CN1579490A - Traditional Chinese medicinal preparation for women's menalgia - Google Patents
Traditional Chinese medicinal preparation for women's menalgia Download PDFInfo
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- CN1579490A CN1579490A CN 200410018563 CN200410018563A CN1579490A CN 1579490 A CN1579490 A CN 1579490A CN 200410018563 CN200410018563 CN 200410018563 CN 200410018563 A CN200410018563 A CN 200410018563A CN 1579490 A CN1579490 A CN 1579490A
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Abstract
The invention belongs to medicine technology field, which concretely is a Chinese traditional medicine for curing women dysmenorrheal. The medicine includes nutagrass flatsedge rhizome, glycerin, isinglass and antiseptic and accessories. Its character lies in: the proportion of the prescription is: the nutagrass flatsedge rhizome volatile oil is 30-150mg, the isinglass is 10 shares, and the glycerin is 3-4 shares and proper amount of antiseptic agent. Compared with current technology, it extracts the acting part of the effective ingredients in the Chinese traditional medicine, upgrades the curative effect, and uses popular soft capsule preparation; the sufferer is easy to accept. The soft capsule has a quick action, high biology utilization rate compared with other solid preparations.
Description
[technical field]
The invention belongs to medical technical field, specifically a kind of Chinese medicine preparation for the treatment of dysmenorrhes.
[technical background]
Dysmenorrhea (Dys menorrhea) is meant between moon paramenstrum, lower abdomen and waist spasmic pain, when serious with feel sick, vomiting, cold extremities, especially be more common in unmarried young women, dysmenorrhea can be divided into 2 big classes, a kind of is the obvious pathological changes of non-reproductive system, is called primary dysmenorrhea (Primary Dys menorrhea), generally begins and will take place in menophania.Another kind is the dysmenorrhea that is caused by clear and definite disease, secondary dysmenorrhea (Secondary Dys menorrhea), itself and primary dysmenorrhea have obvious difference, can cause that the time that dysmenorrhea occurs is just to begin after menorrhea a period of time (mostly being 3 years) to take place by genital organ diseases such as edeitis, hysteromyoma, endometriosis.Epidemiological study shows that primary dysmenorrhea is the common disease of present gynecological, uses different investigation methods, and its rate is between 20%～90%, for influencing the common cause of women's operate as normal and quality of life.
Dysmenorrhea is owing to its high incidence causes people's attention, in several investigation, find at young women, woman worker's absence rate that dysmenorrhea causes is between 34%～50%, about 10% primary dysmenorrhea patient can seriously have to work in 1～3 day to every month, the absence rate that causes in this situation of the U.S. and when thinking that corresponding economic loss has 600,000,000 work about every year and 2,000,000,000 dollars.In addition, be in a bad way but still adhere in the middle of the patient of work that cause productivity ratio to descend easily, possibility of accident occurrence rises, degradation under the work quality at those.The appearance of NSAID (non-steroidal anti-inflammatory drug) and oral contraceptive makes this sick sickness rate greatly reduce.In recent years, pathogenesis and the treatment to primary dysmenorrhea both at home and abroad had further research, and obtained many achievements.Motherland's medical science also has extraordinary effect for dysmenorrhea treatment, and efficacy consolidation, toxic and side effects are little, and unique advantage is arranged.But it is still less and not deep for the research of this respect both at home and abroad.For the research of the mechanism of Chinese medicine dysmenorrhea, and, become a big problem of Chinese medicine research worker how to its exploitation and apply to clinically.
Chinese medicine is to TREATMENT OF DYSMENORRHOEA, and curative effect is by clinical confirmation.The traditional Chinese medical science thinks that primary dysmenorrhea mainly is because the women between menstrual period, is subjected to the influence of paathogenic factor, cause dashing and appoint strongly fragrant resistance or cold accumulating in meridian, make QI-blood circulation not smooth, the circulation of uterus menses is obstructed, consequently " stagnation of QI and blood may bring about pain " or dash to appoint, uterus lose in moistening foster, Rong Ze pain.Time, character according to pain, and menstruation characteristics, patient's body constitution etc. is carried out determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs when passing through, dysmenorrhea can be divided into pattern of syndrome such as qi depression to blood stasis, cold and stagnate, dampness and heat stasis, deficient qi and blood, deficiency of both the liver and kidney, utilization classic prescriptions such as SHAOFU ZHUYN DECOCTION, SIWU TANG, decoction for warming channels, accent liver soup etc. are added to simplify to carry treats, and can obtain better therapeutic effect.
Rhizoma Cyperi is the dry rhizome of sedge dried tuber Cyperusrotunduslinn, is conventional Chinese medicine, has the effect that bleed resolving depression, regulating menstruation alleviate pain.The Rhizoma Cyperi fluid extract can suppress the contraction of Cavia porcellus, rabbit, cat, dog plasmon palace (pregnant and unpregnancy), studies its effective ingredient at present and is mainly α-cyperone.Experiment showed, that the spontaneity that can suppress unpregnancy isolated rat uterus muscle effectively shrinks, suppress the contraction of the isolated uterine flesh that oxytocin causes simultaneously, and be dose-dependence, is the main effective ingredient that the Rhizoma Cyperi regulating menstruation is alleviated pain.
[summary of the invention]
The objective of the invention is basis the Chinese medicine preparation and the preparation technology thereof that dose is big, uncertain therapeutic efficacy is cut, the uppity shortcoming of quality provides a kind of and fills a prescription rationally, curative effect is fast, side effect is little of similar preparation in the past.
A kind of Chinese medicine preparation for the treatment of dysmenorrhes is provided for achieving the above object, comprise adjuvants compositions such as Chinese medicine Rhizoma Cyperi and gelatin, glycerol, antiseptic, it is characterized in that: the proportioning of prescription is Rhizoma Cyperi volatile oil 30-150mg, 10 parts in gelatin, glycerol 3-4 part and an amount of antiseptic; Dosage form can be soft capsule, drop pill and transdermal absorption formulation; Chinese medicine preparation soft capsule product comprises softgel shell and content composition, wherein contains 10 parts in gelatin, glycerol 3-4 part and an amount of antiseptic in every softgel shell, and the content in every capsules is every and contains Rhizoma Cyperi volatile oil 30-150mg and an amount of solvent and stabilizing agent; Purposes also can be used for making an addition on the carriers such as sanitary towel, cotton wool as adjuvant to be used.
Preparation technology of the present invention may further comprise the steps: get it filled (1): in Rhizoma Cyperi 1-5 part ratio; (2) pulverize; (3) extract: extract the volatile oil component through the method for supercritical fluid extraction or the method for vapor distillation; (4) mix: add proper amount of edible vegetable oil, glycerol and suitable quantity of water mix homogeneously; (5) pelleting: degassing back compacting; (6) drying; (7) get finished product.
The present invention compares with prior art, extracts the useful effect position of Chinese medicine, has improved therapeutic effect, and adopt popular soft capsule preparation, make the patient be easy to accept, and, soft capsule is other oral solid formulations relatively, have characteristics rapid-action, that bioavailability is high and advantage.
[description of drawings]
Fig. 1 is a process chart of the present invention.
Referring to accompanying drawing, 1 for getting it filled, and 2 for pulverizing, and 3 for extracting, and 4 for mixing, and 5 be pelleting, and 6 is drying, 7 be finished product.
[specific embodiment]
The invention will be further described below in conjunction with accompanying drawing.
Getting the Chinese medicine Rhizoma Cyperi earlier pulverizes, extract total volatile oil through the method for supercritical fluid extraction or the method for vapor distillation, it is miscible to add edible vegetable oil then, then add an amount of glycerol and suitable quantity of water mix homogeneously, through being pressed into ball after the degassing, carry out dried at last, get product, every contains Rhizoma Cyperi volatile oil 30-150mg.
Claims (5)
1. a Chinese medicine preparation for the treatment of dysmenorrhes comprises adjuvants compositions such as Chinese medicine Rhizoma Cyperi and gelatin, glycerol, antiseptic, it is characterized in that: the proportioning of prescription is Rhizoma Cyperi volatile oil 30-150mg, 10 parts in gelatin, glycerol 3-4 part and an amount of antiseptic.
2. as claims 1 described a kind of Chinese medicine preparation for the treatment of dysmenorrhes, it is characterized in that: dosage form can be soft capsule, drop pill and transdermal absorption formulation.
3. as claims 1 or 2 described a kind of Chinese medicine preparation for the treatment of dysmenorrhes, it is characterized in that: Chinese medicine preparation soft capsule product comprises softgel shell and content composition, wherein contain 10 parts in gelatin, glycerol 3-4 part and an amount of antiseptic in every softgel shell, the content in every capsules is Rhizoma Cyperi volatile oil 30-150mg and an amount of solvent and stabilizing agent.
4. as claims 1 described a kind of Chinese medicine preparation for the treatment of dysmenorrhes, it is characterized in that: purposes also can be used for making an addition on the carriers such as sanitary towel, cotton wool as adjuvant to be used.
5. as claims 1 described a kind of Chinese medicine preparation for the treatment of dysmenorrhes, it is characterized in that: preparation technology may further comprise the steps: get it filled (1): in Rhizoma Cyperi 1-5 part ratio; (2) pulverize; (3) extract: extract the volatile oil component through the method for supercritical fluid extraction or the method for vapor distillation; (4) mix: add proper amount of edible vegetable oil, glycerol and suitable quantity of water mix homogeneously; (5) pelleting: degassing back compacting; (6) drying; (7) get finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410018563 CN1579490A (en) | 2004-05-21 | 2004-05-21 | Traditional Chinese medicinal preparation for women's menalgia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410018563 CN1579490A (en) | 2004-05-21 | 2004-05-21 | Traditional Chinese medicinal preparation for women's menalgia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1579490A true CN1579490A (en) | 2005-02-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410018563 Pending CN1579490A (en) | 2004-05-21 | 2004-05-21 | Traditional Chinese medicinal preparation for women's menalgia |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101927031A (en) * | 2010-09-03 | 2010-12-29 | 云南清逸堂实业有限公司 | Sanitary towel heat sensitizer |
-
2004
- 2004-05-21 CN CN 200410018563 patent/CN1579490A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101927031A (en) * | 2010-09-03 | 2010-12-29 | 云南清逸堂实业有限公司 | Sanitary towel heat sensitizer |
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