CN1520857A - Diabetes treating bitter gourd traditional Chinese medicine - Google Patents
Diabetes treating bitter gourd traditional Chinese medicine Download PDFInfo
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- CN1520857A CN1520857A CNA031117678A CN03111767A CN1520857A CN 1520857 A CN1520857 A CN 1520857A CN A031117678 A CNA031117678 A CN A031117678A CN 03111767 A CN03111767 A CN 03111767A CN 1520857 A CN1520857 A CN 1520857A
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- chinese medicine
- fructus momordicae
- momordicae charantiae
- treatment
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Abstract
The diabetes treating Chinese medicine balsam pear preparation consists of balsam pear extractive as active component in 1-80 portions and matrix in 20-80 portions. The Chinese medicine is prepared through crushing balsam pear extractive, mixing with matrix and processing into the required form tablet or dripping pill. The matrix for the tablet includes mannitol, chitinamine and sweeter; and that for pilling pill is polyglycol 4000-6000, sodium stearate, glycerine-glutin, urea-citric acid or glyceryl stearate. The Chinese medicine may be well absorbed to treat various diabetes effectively.
Description
Affiliated technical field
The present invention relates to a kind of medicine for the treatment of diabetes, particularly a kind of is the Chinese medicine preparation of main effective ingredient by Fructus Momordicae charantiae extract.
Technical background
Fructus Momordicae charantiae extract is the active drug of treatment diabetes.The health product of being made by Fructus Momordicae charantiae extract are arranged at present, by the Chinese medicine preparation of Fructus Momordicae charantiae extract manufacturing yet there are no in report.
Summary of the invention
At the shortcoming that above-mentioned prior art exists, the object of the present invention is to provide a kind of absorption better, the onset of treatment diabetes is the Fructus Momordicae charantiae Chinese medicine preparation faster.
Technical scheme of the present invention is based on understanding and the Therapeutic Principle of Chinese medicine to onset diabetes mechanism, the invention of tracking modern pharmacological research, the Fructus Momordicae charantiae extract that filters out from plant class Chinese herbal medicine the treatment diabetes is equipped with substrate, buccal tablet and two kinds of Chinese medicine preparation of drop pill of making, the dosage form of this medicine is for being beneficial to absorption especially, and directly absorbs through the oral cavity without stomach.The pharmacological action of Fructus Momordicae charantiae extract is as follows: promote the secretion of serum insulin 1.; 2. the secretion of glucagon suppression; 3. repairing islet cells; 4. blood fat reducing.
The Fructus Momordicae charantiae Chinese medicine preparation of this kind treatment diabetes is made up of medicine and substrate, it is characterized in that (weight portion):
Medicine is Fructus Momordicae charantiae extract 1-80 part;
Substrate 20-80 part;
By the prescription thing of getting it filled, after the pulverizing,, be processed into dosage form with the substrate mixing.Two kinds of dosage forms of buccal tablet and drop pill are arranged.
When described dosage form was drop pill, Fructus Momordicae charantiae extract was preferably 1-40 part; Substrate is Macrogol 4000-6000 or sodium stearate or glycerol-gelatin or carbamide-poly-rafter acid or glyceryl stearate.The preparation method of its drop pill is: after getting Fructus Momordicae charantiae extract and be crushed to 80-100 order granularity by prescription, with the substrate mixing, be heated to 80-100 ℃ of said medicine and enter molten condition, stir, adopting craft or machinery that spice is splashed in 15 ℃ of its liquid paraffins through the rustless steel nib under the 60-80 ℃ of keeping warm mode, cooling forming at room temperature, the demoulding promptly after the shaping.The heavy 1-30mg of drop pill.Day obeys 3 times, each 10.
When described dosage form was tablet, Fructus Momordicae charantiae extract was 1-80 part; Substrate is mannitol: chitosan: sweeting agent corresponds to 1: 0.25～and 0.125: 0.025～0.062.The preparation method of its tablet is: after getting Fructus Momordicae charantiae extract and be crushed to 80-100 order granularity by prescription, with substrate mixing, tabletting.The heavy 800mg of sheet, day is sucked clothes 3 times, each 1-2 sheet.
This medicine has better curative effect to the treatment diabetes.This medicine dropped into clinical trial in 2000, according to 618 routine patients' case history statistics, total effective rate reaches 80%, and this medicine of the common reflection of patient has easy absorption, instant effect, characteristics evident in efficacy.Now show with following case:
Liu XX, the woman, 48 years old, bran urine was sick, and fasting glucose 16mmol/L took this medicine after 1 month, and fasting glucose is reduced to 6.1mmol/L, and the back of taking medicine does not have other discomforts.
Song XX, the man, 50 years old, bran urine was sick, and fasting glucose 14mmol/L took this medicine after 1 month, and cavity blood bran is reduced to 5.6mmol/L, and the back of taking medicine does not have other discomforts.
High XX, the man, 46 years old, bran urine was sick, and fasting glucose 13mmol/L took this medicine after 1 month, and fasting glucose is reduced to 5.1mmol/L, and the back of taking medicine does not have other discomforts.
Specific embodiment:
1, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 40 parts of medicine Fructus Momordicae charantiae extracts; 80 parts of substrate.Substrate is Macrogol 4000-6000
Or sodium stearate or glycerol-gelatin or carbamide-poly-rafter acid or glyceryl stearate.
Compound method: after getting Fructus Momordicae charantiae extract and be crushed to 80-100 order granularity by prescription, with the substrate mixing, be heated to 80-100 ℃ of said medicine and enter molten condition, stir, adopting craft or machinery that spice is splashed in 15 ℃ of its liquid paraffins through the rustless steel nib under the 60-80 ℃ of keeping warm mode, cooling forming at room temperature, the demoulding promptly gets drop pill after the shaping.
2, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 30 parts of medicine Fructus Momordicae charantiae extracts; 60 parts of substrate.All the other are the same.
3, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 10 parts of medicine Fructus Momordicae charantiae extracts; 30 parts of substrate.All the other are the same.
4, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 1 part of medicine Fructus Momordicae charantiae extract; 20 parts of substrate.All the other are the same.
5, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 1 part of medicine Fructus Momordicae charantiae extract; 80 parts of substrate.All the other are the same.
6, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 40 parts of medicine Fructus Momordicae charantiae extracts; 20 parts of substrate.All the other are the same.
7, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 80 parts of medicine Fructus Momordicae charantiae extracts; 80 parts of substrate.Substrate is mannitol: chitosan: sweeting agent is 1: 0.25: 0.025.
Compound method: after getting Fructus Momordicae charantiae extract and be crushed to 80-100 order granularity by prescription, with substrate mixing, tabletting.
8, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 1 part of medicine Fructus Momordicae charantiae extract; 20 parts of substrate.Substrate is mannitol: chitosan: sweeting agent is 1: 0.125: 0.062.All the other are the same.
9, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 30 parts of medicine Fructus Momordicae charantiae extracts; 20 parts of substrate.Substrate is mannitol: chitosan: sweeting agent is 1: 0.2: 0.02.All the other are the same.
10, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 1 part of medicine Fructus Momordicae charantiae extract; 80 parts of substrate.Substrate is mannitol: chitosan: sweeting agent is 1: 0.1: 0.06.All the other are the same.
11, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes
Prescription (weight portion): 60 parts of medicine Fructus Momordicae charantiae extracts; 80 parts of substrate.Substrate is mannitol: chitosan: sweeting agent is 1: 0.19: 0.04.All the other are the same.
Claims (8)
1, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes is made up of medicine and substrate, it is characterized in that (weight portion):
Medicine is Fructus Momordicae charantiae extract 1-80 part;
Substrate 20-80 part;
By the prescription thing of getting it filled, after the pulverizing,, be processed into dosage form with the substrate mixing.
2, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 1 is characterized in that described dosage form is a drop pill, Fructus Momordicae charantiae extract 1-40 part.
3, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 2 is characterized in that described substrate is Macrogol 4000-6000.
4, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 2 is characterized in that described substrate is sodium stearate.
5, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 2 is characterized in that described substrate is glycerol-gelatin.
6, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 2 is characterized in that described substrate is carbamide-polycitric acid.
7, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 2 is characterized in that described substrate is glyceryl stearate.
8, a kind of Fructus Momordicae charantiae Chinese medicine preparation for the treatment of diabetes according to claim 1 is characterized in that described dosage form is a tablet, and described substrate is: mannitol: chitosan: sweeting agent corresponds to 1: 0.25～and 0.125: 0.025～0.062.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031117678A CN1520857A (en) | 2003-01-27 | 2003-01-27 | Diabetes treating bitter gourd traditional Chinese medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031117678A CN1520857A (en) | 2003-01-27 | 2003-01-27 | Diabetes treating bitter gourd traditional Chinese medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1520857A true CN1520857A (en) | 2004-08-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031117678A Pending CN1520857A (en) | 2003-01-27 | 2003-01-27 | Diabetes treating bitter gourd traditional Chinese medicine |
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| CN (1) | CN1520857A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894364A (en) * | 2012-10-19 | 2013-01-30 | 安徽农业大学 | Preparation method of balsam pear/green tea sugar-reducing buccal tablets |
| CN107307417A (en) * | 2017-06-17 | 2017-11-03 | 深圳市领治医学科技有限公司 | A kind of type 2 diabetes patient's nutriment |
-
2003
- 2003-01-27 CN CNA031117678A patent/CN1520857A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102894364A (en) * | 2012-10-19 | 2013-01-30 | 安徽农业大学 | Preparation method of balsam pear/green tea sugar-reducing buccal tablets |
| CN107307417A (en) * | 2017-06-17 | 2017-11-03 | 深圳市领治医学科技有限公司 | A kind of type 2 diabetes patient's nutriment |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |