CN1522719A - Pharmaceutical composition for treating rheumatism, rheumatoid arthritis and limb pains, and its preparation method - Google Patents
Pharmaceutical composition for treating rheumatism, rheumatoid arthritis and limb pains, and its preparation method Download PDFInfo
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- CN1522719A CN1522719A CNA031048218A CN03104821A CN1522719A CN 1522719 A CN1522719 A CN 1522719A CN A031048218 A CNA031048218 A CN A031048218A CN 03104821 A CN03104821 A CN 03104821A CN 1522719 A CN1522719 A CN 1522719A
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Abstract
The present invention discloses a medicine composition in treating the prolapse of lumbar intervertebral disk, rheumatic arthritis, rheumatoid arthritis, pain of limbs and soft tissue injury, etc. Said composition is made up of 35 Chinese medicinal materials of notopterygium root, pubescent angelica root, clematis root, large-leaf gentian root, acanthopanax bark and others. Said invented medicine composition can be made into the traditional Chinese adhesive plaster through a certain preparation process.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of rheumatism, rheumatoid arthritis and limbs pain and preparation method thereof.
Background technology
Plaster is an important component part in motherland's medicine and pharmacology, and is particularly important to the acute and chronic trauma treatment of arthromyodynia, hyperosteogeny, soft tissue especially, some disease even one of the requisite Therapeutic Method of saying so.The plaster treatment curative effect of disease is definite, has avoided the oral easy stimulation stomach of Chinese medicine and western medicine, and injection easily causes the pain drawback, and easy to use, easy to carry, just payes attention to and widespread usage for the working people since ancient times.Market prospect is boundless, but traditional plaster at prescription, be manufactured with a lot of drawbacks, influence the curative effect that plaster is cured the disease.The plaster substrate innovation, black plaster is one of ancient preparation of motherland medicine, generally still continues to use the traditional method manufacturing so far, temper uniform temperature as Oleum sesami, Oleum Gossypii semen after, be lowered to Plumbum preparatium, this substrate is used inconvenience, needs the soft back of baking to paste usefulness, and color is pitch black and easily pollute clothes, easily slide, washing inconvenience, and operation sequence is numerous and diverse, is difficult to grasp.Resting period is easily aging becoming fragile more than 1 year.Traditional spice extracts to adopt puts into pot to vegetable oil, and spice is put into fried getting.But vegetable oil is nonpolar solvent, to alkaloid, salt, some glycoside isopolarity composition is insoluble, though can dissolve compositions such as free alkaloid, flavonoid glycosides, anthraquinone glycoside, but at high temperature destroyed mostly, resin, face cream and volatile ingredient are met easy separated and dissolved of high temperature and volatilization.Moreover behind the conventional pastes plaster clothes, drug transdermal sucks slowly, also leaves over many ingredients and is not absorbed, and greatly reduces therapeutical effect, and the conventional pastes coating mostly is to become one with paper mounting with cloth, or with animal skin (as dog skin), makes plaster, easily flow during subsides, easy pollution clothes, viscosity is relatively poor.
Technology contents
The object of the present invention is to provide a kind of pharmaceutical composition for the treatment of rheumatism, rheumatoid arthritis and limbs pain and preparation method thereof.
The present invention is achieved through the following technical solutions: choose crude drug
Category-A: Rhizoma Et Radix Notopterygii 20-100 weight portion Radix Angelicae Pubescentis 20-100 weight portion
Radix Clematidis 50-150 weight portion Radix Gentianae Macrophyllae 20-100 weight portion
Cortex Acanthopancis 40-120 weight portion Herba Taxilli 20-100 weight portion
Radix Saposhnikoviae 20-100 weight portion Cortex Cinnamomi 20-100 weight portion
Rhizoma Zingiberis 50-150 weight portion Fructus Capsici 50-150 weight portion
Rhizoma Corydalis 20-100 weight portion Semen Persicae 10-60 weight portion
Radix Angelicae Sinensis 10-60 weight portion Rhizoma Drynariae 20-100 weight portion
Radix Morindae Officinalis 20-100 weight portion Flos Daturae 20-100 weight portion
Rhizoma Arisaematis 20-100 weight portion Semen Sinapis Albae 5-20 weight portion
Category-B: Radix Aconiti 20-100 weight portion Radix Aconiti Kusnezoffii 20-100 weight portion
Olibanum 10-60 weight portion Myrrha 10-60 weight portion
Sanguis Draxonis 10-60 weight portion Agkistrodon 10-60 weight portion
Flos Caryophylli 10-60 weight portion stir-baked SQUAMA MANITIS 10-60 weight portion
Scolopendra 10-60 weight portion Scorpio 10-60 weight portion
Pheretima 10-60 weight portion Semen Strychni 20-120 weight portion
Herba Asari 10-60 weight portion Radix Aucklandiae 10-40 weight portion
C class: Venenum Bufonis 5-40 weight portion Camphora 5-40 weight portion
Borneolum Syntheticum 10-80 weight portion
Optimum ratio of the present invention is:
Category-A: Rhizoma Et Radix Notopterygii 50 weight portion Radix Angelicae Pubescentiss 50 weight portions
Radix Clematidis 100 weight portion Radix Gentianae Macrophyllae 50 weight portions
Cortex Acanthopancis 80 weight portion Herba Taxillis 50 weight portions
Radix Saposhnikoviae 50 weight portion Cortex Cinnamomis 50 weight portions
Rhizoma Zingiberis 100 weight portion Fructus Capsicis 100 weight portions
Rhizoma Corydalis 50 weight portion Semen Persicaes 30 weight portions
Radix Angelicae Sinensis 30 weight portion Rhizoma Drynariae 50 weight portions
Radix Morindae Officinalis 50 weight portion Flos Daturaes 50 weight portions
Rhizoma Arisaematis 50 weight portions
Semen Sinapis Albae 10 weight portions
Category-B: Radix Aconiti 50 weight portion Radix Aconiti Kusnezoffii 50 weight portions
Olibanum 50 weight portion Myrrha 30 weight portions
Sanguis Draxonis 30 weight portion Agkistrodons 30 weight portions
Flos Caryophylli 30 weight portion stir-baked SQUAMA MANITISs 30 weight portions
Scolopendra 30 weight portion Scorpio 30 weight portions
Pheretima 30 weight portion Semen Strychni 60 weight portions
The Herba Asari 30 weight portion Radix Aucklandiae 20 weight portions
C class: Venenum Bufonis 20 weight portion Camphoras 20 weight portion Borneolum Syntheticums 40 weight portions
Preparation of drug combination method of the present invention is made as follows:
1, the preparation of new black plaster substrate:
Method for making: get polrvinyl chloride 100-200 weight portion and put in the pot, add phthalic acid dibutyl ester 500-800 weight portion, stir, on straight fire, heat, constantly stir, the heating kettle temperature reaches 80-120 ℃, and paste is white in color, be warming up to 120-150 ℃ more gradually, and often stir, to being transparent thickness body, gradation adds the Colophonium powder 80-150 weight portion of 40 order fine powders, the limit edged stirs, should be yellow homogeneous transparent thickness body after adding, maintain the temperature at below 100-140 ℃, gradation adds oxide powder and zinc 100-1500 weight portion, fully stir, the 100-140 weight portion that camphorates again stirs evenly promptly;
2, category-A drug extract preparation:
With category-A medical material or decoction pieces in the above-mentioned prescription, the water logging of heating bubble is after 0.3-1 hour, heating decocts 2 times, boiled the follow-up 0.3-1 of frying in shallow oil hour at every turn, leach medicinal liquid, decoct medicinal liquid with twice and leave standstill more than 20-40 hour, the leaching supernatant concentration is to extractum shape (extension flag), or with gravity Baume table survey relative density 1.1-1.20 (70-80 ℃), standby;
3, category-B drug powder preparation:
The category-B medical material is mixed, be ground into fine powder, be placed in the hermetic container standby;
4, C class medicine should be pulverized separately, the porphyrize powder, and it is standby to put into another container separately;
5, get plaster substrate, with the slow fire fusing, in the time of about 50-90 to be cooled ℃, under constantly stirring, slowly add the category-A drug extract, after stirring, continuation is heated with slow fire, to remove aqueous vapor, is cooled to about 50-90 ℃ from fire again, add category-B medicated powder, put into laurocapram 10-60 weight portion again, stir, can spread out and be coated with.
6, the stand is coated with:
The making of plaster skin: get a block length 10cm earlier, one of the calico that wide 8cm starched, the stand is coated with plaster 20 grams, divide evenly, be sprinkled into C class medicated powder, cover plastic sheeting, after cooling, calico around unnecessary is cut off, putting a block length 14cm, on the wide 12cm rectangle rubber plaster, and then with one with the same big thicker plastic paper of rubber plaster, above topped.Every subsides 20 grams.Time spent is thrown off plaster upper two layers plastic paper, wipes clean skin, is affixed on the affected part or by place, relevant acupuncture point, changes once in 3-5 days.
Pharmaceutical composition of the present invention has expelling wind and removing dampness, dispersing cold for relieving pain, blood circulation promoting and blood stasis dispelling, the effect of dredging the meridian is to treatment anemofrigid-damp arthralgia, extremity, joint, lumbar and back pain numbness, hyperosteogeny, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, rheumatism, rheumatoid arthritis and soft tissue injury etc. have remarkable result.
Pharmaceutical composition of the present invention is to 500 routine patients statistics, the arthromyodynia for wind and cold due to wet, and hyperosteogeny, and various soft tissues are anxious, and to damage cure rate slowly be 49.4%, and obvious effective rate is 33%, total effective rate is 98%.
Medicine composite for curing patient case of the present invention is as follows:
Zhao * *, woman, 54 years old.Go to a doctor January 15 calendar year 2001.Right shoulder arthralgia, limitation of activity 4 months surplus, be diagnosed as scapulohumeral periarthritis.Recently the first quarter moon state of an illness increases the weight of, and can not comb one's hair the difficulty of wearing the clothes.Right shoulder is sent out cold.Look into, take on front and rear portions, the outside when tenderness crawl abduction is all arranged shoulder towering.Shoulder joint abduction 60 degree.Local muscle does not have redness, no amyotrophy, dimly pale tongue, stringy and tense pulse.Behind the shoulder joint massage, paste with the present invention's " wind-evil dispelling and cold-evil expelling invigorate blood circulation cream " 2 at the front-back of suffering from shoulder and to paste, further consultation after 7 days, shoulder pain obviously alleviates, and the joint motion amplitude increases, and exchanges cards containing all personal details and become sworn brothers 2 to paste again.Phone is followed up a case by regular visits to the disappearance of patient's pain after 20 days, and functional activity is normal.
Open * *, man 54 years old, the railway station porter, go to a doctor March 13 calendar year 2001, and neck portion distending pain discomfort with surplus right side shoulder, the back pain existing 3 year, and with numb nearly 10 days of left upper extremity, is brought out because of catching cold, and pain increases the weight of.Look into: cervical vertebra X line is taken the photograph sheet physiology curvature and is become straight, C4-7 vertebral body front and rear edge hyperosteogeny.The C6-7 narrowing of intervertebral space.Pale tongue with white fur, stringy and tense pulse.Examine and be hyperosteogeny of cervical vertebra.Through at C4-7 vertebral body place, the invention " wind-evil dispelling and cold-evil expelling invigorate blood circulation cream " 3 that loses money in a business of shoulder back, Quchi acupoint place is pasted, further consultation in 10 days, and all diseases alleviate half, continuously paste 3 subsides, and pain disappears substantially behind the first quarter moon, and the cervical region activity is freely.Follow up a case by regular visits to half a year and do not have recurrence.
Yellow * *, man 27 years old, the peasant, go to a doctor August 11 calendar year 2001, and the patient goes to a doctor the previous day, and behind the lift to move weight, waist has an intense pain, and the anterior flexion and rear stretching of waist, rotary moveable are all limited, can only put down for sleeping in.Look into: the X line is taken the photograph sheet and is shown that lumbar spine is lateral bending left, and the L3-4 interbody space increases, and tongue fur is light white, stringy and tense pulse.Examine and be acute lumbar muscle sprain.Waist sticks the present invention's " wind-evil dispelling and cold-evil expelling invigorate blood circulation cream " 2 and pastes, and pain symptom takes a turn for the better after 7 days, continues reuse 2 and pastes, and behind the first quarter moon, all diseases disappear, and the waist functional activity is normal.
Embodiment
Category-A: Rhizoma Et Radix Notopterygii 50g Radix Angelicae Pubescentis 50g Radix Clematidis 100g
Radix Gentianae Macrophyllae 50g Cortex Acanthopancis 80g Herba Taxilli 50g
Radix Saposhnikoviae 50g Cortex Cinnamomi 50g Rhizoma Zingiberis 100g
Fructus Capsici 100g Rhizoma Corydalis 50g Semen Persicae 30g
Radix Angelicae Sinensis 30g Rhizoma Drynariae 50g halberd sky 50g
Flos Daturae 50g Rhizoma Arisaematis 50g Semen Sinapis Albae 10g
Category-B: Radix Aconiti 50g Radix Aconiti Kusnezoffii 50g Olibanum 50g
Myrrha 30g Sanguis Draxonis 30g Agkistrodon 30g
Flos Caryophylli 30g stir-baked SQUAMA MANITIS 30g Scolopendra 30g
Scorpio 30g Pheretima 30g Semen Strychni 60g
Herba Asari 30g Radix Aucklandiae 20g
C class: Venenum Bufonis 20g Camphora 20g Borneolum Syntheticum 40g
The preparation of new black plaster substrate: get polrvinyl chloride powder 140g and add phthalic acid dibutyl ester 670g, stir, on straight fire, heat, constantly stir, the heating kettle temperature reaches about 100 ℃, the paste that is white in color is warming up to 140 ℃ more gradually, and often stirs, to being transparent thickness body, gradation adds the Colophonium powder 120g of 40 order fine powders, and the limit edged stirs, and should be yellow homogeneous transparent thickness body after adding, maintain the temperature at below 120 ℃, gradation adds oxide powder and zinc 1200g, fully stirs, and the 120g that camphorates again stirs evenly promptly;
Category-A drug extract preparation: with category-A medical material or decoction pieces in the above-mentioned prescription, the water logging of heating bubble is after 0.8 hour, heating decocts 2 times, follow-up the frying in shallow oil 0.5 hour of at every turn boiling, leach medicinal liquid, decoct medicinal liquid with twice and leave standstill more than 24 hours, the leaching supernatant concentration is to extractum shape (extension flag), or with gravity Baume table survey relative density 1.1-1.20 (70-80 ℃), standby;
Category-B drug powder preparation: the category-B medical material is mixed, be ground into fine powder, be placed in the hermetic container standby;
C class medicine should be pulverized separately, the porphyrize powder, and it is standby to put into another container separately;
Get plaster substrate 4130g, with the slow fire fusing, in the time of about 70 ℃ to be cooled, under constantly stirring, slowly add the category-A drug extract, after stirring, continuation is heated with slow fire, to remove aqueous vapor, is cooled to about 70 ℃ from fire again, add category-B medicated powder, put into laurocapram 30ml again, stir, can spread out and be coated with;
The making of plaster skin: get a block length 10cm earlier, one of the calico that wide 8cm starched, stand are coated with plaster 20 grams, divide evenly, be sprinkled into C class medicated powder, cover plastic sheeting, after cooling, the calico around unnecessary is cut off, putting on the wide 12cm rectangle of the block length 14cm rubber plaster, and then with one with the same big thicker plastic paper of rubber plaster, topped above.Every subsides 20 grams.Time spent is thrown off plaster upper two layers plastic paper, wipes clean skin, is affixed on the affected part or by place, relevant acupuncture point, changes once in 3-5 days.
Claims (4)
1, a kind of pharmaceutical composition for the treatment of rheumatism, rheumatoid arthritis and limbs pain is characterized in that said composition is to be made by following crude drug:
Category-A: Rhizoma Et Radix Notopterygii 20-100 weight portion Radix Angelicae Pubescentis 20-100 weight portion
Radix Clematidis 50-150 weight portion Radix Gentianae Macrophyllae 20-100 weight portion
Cortex Acanthopancis 40-120 weight portion Herba Taxilli 20-100 weight portion
Radix Saposhnikoviae 20-100 weight portion Cortex Cinnamomi 20-100 weight portion
Rhizoma Zingiberis 50-150 weight portion Fructus Capsici 50-150 weight portion
Rhizoma Corydalis 20-100 weight portion Semen Persicae 10-60 weight portion
Radix Angelicae Sinensis 10-60 weight portion Rhizoma Drynariae 20-100 weight portion
Radix Morindae Officinalis 20-100 weight portion Flos Daturae 20-100 weight portion
Rhizoma Arisaematis 20-100 weight portion Semen Sinapis Albae 5-20 weight portion
Category-B: Radix Aconiti 20-100 weight portion Radix Aconiti Kusnezoffii 20-100 weight portion
Olibanum 10-60 weight portion Myrrha 10-60 weight portion
Sanguis Draxonis 10-60 weight portion Agkistrodon 10-60 weight portion
Flos Caryophylli 10-60 weight portion stir-baked SQUAMA MANITIS 10-60 weight portion
Scolopendra 10-60 weight portion Scorpio 10-60 weight portion
Pheretima 10-60 weight portion Semen Strychni 20-120 weight portion
Herba Asari 10-60 weight portion Radix Aucklandiae 10-40 weight portion
C class: Venenum Bufonis 5-40 weight portion Camphora 5-40 weight portion
Borneolum Syntheticum 10-80 weight portion.
2, pharmaceutical composition according to claim 1 is characterized in that said composition is to be made by following crude drug:
Category-A: Rhizoma Et Radix Notopterygii 50 weight portion Radix Angelicae Pubescentiss 50 weight portion Radix Clematidis 100 weight portions
Radix Gentianae Macrophyllae 50 weight portion Cortex Acanthopanciss 80 weight portion Herba Taxillis 50 weight portions
Radix Saposhnikoviae 50 weight portion Cortex Cinnamomis 50 weight portion Rhizoma Zingiberiss 100 weight portions
Fructus Capsici 100 weight portion Rhizoma Corydalis 50 weight portion Semen Persicaes 30 weight portions
Radix Angelicae Sinensis 30 weight portion Rhizoma Drynariae 50 weight portion Radix Morindae Officinaliss 50 weight portions
Flos Daturae 50 weight portion Rhizoma Arisaematis 50 weight portion Semen Sinapis Albaes 10 weight portions
Category-B: Radix Aconiti 50 weight portion Radix Aconiti Kusnezoffii 50 weight portion Olibanum 50 weight portions
Myrrha 30 weight portion Sanguis Draxonis 30 weight portion Agkistrodons 30 weight portions
Flos Caryophylli 30 weight portion stir-baked SQUAMA MANITISs 30 weight portion Scolopendras 30 weight portions
Scorpio 30 weight portion Pheretimas 30 weight portion Semen Strychni 60 weight portions
The Herba Asari 30 weight portion Radix Aucklandiae 20 weight portions
C class: Venenum Bufonis 20 weight portion Camphoras 20 weight portion Borneolum Syntheticums 40 weight portions.
3, a kind of preparation of drug combination method for the treatment of rheumatism, rheumatoid arthritis and limbs pain is characterized in that this preparation method is to make as follows:
1) preparation of new black plaster substrate:
Method for making: get polrvinyl chloride 100-200 weight portion and put in the pot, add phthalic acid dibutyl ester 500-800 weight portion, stir, on straight fire, heat, constantly stir, the heating kettle temperature reaches 80-120 ℃, and paste is white in color, be warming up to 120-150 ℃ more gradually, and often stir, to being transparent thickness body, gradation adds the Colophonium powder 80-150 weight portion of 40 order fine powders, the limit edged stirs, should be yellow homogeneous transparent thickness body after adding, maintain the temperature at below 100-140 ℃, gradation adds oxide powder and zinc 100-1500 weight portion, fully stir, the 100-140 weight portion that camphorates again stirs evenly promptly;
2) category-A drug extract preparation:
With category-A medical material or decoction pieces in the above-mentioned prescription, the water logging of heating bubble is after 0.3-1 hour, heating decocts 2 times, boiled the follow-up 0.3-1 of frying in shallow oil hour at every turn, leach medicinal liquid, decoct medicinal liquid with twice and leave standstill more than 20-40 hour, the leaching supernatant concentration is to hanging flag extractum shape, or about 70-80 ℃, survey relative density 1.1-1.20 with the gravity Baume table, standby;
3) category-B drug powder preparation:
The category-B medical material is mixed, be ground into fine powder, be placed in the hermetic container standby;
4) C class medicine should be pulverized separately, the porphyrize powder, and it is standby to put into another container separately;
5) get plaster substrate, with the slow fire fusing, in the time of about 50-90 to be cooled ℃, under constantly stirring, slowly add the category-A drug extract, after stirring, continuation is heated with slow fire, to remove aqueous vapor, is cooled to about 50-90 ℃ from fire again, add category-B medicated powder, put into laurocapram 10-60 weight portion again, stir, can spread out and be coated with;
6) stand is coated with:
The making of plaster skin: get a block length 10cm earlier, one of the calico that wide 8cm starched, the stand is coated with plaster 20 grams, divide evenly, be sprinkled into C class medicated powder, cover plastic sheeting, after cooling, calico around unnecessary is cut off, putting a block length 14cm, on the wide 12cm rectangle rubber plaster, and then with one with the same big thicker plastic paper of rubber plaster, above topped.
4, preparation of drug combination method according to claim 3 is characterized in that this preparation method is:
1) preparation of new black plaster substrate: get polrvinyl chloride powder 140g and add phthalic acid dibutyl ester 670g, stir, on straight fire, heat, constantly stir, the heating kettle temperature reaches about 100 ℃, the paste that is white in color is warming up to 140 ℃ more gradually, and often stirs, to being transparent thickness body, gradation adds the Colophonium powder 120g of 40 order fine powders, and the limit edged stirs, and should be yellow homogeneous transparent thickness body after adding, maintain the temperature at below 120 ℃, gradation adds oxide powder and zinc 1200g, fully stirs, and the 120g that camphorates again stirs evenly promptly;
2) category-A drug extract preparation: with category-A medical material in the above-mentioned prescription, the water logging of heating bubble is after 0.8 hour, heating decocts 2 times, follow-up the frying in shallow oil 0.5 hour of at every turn boiling, leach medicinal liquid, decoct medicinal liquid with twice and leave standstill more than 24 hours, the leaching supernatant concentration is to hanging flag extractum shape, or about 70-80 ℃, survey relative density 1.1-1.20 with the gravity Baume table, standby;
3) category-B drug powder preparation: the category-B medical material is mixed, be ground into fine powder, be placed in the hermetic container standby;
4) C class medicine should be pulverized separately, the porphyrize powder, and it is standby to put into another container separately;
5) get plaster substrate 4130g, with the slow fire fusing, in the time of about 70 ℃ to be cooled, under constantly stirring, slowly add the category-A drug extract, after stirring, continuation is heated with slow fire, to remove aqueous vapor, is cooled to about 70 ℃ from fire again, add category-B medicated powder, put into laurocapram 30ml again, stir, can spread out and be coated with;
6) making of plaster skin: get a block length 10cm earlier, one of the calico that wide 8cm starched, stand are coated with plaster 20 grams, divide evenly, be sprinkled into C class medicated powder, cover plastic sheeting, after cooling, the calico around unnecessary is cut off, putting on the wide 12cm rectangle of the block length 14cm rubber plaster, and then with one with the same big thicker plastic paper of rubber plaster, topped above.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031048218A CN1244374C (en) | 2003-02-20 | 2003-02-20 | Pharmaceutical composition for treating rheumatism, rheumatoid arthritis and limb pains, and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031048218A CN1244374C (en) | 2003-02-20 | 2003-02-20 | Pharmaceutical composition for treating rheumatism, rheumatoid arthritis and limb pains, and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1522719A true CN1522719A (en) | 2004-08-25 |
| CN1244374C CN1244374C (en) | 2006-03-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031048218A Expired - Fee Related CN1244374C (en) | 2003-02-20 | 2003-02-20 | Pharmaceutical composition for treating rheumatism, rheumatoid arthritis and limb pains, and its preparation method |
Country Status (1)
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| CN (1) | CN1244374C (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100350935C (en) * | 2005-04-22 | 2007-11-28 | 缪立文 | Medicine composition for treating rheumatoid arthritis and rheumatism |
| CN100353996C (en) * | 2005-10-24 | 2007-12-12 | 广州中医药大学 | Medicine composition for treating soft tissue damage and osteoarthropathy and its prepn process |
| CN100364572C (en) * | 2005-10-30 | 2008-01-30 | 王伟筹 | Chinese medicine preparation for treating old wound |
| CN102416049A (en) * | 2011-12-06 | 2012-04-18 | 常西海 | Small square type rheumatoid swelling diminishing and pain eliminating plaster and preparation method thereof |
| CN102186489B (en) * | 2008-10-07 | 2013-10-02 | 特拉维夫大学拉玛特有限公司 | Use of cinnamon bark extract for treating amyloid-associated diseases |
| CN105287721A (en) * | 2015-08-11 | 2016-02-03 | 杭州市中医院 | Chinese herbal compound for treating arthritis, cataplasm preparation of Chinese herbal compound for treating arthritis and method for preparing cataplasm preparation |
| CN108310331A (en) * | 2018-05-08 | 2018-07-24 | 葛新军 | A kind of the external application medical ointment formula and preparation method and application of analgesic |
| CN109010561A (en) * | 2018-10-10 | 2018-12-18 | 孙斌 | A kind of plaster and preparation method thereof |
-
2003
- 2003-02-20 CN CNB031048218A patent/CN1244374C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100350935C (en) * | 2005-04-22 | 2007-11-28 | 缪立文 | Medicine composition for treating rheumatoid arthritis and rheumatism |
| CN100353996C (en) * | 2005-10-24 | 2007-12-12 | 广州中医药大学 | Medicine composition for treating soft tissue damage and osteoarthropathy and its prepn process |
| CN100364572C (en) * | 2005-10-30 | 2008-01-30 | 王伟筹 | Chinese medicine preparation for treating old wound |
| CN102186489B (en) * | 2008-10-07 | 2013-10-02 | 特拉维夫大学拉玛特有限公司 | Use of cinnamon bark extract for treating amyloid-associated diseases |
| CN102416049A (en) * | 2011-12-06 | 2012-04-18 | 常西海 | Small square type rheumatoid swelling diminishing and pain eliminating plaster and preparation method thereof |
| CN102416049B (en) * | 2011-12-06 | 2014-07-09 | 常西海 | Small square type rheumatoid swelling diminishing and pain eliminating plaster and preparation method thereof |
| CN105287721A (en) * | 2015-08-11 | 2016-02-03 | 杭州市中医院 | Chinese herbal compound for treating arthritis, cataplasm preparation of Chinese herbal compound for treating arthritis and method for preparing cataplasm preparation |
| CN108310331A (en) * | 2018-05-08 | 2018-07-24 | 葛新军 | A kind of the external application medical ointment formula and preparation method and application of analgesic |
| CN109010561A (en) * | 2018-10-10 | 2018-12-18 | 孙斌 | A kind of plaster and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1244374C (en) | 2006-03-08 |
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