CN1559490A - Medicine capsule for treating male infertility - Google Patents

Medicine capsule for treating male infertility Download PDF

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Publication number
CN1559490A
CN1559490A CNA2004100101102A CN200410010110A CN1559490A CN 1559490 A CN1559490 A CN 1559490A CN A2004100101102 A CNA2004100101102 A CN A2004100101102A CN 200410010110 A CN200410010110 A CN 200410010110A CN 1559490 A CN1559490 A CN 1559490A
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fructus
medicinal liquid
kidney
testis
herba
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CN1284586C (en
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王明珠
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Abstract

A Chinese medicine in the form of capsule for treating male sterility, impotence and ejaculaltion praecox is prepared from 3 Western-medicinal materials including zinc sulfate and 24 Chinese-medicinal materials including ursine seal testes and penis, saffreon, etc.

Description

A kind of medicament capsule for the treatment of male infertility
One, technical field
The present invention relates to a kind of medicine for the treatment of male infertility.
Two, background technology
At present, adopt the existing multiple formulations of China's tradition Chinese traditional treatment male infertility, generally speaking, therapeutic effect is not so satisfactory, mainly be that fertility rate is not high, curative effect is longer, and its reason is can not especially effectively improve sperm quality, survival number, mobility and solve diseases such as sexual impotence, premature ejaculation, and price costlinesses such as the Chinese medicine that has, Chinese patent medicine, Chinese medicine preparation, the patient is difficult to accept.Most Chinese herbal medicine are the traditional water decoction still, take very inconvenient.In the Western medicine of treatment infertility contain compositions such as hormone, antibiotic on the market more, human body is had certain adverse side effect, therapeutic effect is also not ideal.
Three, summary of the invention
Problem to be solved by this invention provides the medicament capsule that the Chinese medicine and western medicine of a kind of treaitng male infertility and sexual dysfunction combines, and it cures mainly because of necrospermia, few essence, semen being not liquefaction, sperm motility and energy is poor, azoospermia and sperm deformity, prostatitis, spermatitis, male infertility and sexual dysfunction diseases such as sexual impotence, premature ejaculation that obstruction of vas deferen caused specifically.This capsule is evident in efficacy, and the course of treatment is shorter, and taking convenience is cheap, can be accepted by extensive patients.
The Chinese medicine that contains by mass percentage in the medicine of the present invention has: Colla cornus cervi 2-4%, Colla Plastri Testudinis 2-3%, Testis et penis callorhini 2-4%, Placenta Hominis 2-4%, goat testis 2-4%, Gecko 2-3%, Ovum Gallus domesticus album (drying) 2-4%, Stigma Croci 2-4%, Flos Lonicerae 4-5%, Radix Salviae Miltiorrhizae 6-8%, Radix Clematidis 6-8%, Herba Epimedii 5-8%, Radix Morindae Officinalis 4-6%, Fructus Psoraleae 4-6%, Fructus Corni 4-6%, Fructus Lycii 4-8%, Semen Cuscutae 4-6%, Fructus Schisandrae Chinensis 4-6%, Fructus Rubi 4-6%, Fructus Rosae Laevigatae 4-6%, Semen Allii Tuberosi 6-8%, Rhizoma Curculiginis 5-8%, Herba Cynomorii 4-6%, Herba Cistanches 6-10%; Western medicine is: zinc sulfate 0.3-0.4%, activated calcium 3-4%, vitamin E 2.7-3%.
The pharmacology of crude drug in whole of the present invention is:
Colla cornus cervi: sweet in the mouth, salty, warm in nature, go into liver, kidney channel, main rising mended governor vessel, kidney-Yang invigorating, spermatogenesis marrow, bone and muscle strengthening effect, the treatment insufficiency of primordial QI, fear of cold is unable, insufficiency of kidney-YANG, sexual impotence, dizzy, the deficiency and coldness metrorrhagia.
Colla Plastri Testudinis: sweet in the mouth, salty, property is flat, goes into kidney, the heart, Liver Channel, mainly contains nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone effect, cures mainly the lumbocrural pain of deficiency of kidney yin, the hectic fever due to YIN-deficiency consumptive fever, muscles and bones is unstrong, and hyperactivity of YANG due to deficiency of YIN revolves on the wind syndrome caused by deficiency of consumption of body fluid caused by febrile disease.
Testis et penis callorhini: salty in the mouth, hot in nature, go into kidney channel, mainly play warming the kidney tonifying YANG, supplying vital essence and marrow effect, cure mainly the sexual impotence of kidney yang deficiency and coldness, smart cold, azoospermia.
Placenta Hominis: sweet in the mouth, salty, warm in nature, go into the heart, lung, kidney channel, mainly play QI invigorating, nourish blood, mend smart effect, cure mainly all deficient labor utmost points.
Goat testis: salty in the mouth, warm in nature, go into kidney channel, major function is supplying vital essence and marrow, cures mainly sexual impotence, premature ejaculation.
Gecko: salty in the mouth, property is flat, goes into lung, kidney channel, and major function is invigorating the lung and the kidney, received Dingchuan, cures mainly asthenia, cough.
Ovum Gallus domesticus album (drying): sweet in the mouth, property is flat, goes into the heart, spleen, stomach warp, mainly act as yin nourishing, tranquilizing mind is mended the smart marrow of giving birth to, and cures mainly deficiency of the kidney yin, after being ill convalescent period restlessness of asrhenia type and insomnia, can also replenish protein in the seminal fluid.
Stigma Croci: acrid in the mouth, warm in nature, go into the heart, Liver Channel, mainly contain promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing cures mainly obstructed, the spermatitis of deferent duct.
Flos Lonicerae: sweet in the mouth, cold in nature, go into lung, stomach, heart channel, main effect is a heat-clearing and toxic substances removing, the wind heat of loosing, and cures mainly pyretic toxicity carbuncle skin ulcer, various inflammation.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature is gone into heart channel, and major function is a blood circulation promoting and blood stasis dispelling, cures mainly obstruction of vas deferen, prostatitis.
Radix Clematidis: acrid in the mouth, warm in nature, go into urinary bladder channel, major function is removing obstruction in the collateral to relieve pain, detumescence.
Herba Epimedii: acrid in the mouth, sweet, warm in nature, go into liver, kidney channel, function is a kidney invigorating and YANG supporting, cures mainly insufficiency of kidney-YANG.
Radix Morindae Officinalis: acrid in the mouth, sweet, warm in nature, go into kidney channel, function is a kidney invigorating and YANG supporting, cure mainly suffer from a deficiency of the kidney, sexual impotence, premature ejaculation.
Fructus Psoraleae: acrid in the mouth, hardship, warm in nature, go into kidney channel, major function is a kidney invigorating and YANG supporting, spleen reinforcing antidiarrheal cures mainly impotence and seminal emission, following first deficiency and coldness.
Fructus Corni: sour in the mouth, slightly warm in nature is gone into liver, kidney channel, and function is arresting seminal emission, liver and kidney tonifying, cures mainly sexual impotence, seminal emission.
Fructus Lycii: sweet in the mouth, property is flat, goes into liver, kidney channel, and major function is nourishing extractum hepatis, replenishing vital essence to improve eyesight, cures mainly the asthenia damage of essence.
Semen Cuscutae: acrid in the mouth, sweet, property is flat, goes into liver, kidney channel, and major function is invigorating the liver and kidney, and beneficial marrow cures mainly sexual impotence.
Fructus Schisandrae Chinensis: sour in the mouth, warm in nature, go into lung, kidney channel, major function is the YIN nourishing of astringing the lung, arresting seminal emission antidiarrheal cures mainly smart sliding not solid.
Fructus Rubi: sweet in the mouth, acid, warm in nature, go into liver, kidney channel, major function is a reinforcing the kindey to control nocturnal emission, cures mainly seminal emission, premature ejaculation, sexual impotence.
Fructus Rosae Laevigatae: sour in the mouth, property is flat, goes into kidney, urinary bladder channel, and major function is the solid intestinal of arresting seminal emission, cures mainly spermatorrhea, seminal emission.
Semen Allii Tuberosi: acrid in the mouth, warm in nature, go into liver, kidney channel, major function is warming the kidney to invigorate YANG, controlling nocturnal emission with astringent drugs, cures mainly sexual impotence, seminal emission.
Rhizoma Curculiginis: acrid in the mouth, warm in nature, go into kidney channel, major function is a warming the kidney to invigorate YANG, cures mainly sexual impotence, smart cold.
Herba Cynomorii: sweet in the mouth, warm in nature, go into liver, kidney channel, major function is that benefit is smart, cures mainly sexual impotence, seminal emission.
Herba Cistanches: sweet in the mouth, acid, salty, property is flat, goes into kidney, large intestine channel, function is a kidney invigorating and YANG supporting, cure mainly suffer from a deficiency of the kidney, sexual impotence, seminal emission, few smart.
Zinc sulfate, activated calcium, vitamin E: can provide requisite trace element and nutrient substance for sperm and seminal fluid.
Prescription mechanism of the present invention is:
Chinese medicine thinks that male infertility belongs to the hepatic and renal YIN deficiency, deficiency of kidney-QI, deficiency of the kidney, the liver failing to be nourished, kidney loses warm can not going up and helps and liver, and The liver and the kidney have a common source on the traditional Chinese medical science, closely related, and male infertility mainly belongs to suffers from a deficiency of the kidney, so treat then nourishing the liver and kidney, with invigorating kidney-YANG, spermatogenesis benefit marrow.Colla cornus cervi in this medicament capsule, Colla Plastri Testudinis not only kidney-replenishing but also tonifying kidney-yin, two flavors are with going into kidney channel; Testis et penis callorhini, goat testis are with going into kidney channel, kidney invigorating and YANG supporting; Ovum Gallus domesticus album, Placenta Hominis, Gecko go into lung, kidney channel, QI invigorating, nourish blood, mend essence; Stigma Croci, Radix Salviae Miltiorrhizae compatibility blood circulation promoting and blood stasis dispelling be tissue regeneration promoting blood again, and Flos Lonicerae and Stigma Croci, Radix Salviae Miltiorrhizae match, heat-clearing and toxic substances removing, and antiinflammatory is better; Radix Clematidis, Herba Epimedii, Radix Morindae Officinalis, Fructus Psoraleae kidney invigorating and YANG supporting are with going into kidney channel; Fructus Corni, the Fructus Lycii nourishing the liver and kidney that matches, spermatogenesis, arresting seminal emission; Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Rubi, Fructus Rosae Laevigatae, Semen Allii Tuberosi match and control deficiency of kidney-QI, premature ejaculation, sexual impotence, necrospermia, few smart.More than 24 Chinese medicines can play nourishing liver and kidney, tonifying YANG, spermatogenesis controlling nocturnal emission with astringent drugs altogether after matching, nourishing YIN is YANG invigorating again, blood circulation promoting and blood stasis dispelling, heat reliving and toxin-eliminating, unobstructed deferent duct, anti-inflammation.Though zinc sulfate, activated calcium, vitamin E are Western medicine, but have no side effect, be that human body must indispensable important trace element, effective nutrition seminal fluid, more than after 24 kinds of Chinese medicines and three kinds of Western medicine match, nourishing liver and kidney, tonifying YANG, spermatogenesis benefit marrow, the foster smart function of kidney tonifying can more be strengthened, and can reach and improve sperm quality and quantity, eliminate the purpose of symptoms such as genitals's inflammation and treatment sexual impotence, premature ejaculation.
The production method of medicament capsule is: (1) will grind and be smalls earlier by the good Colla cornus cervi of quality proportioning, Colla Plastri Testudinis, Testis et penis callorhini, Placenta Hominis, goat testis, Gecko, Ovum Gallus domesticus album (drying) seven flavor Chinese medicines, be compressed into granular medicament I; (2) Stigma Croci that will be good by weight ratio, Flos Lonicerae, Radix Salviae Miltiorrhizae, Radix Clematidis, Herba Epimedii, Radix Morindae Officinalis, Fructus Psoraleae, Fructus Corni, Fructus Lycii, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Rubi, Fructus Rosae Laevigatae, Semen Allii Tuberosi, Rhizoma Curculiginis, Herba Cynomorii, Herba Cistanches totally ten seven flavor Chinese medicines add distilled water, the decocting boiling down shortens medicinal liquid I into; After taking out medicinal liquid I, add distilled water in former medicinal residues, the decocting boiling down shortens medicinal liquid II into; Take out medicinal liquid II, add distilled water again in medicinal residues, the decocting boiling down shortens medicinal liquid III into, takes out medicinal liquid III; Medicinal liquid I, II, the III of three taking-ups are mixed, decoct into concentrated solution IV; With filter pump or filter ball filtering and concentrating liquid IV; (3) add ethanol then in concentrated solution IV, leave standstill, filter, with alcohol reflux, gained suspension reconcentration to every milliliter of suspension contains crude drug 4-6 gram by distillation; (4) suspension after will concentrating is dried to ointment; Ointment, granular medicament I, by the back oven dry that is mixed of the good zinc sulfate of quality proportioning, activated calcium, vitamin E, be ground into Powdered, the capsule of packing into No. 0.
Good effect of the present invention is: the present invention adopts Chinese medicine and western medicine to organically combine, prescription science, ingenious, and compatibility is rigorous, medicine active ingredient purity height, determined curative effect, clinical treatment 108 examples are wherein cured 66 examples, produce effects 35 examples, effective 4 examples, total effective rate is 97.2%.Preparation method science, novelty, simple and easy can be given full play to the effect of medicine active ingredient, have no side effect, and price is cheap than similar drug.Be mainly used in the male is few because of sperm survival number and the mobility difference causes infertility and sexual dysfunction.Indication is: necrospermia, few essence, semen being not liquefaction, sperm motility and energy is poor, azoospermia and sperm deformity, prostatitis, spermatitis, male infertility and sexual dysfunction diseases such as sexual impotence, premature ejaculation that obstruction of vas deferen caused.
Four, the specific embodiment
Take by weighing each crude drug in whole by mass percentage and amount to 5000 grams, be respectively: Colla cornus cervi 100 grams, Colla Plastri Testudinis 100 grams, Testis et penis callorhini 100 grams, Placenta Hominis 100 grams, goat testis 100 grams, Gecko 100 grams, Ovum Gallus domesticus album (drying) 100 grams, Stigma Croci 200 grams, Flos Lonicerae 200 grams, Radix Salviae Miltiorrhizae 300 grams, Radix Clematidis 300 grams, Herba Epimedii 250 grams, Radix Morindae Officinalis 200 grams, Fructus Psoraleae 200 grams, Fructus Corni 250 grams, Fructus Lycii 250 grams, Semen Cuscutae 200 grams, Fructus Schisandrae Chinensis 200 grams, Fructus Rubi 200 grams, Fructus Rosae Laevigatae 200 grams, Semen Allii Tuberosi 300 grams, Rhizoma Curculiginis 250 grams, Herba Cynomorii 200 grams, Herba Cistanches 300 grams, zinc sulfate 15 grams, activated calcium 150 grams, vitamin e1 35 grams.
This medicament capsule manufacture method and step are: (1) restrains Geckos, 100 gram Ovum Gallus domesticus album (drying) totally 700 gram pulverizations with 100 gram Colla cornus cervis, 100 gram Colla Plastri Testudiniss, 100 gram Testis et penis callorhinis, 100 gram Placenta Hominiss, 100 Keshan Testis Caprae seu Ovis, 100, is compressed into granule I; (2) with 200 gram Stigma Crocis, 200 gram Flos Loniceraes, 300 gram Radix Salviae Miltiorrhizaes, 300 gram Radix Clematidis, 250 gram Herba Epimedii, 200 gram Radix Morindae Officinaliss, 200 gram Fructus Psoraleaes, 250 Keshan Fructus Corni, 250 gram Fructus Lycii, 200 gram Semen Cuscutae, 200 gram Fructus Schisandrae Chinensis, 200 gram Fructus Rubies, 200 gram Fructus Rosae Laevigatae, 300 gram Semen Allii Tuberosi, 250 gram Rhizoma Curculiginises, 200 gram Herba Cynomoriis, 300 gram Herba Cistanches 8000 milliliters of totally 4000 gram adding distil waters, the decocting boiling down shortens 2000 milliliters medicinal liquid I into; After taking out medicinal liquid I, add 5000 milliliters of distilled water in medicinal residues, decocting boils into 1000 milliliters medicinal liquid II; After taking out medicinal liquid II, 4000 milliliters of adding distil waters in medicinal residues again, the decocting boiling down is condensed to 1000 milliliters medicinal liquid III, takes out medicinal liquid III; 2000 milliliters of medicinal liquid I, 1000 milliliters of medicinal liquid II, 1000 milliliters of medicinal liquid III are mixed, decoct into 1000 milliliters of concentrated solution IV, adopt filter pump or filter ball filtering and concentrating liquid IV then; (3) add 1000 milliliters of 75% ethanol among the concentrated solution IV after filtering then, left standstill 24 hours, the impurity that precipitates is filtered out with filter paper or filter cloth, the reuse distillator is with 1000 milliliters of alcohol reflux; Gained suspension decocting and concentrating to every milliliter of suspension is contained crude drug 5 grams, crude drug in whole is totally 4000 grams, is 800 milliliters so concentrate the suspension that obtains again; (4) 800 milliliters of suspensions are dried to behind the pasty state ointment with behind granular medicament I, 15 gram zinc sulfate, 150 gram activated calciums, the 135 gram vitamin E mix homogeneously and dry, be ground into again Powdered, the capsule of packing into No. 0.Every capsule is 0.3 gram, 4.5 milligrams on sulfur acid zinc, 45 milligrams of activated calciums, 40 milligrams of vitamin Es.
Consumption of the present invention and usage are: each 2-4 grain, 2 times on the one, respectively once, boiled water takes sooner or later.10 days is a course of treatment, and the lighter 3-4 course of treatment, weight person 5-6 just can thoroughly cure a course of treatment.Period in a medicine is avoided irritable foods such as acid, peppery, wine, avoids antipsychotic drug, as Western medicine tranquilizer etc.

Claims (2)

1. medicament capsule for the treatment of male infertility, it is characterized in that: it has following composition and quality percentage composition: Colla cornus cervi 2-4%, Colla Plastri Testudinis 2-3%, Testis et penis callorhini 2-4%, Placenta Hominis 2-4%, goat testis 2-4%, Gecko 2-3%, Ovum Gallus domesticus album (drying) 2-4%, Stigma Croci 2-4%, Flos Lonicerae 4-5%, Radix Salviae Miltiorrhizae 6-8%, Radix Clematidis 6-8%, Herba Epimedii 5-8%, Radix Morindae Officinalis 4-6%, Fructus Psoraleae 4-6%, Fructus Corni 4-6%, Fructus Lycii 4-8%, Semen Cuscutae 4-6%, Fructus Schisandrae Chinensis 4-6%, Fructus Rubi 4-6%, Fructus Rosae Laevigatae 4-6%, Semen Allii Tuberosi 6-8%, Rhizoma Curculiginis 5-8%, Herba Cynomorii 4-6%, Herba Cistanches 6-10%, zinc sulfate 0.3-0.4%, activated calcium 3-4%, vitamin E2 .7-3%.
2. the production method of medicament capsule according to claim 1 is: (1) will grind and be smalls earlier by the good Colla cornus cervi of quality proportioning, Colla Plastri Testudinis, Testis et penis callorhini, Placenta Hominis, goat testis, Gecko, Ovum Gallus domesticus album (drying) seven flavor Chinese medicines, be compressed into granular medicament I; (2) Stigma Croci that will be good by weight ratio, Flos Lonicerae, Radix Salviae Miltiorrhizae, Radix Clematidis, Herba Epimedii, Radix Morindae Officinalis, Fructus Psoraleae, Fructus Corni, Fructus Lycii, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Rubi, Fructus Rosae Laevigatae, Semen Allii Tuberosi, Rhizoma Curculiginis, Herba Cynomorii, Herba Cistanches totally ten seven flavor Chinese medicines add distilled water, the decocting boiling down shortens medicinal liquid I into; After taking out medicinal liquid I, add distilled water in former medicinal residues, the decocting boiling down shortens medicinal liquid II into, takes out medicinal liquid II; Add distilled water again in medicinal residues, the decocting boiling down shortens medicinal liquid III into, takes out medicinal liquid III; Medicinal liquid I, II, the III of three taking-ups are mixed, decoct into concentrated solution IV; With filter pump or filter ball filtering and concentrating liquid IV; (3) add ethanol then in concentrated solution IV, leave standstill, filter, with alcohol reflux, gained suspension reconcentration to every milliliter of suspension contains crude drug 4-6 gram by distillation; (4) suspension after will concentrating is dried to ointment; Ointment, granular medicament I, by the be mixed back oven dry of the good zinc sulfate of quality proportioning, activated calcium, vitamin E, be ground into Powdered, the O capsule of packing into.
CN 200410010110 2004-03-03 2004-03-03 Medicine capsule for treating male infertility Expired - Fee Related CN1284586C (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101352520B (en) * 2008-09-24 2011-01-19 南京中医药大学 Sperm-nourishing capsules for treating male sexual disfunction and preparation method thereof
CN103638493A (en) * 2013-12-10 2014-03-19 张朝兰 Medicine for treating male infertility and preparation method of medicine
CN106421172A (en) * 2016-12-25 2017-02-22 胡丽萍 Combinational traditional Chinese medicine for curing male infertility

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101352520B (en) * 2008-09-24 2011-01-19 南京中医药大学 Sperm-nourishing capsules for treating male sexual disfunction and preparation method thereof
CN103638493A (en) * 2013-12-10 2014-03-19 张朝兰 Medicine for treating male infertility and preparation method of medicine
CN103638493B (en) * 2013-12-10 2015-07-01 张朝兰 Medicine for treating male infertility and preparation method of medicine
CN106421172A (en) * 2016-12-25 2017-02-22 胡丽萍 Combinational traditional Chinese medicine for curing male infertility

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