The purpose of this invention is to provide a kind of medicine for the treatment of the analgesic hemostatic antipruritic antibacterial, but especially to the pain relieving of having a toothache, to pulpitis, pericoronitis, gingival hemorrhage, oral cavity burst pain, positive effect is arranged, particularly to have tooth pulled out back hemostasis, infection, avoid dry socket and postoperative wound that the remarkable result that promotes healing is arranged.The characteristics of this preparation be relieve the pain, hemostasis, antipruritic, antibacterial effect is obvious, the wound good film-forming property can well protect skin to avoid the medicine of environmental stimuli, curative effect height of the present invention, short treating period is cured highly, has no side effect.
The present invention adopts following principle to realize: the present invention adopts its effect of propolis and foundation: people use existing thousands of years of propolis, and the pontifex of ancient Egypt is being grasped the method for medicine, chemistry and system mummy, and they have gained some understanding to the anti-corrosive properties of propolis.The ancient Greek and the Roman Empire are all relevant for the record of propolis.The beginning of this century, during Knickerbocker African and British boer war (1889-1902), just once adopted " propolis vaseline " treatment wound, (1902) and think that it has the effect that promotes tissue regeneration, (1923) former Soviet Union also uses propolis ointment to control wound during patriotic war in a large number.Gigawatt Er Jinna (1947-1948) has carried out systematic study to the antibacterial activity of propolis, he finds that propolis is to staphylococcus aureus, Ba Deshi bacillus and necrosis in the gram negative bacterias such as Staphylococcus albus, Hemolytic streptococcus, bacillus rhusiopathiae suis, bacillus subtilis, charcoal subcutaneous ulcer bacillus, the bacteriostatic activity of bacillus is also very strong.La Wei (1960) finds propolis to bacillus subtilis, and proteus vulgaris and honeybee epidemic disease bacillus cereus have antibiotic property, thinks that antibacterial activity is mainly from the galangin and the pinocembrin of propolis.Ka Limowa (1961-1963) claims that propolis has the activity of anti-acid-fast bacillus, available propolis treatment tuberculosis.People (1970) such as Welland girl baby year proposition, isolating pinocembrin has very strong antibiotic property from propolis.Maze people (1975) such as is received and is detected the resistance of the various compositions of propolis to bacillus subtilis, staphylococcus aureus, colibacillus, and thinking has remarkable antibiotic property to a tonkabean acid benzyl ester and a kind of caffeic acid fat by 3-acetyl pinobanksin.Woods Deng Feierze (1976) gathers 15 propolis samples from the different local Various Seasonal of the U.S., measure in the antibacterial with its extract, 25 kinds have strong restraint, comprising bacillus larvae, Gram-negative coccus and acid-fast bacilli, other has 7 kinds of gram negative bacilli to be suppressed, and has 20 kinds to be suppressed in the fungus of 39 kinds of tests.He finds that Trichophyton has sensitivity to propolis, uses propolis treatment Trichophyton to provide foundation as dermatosis.He thinks that the caffeic acid in the propolis has antibiotic property to staphylococcus aureus, Bacillus proteus, tuberculosis mycobacterium and fungus.People such as the pillars of a house (1984) experimental results show that alcohol immersion of 1%-10% propolis or ether immersion to the achorion in the common medical mycology with paper dish method, and red mentagrophytes, floccus mentagrophyte, Microsporum ferrugineum, Microsporum gypseum, ulotrichy pityrosporion ovale, trichophyton tonsurans, brain shape tinea bacterium, purple tinea bacterium etc. all have stronger bacteriostasis.People such as A Weiduo (1974) point out, with flavonoid one eriodictyol, can prevent and treat because the acute PI that respiratory tract burn thoracic trauma and shock cause.Luo Jie (1988) points out, flavonoid in the propolis helps the healing of gastric ulcer, improve PI: play an important role to strengthening blood capillary, can prevent and treat vitamin C deficiency with vitamin C is collaborative, propolis is similar to the antioxidation of many flavonoid, can remove free radical, therefore, propolis has no side effect.The present invention adopts its effect of ethanol and foundation: the solubilized propolis also has antiinflammation.The present invention adopts Oleum Caryophylli, and it has pain relieving, is good for the stomach, antibiotic, deodorization, antisepsis.The present invention has the medicine of the effect that promotes tissue regeneration, and the present invention has antibiotic property, to staphylococcus aureus.Hemolytic streptococcus, bacillus rhusiopathiae suis, the bacteriostatic activity of estimating Ahmedabad in gram, the negative bacterium such as careless bacillus, charcoal subcutaneous ulcer bacillus and gangrenosum acne bacillus are also very strong.Bacillus subtilis, P. vulgaris and honeybee epidemic disease bacillus cereus there are resistance, think that antibacterial activity is mainly also very strong.Bacillus subtilis, proteus vulgaris and honeybee epidemic disease bacillus cereus are had resistance, can be used for treating tuberculosis, pinocembrin has very strong antibiotic property.Various compositions are to bacillus subtilis, staphylococcus aureus, escherichia coli have resistance, think 3-acetyl pinobanksin, have significantly antibiotic to a tonkabean acid benzyl ester and a kind of caffeic acid fat, mensuration is in the antibacterial, and 25 kinds of strong restraints are comprising plumelet spore bacillus, Gram-negative coccus and acid-fast bacilli, the inhibition that other has 7 kinds of gram negative bacilli to be subjected to, have 20 kinds and be suppressed in the fungus of 39 kinds of tests, finding has sensitivity to Trichophyton, for dermatosis provides foundation.To the little spore bacterium of the achorion/red mentagrophytes in the common fungus/floccus mentagrophyte rust, microsporon gypseum, ulotrichy pityrosporion ovale, trichophyton tonsurans, brain shape tinea bacterium, purple tinea bacterium has stronger inhibitory action.Flavonoid one eriodictyol can be prevented and treated because the acute pulmonary insufficiency that respiratory tract burn and shock cause.Flavonoid helps the healing of gastric ulcer, improves PI, works the effect of being sought after to strengthening blood capillary, with the collaborative vitamin C deficiency of preventing and treating of vitamin C, similar to the antioxidation of many flavonoid, can remove free radical, the medicine principle cooperation that therefore has no side effect realizes.
Owing to adopting such scheme, can make analgesic hemostatic antipruritic antibacterial of the present invention, especially can reach 99% to toothache pain relieving effective percentage, healing can reach more than 98.6%, to the remarkable result of having tooth pulled out back hemostasis, infection, avoiding dry socket and postoperative wound to have promotion to heal.The characteristics of this preparation be relieve the pain, hemostasis, antipruritic, antibacterial effect is obvious, the wound good film-forming property can well protect skin to avoid the medicine of environmental stimuli.