CN1500476A - Microporous film distilled condensation method of aqueous traditional Chinese medicine extract - Google Patents
Microporous film distilled condensation method of aqueous traditional Chinese medicine extract Download PDFInfo
- Publication number
- CN1500476A CN1500476A CNA021386366A CN02138636A CN1500476A CN 1500476 A CN1500476 A CN 1500476A CN A021386366 A CNA021386366 A CN A021386366A CN 02138636 A CN02138636 A CN 02138636A CN 1500476 A CN1500476 A CN 1500476A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- aqueous
- extraction liquid
- film
- medicine extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 34
- 238000000034 method Methods 0.000 title abstract description 6
- 238000009833 condensation Methods 0.000 title description 3
- 230000005494 condensation Effects 0.000 title description 3
- 239000012528 membrane Substances 0.000 claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 12
- 238000004519 manufacturing process Methods 0.000 claims abstract description 8
- 238000010521 absorption reaction Methods 0.000 claims abstract description 6
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 6
- 239000011780 sodium chloride Substances 0.000 claims abstract description 6
- 239000007788 liquid Substances 0.000 claims description 27
- 238000000605 extraction Methods 0.000 claims description 22
- 238000004821 distillation Methods 0.000 claims description 14
- 239000012141 concentrate Substances 0.000 claims description 9
- 239000012510 hollow fiber Substances 0.000 claims description 7
- -1 polypropylene Polymers 0.000 claims description 5
- 239000004743 Polypropylene Substances 0.000 claims description 3
- 238000001704 evaporation Methods 0.000 claims description 3
- 230000008020 evaporation Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000012982 microporous membrane Substances 0.000 claims description 3
- 229920001155 polypropylene Polymers 0.000 claims description 3
- 239000002033 PVDF binder Substances 0.000 claims description 2
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 239000000498 cooling water Substances 0.000 claims description 2
- 229950000845 politef Drugs 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 claims description 2
- 238000010791 quenching Methods 0.000 claims description 2
- 238000005516 engineering process Methods 0.000 abstract description 7
- 238000005086 pumping Methods 0.000 abstract 1
- 235000008504 concentrate Nutrition 0.000 description 8
- 239000000243 solution Substances 0.000 description 7
- 238000003860 storage Methods 0.000 description 5
- 239000008862 fructus schizandrae, radix ginseng, radix ophiopogonis drug combination Substances 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000008719 thickening Effects 0.000 description 3
- 230000004071 biological effect Effects 0.000 description 2
- 235000012489 doughnuts Nutrition 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 239000008358 core component Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 235000010985 glycerol esters of wood rosin Nutrition 0.000 description 1
- 235000014666 liquid concentrate Nutrition 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000008542 thermal sensitivity Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
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- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The present invention is the production process of concentrating water extracting solution of Chinese medicine via membrane concentration technology. Hydrophobic microporous film is adopted, and there are water extracting solution of Chinese medicine at 30-60 deg.c on one side of the membrane and NaCl solution for absorbing water vapor or certain vacuum on the other side. Water vapor diffuses via the microporous film from the water solution side to the other side for absorption or vacuum pumping suction. The present invention is superior to available high temperature concentration process in that the low temperature concentration of Chinese medicine extracting solution has less influence on the medicine quality and has all the effective components in the Chinese medicine extracting solution maintained. The present invention has wide application foreground, especially in concentrating water solution of thermosensitive and small molecular matter.
Description
Technical field
The present invention relates to the concentrated production method of Chinese medicine extraction liquid, especially the distillation of the film of aqueous Chinese medicine extraction liquid concentrates production method, is applicable to that the aqueous Chinese medicine extraction liquid distills spissated occasion.
Background technology
It is necessary technical process during aqueous solution such as Chinese medicine preparation is produced that distillation concentrates, and is one of key link that influences the Chinese patent medicine product quality.At present concentration technique and the equipment that adopts has: open type concentration tank, single-action and economic benefits and social benefits or three-effect evaporation and condensation unit, vacuum film concentrate etc., and its operative temperature is generally more than 80 ℃.Higher thickening temperature can reduce the biological activity and the effective ingredient of Chinese medicine extraction liquid, influences the presentation quality of Chinese patent medicine, and is obvious especially to the influence of thermal sensitivity Chinese medicine preparation.Adopt general ultrafiltration membrance filter technology, though what also can acquire a certain degree concentrates, there is not crown_interception for being lower than thousands of materials to several ten thousand molecular weight, so, have a strong impact on the drug effect that Chinese medicine preparation is formed by complicated composition synergism along with the loss of concentration process effective ingredient.
Summary of the invention
The objective of the invention is to overcome the shortcoming of prior art, provide that a kind of technology is simple, thickening temperature is low, the concentrated solution quality is good, the composition of remaining valid, easy to operate aqueous Chinese medicine extraction liquid film distillation concentrate production method.
A kind of aqueous Chinese medicine extraction liquid film distillation concentrates production method, it is characterized in that adopting the distillatory mode of film, promptly in the membrane module of hydrophobic hollow fiber, one side of film is that temperature is at 30-60 ℃ of aqueous Chinese medicine extraction liquid, the opposite side of film is NaCl solution or cooling water or the above space of vacuum 0.03MPa of concentration expressed in percentage by weight 20-45%, water evaporation in the aqueous Chinese medicine extraction liquid sees through membranous wall, by NaCl solution absorption or the water quench or the vacuum draw of opposite side, thereby reach concentrating of aqueous Chinese medicine extraction liquid.The membrane material that the hydrophobic hollow fiber membrane module is adopted is polypropylene or polyethylene or politef or polyvinylidene fluoride dewatering hollow fiber microporous membrane.
The present invention compared with prior art, thickening temperature is low, thereby keeps the presentation quality of biological activity, effective ingredient and the Chinese patent medicine of Chinese medicine extraction liquid, technology is simple, and is easy to operate, has bigger implementary value and economic results in society.
Description of drawings
Fig. 1 is a vacuum aspiration aqueous Chinese medicine extraction liquid film distillation concentration technology flow chart.
Fig. 2 is a solution absorption method aqueous Chinese medicine extraction liquid film distillation concentration technology flow chart.
Wherein 1-Chinese medicine extraction liquid storage tank, 2-recycle liquid pump, 3-membrane module, 4-vacuum draw pump, 5,6-heat exchanger, 7-condensed water storage tank, 8-absorption liquid storage tank.
The specific embodiment
Embodiment 1:
Press shown in the accompanying drawing 1: its core component membrane module, adopt hydrophobic polypropylene hollow fiber microporous membrane, its air penetrability＞6 * 10
-2Cm
3(STP)/cm
2.S.cmHg, two ends are used bi-component polyurethane ester gum or epoxide-resin glue to seal and are made into membrane module.One side of film be temperature at 30-60 ℃ of aqueous Chinese medicine extraction liquid, the opposite side of film is the space of vacuum more than 0.03MPa.Chinese medicine extraction liquid adopts new fresh Herba Leonuri to extrude liquid, this new fresh Herba Leonuri is extruded liquid after filtering, send into membrane module 3 distillations by recycle liquid pump 2 and heat exchanger 5 and concentrate, the water vapour that sees through the doughnut membrane micropore obtains pure water by vacuum pump 4 suctions through heat exchanger 6 condensations.Concentrated solution after the film distillation returns storage tank 1, concentrates through the distillation that repeatedly circulates, and the concentration expressed in percentage by weight that makes fresh Herba Leonuri extrude juice reaches 10-30%.
Embodiment 2:
Press shown in the accompanying drawing 2: adopt and the membrane module of example 1 with performance.One side of film be temperature at 30-60 ℃ of aqueous Chinese medicine extraction liquid, the opposite side of film is the NaCl solution of concentration expressed in percentage by weight 20-45%.Chinese medicine extraction liquid adopts SHENMAI ZHUSHEJI, and this SHENMAI ZHUSHEJI is sent into membrane module 3 distillations by circulating pump 2 and heat exchanger 5 and concentrated, and the water vapour by the doughnut membrane micropore is absorbed by the absorption liquid that the film opposite side circulates.Concentrated solution after the film distillation returns storage tank 1, through repeatedly the circulation distillation is concentrated, makes the concentration expressed in percentage by weight of SHENMAI ZHUSHEJI reach more than 10%.
Claims (2)
1, a kind of aqueous Chinese medicine extraction liquid film distillation concentrates production method, it is characterized in that adopting the distillatory mode of film, promptly in the membrane module of hydrophobic hollow fiber, one side of film is that temperature is at 30-60 ℃ of aqueous Chinese medicine extraction liquid, the opposite side of film is that the NaCl solution of concentration expressed in percentage by weight 20-45% or cooling water or vacuum are the above space of 0.03MPa, water evaporation in the aqueous Chinese medicine extraction liquid sees through membranous wall, by NaCl solution absorption or the water quench or the vacuum draw of opposite side, thereby reach concentrating of aqueous Chinese medicine extraction liquid.
2, production method according to claim 1 is characterized in that the membrane material that the hydrophobic hollow fiber membrane module is adopted is polypropylene or polyethylene or politef or polyvinylidene fluoride dewatering hollow fiber microporous membrane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021386366A CN1500476A (en) | 2002-11-19 | 2002-11-19 | Microporous film distilled condensation method of aqueous traditional Chinese medicine extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021386366A CN1500476A (en) | 2002-11-19 | 2002-11-19 | Microporous film distilled condensation method of aqueous traditional Chinese medicine extract |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1500476A true CN1500476A (en) | 2004-06-02 |
Family
ID=34231759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA021386366A Pending CN1500476A (en) | 2002-11-19 | 2002-11-19 | Microporous film distilled condensation method of aqueous traditional Chinese medicine extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1500476A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106823802A (en) * | 2010-09-22 | 2017-06-13 | Oasys水有限公司 | Osmotic drive membrane process and system and the method for driving solute to reclaim |
| CN108854551A (en) * | 2018-06-12 | 2018-11-23 | 合肥丰洁生物科技有限公司 | A kind of high-efficiency plant extraction film concentrator |
-
2002
- 2002-11-19 CN CNA021386366A patent/CN1500476A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106823802A (en) * | 2010-09-22 | 2017-06-13 | Oasys水有限公司 | Osmotic drive membrane process and system and the method for driving solute to reclaim |
| CN108854551A (en) * | 2018-06-12 | 2018-11-23 | 合肥丰洁生物科技有限公司 | A kind of high-efficiency plant extraction film concentrator |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |