CN1537625A - Traditional Chinese medicine tablet prepn. method - Google Patents
Traditional Chinese medicine tablet prepn. method Download PDFInfo
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- CN1537625A CN1537625A CNA2003101078626A CN200310107862A CN1537625A CN 1537625 A CN1537625 A CN 1537625A CN A2003101078626 A CNA2003101078626 A CN A2003101078626A CN 200310107862 A CN200310107862 A CN 200310107862A CN 1537625 A CN1537625 A CN 1537625A
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- borneolum syntheticum
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Abstract
A Chinese medicine 'Zhenhuang tablet' is prepared from 7 Chinese-medicinal materials through pulverizing notoginseng, mixing with pig gall, drying, grinding to obtain fine powder, dissolving borneol in mint oil to obtain solution, grinding pearl, grinding bezoar, extracting from scutellaria root in alcohol to obtain liquid extract, mixing it with all powder, granulating, spraying said solution, tabletting and coating.
Description
Technical field
That the present invention relates to is the preparation technology of Chinese medicine preparation, refers in particular to the preparation method of the precious pornographic movie of a kind of Chinese medicine preparation that is formed by Margarita, Calculus Bovis, Radix Notoginseng, Radix Scutellariae, Borneolum Syntheticum, Oleum menthae, Fel Sus domestica compatibility.
Background technology
Calculus Bovis heat-clearing and toxic substances removing among the we, waking up the patient from unconsciousness by dissipating phlegm clears away heart-fire, modern pharmacology confirms that it contains compositions such as cholic acid and deoxycholic acid, can reduce central nervous system's excitement, thereby produce calm, analgesic activity, to endogenous fire formation, diseases such as the laryngopharynx swelling and pain due to wind heat is disturbed outward, aphtha of the mouth and tongue, carbuncle furunculosis have the obvious treatment effect; The hemostasis of Radix Notoginseng energy, dissipating blood stasis, analgesic therapy are share with Calculus Bovis, are played heat-clearing and toxic substances removing altogether, the effect of pain in the detumescence; Margarita energy removing toxic substances and promoting granulation, diseases such as erosion that throat, dispute are swollen and ache have the healing of promotion effect; Baicaligenin that Radix Scutellariae is contained and baicaligenin and baicalin all can resist anaphylaxis edema and inflammation, resist the release of anaphylaxis medium, demonstrate the broad-spectrum antibacterial and anti-inflammation functions; Borneolum Syntheticum has strongly fragrant, clearing away heat to alleviate pain, the anticorrosion merit of loosing of having one's ideas straightened out, can be used for carbuncle skin ulcer furuncle, sore throat, pharyngalgia, aphtha, gingival swelling and pain etc. multiple burning hot due to disease; The heat clearing away of Fel Sus domestica antiperspirant, moisturize, detoxifcation, Borneolum Syntheticum and Fel Sus domestica also have bacteriostasis, to swelling and ache, the removing of pyretic toxicity has facilitation; Oleum menthae energy dispelling wind heat, the sharp head; both strengthened the effect of principal agent; can further eliminate the burning hot heresy of still leaving in the body again; select the prescription of Chinese medicine Margarita, Calculus Bovis, Radix Notoginseng, Radix Scutellariae extract, Borneolum Syntheticum, Oleum menthae, Fel Sus domestica seven flavor compatibilities for use; capsule (seeing " Chinese drug standard " the 8th the 109th page) is only arranged at present, and all medicines share and complement each other, and play heat-clearing and toxic substances removing altogether; the effect of reducing swelling and alleviating pain, but its preparation is to only there being a kind of dosage form of capsule at present.
Summary of the invention
One object of the present invention is to provide the preparation method of the precious pornographic movie of a kind of Chinese medicine preparation.
The present invention is implemented by following scheme.
Component and weight proportion that the present invention gets raw material are (by weight):
40 parts of Margaritas, 16 parts of Calculus Boviss, 32 parts of Radix Notoginseng, 20 parts of Radix Scutellariaes, 1 part of Borneolum Syntheticum, 2 parts of Oleum menthae, 20 parts of compatibilities of Fel Sus domestica antiperspirant form;
Preparation method and step are: above seven flavor medicine, remove Oleum menthae, and outside the Borneolum Syntheticum, Radix Notoginseng powder is broken into fine powder and Fel Sus domestica antiperspirant mixing, and drying is ground into fine powder; Margarita grinds to form impalpable powder, and the Calculus Bovis porphyrize is scooped up thing and above-mentioned each powder mixing with Radix Scutellariae, and with ethanol system soft material, with 16-20 mesh sieve system granule, drying, granulate is dissolved in Borneolum Syntheticum in the Oleum menthae, and spray adds, tabletting, and coating, polishing is promptly.
And the preparation soft material is can be for Radix Notoginseng powder and mixed fine powder of gallbladder antiperspirant and Calculus Bovis, and behind Margarita and the Radix Scutellariae extract mixing, usefulness is about 10% 70% ethanol system soft material of dry powder amount;
And tabletting can be earlier Borneolum Syntheticum to be dissolved in the Oleum menthae before tabletting, and spray is added in the granule, airtight 12-36 hour, add 0.5% magnesium stearate mixing, and compacting is in flakes;
Coating then can be earlier with zein bag protecting film, reuse hydroxypropyl methyl fiber end (HPMC) coating.
Preparation method of the present invention is determining through repeatedly experimentation is preferred various supplementary product kinds in the preparation process and addition on the basis of conventional pill preparation method, have reasonable mixture ratio, technology is simple, be easy to control, the characteristics of constant product quality, no hazard residue.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following each embodiment only is used to illustrate the present invention, but to not restriction of the present invention.
Embodiment one
Take by weighing Margarita 40g; Calculus Bovis 160g; Radix Notoginseng 320g, Radix Scutellariae extract 200g; Borneolum Syntheticum 10g; Fel Sus domestica 200g; Oleum menthae 20g is with above seven flavors; remove Oleum menthae; outside the Borneolum Syntheticum; Radix Notoginseng powder is broken into fine powder, with Fel Sus domestica mix homogeneously, drying; wear into fine powder; Margarita is ground or water flies into impalpable powder, and the Calculus Bovis porphyrize is made soft material with adding 20% ethanol behind Radix Scutellariae extract and the above-mentioned powder mixing again; with 16 mesh sieve system granules; drying, granulate is dissolved in Borneolum Syntheticum to spray after the Oleum menthae and is added in the sieve series granule; airtight 12 hours; add 0.5% magnesium stearate mixing, tabletting is earlier with zein bag layer protecting film; reuse hydroxypropyl methyl fiber end coating, polishing.
Embodiment two
Take by weighing Margarita 20g; Calculus Bovis 80g; Radix Notoginseng 160g, Radix Scutellariae extract 100g; Borneolum Syntheticum 5g; Fel Sus domestica 100g; Oleum menthae 10g is with above seven flavors; remove Oleum menthae; outside the Borneolum Syntheticum; Radix Notoginseng powder is broken into fine powder, with Fel Sus domestica mix homogeneously, drying; wear into fine powder; Margarita is ground or water flies into impalpable powder, and the Calculus Bovis porphyrize is made soft material with adding 40% ethanol behind Radix Scutellariae extract and the above-mentioned powder mixing again; with 18 mesh sieve system granules; drying, granulate is dissolved in Borneolum Syntheticum to spray after the Oleum menthae and is added in the sieve series granule; airtight 16 hours; add 0.5% magnesium stearate mixing, tabletting is earlier with zein bag layer protecting film; reuse hydroxypropyl methyl fiber end coating, polishing.
Embodiment three
Take by weighing Margarita 40g; Calculus Bovis 160g; Radix Notoginseng 320g, Radix Scutellariae extract 200g; Borneolum Syntheticum 10g; Fel Sus domestica 200g; Oleum menthae 20g is with above seven flavors; remove Oleum menthae; outside the Borneolum Syntheticum; Radix Notoginseng powder is broken into fine powder, with Fel Sus domestica mix homogeneously, drying; wear into fine powder; Margarita is ground or water flies into impalpable powder, and the Calculus Bovis porphyrize is made soft material with adding 50% ethanol behind Radix Scutellariae extract and the above-mentioned powder mixing again; with 18 mesh sieve system granules; drying, granulate is dissolved in Borneolum Syntheticum to spray after the Oleum menthae and is added in the sieve series granule; airtight 20 hours; add 0.5% magnesium stearate mixing, tabletting is earlier with zein bag layer protecting film; reuse hydroxypropyl methyl fiber end coating, polishing.
Embodiment four
Take by weighing Margarita 20g; Calculus Bovis 80g; Radix Notoginseng 160g, Radix Scutellariae extract 100g; Borneolum Syntheticum 5g Fel Sus domestica 100g; Oleum menthae 10g is with above seven flavors; remove Oleum menthae; outside the Borneolum Syntheticum; Radix Notoginseng powder is broken into fine powder, with Fel Sus domestica mix homogeneously, drying; wear into fine powder; Margarita is ground or water flies into impalpable powder, and the Calculus Bovis porphyrize is made soft material with adding 60% ethanol behind Radix Scutellariae extract and the above-mentioned powder mixing again; with 20 mesh sieve system granules; drying, granulate is dissolved in Borneolum Syntheticum to spray after the Oleum menthae and is added in the sieve series granule; airtight 24 hours; add 0.5% magnesium stearate mixing, tabletting is earlier with zein bag layer protecting film; reuse hydroxypropyl methyl fiber end coating, polishing.
Embodiment five
Take by weighing Margarita 40g; Calculus Bovis 160g; Radix Notoginseng 320g, Radix Scutellariae extract 200g; Borneolum Syntheticum 10g; Fel Sus domestica 200g; Oleum menthae 20g is with above seven flavors; remove Oleum menthae; outside the Borneolum Syntheticum; Radix Notoginseng powder is broken into fine powder, with Fel Sus domestica mix homogeneously, drying; wear into fine powder; Margarita is ground or water flies into impalpable powder, and the Calculus Bovis porphyrize is made soft material with adding 70% ethanol behind Radix Scutellariae extract and the above-mentioned powder mixing again; with 18 mesh sieve system granules; drying, granulate is dissolved in Borneolum Syntheticum to spray after the Oleum menthae and is added in the sieve series granule; airtight 36 hours; add 0.5% magnesium stearate mixing, tabletting is earlier with zein bag layer protecting film; reuse hydroxypropyl methyl fiber end coating, polishing.
Claims (4)
1; the precious pornographic movie of a kind of Chinese medicine preparation is by 40 parts of Margaritas; 16 parts of Calculus Boviss; 32 parts of Radix Notoginseng; 20 parts of Radix Scutellariae extracts; 1 part of Borneolum Syntheticum; 2 parts of Oleum menthae; 20 parts of compatibilities of Fel Sus domestica are prepared from; it is characterized in that preparation method is: with above seven flavors; remove Oleum menthae; outside the Borneolum Syntheticum; Radix Notoginseng powder is broken into fine powder; with the Fel Sus domestica mix homogeneously, drying is worn into fine powder; Margarita is ground or water flies into impalpable powder; the Calculus Bovis porphyrize is made soft material with adding ethanol behind Radix Scutellariae extract and the above-mentioned powder mixing again, uses the sieve series granule; dry; granulate, spray adds the solution after Borneolum Syntheticum dissolves in Oleum menthae, tabletting then; the bag film-coat, polishing.
2, the preparation method of the precious pornographic movie of Chinese medicine preparation as claimed in claim 1; it is characterized in that: described soft material preparation is with behind Radix Notoginseng powder and the mixed fine powder of Fel Sus domestica and Calculus Bovis, Margarita and the Radix Scutellariae extract mixing, and the ethanol blending of the 10%-70% of adding dry powder amount forms.
3, the preparation method of the precious pornographic movie of Chinese medicine preparation as claimed in claim 1 or 2 is characterized in that: in the said process Borneolum Syntheticum is dissolved in spray after the Oleum menthae and is added in the sieve series granule, airtight 12 hours-36 hours tablettings again wrap film-coat, polishing.
4, the preparation method of the precious pornographic movie of Chinese medicine preparation as claimed in claim 3 is characterized in that: coating is to wrap protecting film with zein earlier in the said process, reuse hydroxypropyl methyl fiber end coating.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2003101078626A CN1537625A (en) | 2003-10-08 | 2003-10-08 | Traditional Chinese medicine tablet prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2003101078626A CN1537625A (en) | 2003-10-08 | 2003-10-08 | Traditional Chinese medicine tablet prepn. method |
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| Publication Number | Publication Date |
|---|---|
| CN1537625A true CN1537625A (en) | 2004-10-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2003101078626A Pending CN1537625A (en) | 2003-10-08 | 2003-10-08 | Traditional Chinese medicine tablet prepn. method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101697998B (en) * | 2009-06-13 | 2012-01-11 | 浙江天一堂集团有限公司 | Zhenhuang tablet for treating sore throat and ulcer and sore furuncle and preparation method thereof |
| CN103301193A (en) * | 2013-06-29 | 2013-09-18 | 陆娜 | Drug for treating aphtha and preparation method thereof |
-
2003
- 2003-10-08 CN CNA2003101078626A patent/CN1537625A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101697998B (en) * | 2009-06-13 | 2012-01-11 | 浙江天一堂集团有限公司 | Zhenhuang tablet for treating sore throat and ulcer and sore furuncle and preparation method thereof |
| CN103301193A (en) * | 2013-06-29 | 2013-09-18 | 陆娜 | Drug for treating aphtha and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |