CN1539492A - Medication for treating astriv disease, gastric ulcer and preparation technique - Google Patents
Medication for treating astriv disease, gastric ulcer and preparation technique Download PDFInfo
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- CN1539492A CN1539492A CNA2003101108299A CN200310110829A CN1539492A CN 1539492 A CN1539492 A CN 1539492A CN A2003101108299 A CNA2003101108299 A CN A2003101108299A CN 200310110829 A CN200310110829 A CN 200310110829A CN 1539492 A CN1539492 A CN 1539492A
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- seu herba
- rhizoma seu
- herba bergeniae
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Abstract
A Chinese medicine 'Yunweining capsule' for treating gastral cavity pain, acute or chronic gastritis, atrophic or superficial gastritis, gastric or duodenal ulcer, gastrorrhagia and gastrospasma is disclosed. Its advantages are high curative effect (96% or more) and high safety.
Description
Technical field
The present invention relates to a kind of be used for the treatment of gastropathy and gastric ulcer Yi nationality, distributed over Yunnan, Sichuan and Guizhou's national folk medicine---the cloud stomach is peaceful, especially for treatment gastric abscess, acute or chronic gastritis, atrophic, superficial gastritis, gastric and duodenal ulcers, stomach spasm, the Chinese herbal medicine of gastrorrhagia etc., especially obvious especially to cold-condensing type gastric abscess effect.
Background technology
The Chinese medicine and western medicine kind of the above-mentioned gastropathy of existing treatment is tired many, and curative effect is also suitable because of the people, but some medicine side effect is bigger.
Summary of the invention
Yi nationality, distributed over Yunnan, Sichuan and Guizhou's medicine is magnificent wonderful work in the pools of traditional Chinese medicine, and especially in border area, motherland southwest, the Yis generations that live in sad labor mountain range understand with natural plants and treat disease, thereby guaranteed multiplying and being prosperous of this nationality.The cloud stomach rather promptly is one of Yi nationality, distributed over Yunnan, Sichuan and Guizhou's medicine, in order to impel us to the further systematic study of ethnic drug, makes it that one seat be arranged in Chinese medicine, and brings benefit to the mankind.
The medicine that is used for the treatment of gastropathy and gastric ulcer, the Rhizoma Seu Herba Bergeniae that it is processed by Folium daturae that steams and stir-fry is formed Folium daturae by weight ratio: Rhizoma Seu Herba Bergeniae=1: 1.Its preparation technology is: Folium daturae, choose clean, and avoid washing, be placed in the rice steamer; Earlier water in the end pot is heated to boiling, the rice steamer of putting the Folium daturae of packing into thereon continues to reduce to 90 ℃ after Zeng Ding emits steam and steamed 30 minutes being heated to more than 95 ℃, opens Zeng Gai rapidly and removes, take out Folium daturae, 40～60 ℃ of oven dry, fine ground powder is crossed 100 mesh sieves, and is standby.Rhizoma Seu Herba Bergeniae, choose clean, be cut into the segment of 1 centimeter length, by weight ratio Rhizoma Seu Herba Bergeniae: Endoconcha Sepiae powder=1: 0.3 ratio, drop in the Endoconcha Sepiae powder that is heating, stir constantly, Rhizoma Seu Herba Bergeniae is fried to yellow skin but when not burnt, pulled out with skimming ladle, cool, sieve removes the Endoconcha Sepiae powder, Rhizoma Seu Herba Bergeniae is ground into fine powder cross 100 mesh sieves, and is standby.To steam and fry the Folium daturae powder and the Rhizoma Seu Herba Bergeniae powder of processing, even by 1: 1 mixed, cross 100 mesh sieves, filling is made capsule or mixed powder granulation filling is become capsule.
The medicine that is used for the treatment of gastropathy and gastric ulcer---YUNWEINING capsule, the employing natural plants is made, safe, in our province province institute of traditional Chinese medicine and the traditional Chinese medical science kind clinical practice of province the People's Hospital, 193 routine cases have been observed, the gastric abscess curative effect of treatment gastric abscess, particularly cold-condensing type is obvious, and total effective rate reaches more than 96%.Side effect in addition, is made hemogram and is observed except the sensation of xerostomia (about incidence rate of about 50%, and how occurring in 1～2 hour in the back of taking medicine continues spontaneous remission after 2 hours), and the some cases of liver, kidney function test does not have unusual significantly before and after medication.
Description of drawings
Fig. 1 is the preparation technology's flow chart that is used for the treatment of the medicine of gastropathy and gastric ulcer
Fig. 2～Fig. 4 is a gastric film slice map behind the animal experiment
The specific embodiment
The medicine that is used for the treatment of gastropathy and gastric ulcer, the Rhizoma Seu Herba Bergeniae that it is processed by Folium daturae that steams and stir-fry is formed Folium daturae by weight ratio: Rhizoma Seu Herba Bergeniae=1: 1.Its preparation technology is: Folium daturae, choose clean, and avoid washing, be placed in the rice steamer; Earlier water in the end pot is heated to boiling, the rice steamer of putting the Folium daturae of packing into thereon continues to reduce to 90 ℃ after Zeng Ding emits steam and steamed 30 minutes being heated to more than 95 ℃, opens Zeng Gai rapidly and removes, take out Folium daturae, 40～60 ℃ of oven dry, fine ground powder is crossed 100 mesh sieves, and is standby.Rhizoma Seu Herba Bergeniae, choose clean, be cut into the segment of 1 centimeter length, by weight ratio Rhizoma Seu Herba Bergeniae: Endoconcha Sepiae powder=1: 0.3 ratio, in the 30kg Endoconcha Sepiae powder that 100kg Rhizoma Seu Herba Bergeniae input is being heated, stir constantly, Rhizoma Seu Herba Bergeniae is fried to yellow skin but when not burnt, pulled out with skimming ladle, cool, sieve removes the Endoconcha Sepiae powder, Rhizoma Seu Herba Bergeniae is ground into fine powder cross 100 mesh sieves, and is standby.To steam and fry the Folium daturae powder and the Rhizoma Seu Herba Bergeniae powder of processing, respectively get 100 gram mix homogeneously, cross 100 mesh sieves, filling is made 1000 of capsules or mixed powder granulation filling is become 1000 of capsules.Every content of dispersion 0.2 gram, oral, 3 times on the one, one time 1～2.
Flos Daturae, (Datura stramonium) also claims " wind eggplant ".Solanaceae.Annual poisonous draft.Stem is upright, Chang Erqi shape branch.Leaf alternate, oval, edge are irregular wavy division.Xia Qiu is bloomed, the corolla funnel-form, and white, between single leave axil or branch fork, the capsule oval has not isometric spine, and pintongs splits when ripe.Originate in the torrid zone or subtropical zone, all there is distribution China southwest to the southeast, wild or cultivation.Chinese medicine is used as medicine with flower, leaf or the seed of Flos Daturae, flower name " upright datura flower ", " Flos Daturae ", and warm in nature, acrid in the mouth, function is relievingd asthma, pain relieving, cures mainly diseases such as cough with dyspnea asthma, stomachache, and the seed of datura claims " wind Fructus Solani melongenae " external dispelling the wind and dampness pathogens arthralgia pain etc.Leaf, flower and seed contain hyoscyamine, scopolamine etc., as anticholinergic agent, act on similar to Semen daturae.Flower or Herb have severe toxicity, and taking should be careful, can not be excessive.Folium daturae is plucked between 7～August and is processed this product powder green or celadon.(" Guangxi Chinese crude drug standard " 1996 version second 217～218 pages)
Rhizoma Seu Herba Bergeniae, the holder of the blue flower of another name rock, Rhizoma Bergeniae purpurascentis, Rhizoma Seu Herba Bergeniae etc.Perennial herb normal paste ground and gives birth to, and is high 20～30 centimetres, all smooth nothings mao.Rhizome is thick, horizontal walk, and the footpath can reach 3 centimetres, the outside pitchy, inner face white is bronzing after doing, and internode is short, and indefinite fibrous root is arranged on the joint, and every joint has petiole base to be expanded into the sheath shape to deposit in the residue place.Single leafage gives birth to, the normal ground that pastes, meat and thick, obovate or oblong, long 8～16 centimetres, wide 5～10 centimetres, tip is blunt, and the wide wedge shape of base portion is to circular, and there is wavy little sawtooth at the edge, top bottle green, often redly, glossy, following light green also often redly, is abound with the little den of gland shape, petiole is sturdy, long 2.5～7 centimetres.Bloom summer, long 15～20 centimetres of scape, and umbrella room locusta, the corolla pink, calyx 5 drastic cracks, the bottom symphysis becomes cup-shaped.Capsule 5 splits.Nature and flavor are sweet, and are little puckery, cold.Clear detoxifcation brimful of tears, blood-arresting catamenia-regulating, relaxing muscles and tendons to promote blood circulation.Cure mainly traumatic injury, rheumatalgia, dysmenorrhoea, leucorrhea, dysfunctional uterine hemorrhage, enteritis, dysentery, the pulmonary tuberculosis cough, spitting of blood is spitted blood epistaxis, gastrointestinal hemorrhage etc.[Kunming Inst. of Botany, Chinese Academy of Sciences publishes the 300th page on pearl " choosing of Yunnan Chinese herbal medicine " (sequel)]
The inner shell of Endoconcha Sepiae ， Wei Quarry section's animal sepiella maindroni de Rochebrune or golden cuttlefish.Salty, puckery, tepor.Be used for astringing to arrest bleeding: control metrorrhagia, gastric hemorrhage epistaxis, traumatic hemorrhage; Relieving gastric hyperacidity to alleviate stomachache: control gastric duodenal ulcer, stomachache acid regurgitation water; Removing dampness is held back skin ulcer; Relieving leukorrhea by astringents.(Fujian science tech publishing house 2002 version " pocket Chinese herbal medicine color atlas " the 674th page)
Get body weight 150～180g SD rat, water is can't help in fasting, is divided into 3 groups behind the 24h at random, and 10 every group, the peaceful 0.05g/kg of cloud stomach (low dose group), 0.2g/kg (high dose group) and matched group thunder Buddhist nun fourth 0.05g/kg group.Each treated animal is all irritated stomach with the 1ml/100g body weight, 1 time/d, is total to 7d.Behind the slight anesthetized rat of ether, its clinostatism is fixed on the rat fixation steel plate, and the animal that will fix is with soft metal net appropriateness one week of parcel.After last is irritated stomach 30min with fixed rat uprightly be dipped in 23 ℃ thermostatic water bath not, the water surface is advisable with neat xiphoid-process.Take off neck continuously behind the 24h and put to death, open the abdominal cavity, get stomach behind ligation pylorus and the cardia.Inject the 6ml normal saline by gastric gland portion, put it in 1% formalin fixedly 10min, cut off along greater gastric curvature again.Can find out obviously that from the photo of testing the gastric mucosa of taking the peaceful rat of cloud stomach is level and smooth, high dose group especially takes that to take the effect of ranitidine than matched group much better.
Being used for clinical 103 example observation cases in hospital is, belongs to stagnation of QI disease 8 examples according to Chinese medical discrimination, deficiency-cold symptoms 55 examples, and cold coagulation disease 19 examples, blood stasis disease 21 examples, therapeutic outcome: effective 99 examples, 4 examples are invalid, and all show effect within a short period of time.Stagnation of QI disease 1 example is arranged in invalid 4 examples, and the course of disease 12 years is female patient, 31 years old; Deficiency-cold symptoms 2 examples, the 1 routine course of disease 13 years, the 1 routine course of disease 15 years, two examples are the male, and the age all is 60 years old, and 1 example is the office worker, and 1 example is the retired worker; Blood stasis disease 1 example, pathogenic bacteria journey more than 30 year, 61 years old age.Above-mentioned case all had the gastric abscess history of repeated attack originally, and recurrent number obviously reduces after taking medicine, and pain degree also alleviates to some extent, controlling symptoms rapidly when taking medicine, but still have outbreak repeatedly.103 examples are observed in the cases, have during taking medicine the normal threshold of feeling such as xerostomia, do not observe untoward reaction.Wherein 61 years old male office worker of 1 example took 25 days continuously, and total amount reaches 150, did not find that also the patient has unusual discomfort.
Claims (3)
1. YUNWEINING capsule that is used for the treatment of gastropathy is characterized in that: it is by the Folium daturae that steams and fry the Rhizoma Seu Herba Bergeniae of processing and form Folium daturae by weight ratio: Rhizoma Seu Herba Bergeniae=1: 1.
2. the preparation technology of YUNWEINING capsule as claimed in claim 1 is characterized in that:
A, Folium daturae choose clean, avoid washing, are placed in the rice steamer; Earlier water in the end pot is heated to boiling, the rice steamer of putting the Folium daturae of packing into thereon continues to reduce to 90 ℃ after Zeng Ding emits steam and steamed 30 minutes being heated to more than 95 ℃, opens Zeng Gai rapidly and removes, take out Folium daturae, 40～60 ℃ of oven dry, fine ground powder is crossed 100 mesh sieves, and is standby;
B, Rhizoma Seu Herba Bergeniae, choose clean, be cut into the segment of 1 centimeter length, by weight ratio Rhizoma Seu Herba Bergeniae: Endoconcha Sepiae powder=1: 0.3 ratio, drop in the Endoconcha Sepiae powder that is heating, stir constantly, Rhizoma Seu Herba Bergeniae is fried to yellow skin but when not burnt, pulled out with skimming ladle, cool, sieve removes the Endoconcha Sepiae powder, Rhizoma Seu Herba Bergeniae is ground into fine powder cross 100 mesh sieves, and is standby;
C, will steam and fry the Folium daturae powder and the Rhizoma Seu Herba Bergeniae powder of processing, even by 1: 1 mixed, cross 100 mesh sieves, capsule is made in filling.
3. the preparation technology of YUNWEINING capsule as claimed in claim 2 is characterized in that: also mixed powder granulation filling can be become capsule.
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| CNA2003101108299A CN1539492A (en) | 2003-10-27 | 2003-10-27 | Medication for treating astriv disease, gastric ulcer and preparation technique |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111789902A (en) * | 2020-09-02 | 2020-10-20 | 朱明浩 | Application of content in Yunweining capsule in preparing anti-helicobacter pylori medicine |
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2003
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111789902A (en) * | 2020-09-02 | 2020-10-20 | 朱明浩 | Application of content in Yunweining capsule in preparing anti-helicobacter pylori medicine |
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