CN1503796B - 顺-ftc的多晶型物及其它晶型 - Google Patents

顺-ftc的多晶型物及其它晶型 Download PDF

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Publication number
CN1503796B
CN1503796B CN028082850A CN02808285A CN1503796B CN 1503796 B CN1503796 B CN 1503796B CN 028082850 A CN028082850 A CN 028082850A CN 02808285 A CN02808285 A CN 02808285A CN 1503796 B CN1503796 B CN 1503796B
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China
Prior art keywords
ftc
cis
type
iii
dsc
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Expired - Fee Related
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CN028082850A
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English (en)
Chinese (zh)
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CN1503796A (zh
Inventor
K·R·法雷斯
D·劳
Y·胡
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Abbott Laboratories
Gilead Sciences Inc
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Abbott Laboratories
Triangle Pharmaceuticals Inc
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Priority to CN201210146877.2A priority Critical patent/CN102911166B/zh
Priority to CN201210146874.9A priority patent/CN102911165B/zh
Publication of CN1503796A publication Critical patent/CN1503796A/zh
Application granted granted Critical
Publication of CN1503796B publication Critical patent/CN1503796B/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN028082850A 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型 Expired - Fee Related CN1503796B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201210146877.2A CN102911166B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN201210146874.9A CN102911165B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27256001P 2001-03-01 2001-03-01
US60/272,560 2001-03-01
US30960501P 2001-08-02 2001-08-02
US60/309,605 2001-08-02
PCT/US2002/006184 WO2002070518A1 (en) 2001-03-01 2002-03-01 Polymorphic and other crystalline forms of cis-ftc

Related Child Applications (3)

Application Number Title Priority Date Filing Date
CN201210146877.2A Division CN102911166B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN2012101468804A Division CN102942563A (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN201210146874.9A Division CN102911165B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型

Publications (2)

Publication Number Publication Date
CN1503796A CN1503796A (zh) 2004-06-09
CN1503796B true CN1503796B (zh) 2012-07-04

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Family Applications (4)

Application Number Title Priority Date Filing Date
CN028082850A Expired - Fee Related CN1503796B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN201210146874.9A Expired - Fee Related CN102911165B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN2012101468804A Pending CN102942563A (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN201210146877.2A Expired - Fee Related CN102911166B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN201210146874.9A Expired - Fee Related CN102911165B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN2012101468804A Pending CN102942563A (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型
CN201210146877.2A Expired - Fee Related CN102911166B (zh) 2001-03-01 2002-03-01 顺-ftc的多晶型物及其它晶型

Country Status (14)

Country Link
US (3) US6723728B2 (OSRAM)
EP (3) EP1903041B1 (OSRAM)
JP (4) JP5105689B2 (OSRAM)
KR (4) KR101150250B1 (OSRAM)
CN (4) CN1503796B (OSRAM)
AT (2) ATE383355T1 (OSRAM)
AU (1) AU2002335489B2 (OSRAM)
CA (4) CA2788498C (OSRAM)
CY (2) CY1107983T1 (OSRAM)
DE (2) DE60207850T2 (OSRAM)
DK (2) DK1574512T3 (OSRAM)
ES (3) ES2537007T3 (OSRAM)
PT (2) PT1574512E (OSRAM)
WO (1) WO2002070518A1 (OSRAM)

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PT1574512E (pt) * 2001-03-01 2008-03-05 Abbott Lab Formas polimórficas e outras formas cristalinas de cis-ftc
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EA015145B1 (ru) 2003-01-14 2011-06-30 Джилид Сайэнс, Инк. Фармацевтическая композиция и пероральная фармацевтическая дозированная форма (варианты), проявляющие активность в отношении вич-инфекций, лечебный набор и таблетка и способ лечения или предотвращения симптомов или эффектов вич-инфекции
US6943249B2 (en) 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) * 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
WO2009005338A2 (en) * 2007-07-05 2009-01-08 Ultimorphix Technologies B.V. Solid forms ult-i, ult-2 and ult-3 of emtricitabine
EP2350065A1 (en) 2008-11-12 2011-08-03 Lupin Ltd. A novel polymorph of emtricitabine and a process for preparing of the same
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Also Published As

Publication number Publication date
US6723728B2 (en) 2004-04-20
CA2788498A1 (en) 2002-09-12
KR20080065317A (ko) 2008-07-11
ES2299950T3 (es) 2008-06-01
JP2004530660A (ja) 2004-10-07
KR100927024B1 (ko) 2009-11-17
CN102942563A (zh) 2013-02-27
EP1389207A1 (en) 2004-02-18
KR101150250B1 (ko) 2012-06-12
EP1903041B1 (en) 2015-02-18
EP1574512B1 (en) 2008-01-09
CA2690137C (en) 2012-11-13
DK1389207T3 (da) 2006-04-18
US20050026934A1 (en) 2005-02-03
US7544692B2 (en) 2009-06-09
PT1903041E (pt) 2015-06-23
ATE312097T1 (de) 2005-12-15
US20090306114A1 (en) 2009-12-10
DE60224592D1 (de) 2008-02-21
KR20080065316A (ko) 2008-07-11
DE60207850T2 (de) 2006-08-10
CA2788498C (en) 2016-02-16
PT1574512E (pt) 2008-03-05
ES2253544T3 (es) 2006-06-01
US20030060645A1 (en) 2003-03-27
EP1389207B1 (en) 2005-12-07
JP5105689B2 (ja) 2012-12-26
CA2690137A1 (en) 2002-09-12
CN102911165B (zh) 2016-08-17
WO2002070518A1 (en) 2002-09-12
CY1107913T1 (el) 2013-09-04
EP1903041A2 (en) 2008-03-26
DE60207850D1 (de) 2006-01-12
US8637535B2 (en) 2014-01-28
KR101015510B1 (ko) 2011-02-16
CN102911166B (zh) 2016-08-17
CA2439831C (en) 2010-01-12
CN102911165A (zh) 2013-02-06
KR20100091265A (ko) 2010-08-18
JP2009197005A (ja) 2009-09-03
ES2537007T3 (es) 2015-06-01
KR20040002871A (ko) 2004-01-07
JP2015028045A (ja) 2015-02-12
EP1903041A3 (en) 2008-04-23
DE60224592T2 (de) 2009-01-29
DK1574512T3 (da) 2008-03-03
CY1107983T1 (el) 2013-09-04
CA2439831A1 (en) 2002-09-12
JP2013040192A (ja) 2013-02-28
CN1503796A (zh) 2004-06-09
AU2002335489B2 (en) 2008-06-05
ATE383355T1 (de) 2008-01-15
CA2867970A1 (en) 2002-09-12
EP1574512A1 (en) 2005-09-14
CN102911166A (zh) 2013-02-06

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