM), and modulated beam of light forms the light tweezers through converging of object lens, and the district catches particle in particle capture.Select suitable interior annular phase region internal diameter and external diameter according to diffraction theory, the transport distance of control particle.By the phase adjusted controller control controlled three zones with one heart the phase places of the interior annular phase region of phase regulators change continuously, forming catching and carrying of particle, the increase of phase place or reduce to change the direction of light tweezers carrying particle.
The work principle process is: when interior annular phase region phase place is , light tweezers are arranged, at this moment, the position of interior annular phase region increases continuously to +2k π (k is an integer) at , these light tweezers move to the object lens of optical system, behind the destination of certain distance, stop, and light intensity slowly is attenuated to zero.In this variation, in the destination away from object lens one side apart from destination transport distance place, i.e. particle carrying starting point, promptly the particle capture district forms new light intensity peak, constitutes new light tweezers, and moves to object lens.In the position of annular phase region increase continuously mutually, constantly form new light tweezers in particle carrying starting point, promptly new light intensity peak produces, and catches particle, is transported to the destination, i.e. particle release district, light intensity peak disappears, release particles.When the position of interior annular phase region reduced mutually continuously, handling process was identical, but the carrying direction of light tweezers is opposite.
When the concentric phase regulator in controlled three zones adopts reflective regulator, on the light incident direction of the concentric phase regulator in controlled three zones, be equipped with spectroscope, incident beam carries out phase modulation (PM) through the concentric phase regulator in controlled three zones of spectroscope directive to incident beam.The modulated beam of light of reflection by object lens focusing, forms the light tweezers through the spectroscope reflection.The phase adjusted controller is controlled the controlled three zones interior annular phase region phase place of phase regulator with one heart, realizes particle capture and carrying.
When incident beam is linearly polarized light beam, between concentric phase regulator in controlled three zones and spectroscope, be equipped with quarter-wave plate, the long axis direction of quarter-wave plate becomes an angle of 90 degrees with the incident light polarization direction; Spectroscope adopts polarization spectroscope, to the incident beam transmission, to seeing through the light modulated reflection of quarter-wave plate.Incident light is through polarization spectroscope and quarter-wave plate, change into circularly polarized light, reflected by the concentric phase regulator in controlled three zones, modulate, change into linearly polarized light through quarter-wave plate again, the polarization direction of the linearly polarized light of this moment is vertical with the polarization of incident light direction, so be polarized the spectroscope reflection.This kind scheme can improve the utilization factor of luminous energy.
Compare advantage of the present invention with technology formerly:
1) can implement the handling process of particle continuously, the trapping region that is implemented in particle constantly forms new light tweezers and catches particle, is transported to destination, release particles then;
2) control easily particle transport distance and the carrying direction;
3) this apparatus structure is simple, and is easy to operate, realizes robotization easily.
Description of drawings:
Fig. 1 is a principle of work synoptic diagram of the present invention.
Fig. 2 is the concentric phase regulator phase region distribution synoptic diagram in controlled three zones of the present invention.
Fig. 3 is embodiments of the invention 1 synoptic diagram.
Fig. 4 is embodiments of the invention 2 synoptic diagram.
Fig. 5 is embodiments of the invention 3 synoptic diagram.
Embodiment:
The invention will be further described below in conjunction with drawings and Examples.But should not limit protection scope of the present invention with this.
Fig. 1 is a principle of work synoptic diagram of the present invention.The formation of the device of the adjustable smooth tweezers of the present invention is: be equipped with controlled three zones phase regulator 1 and object lens 2 with one heart on the working direction of a parallel incident beam.These controlled three zones phase regulator 1 with one heart are made of central circular phase region 102, interior annular phase region 103 and outer ring phase region 101 from inside to outside, and the phase adjusted face is vertical with incident light axis, 3 expression light tweezers perform regions.Fig. 2 is the concentric phase regulator phase region distribution synoptic diagram in controlled three zones of the present invention, and the phase place of interior annular phase region 103 can be regulated continuously.In regulating continuously during annular phase region 103 phase places, modulated beam of light converges the back through object lens 2 and forms light tweezers in the perform region 3, and after shifting to point of destination along optical axis, the disappearance of light tweezers, release particles; Simultaneously can form new light tweezers and catch particle, shift to point of destination in another position of optical axis.Direction of motion can change by the phase change direction.Select suitable interior annular phase region 103 internal diameters and external diameter according to diffraction theory, can determine the transport distance of particle.
Detailed process is among the embodiment: the three zones radius of phase regulator 1 with one heart are less than or equal to the incident laser beam radius, and the controlled three zones central circular phase region 102 and outer ring phase region 101 phase places of phase regulator 1 with one heart are zero.When the phase place of interior annular phase region 103 is zero, focus place at object lens forms light tweezers, when phase place increases by zero, the light tweezers at focus place can move towards the object lens direction along optical axis, on away from the optical axis of object lens, form the new light tweezers of growth gradually simultaneously, begin to catch particle in the particle capture district, and move to the object lens direction.The phase place of interior annular phase region 103 reaches π, and two light tweezers capture abilities are identical.The phase place of annular phase region 103 in continue increasing descends near the light tweezers capture ability of object lens, at particle release district release particles, moves towards the object lens direction away from the light tweezers of object lens.When phase place reached 2 π, the light tweezers of nearly object lens disappeared.The phase place of annular phase region 103 can constantly be transported to the particle release district from the particle capture district with particle in increasing continuously.Annular phase region 103 in 4 controls of phase adjusted controller is realized the robotization of this process.In reducing, during the phase place of annular phase region 103, promptly change the carrying direction of particle, with particle from be transported to particle release district from the near particle capture district of object lens away from object lens.
Present embodiment as shown in Figure 3, reflective working method is adopted in controlled three zones with one heart phase regulators 1, controlled three zones are equipped with spectroscope 5 on the light incident direction of phase regulators 1 with one heart.The controlled three zones modulated beam of light of phase regulator 1 reflection are with one heart reflected by spectroscope 5, are equipped with object lens 2 on spectroscope modulated beam of light exit direction, and controlled three zones are associated with phase adjusted controller 4 on the phase regulator 1 with one heart.The concentric phase regulator 1 in controlled three zones adopts the programmable phase photomodulator in the present embodiment, (market can buy to be called for short PPM, position alpha region shape can be set according to instructions), phase adjusted controller 4 adopts computing machine, the concentric phase regulator 1 in controlled three zones also can utilize light phase modulation principle (for example, utilizing axial transportable catoptron) to develop voluntarily in the present embodiment.Select interior annular phase region internal diameter and external diameter according to diffraction theory, the transport distance of control particle.Use is, after 5 transmissions of incident beam process spectroscope, by phase regulators 1 reflection with one heart of controlled three zones.Modulated beam of light converges through object lens 2 after being reflected by spectroscope 5, forms regulation and control light tweezers zone 3.Computing machine 4 is according to the programmable phase photomodulator, is called for short the work of annular phase region 103 in the PPM control, increase or reduce in annular phase region 103 phase places, realize catching the particle in the light field, it is transported to the unloading of particle release district.
The structure of present embodiment as shown in Figure 4, in the present embodiment, incident beam is a linearly polarized light beam.Between concentric phase regulator 1 in controlled three zones and spectroscope 5, be equipped with quarter-wave plate 6; Spectroscope 5 adopts polarization spectroscope, to the incident beam transmission, to seeing through the light modulated reflection of quarter-wave plate 6.The programmable phase photomodulator is still adopted in controlled three zones phase regulator 1 with one heart, and phase adjusted controller 4 adopts computing machine.Incident light is through polarization spectroscope 5 and quarter-wave plate 6, change into circularly polarized light, reflected by the concentric phase regulator 1 in controlled three zones, modulate, change into linearly polarized light through quarter-wave plate 6 again, the polarization direction of the linearly polarized light of this moment is vertical with the polarization of incident light direction, so be polarized spectroscope 5 reflections.Using method is identical with embodiment 1, when present embodiment is linearly polarized light beam at incident beam, can improve the utilization factor of luminous energy.
The structure of present embodiment as shown in Figure 5, in the present embodiment, the oblique controlled three zones modulation face of phase regulator 1 with one heart that is mapped to of incident light, three phase regions of the concentric phase regulator 1 in controlled three zones this moment are concentration ellipse, the method parallel line surface of long axis direction and incident beam, the projection of concentration ellipse on the normal beam direction of propagation still are the donut structure.Present embodiment is compared with specific embodiment 2 with specific embodiment 1, and slightly high to the requirement of the concentric phase regulator 1 in controlled three zones, result of use is identical.
Adjustable smooth tweezers device of the present invention, simple in structure, easy to operate, realize robotization easily; Can implement the handling process of particle continuously; Control the transport distance and the carrying direction of particle easily.
Claims (5)
1, a kind of device of adjustable smooth tweezers, it is characterized in that being equipped with on the working direction of incident parallel beam controlled three zones phase regulator (1) and object lens (2) with one heart, this concentric phase regulator (1) in controlled three zones is from inside to outside by central circular phase region (102), interior annular phase region (103) and outer ring phase region (101) constitute, and the phase adjusted face is vertical with optical axis, these the controlled three zones internal diameter and external diameter of the interior annular phase region (103) of phase regulator (1) are with one heart calculated definite according to the distance of material grains needs carrying by diffraction theory, central circular phase region (102) is identical with the phase place of outer ring phase region (101), and these controlled three zones phase regulator (1) with one heart link to each other with phase adjusted controller (4).
2, the device of adjustable smooth tweezers according to claim 1 is characterized in that the concentric phase regulator (1) in described controlled three zones is the transmission-type regulator, or reflective regulator.
3, the device of adjustable smooth tweezers according to claim 1, it is characterized in that described controlled three zones with one heart are equipped with spectroscope (5) on the light incident direction of phase regulators (1), the controlled three zones modulated beam of light of phase regulator (1) reflection are with one heart reflected by spectroscope (5), and object lens (2) place on the emitting light path of spectroscope (5) modulated beam of light.
4, the device of adjustable smooth tweezers according to claim 1, it is characterized in that between concentric phase regulator (1) in controlled three zones and spectroscope (5), being equipped with quarter-wave plate (6), this quarter-wave plate (6) is vertical with optical axis, and long axis direction and incident light polarization direction are at 45, spectroscope (5) adopts polarization spectroscope, to the incident beam transmission, to seeing through the light modulated reflection of quarter-wave plate (6).
5, the device of adjustable smooth tweezers according to claim 1, it is characterized in that being mapped to controlled three zones with one heart during the modulation face of phase regulators (1) when incident light is oblique, controlled three zones three phase regions of phase regulator (1) with one heart are concentration ellipse, the method parallel line surface of long axis direction and incident beam.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410053443 CN1285947C (en) | 2004-08-04 | 2004-08-04 | Device for regulating light tweezers |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410053443 CN1285947C (en) | 2004-08-04 | 2004-08-04 | Device for regulating light tweezers |
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| CN1588177A true CN1588177A (en) | 2005-03-02 |
| CN1285947C CN1285947C (en) | 2006-11-22 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100570438C (en) * | 2008-07-30 | 2009-12-16 | 中国科学院上海光学精密机械研究所 | Multifunctional inverse direction optical tweezers |
| CN101241239B (en) * | 2007-02-08 | 2011-04-13 | 瑞鼎科技股份有限公司 | Optical tweezer generation device capable of providing momentum and method for allowing for momentum of optical tweezer |
| CN101383197B (en) * | 2007-09-05 | 2012-04-11 | 瑞鼎科技股份有限公司 | Apparatus and method for converting optical clamp |
| CN102736274A (en) * | 2012-07-10 | 2012-10-17 | 大连理工大学 | Tunable metamaterial optical tweezer based on liquid crystal material |
| CN103592782A (en) * | 2013-10-24 | 2014-02-19 | 复旦大学 | Nanometer biological optical tweezers based on optical micro-flow annular resonant cavity |
| CN112802620A (en) * | 2021-01-18 | 2021-05-14 | 郑州轻工业大学 | Method and apparatus for manipulating microparticles |
-
2004
- 2004-08-04 CN CN 200410053443 patent/CN1285947C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101241239B (en) * | 2007-02-08 | 2011-04-13 | 瑞鼎科技股份有限公司 | Optical tweezer generation device capable of providing momentum and method for allowing for momentum of optical tweezer |
| CN101383197B (en) * | 2007-09-05 | 2012-04-11 | 瑞鼎科技股份有限公司 | Apparatus and method for converting optical clamp |
| CN100570438C (en) * | 2008-07-30 | 2009-12-16 | 中国科学院上海光学精密机械研究所 | Multifunctional inverse direction optical tweezers |
| CN102736274A (en) * | 2012-07-10 | 2012-10-17 | 大连理工大学 | Tunable metamaterial optical tweezer based on liquid crystal material |
| CN102736274B (en) * | 2012-07-10 | 2014-06-11 | 大连理工大学 | Tunable metamaterial optical tweezer based on liquid crystal material |
| CN103592782A (en) * | 2013-10-24 | 2014-02-19 | 复旦大学 | Nanometer biological optical tweezers based on optical micro-flow annular resonant cavity |
| CN103592782B (en) * | 2013-10-24 | 2016-05-11 | 复旦大学 | Nano biological light tweezer based on light miniflow ring resonator |
| CN112802620A (en) * | 2021-01-18 | 2021-05-14 | 郑州轻工业大学 | Method and apparatus for manipulating microparticles |
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| CN1285947C (en) | 2006-11-22 |
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