CN1559508A - Medicine for preventing and curing laryngolaryngitis and its preparation method - Google Patents
Medicine for preventing and curing laryngolaryngitis and its preparation method Download PDFInfo
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Abstract
A Chinese medicine for treating laryngolaryngitis and upper respiratory tract inflammation is prepared from 10 Chinese-medicinal materials including scrophularia root, ophiopogon root, ciccada slough, myrobalan seed, etc through proportionally mixing, extracting and mixing with sugar or syrup and additive.
Description
Technical field
The present invention relates to a kind of pure Chinese medicine medicine and preparation method for the treatment of pharyngolaryngitis, specifically
A kind of medicine and preparation method with control laryngopharyngeal diseases of health care and therapeutical effect.
Background technology
Pharyngolaryngitis is a kind of common multiple upper respiratory tract infection disease, have a strong impact on people's orthobiosis and social communication, can also bring out other pathological changes as untimely treatment, as acute rhinitis, acute sinusitis, acute tonsillitis, pulmonary infection etc., untimely thoroughly and repeatedly outbreak of acute pharyngitis treatment then transfers chronic pharyngitis to, cervical region radiotherapy or other physical property, chemical irritation, various chronic diseases such as anemia, constipation, the lower respiratory tract chronic inflammatory disease, but cardiovascular disease etc. are the secondary chronic pharyngitis also, the chronic pharyngitis course of disease is many more than 3 months, patient Chang Yin suffers from cold, flu, reasons such as fatigue make sx, thus pharyngitis be pharyngeal commonly encountered diseases be again the chronic disease that refractory is healed.The traditional Chinese medical science thinks that throat is that yin channel is compiled part, the door of lung stomach discrepancy, therefore, and the heresy of wind heat, invasion and attack lung stomach injures cloudy Tianjin or health hyperactivity of fire caused by deficiency of YIN or outside stimulus, all can cause laryngopharynx swelling and pain, aphonia, malaise symptoms such as hoarse.That is to say that laryngopharyngitis is to be caused by following factor: the one, cause by diseases caused by exogenous pathogenic factor virus, pathogenic bacteria; The 2nd, from health void, what imbalance of YIN and YANG brought out; The 3rd and since air pollution, dust, harmful gas, radiotherapy stimulate pharyngeal due to, Chinese medical discrimination thinks that the pharyngitis patient mostly is the deficiency of YIN, the deficiency of vital energy or expectorant heat, the body constitution of hold concurrently wind, heat, expectorant type, so normal heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, method of removing heat from the lung and dissipating phlegm of adopting in treatment.Western medicine class throat buccal tablet mostly is antibiotic, sulfonamides antibiotic medicine, mainly contains ground Kui chloramines, the pyridine of hydrochloric acid chloroethene, cydiodine etc., has the germ-resistant effect of partly sterilised, act on single, a little less than pharyngolaryngitis and whole body therapeutic effect.And confection class lozenge in the market, its main component mostly is Fructus Canarii, Fructus Momordicae and a large amount of Oleum menthae, Eucalyptus oils, and is refrigerant based on the part, and what effect the treatment of pharyngolaryngitis is not had.Publication number is CN1456344A, open day be that the application for a patent for invention on November 19th, 2003 discloses a kind of pharmaceutical composition for the treatment of pharyngolaryngitis and preparation method thereof, it can alleviate laryngopharynx swelling and pain, dried symptom such as make an uproar rapidly, but its antibacterial and anti-inflammation functions is not satisfactory.
Summary of the invention
Technical problem to be solved by this invention provides a kind of pure Chinese medicinal preparation of preventing and treating throat disease, and this medicine has clearing throat, preventing phlegm from forming and stopping coughing, antipyretic and antidote functions.The present invention also provides manufacturing method for above mentioned medicine.
Medicine of the present invention is made (by weight ratio) by following component:
Radix Scrophulariae 1-50 1-34 Radix Ophiopogonis Periostracum Cicadae 1-20 Fructus Chebulae 1-34 Radix Platycodonis 1-34
Radix Isatidis 1-34 Semen Sterculiae Lychnophorae 1-2 Radix Rehmanniae 1-50 Radix Glycyrrhizae 1-20 FRUCTUS TERMINALIAE IMMATURUS 1-10
Preferred weight proportioning of the present invention (by weight ratio)
Radix Scrophulariae 1-25 1-17 Radix Ophiopogonis Periostracum Cicadae 1-10 Fructus Chebulae 1-17 Radix Platycodonis 1-17
Radix Isatidis 1-17 Semen Sterculiae Lychnophorae 1-2 Radix Rehmanniae 1-25 Radix Glycyrrhizae 1-10 FRUCTUS TERMINALIAE IMMATURUS 1-6
Medicine of the present invention can add pharmaceutic adjuvant as required, pharmaceutic adjuvant can be diluent, binding agent, correctives, excipient, as starch, sucrose, sorbitol, mannitol, xylitol, sodium carboxymethyl cellulose, potassium sorbate, Oleum menthae, orange essence oil, fruity flavor, chocolate essence, citric acid.
The present invention can make any clinical pharmaceutical preparation that is applicable to according to existing process of Chinese medicine preparation, comprises solid preparation (granule, tablet), liquid preparation (syrup, mixture), spray etc.The route of administration absorption of can adopting the oral cavity buccal, swallow or spray.When aforementioned pharmaceutical compositions was prepared into medicament, according to the special requirement of preparation, the pharmaceutic adjuvant that can add other again was as excipient.The preferred dosage form of the present invention is tablet, syrup and oral spray.
Pharmacological action of the present invention shows as: 1, can expand blood capillary, microcirculation improvement, increase the secretion of saliva and sialoprotein; 2, can reduce inflammation pain causedly, acutely inflamed oozing out with edema had the obvious suppression effect; 3, bacteriostasis has the obvious suppression effect to alpha streptococcus, beta hemolytic streptococcus, staphylococcus aureus, Diplococcus pneumoniae, meningococcus, escherichia coli etc.Simultaneously, by the clear asthenic fire of its YIN nourishing and the production of body fluid promoting effect, eliminating the pathogens from the lung heat makes the body equilibrium between yin and yang, reaches clearing throat, YIN nourishing and the production of body fluid promoting, the effect that detoxifcation pathogenic fire purging specimen is controlled altogether.Particularly some epidemic diseases epidemic disease there is certain preventive and therapeutic effect, thereby as the specific drug of resisting SARS.
The preparation method of medicine of the present invention is:
1, the medicine adding medical material total amount 4-12 decocting doubly with above-mentioned prescription boils 1-4 time, extracts aqueous soluble active constituent, collects filtrate respectively, and standing sedimentation 12-48 hour, get supernatant;
2, above-mentioned supernatant merging being concentrated into relative density is 1.28～1.34 (about 20 ℃), obtains clear paste;
3, add diluent, binding agent, correctives, excipient pharmaceutic adjuvant, mix homogeneously again;
4, the medicine behind the mix homogeneously is made buccal tablet, syrup or oral spray.
Relative density technological parameter in the preparation method of the present invention must strictly be controlled, and in span of control of the present invention, can give full play to the multiple effect of pharmaceutic adjuvant.
The present invention has pharynx-clearing throat-benefiting, YIN nourishing and the production of body fluid promoting, and the effect of detoxifcation pathogenic fire purging is used for laryngopharynx swelling and pain, aphonia and upper respiratory tract infection.
An important feature of the present invention is a pure Chinese medicinal preparation, has the effect that prevention and treatment are worked along both lines.And the foodstuff larynx moistening candy mostly is the combination of Fructus Momordicae, Oleum menthae, eucalyptus oil on the market, can produce refrigerant sense to throat is local, and what effect the treatment of pharyngolaryngitis is not had.Though the advantage than some Western medicine is antiinflammation, but do not contain antibiotics, do not influence the growth and the balance of oral cavity normal flora, when improving throat symptom (as swell and ache, causalgia, foreign body sensation, titillation, dry cough, hoarseness, aphonia etc.), can regulate the allomeric function that improves the patient, strengthen the immunocompetence of self, and without any side effects.Radix Scrophulariae, Radix Ophiopogonis, Radix Glycyrrhizae, Radix Platycodonis in the side, both can relieve inflammation or internal heat detoxifcation and throat, but again YIN nourishing and the production of body fluid promoting with clear asthenic fire, but eliminating phlegm and relieving cough also; The Radix Rehmanniae, but clearing away heat and cooling blood yin nourishing, the excessive thirst that is used for interior-heat caused by deficiency of YIN is evident in efficacy, but the source of heat clearing away disease; Radix Isatidis, clearing away lung-heat is separated pyretic toxicity, the removing heat from blood sore-throat relieving, the disease of be used for sore throat, swallowing poison, carbuncle not only has inhibitory action to influenza virus, and multiple virus and various pathogens infection are also had inhibitory action and antiinflammatory action; Periostracum Cicadae, loose wind heat extraction, spasmolytic, sore-throat relieving are arrogated to oneself and are controlled pharyngalgia, hoarseness; FRUCTUS TERMINALIAE IMMATURUS, Semen Sterculiae Lychnophorae, clearing away lung-heat is treated the pharyngodynia with dryness that wind heat is stopped up Sheng, hoarseness and aphonia, dry cough without phlegm; Fructus Chebulae's gas of astringing the lung is treated the deficiency of the lung with Radix Glycyrrhizae, Radix Platycodonis compatibility and is breathed with cough, and chronic cough is more than, chronic cough aphonia, and the oral mucosa wound surface had astriction; All medicines share, and have relieving sore-throat by clearing away heat, YIN nourishing and the production of body fluid promoting, and YIN nourishing is quenched the thirst, detoxifcation pathogenic fire purging, the effect of eliminating phlegm and relieving cough.Can take stopgap measures and can effect a permanent cure, can be used for acute and chronic pharyngolaryngitis patient and, dry pharynx, itching throat, pharyngalgia or other throat discomfort person due to environmental pollution, dust, harmful gas stimulate Yin excessive with throat, can be widely used in men and women, old and young, weak patients does not have any toxicity, and safety is better.
Another important feature of the present invention is that medicine directly acts at bottleneck throat, alleviates malaise symptoms such as dry pharynx, itching of the throat, pharyngalgia rapidly.Because containing slowly, it is pharyngeal that medicine can be rested on the long period, and keep the drug level on the oral mucosa, reaches therapeutic purposes.
The present invention has following effect: the energy clearing throat, repair the throat damaged cell rapidly, and recover normal function; The energy lung-heat clearing and detoxification, heat-clearing and toxic substances removing, nourishing lung yin is discharged rubbish in the body; The energy YIN nourishing and the production of body fluid promoting, the secretion replenishing and throat moistening lung moistening, pain reaction diminishes inflammation; The energy relieving cough and expelling phlegm, the dilution sputum is calmed down stimulation, fast eliminating phlegm and stopping cough; The energy refreshment, refrigerant larynx refreshing, inlet take effect allaying tiredness.
The present invention under unified clinical indexes, has finished 316 routine clinical observation on the therapeutic effect by Wuhan City four hospitals, Wuhan City institute of traditional Chinese medicine, the fellowship clinical verification of Wuhan City one hospital altogether, and observed result is as follows:
Produce effects enabledisable total effective rate
Hospital's case sum
Example number % example number % example number % example number %
City four hospitals 120 23 19.17 95 79.16 2 1.67 118 98.33
City institute of traditional Chinese medicine 140 22 15.7 118 84.3--140 100.0
City one hospital 56 2 3.6 43 76.8 11 19.6 45 80.36
Add up to 316 47 14.92 56 81 13 4.1 303 95.89
Curative effect judging standard is:
1, produce effects: in course of treatment the throat cardinal symptom disappear (swell and ache, odynophagia, causalgia, be slightly cold, low grade fever, stalk sense or foreign body, very itch, dry cough, thirsty, hoarseness or hoarse etc.).Topical manifestations: the pharyngeal mucosa redness disappears, and it is good that function of pronunciation is recovered.
2, effective: the bottleneck throat cardinal symptom alleviates in two courses of treatment.
3, invalid: subjective symptoms, local circumstance all do not have the improver in two courses of treatment.
Visible the present invention treats pharyngolaryngitis 316 examples by table, and produce effects reaches and effectively is respectively 14.9% (47/316) and 81% (256/316), and clinical total effective rate is 95.9%.
In order further to verify lozenge (lysozyme sheet) curative effect and the changes of biochemical indexes that this product and Western medicine are commonly used, with identical route of administration, identical buccal tablet dosage form, this product (being the pharynx-clearing throat-benefiting sheet) and lysozyme sheet have been carried out controlled observation, selection of clinical 60 routine disease times are 2-5 days pharyngolaryngitis patient, be divided into two groups at random, every group 30 example, it with the present invention respectively the treatment group, the lysozyme sheet is that matched group carries out clinical treatment, curative effect that parallel observations is two groups and changes of biochemical indexes, and two groups all with the check in back three days of taking medicine, judge clinical efficacy to unify index, the result is as follows:
One, clinical observation on the therapeutic effect result
| Group | Case produce effects enabledisable total effective rate n example number % example number % example number % example number % |
| Treatment group matched group | ??30??????13?43.33???16?53.33??13.33????29?96.7 ??30??????12?40.0????15?50.0???310.0????27?90.0 |
Two groups of clinical effectiveness are learned by statistics and are handled, and P＞two groups of therapeutic effect no significant differences of 0.05 explanation shows that the pharynx-clearing throat-benefiting sheet has consistent curative effect with lysozyme sheet treatment pharyngolaryngitis.
Two, changes of biochemical indexes (total white blood cells and classification) situation
The classification of total white blood cells neutrophilic granulocyte
Case
Group
It is normal to become a full member after the preceding super normal therapeutic of informal dress medicine of becoming a full member after the super normal therapeutic before taking medicine
n???????n?％??????????n?％??????????????????n?％????????n?％
Treatment organizes 30 19 63.33 18 60.00 15 50.00 12 40.00
Matched group 30 12 40.00 9 30.00 14 46.67 9 30.00
The treatment of observation pharynx-clearing throat-benefiting sheet is organized 30 examples and is taken medicine the proleukocyte sum above normal value (10000-15000/mm
3) be 19 examples, treatment back 18 examples are often become a full member, and it is 15 examples that the neutrophilic granulocyte classification surpasses normal person (76-90%), and treatment back 12 examples are become a full member often.
Observe lysozyme sheet matched group 30 examples, the preceding 12 routine total white blood cellses of taking medicine surpass normal, and treatment back 9 examples are often become a full member, and the neutrophilic granulocyte classification surpasses normal person's 14 examples, and treatment back 9 examples transfer to normally.
This shows, traditional Chinese medicine mouth buccal tablet pharynx-clearing throat-benefiting sheet and Western medicine buccal tablet lysozyme sheet, to the therapeutic effect of 60 routine pharyngolaryngitis and the situation of blood phase change, the result is basic identical, all can reach excellent curative, continue to observe two groups late result with, find that the late result after the drug withdrawal of the present invention is better than matched group.Liquid preparation of the present invention curative effect with buccal tablet in clinical trial is consistent, and mouthfeel is better, and is easy for patients to accept, has application value.The clinical efficacy result of study is as follows:
1, medicine of the present invention has YIN nourishing and the production of body fluid promoting, clearing away lung-heat and moistening for dryness, detoxifcation, the function of throat.Be used for the treatment of that acute and chronic pharyngolaryngitis has certain curative effect and can play tonsillitis and improve the local symptom effect, total effective rate reaches 95.9%.
2, one of dosage form of the present invention is a buccal tablet, and route of administration all belongs to buccal, can make the medicine long duration of action in bottleneck throat, effectively improve dry pharynx, pharyngalgia, foreign body sensation, very itch and disease such as hoarseness, this product has antipruritic antitussive, eliminates the phlegm to alleviate pain, promote the production of body fluid and quench one's thirst, clinical effectiveness such as the bright throat of sound producing.
3, other dosage form of the present invention such as syrup, mixture, oral spray etc. have identical clinical efficacy.
The specific embodiment
The invention will be further described below in conjunction with embodiment, and the component in the embodiment of the invention is a components by weight percent.
Embodiment 1:
Radix Scrophulariae 3 Periostracum Cicadaes, 2 Fructus Chebulaes, 5 Radix Ophiopogonis 3 Radix Platycodoniss 3
Radix Isatidis 3 Semen Sterculiae Lychnophoraes 2 Radix Rehmanniae 5 Radix Glycyrrhizaes 1 FRUCTUS TERMINALIAE IMMATURUS 1
Production method is as follows: with the composition of medicine of above-mentioned prescription, the decocting that adds 6 times of medical material total amounts boils 4 times, collects filtrate respectively, and with filtrate standing sedimentation 24 hours, gets supernatant; It is 1.33 (20 ℃) that above-mentioned supernatant merging is concentrated into relative density, again with Icing Sugar, starch, the abundant mix homogeneously of sodium carboxymethyl cellulose, granulate, and batching, tabletting, promptly.
Embodiment 2:
Radix Scrophulariae 20 Periostracum Cicadaes, 10 Fructus Chebulaes, 40 Radix Ophiopogonis 20 Radix Platycodoniss 20
Radix Isatidis 20 Semen Sterculiae Lychnophoraes 2 Radix Rehmanniae 40 Radix Glycyrrhizaes 2 FRUCTUS TERMINALIAE IMMATURUS 6
Production method is as follows: with the composition of medicine of above-mentioned prescription, the decocting that adds 12 times of medical material total amounts boils 2 times, collects filtrate respectively, and with filtrate standing sedimentation 12 hours, gets supernatant; It is 1.34 (20 ℃) that above-mentioned supernatant merging is concentrated into relative density, again with Icing Sugar, sorbitol, the abundant mix homogeneously of starch, granulate, and with the Oleum menthae batching, tabletting, promptly.
Embodiment 3:
Radix Scrophulariae 7 Periostracum Cicadaes, 4 Fructus Chebulaes, 10 Radix Ophiopogonis 3 Radix Platycodoniss 5
Radix Isatidis 5 Semen Sterculiae Lychnophoraes 1 Radix Rehmanniae 5 Radix Glycyrrhizaes 2 FRUCTUS TERMINALIAE IMMATURUS 3
Production method is as follows: with the composition of medicine of above-mentioned prescription, the decocting that adds 10 times of medical material total amounts boils 2 times, collects filtrate respectively, and with filtrate standing sedimentation 20 hours, gets supernatant; It is 1.32 (20 ℃) that above-mentioned supernatant merging is concentrated into relative density, again with Icing Sugar, the abundant mix homogeneously of xylitol, granulates, and drying adds the fruity flavor batching, gets granule.
Embodiment 4:
Radix Scrophulariae 20 Periostracum Cicadaes, 10 Fructus Chebulaes, 40 Radix Ophiopogonis 20 Radix Platycodoniss 20
Radix Isatidis 20 Semen Sterculiae Lychnophoraes 2 Radix Rehmanniae 40 Radix Glycyrrhizaes 2 FRUCTUS TERMINALIAE IMMATURUS 10
Production method is as follows: with the composition of medicine of above-mentioned prescription, the decocting that adds 8 times of medical material total amounts boils 4 times, collects filtrate respectively, and with filtrate standing sedimentation 24 hours, gets supernatant; It is 1.34 (20 ℃) that above-mentioned supernatant merging is concentrated into relative density, again with Icing Sugar, mannitol, the abundant mix homogeneously of citric acid, granulates, and drying with Oleum menthae, orange essence oil batching, gets granule.
Embodiment 5:
Radix Scrophulariae 7 Periostracum Cicadaes, 3 Fructus Chebulaes, 10 Radix Ophiopogonis 4 Radix Platycodoniss 5
Radix Isatidis 5 Semen Sterculiae Lychnophoraes 2 Radix Rehmanniae 10 Radix Glycyrrhizaes 2 FRUCTUS TERMINALIAE IMMATURUS 2
Production method is as follows: with the composition of medicine of above-mentioned prescription, the decocting that adds 6 times of medical material total amounts boils 3 times, collects filtrate respectively, and with filtrate standing sedimentation 32 hours, gets supernatant; It is 1.30 (20 ℃) that above-mentioned supernatant merging is concentrated into relative density, again with syrup, sorbitol, potassium sorbate, the abundant mix homogeneously of chocolate essence, gets syrup.
Embodiment 6:
Radix Scrophulariae 6 Periostracum Cicadaes, 3 Fructus Chebulaes, 10 Radix Ophiopogonis 5 Radix Platycodoniss 5
Radix Isatidis 6 Semen Sterculiae Lychnophoraes 1 Radix Rehmanniae 10 Radix Glycyrrhizaes 2 FRUCTUS TERMINALIAE IMMATURUS 1
Production method is as follows: with the composition of medicine of above-mentioned prescription, the decocting that adds 5 times of medical material total amounts boils 4 times, collects filtrate respectively, and with filtrate standing sedimentation 48 hours, gets supernatant; It is 1.28 (20 ℃) that above-mentioned supernatant merging is concentrated into relative density, again with rare syrup, sorbitol, Oleum menthae, orange essence oil, the abundant mix homogeneously of citric acid, divides the bottle of packing into, and sealing gets spray.
Embodiment 7:
Radix Scrophulariae 3 Periostracum Cicadaes, 4 Fructus Chebulaes, 5 Radix Ophiopogonis 3 Radix Platycodoniss 3
Radix Isatidis 3 Semen Sterculiae Lychnophoraes 1 Radix Rehmanniae 5 Radix Glycyrrhizaes 2 FRUCTUS TERMINALIAE IMMATURUS 1
Production method is with embodiment 6.
Embodiment 8:
Radix Scrophulariae 34 Periostracum Cicadaes, 20 Fructus Chebulaes, 50 Radix Ophiopogonis 34 Radix Platycodoniss 4
Radix Isatidis 4 Semen Sterculiae Lychnophoraes 2 Radix Rehmanniae 50 Radix Glycyrrhizaes 1 FRUCTUS TERMINALIAE IMMATURUS 8
Production method is with embodiment 2.
Claims (5)
1, a kind of medicine of preventing and treating laryngopharyngitis, it is made up of following material component (composition by weight):
Radix Scrophulariae 1-50 1-34 Radix Ophiopogonis Periostracum Cicadae 1-20 Fructus Chebulae 1-34
Radix Platycodonis 1-34 Radix Isatidis 1-34 Semen Sterculiae Lychnophorae 1-2 Radix Rehmanniae 1-50
Radix Glycyrrhizae 1-20 FRUCTUS TERMINALIAE IMMATURUS 1-10
2, a kind of medicine of preventing and treating laryngopharyngitis according to claim 1, wherein the weight ratio of each raw material is:
Radix Scrophulariae 1-25 1-17 Radix Ophiopogonis Periostracum Cicadae 1-10 Fructus Chebulae 1-17
Radix Platycodonis 1-17 Radix Isatidis 1-17 Semen Sterculiae Lychnophorae 1-2 Radix Rehmanniae 1-25
Radix Glycyrrhizae 1-10 FRUCTUS TERMINALIAE IMMATURUS 1-5
3, a kind of medicine of preventing and treating laryngopharyngitis according to claim 1 and 2 wherein can add diluent, binding agent, correctives, excipient pharmaceutic adjuvant in the said medicine component.
4, a kind of medicine of preventing and treating laryngopharyngitis according to claim 3, wherein pharmaceutic adjuvant is one or more in starch, sucrose, sorbitol, mannitol, xylitol, sodium carboxymethyl cellulose, potassium sorbate, Oleum menthae, orange essence oil, fruity flavor, chocolate essence, the Chinese holly Citron acid.
5, a kind of preparation method of preventing and treating the medicine of laryngopharyngitis, its step is as follows:
1. the medicine of the described prescription of claim 1 is added medical material total amount 4-12 decocting doubly and boil 1-4 time, the extraction aqueous soluble active constituent is collected filtrate respectively, and with filtrate standing sedimentation 12-48 hour, gets supernatant;
2. above-mentioned supernatant merging being concentrated into relative density is 1.28～1.34 (about 20 ℃), obtains clear paste;
3. add diluent, binding agent, correctives, excipient pharmaceutic adjuvant again, mix homogeneously;
4. said mixture is made solid preparation, liquid preparation, oral spray.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102885367A (en) * | 2011-07-23 | 2013-01-23 | 江西食方食坊中药食品有限公司 | Boat-fruited sterculia seed beverage with throat protecting effect and preparation method thereof |
| CN103734384A (en) * | 2013-12-20 | 2014-04-23 | 广东药学院 | Throat health beverage as well as preparation method and application thereof |
| CN103784753A (en) * | 2014-01-15 | 2014-05-14 | 纪晓青 | Chinese herbal medicine formula for treating nasopharyngitis and preparation method thereof |
| CN104095987A (en) * | 2014-07-16 | 2014-10-15 | 刘斌 | Medicine for treating swelling and pain in throat and preparation method thereof |
| CN104758573A (en) * | 2015-05-04 | 2015-07-08 | 李汶峰 | Traditional Chinese medicine for treating anaudia |
| CN104940708A (en) * | 2015-07-21 | 2015-09-30 | 厦门市医药研究所 | Chinese medicine preparation for treating pharyngitis and preparing method thereof |
| CN105079429A (en) * | 2014-05-15 | 2015-11-25 | 李东海 | Medicine for treating chronic laryngitis |
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| CN105288133A (en) * | 2015-11-10 | 2016-02-03 | 刘景城 | Traditional Chinese medicine composition clearing heat and relieving sore throat |
| CN105560812A (en) * | 2016-01-04 | 2016-05-11 | 成都富豪斯生物科技有限公司 | Decoction drug for treating acute/chronic sphagitis and preparation method thereof |
| CN106343116A (en) * | 2016-11-24 | 2017-01-25 | 西宁志培知识产权咨询有限公司 | Preparation method of throat-clearing substituting tea prepared by adopting food plants as ingredients |
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- 2004-03-09 CN CNB2004100128285A patent/CN100333770C/en not_active Expired - Lifetime
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| CN102885367B (en) * | 2011-07-23 | 2014-12-24 | 江西江中制药(集团)有限责任公司 | Boat-fruited sterculia seed beverage with throat protecting effect and preparation method thereof |
| CN102885367A (en) * | 2011-07-23 | 2013-01-23 | 江西食方食坊中药食品有限公司 | Boat-fruited sterculia seed beverage with throat protecting effect and preparation method thereof |
| CN103734384A (en) * | 2013-12-20 | 2014-04-23 | 广东药学院 | Throat health beverage as well as preparation method and application thereof |
| CN103784753A (en) * | 2014-01-15 | 2014-05-14 | 纪晓青 | Chinese herbal medicine formula for treating nasopharyngitis and preparation method thereof |
| CN105079429A (en) * | 2014-05-15 | 2015-11-25 | 李东海 | Medicine for treating chronic laryngitis |
| CN104095987A (en) * | 2014-07-16 | 2014-10-15 | 刘斌 | Medicine for treating swelling and pain in throat and preparation method thereof |
| CN104758573A (en) * | 2015-05-04 | 2015-07-08 | 李汶峰 | Traditional Chinese medicine for treating anaudia |
| CN104940708A (en) * | 2015-07-21 | 2015-09-30 | 厦门市医药研究所 | Chinese medicine preparation for treating pharyngitis and preparing method thereof |
| CN105168851A (en) * | 2015-09-10 | 2015-12-23 | 曾丽 | Detoxifying and pain-relieving preparation for treating acute pharyngitis and preparation method thereof |
| CN105288133A (en) * | 2015-11-10 | 2016-02-03 | 刘景城 | Traditional Chinese medicine composition clearing heat and relieving sore throat |
| CN105288133B (en) * | 2015-11-10 | 2019-08-09 | 刘景城 | A kind of clearing heat, relieving sore-throat Chinese medicine composition |
| CN105560812A (en) * | 2016-01-04 | 2016-05-11 | 成都富豪斯生物科技有限公司 | Decoction drug for treating acute/chronic sphagitis and preparation method thereof |
| CN106343116A (en) * | 2016-11-24 | 2017-01-25 | 西宁志培知识产权咨询有限公司 | Preparation method of throat-clearing substituting tea prepared by adopting food plants as ingredients |
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| Publication number | Publication date |
|---|---|
| CN100333770C (en) | 2007-08-29 |
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