CN1546102A

CN1546102A - Pain alleviating plaster for periarthritis humeroscapularis and its preparation

Info

Publication number: CN1546102A
Application number: CNA2003101110994A
Authority: CN
Inventors: 吴昊峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2003-12-02
Filing date: 2003-12-02
Publication date: 2004-11-17
Anticipated expiration: 2023-12-02
Also published as: CN1240434C

Abstract

The invention relates to a plaster for treating periarthritis humeroscapularis and process for its preparation, which is an emplastrum preparation made from curcuma longa, Clematis chinensis, frankincense, myrrh, and borneol.

Description

Plaster for periarthritis of shoulder joint and preparation technology thereof

Technical field: the present invention is a kind of plaster for periarthritis of shoulder joint and preparation technology thereof, belongs to technical field of Chinese medicines.

Technical background: scapulohumeral periarthritis, shoulder numbness are more common in middle-older patient, with suffer from a deficiency of the kidney, insufficiency of vital energy and blood is basis, wind-cold damp pathogen invasion and attack are for marking.Because of pathogen obturation, QI and blood obstructed, joint involvement, meridians impatency, venation lose and support is the basic of pathogenesis, is a kind of commonly encountered diseases, frequently-occurring disease, particularly crowd's above middle age sickness rate is than higher, present stage, doctor trained in Western medicine can only be carried out pain relieving by playing sealing less than effective especially Therapeutic Method and medicine for this disease, relatively misery and effect are limited during this method patient treatment, and the time is of short duration; The Chinese Minority Nationalities area have some traditional medicines can treat this disease such as, application number is 981122035 " plaster for periarthritis of shoulder joint ", the effect that just has treatment, just the Chinese medicine medicine is useful for some crowds, but stress results and not obvious for the others, the generation of this species diversity is a more complicated, so need market to provide a greater variety of medicines to select for use for the patient.

Summary of the invention: the objective of the invention is to: the proved recipe handed down from one's ancestors, research, the exploitation that are used for the treatment of " scapulohumeral periarthritis ", arthralgia-syndrome pain according to ethnic groups is among the people the southwest of Guizhou Province, Guizhou Province area provide plaster for periarthritis of shoulder joint and preparation technology thereof; The present invention constitutes like this: plaster for periarthritis of shoulder joint is to calculate according to composition by weight, is made into the plaster preparation by Rhizoma Curcumae Longae 400-800g, Radix Clematidis 300-500g, Radix Zanthoxyli Spinifolii 300-500g, Olibanum 60-130g, Myrrha 60-130g, Borneolum Syntheticum 30-70g; Specifically: calculate according to composition by weight, it is made into the plaster preparation by Rhizoma Curcumae Longae 600g, Radix Clematidis 450g, Radix Zanthoxyli Spinifolii 450g, Olibanum 100g, Myrrha 100g, Borneolum Syntheticum 50g; The preparation technology of this plaster for periarthritis of shoulder joint is according to given ratio, with Rhizoma Curcumae Longae, Radix Clematidis adds the alcohol reflux that 6-10 doubly measures, filter merging filtrate, decompression recycling ethanol, aqueous solution is standby, medicinal residues decoct with water, and collecting decoction filters, filtrate and aqueous solution merge, be concentrated in the time of 80 ℃ relative density and be 1.25 clear paste, Radix Zanthoxyli Spinifolii, Olibanum, Myrrha adds the alcohol reflux that 8-12 doubly measures to be carried, and filters, merging filtrate, decompression recycling ethanol is concentrated in the time of 80 ℃ relative density and is 1.25 extractum, merges above-mentioned two kinds of extractum that obtain, add Borneolum Syntheticum after cooling, mixing adds rubber again, Colophonium, zinc oxide, lanoline, in the substrate that vaseline is made, make coating, be coated with cream, cut off, the lid lining, punching, cut into slices, promptly;

Say: with Rhizoma Curcumae Longae 600g more specificly, Radix Clematidis 450g adds 8 times of amount alcohol reflux of 80% 3 times, each 1 hour, filter, merging filtrate, decompression recycling ethanol, aqueous solution is standby, medicinal residues add 10 times of water gagings and decoct 2 times, each 1 hour, collecting decoction filtered with 1.2 μ m microporous filter membrane, filtrate and aqueous solution merge, be concentrated in the time of 80 ℃ relative density and be 1.25 clear paste, Radix Zanthoxyli Spinifolii 450g, Olibanum 100g, Myrrha 100g adds 10 times of amount 60% alcohol reflux 3 times, each 1 hour, filter, merging filtrate, decompression recycling ethanol is concentrated in the time of 80 ℃ relative density and is 1.25 extractum, merge above-mentioned two kinds of extractum, add Borneolum Syntheticum 50g after cooling, mixing adds rubber, Colophonium, zinc oxide, lanoline, in the substrate that vaseline is made, make coating, be coated with cream, cut off, the lid lining, punching, be cut into 1000, specification is 7 * 10cm, promptly.

Scapulohumeral periarthritis, shoulder numbness many because of pathogen obturation, QI and blood obstructed, joint involvement, the meridians impatency, venation is lost and is supported basic for pathogenesis, so treatment be the medical knowledge of its rule of treatment with eliminating evil active, relieving spasm to stop pain, in conjunction with new disease at warp, pathogen usually intruding into collateral in protracted disease, deficiency of vital energy insufficiency of blood promotes unablely, causes the rule of qi depression to blood stasis; With Rhizoma Curcumae Longae tool suffering, hardship, temperature, return spleen, Liver Channel, the removing blood stasis circulation of qi promoting is arranged, the effect of removing obstruction in the collateral to relieve pain is a monarch drug.Compendium of Material Medica: " (Rhizoma Curcumae Longae) controls the migratory arthralgia brachialgia "; Radix Zanthoxyli Spinifolii, hot, little hardship, the tool expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain is ministerial drug." classification medical herbs ": " (Radix Zanthoxyli Spinifolii) loose blood dispelling the stagnated QI, control the pathogenic wind-warm bones and muscles pain "; Radix Clematidis, hot, salty, warm, return urinary bladder channel, the tool expelling wind and removing dampness, removing obstruction in the collateral to relieve pain is ministerial drug; " medicine justice ": " Radix Clematidis, property are anxious suddenly, are apt to away and do not keep, and should lead to twelve channels and collaterals, cure mainly wind, wet, expectorant is stopped up the meridians that stagnate, and cause into gout and walk, or swell through, arthralgia, or numbness; " Olibanum, hot, bitter, warm, return liver, the heart, spleen channel; Myrrha, bitter, hot, flat, GUIXIN, liver, spleen channel.Two medical instrument promoting blood circulation and stopping pain, the merit of detumescence and promoting granulation is adjuvant drug altogether; Compendium of Material Medica: " Olibanum is invigorated blood circulation, and the Myrrha blood that looses all can alleviating pain and detumescence life, uses so two medicines are often held concurrently mutually "; Borneolum Syntheticum, suffering, hardship, be slightly cold the have one's ideas straightened out merit of pain of detumescence of GUIXIN, spleen, lung meridian, tool; " medical center bun want ": " property is walked and is not kept for the Borneolum Syntheticum master stagnated fire of loosing, the deep heat of energy, also can the life pain relieving; " Borneolum Syntheticum be slightly cold still can the side of supervising in the temperature of his medicine, warm biased of unlikely appearance is so make medication for assistant; All medicines share, and play expelling wind and removing dampness altogether, blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain; The adaptation disease is scapulohumeral periarthritis and the shoulder arthralgia due to shoulder numbness, the evil stasis of blood are tied mutually, praises the limited disease that Dengs.

Compared with prior art: formula for a product formation provided by the invention is fairly simple, production technology is uncomplicated, product quality is convenient to control, and plaster for periarthritis of shoulder joint is a topical administration, directly is attached at the pathological changes shoulder joint, medicine percutaneous skin is absorbed up to reaching diseased region, just can reach therapeutic purposes; Have easy to use, steady quality, it is fast to improve symptom, characteristics such as be easy to carry.This product side medicine is formed and both to have been embodied the traditional characteristics that Chinese medicine is controlled numbness, absorbs the practical experience of controlling numbness among the people again, in both having embodied in the prescription

Cure to treat medical knowledge and the rule of treatment of numbness disease, showed the characteristic that national medication is sent an expedition against again simultaneously, think no matter the arthromyodynia due to which kind of reason based on dispelling cold by warming the meridian, expelling wind and removing dampness, by coagulation of QI-blood, due to network road numbness hinders, stagnation of QI and blood may bring about pain; Therefore, " blood stasis dispelling " becomes the another cardinal principle of treatment arthromyodynia, and " Radix Zanthoxyli Spinifolii " has expelling wind and removing dampness for the medicine of commonly using treatment shoulder numbness pain among the people in the side, blood circulation promoting and blood stasis dispelling, and the effect of reducing swelling and alleviating pain has promptly embodied this characteristic.It is better that this product prescription is formed the flavour of a drug safety: the treatment arthromyodynia locate to use Chinese medicine preparation, generally contain the bigger flavour of a drug of toxicity such as Radix Aconiti, Radix Aconiti Kusnezoffii or Semen Strychni more, be difficult to adhere to life-time service, contained drug in this product, no obvious toxic-side effects, but clinical life-time service, safety is better.

Embodiments of the invention 1: with Rhizoma Curcumae Longae 600g, Radix Clematidis 450g adds 8 times of amount alcohol reflux of 80% 3 times, each 1 hour, filter, merging filtrate, decompression recycling ethanol, aqueous solution is standby, medicinal residues add 10 times of water gagings and decoct 2 times, each 1 hour, collecting decoction filtered with 1.2 μ m microporous filter membrane, filtrate and aqueous solution merge, be concentrated in the time of 80 ℃ relative density and be 1.25 clear paste, Radix Zanthoxyli Spinifolii 450g, Olibanum 100g, Myrrha 100g adds 10 times of amount 60% alcohol reflux 3 times, each 1 hour, filter, merging filtrate, decompression recycling ethanol is concentrated in the time of 80 ℃ relative density and is 1.25 extractum, merge above-mentioned two kinds of extractum, add Borneolum Syntheticum 50g after cooling, mixing adds rubber, Colophonium, zinc oxide, lanoline, in the substrate that vaseline is made, make coating, be coated with cream, cut off, the lid lining, punching, be cut into 1000, specification is 7 * 10cm, promptly.

Embodiments of the invention 2: present embodiment is made into the plaster preparation by Rhizoma Curcumae Longae 400g, Radix Clematidis 300g, Radix Zanthoxyli Spinifolii 300g, Olibanum 60g, Myrrha 60g, Borneolum Syntheticum 30g; Specifically: with Rhizoma Curcumae Longae, Radix Clematidis adds 75% alcohol reflux of 6 times of amounts, filter, merging filtrate, decompression recycling ethanol, aqueous solution is standby, and medicinal residues decoct with water, collecting decoction, filter, filtrate and aqueous solution merging are concentrated in the time of 80 ℃ relative density and are 1.25 clear paste, Radix Zanthoxyli Spinifolii, Olibanum, Myrrha adds 85% alcohol reflux of 8 times of amounts and carries, filter merging filtrate, decompression recycling ethanol, be concentrated in the time of 80 ℃ relative density and be 1.25 extractum, merge above-mentioned two kinds of extractum that obtain, add Borneolum Syntheticum after cooling, mixing, add rubber again, Colophonium, zinc oxide, lanoline, in the substrate that vaseline etc. are made, make coating, be coated with cream, cut off, the lid lining, punching, cut into slices, promptly;

Embodiments of the invention 3: make of Rhizoma Curcumae Longae 800g, Radix Clematidis 500g, Radix Zanthoxyli Spinifolii 500g, Olibanum 130g, Myrrha 130g, Borneolum Syntheticum 70g, Rhizoma Curcumae Longae, Radix Clematidis are added 90% alcohol reflux of 10 times of amounts, filter, merging filtrate, decompression recycling ethanol, aqueous solution is standby, medicinal residues decoct with water, collecting decoction filters, and filtrate and aqueous solution merge, be concentrated in the time of 80 ℃ relative density and be 1.25 clear paste, 65% alcohol reflux that Radix Zanthoxyli Spinifolii, Olibanum, Myrrha is added 12 times of amounts is carried, and filters, and merges filter

Liquid, decompression recycling ethanol, be concentrated in the time of 80 ℃ relative density and be 1.25 extractum, merge above-mentioned two kinds of extractum that obtain, add Borneolum Syntheticum after cooling, mixing, add again in the substrate that rubber, Colophonium, zinc oxide, lanoline, vaseline makes, make coating, be coated with cream, cut-out, lid and serve as a contrast, punch, cut into slices, promptly;

Clinical verification, curative effect is obvious.Example: certain woman, 54 years old, long-term shoulder arthralgia, behavior inconvenience, seeking medical advice is diagnosed as scapulohumeral periarthritis, examines to its " plaster for periarthritis of shoulder joint " 10 and pastes, and paste every day one, further consultation after ten days, the symptom complete obiteration is raised one's hand freely.

" plaster for periarthritis of shoulder joint " clinical verification 100 routine curative effects through making are added up in following:

(10 paste a course of treatment)

Sex recovery from illness produce effects is invalid

Man 16 22 7

Woman 24 21 10

Reaching 83% from 100 routine clinical use " plaster for periarthritis of shoulder joint " effective percentage, is treatment scapulohumeral periarthritis and the preferable product of shoulder arthralgia.

Claims

1, a kind of plaster for periarthritis of shoulder joint is characterized in that: calculate according to composition by weight, it is made into the plaster preparation by Rhizoma Curcumae Longae 400-800g, Radix Clematidis 300-500g, Radix Zanthoxyli Spinifolii 300-500g, Olibanum 60-130g, Myrrha 60-130g, Borneolum Syntheticum 30-70g.

2, according to the described plaster for periarthritis of shoulder joint of claim 1, it is characterized in that: calculate according to composition by weight, it is made into the plaster preparation by Rhizoma Curcumae Longae 600g, Radix Clematidis 450g, Radix Zanthoxyli Spinifolii 450g, Olibanum 100g, Myrrha 100g, Borneolum Syntheticum 50g.

3, according to claim 1, the preparation technology of 2 described this plaster for periarthritis of shoulder joint, it is characterized in that: according to given ratio, with Rhizoma Curcumae Longae, Radix Clematidis adds the alcohol reflux that 6-10 doubly measures, and filters, merging filtrate, decompression recycling ethanol, aqueous solution is standby, and medicinal residues decoct with water, collecting decoction, filter, filtrate and aqueous solution merging are concentrated in the time of 80 ℃ relative density and are 1.25 clear paste, Radix Zanthoxyli Spinifolii, Olibanum, Myrrha adds the alcohol reflux that 8-12 doubly measures and carries, filter merging filtrate, decompression recycling ethanol, be concentrated in the time of 80 ℃ relative density and be 1.25 extractum, merge above-mentioned two kinds of extractum that obtain, add Borneolum Syntheticum after cooling, mixing, add rubber again, Colophonium, zinc oxide, lanoline, in the substrate that vaseline is made, make coating, be coated with cream, cut off, the lid lining, punching, cut into slices, promptly.

4, preparation technology according to the described plaster for periarthritis of shoulder joint of claim 3, it is characterized in that: with Rhizoma Curcumae Longae 600g, Radix Clematidis 450g adds 8 times of amount alcohol reflux of 80% 3 times, each 1 hour, filter merging filtrate, decompression recycling ethanol, aqueous solution is standby, and medicinal residues add 10 times of water gagings and decoct each 1 hour 2 times, collecting decoction, filter with 1.2 μ m microporous filter membrane, filtrate and aqueous solution merging are concentrated in the time of 80 ℃ relative density and are 1.25 clear paste, Radix Zanthoxyli Spinifolii 450g, Olibanum 100g, Myrrha 100g adds 10 times of amount 60% alcohol reflux 3 times, each 1 hour, filter merging filtrate, decompression recycling ethanol, be concentrated in the time of 80 ℃ relative density and be 1.25 extractum, merge above-mentioned two kinds of extractum, add Borneolum Syntheticum 50g after cooling, mixing, add rubber, Colophonium, zinc oxide, lanoline, in the substrate that vaseline is made, make coating, be coated with cream, cut off, the lid lining, punching, be cut into 1000, specification is 7 * 10cm, promptly.