CN1498600A - Laseer heat treatment appliance for treating tumour - Google Patents
Laseer heat treatment appliance for treating tumour Download PDFInfo
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- CN1498600A CN1498600A CNA02148323XA CN02148323A CN1498600A CN 1498600 A CN1498600 A CN 1498600A CN A02148323X A CNA02148323X A CN A02148323XA CN 02148323 A CN02148323 A CN 02148323A CN 1498600 A CN1498600 A CN 1498600A
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- laser
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- tumor
- laserthermia
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- Thermotherapy And Cooling Therapy Devices (AREA)
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Abstract
A laser thermotherapeutic apparatus for treating tumor (gastric cancer, rectum cancer, esophagus cancer, etc) is composed of laser device, transmitting optical fibre, and thermotherapeutic probe in direct contact with tumor. It features that the Nd:YAG (1319nm), Nd:YAP (1341 nm), or semiconductor diode (1310 nm) is used as the laser source as they has weak penetrability and can be easily absorbed by tissue.
Description
Technical field
The present invention relates to a kind of armarium, especially relate to the heat treatment unit of fritter tumor.
Background technology
Tumor has been found an existing very long so far end history, but how real it is cured is a difficult problem of puzzlement medical circle always.Therapeutic Method the earliest is to utilize operation to carry out, so therefore the doctor of large quantities of operation time exquisitenesses becomes famous.Develop by leaps and bounds along with medical science applied, the treatment of tumor and cancer also be constantly obtain along with the development of medical science always progressive, its cure rate constantly rises, Therapeutic Method is also constantly weeded out the old and bring forth the new, treatment meanss such as radiotherapy, chemotherapy and immunotherapy have appearred in succession, but the medical expense height of ocal resection, and some patient is difficult to bear economically, the side effect that the radiation and chemotherapy Therapeutic Method produces patient clearly, outpatients mental state is difficult to accept sometimes during treatment.Nowadays, the thermotherapy therapy that tumor occurred, it is a kind of method that heats to treat tumor, it had both utilized relevant physical energy to precipitate in tissue and had produced heat effect, make the tumor tissues temperature rise to effective treatment temperature, and keep certain hour, tumor is dwindled or eliminate a kind of Therapeutic Method of the purpose of unlikely again damage normal structure to reach.The neoplastic fevers therapy has become the fifth-largest therapy after operation, radiotherapy, chemotherapy and immunotherapy, is a kind of new independent means of treatment tumor.Thermotherapy is killing tumor cell effectively, improves patient's life quality, prolongs patient's life, thereby is referred to as " green remedy " by international medical community and is subjected to using widely.
Summary of the invention
Laser is a kind of light source of high brightness, can produce heat effect to biological tissue when its irradiating biological is organized, yet laser has various wave band, and the laser of different-waveband is different to the effect that biological tissue produces heat effect.Excite the Nd:YAG laser crystal can produce the laser of 1319nm wave band, or excite the Nd:YAP laser crystal can produce the laser of 1341nm wave band or the laser that the employing semiconductor diode can produce the 1310nm wave band, the characteristics of these wave band of laser are that they are more intense to the absorbability of biological tissue, so when their irradiating biologicals are organized, can only reach the more shallow position of biological tissue owing to strong absorbability, and modern medicine is told us, when the temperature of heating cancerous cell reached 45 ℃, cancerous cell will be dead.Characteristics so the laser that we just can utilize 1319nm or 1341nm or 1310nm wave band is strong to biological tissue's absorbability a little less than the penetration capacity are with the laser of these wave bands thermotherapy source as the fritter tumor thermotherapy.
We will understand the true temperature of tumor site constantly during thermotherapy, coming according to this to control thermotherapy temperature at any time and being unlikely to heats the temperature of tumor site too high, fluorescence formula fibre optic thermometer is to utilize the light intensity of natural fluoresence material sulfuration dioxy two lanthanum excited fluorescences emission recently to realize thermometric, when temperature change, variation has also taken place in the intensity of its excited fluorescence emission spectra, be that fluorescence intensity changes with temperature, when measuring the change amount of fluorescence intensity, by calculating, just can obtain tested temperature.It is the absolute measurement of temperature, has very high sensitivity and certainty of measurement in middle low temperature range.In the example of this thermal therapeutic apparatus, the fibre optic temperature sensor that we utilized is to have used this fluorescent optical fiber temperature sensor, the emission luminescent material that it utilized is sulfuration dioxy two lanthanums, select spectral line to do fluorescence intensity measurement at 540nm and 630nm, these two residing wave bands of spectral line during with our thermotherapy the laser wavelength of employed 1319nm or 1341nm or 1310nm wave band be different, so be not have influence to the measurement result of fluorescence optical fiber as the laser in thermotherapy source.
The object of the present invention is to provide a kind of laserthermia instrument of being formed by laser instrument (A), Transmission Fibers (B), laserthermia instrument probe device (C) that has not yet to see report, it adopts laser to do the thermotherapy source, thermotherapy source laser wave band is the laser of 1319nm or 1341nm or 1310nm wave band, have the high sensitivity temperature detection function, can heat to treat the fritter tumor.
Realize that technical scheme of the present invention is: the structure of this tumor laserthermia instrument as shown in Figure 1, it is made up of (A), (B), (C) three parts, wherein (A) is laser instrument, can export the laser instrument that excites Nd:YAG laser crystal output 1319nm wave band, or excite the laser instrument of Nd:YAP laser crystal output 1341nm wave band or adopt semiconductor diode to export the laser instrument of 1310nm wave band, this laser instrument can be provided by laser instrument manufacturer; (B) be the laser fiber that is used for transmitting the thermotherapy source, on sale on the market; (C) be the temperature probe device, this probe apparatus is made up of with the laser fiber (8) in thermotherapy source bottom (2), the opening (3) of shell, fixture (4), first through hole (5), second through hole (6), optical fiber sensing probe (7), the transmission treatment of shell (1), shell, and its structural representation as shown in Figure 2.
The probe apparatus of this thermal therapeutic apparatus, adopt full-sealing device, laser fiber delivery and thermal detector together are placed in a kind of hermetic device, like this, when carrying out thermotherapy, we can survey the temperature of tumor site, but are placed in the sealing device owing to the laser fiber outfan simultaneously, it can not contact with tissue fluid, has guaranteed lighting effect.Adopted thermal detector again, the temperature measurement accuracy height, temperature probe contacts with tumor by sealing device, can truly survey the temperature of tumor site when treating, and the temperature foundation of science is provided for clinical treatment.
This laserthermia instrument can be applicable to thermotherapies such as gastric cancer, rectal cancer, esophageal carcinoma.
This laserthermia instrument has some following characteristics:
1, the laser instrument of this laserthermia instrument can be laser instrument or the laser instrument of 1341nm wave band or the semiconductor diode laser of 1310nm wave band that can export the 1319nm wave band, because the laser of 1319nm or 1341nm wave band or 1310nm wave band is strong to the absorbability of biological tissue, so penetration capacity is more weak, the fritter tumor is heated to treat thereby the surface that they can see through tumor reach the more shallow tissue of tumor.
2, the temperature probe volume is small in the hyperthermia applicator device of this laserthermia instrument, and the use that matches with laser transmission fiber has constituted a kind of treatment probe of full microminiaturization, and can be crooked, can be inserted to each pipeline in the body by endoscope path way.
3, the hyperthermia applicator device of this laserthermia instrument has a shell, adopt various surgical grade stainless steels, probe places outer casing inner wall, and shell can contact with the pathological changes human body, do not contact simultaneously so optical fiber can truly be surveyed the human body temperature, guaranteed the cleaning of fibre-optical probe with the pathological changes human body.
Description of drawings
Fig. 1 is the sketch map of this tumor laserthermia instrument, and wherein (A) is laser instrument, (B) is the optical fiber of transmission laser, (C) is the thermotherapy temperature probe.
Fig. 2 is a thermal therapeutic apparatus probe sketch map, and wherein (1) is shell, and (2) are the bottoms of shell, (3) be the opening of shell, (4) are fixtures, and (5) are first through holes, (6) be second through hole, (7) are the optical fiber sensing probes, and (8) are the laser fiber of transmission treatment with the thermotherapy source.
The specific embodiment
In the example of the present invention, thermal therapeutic apparatus laser instrument (A) is the laser that adopts semiconductor diode output 1310nm wave band, it is provided by the special photoelectricity in sea Co., Ltd, export with optical fiber (B), the outfan of optical fiber is positioned in the thermal therapeutic apparatus probe, and thermal therapeutic apparatus probing shell (1) is coniform, and material therefor is a quartz glass, bottom (2) is airtight, and the other end has an opening (3).Located fixture (4) at opening (3), fixture (4) is made with silica glass material equally, its outward appearance is the approximate circle taper, size is smaller than shell, major part can stretch in the shell (1), but the end is thicker, opening (3) can be sealed, and is tightly connected with glue with the contact position of opening.Be provided with two through hole (5), (6) on fixture (4), be equivalent to two grooves and place two optical fiber, optical fiber is placed in the enclosure like this, can not take place to move on a large scale.We use fluorescent optical fiber temperature sensor to be used as temperature measuring equipment, optical fiber sensing probe (7) one ends are positioned over wall place within the shell bottom (2) by first through hole (5), the external optical fiber sensing control system of the other end, the contact position of itself and first through hole (5) is sealedly and fixedly connected with glue.Laser transmission fiber (8) one ends place wall place within the shell bottom (2) by second through hole (6), the external laser instrument of the other end, and the contact position of itself and through hole is sealedly and fixedly connected with glue.
When using this laserthermia instrument,, judge the size of tumor mass,, then can use this laserthermia instrument to treat if tumor mass is smaller earlier by ultrasonic examination.During use, pass through endoscope, hyperthermia applicator is directly placed the tumor site that to receive treatment, open the laser generator of this laserthermia instrument then, output is heated to treat tumor by the 1310nm wave band of laser that semiconductor diode produced, and surveys and adjust laser power by the temperature of fluorescence optical fiber hygrosensor, within 45 ℃, guaranteed when killing cancerous cell, can not make normal tissue cell to come to harm heating and temperature control.
Claims (2)
1. tumor laserthermia instrument, it is characterized in that: this thermal therapeutic apparatus is made up of laser instrument (A), Transmission Fibers (B), laserthermia instrument probe device (C), and the laser that is transmitted in the Transmission Fibers (B) is to excite the 1319nm wave band that the Nd:YAG laser crystal produced or excite the 1341nm wave band that the Nd:YAP laser crystal produced or adopt the laser of the 1310nm wave band that semiconductor diode produces.
2. tumor laserthermia instrument as claimed in claim 1 is characterized in that: said laserthermia instrument probe device (C) is made up of with the laser fiber (8) in thermotherapy source bottom (2), the opening (3) of shell, fixture (4), first through hole (5), second through hole (6), optical fiber sensing probe (7), the transmission treatment of shell (1), shell.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA02148323XA CN1498600A (en) | 2002-11-04 | 2002-11-04 | Laseer heat treatment appliance for treating tumour |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA02148323XA CN1498600A (en) | 2002-11-04 | 2002-11-04 | Laseer heat treatment appliance for treating tumour |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1498600A true CN1498600A (en) | 2004-05-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA02148323XA Pending CN1498600A (en) | 2002-11-04 | 2002-11-04 | Laseer heat treatment appliance for treating tumour |
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| CN (1) | CN1498600A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101132730B (en) * | 2005-03-04 | 2010-06-23 | 恩杜森斯公司 | medical apparatus system having optical fiber load inductive capacity |
| CN103217752A (en) * | 2012-08-17 | 2013-07-24 | 上海菲捷实业有限公司 | Optical fiber front end structure of yttrium aluminium garnet (YAG) laser |
| CN104840251A (en) * | 2015-05-07 | 2015-08-19 | 上海大学 | Laser thermal therapy probe based on photothermal effect of optical fiber material |
| CN107412957A (en) * | 2017-07-12 | 2017-12-01 | 华东师范大学 | A kind of photo-thermal therapy probe based on photo-thermal nano material |
| CN107854777A (en) * | 2017-11-07 | 2018-03-30 | 中国地质大学（武汉） | Three-dimensional porous graphene assembling medicine temperature control chemotherapy and thermotherapy stomach and intestine tumor device |
| CN108853749A (en) * | 2018-05-16 | 2018-11-23 | 广州医科大学附属肿瘤医院 | A kind of target head protective case of Dispoable medical laserthermia |
| CN109069857A (en) * | 2017-03-08 | 2018-12-21 | 拉尔夫·齐珀 | Method for treating the symptom of pelycalgia, chronic prostatitis and/or overactive bladder |
| CN109276818A (en) * | 2018-11-16 | 2019-01-29 | 中聚科技股份有限公司 | A kind of laser fiber shield |
-
2002
- 2002-11-04 CN CNA02148323XA patent/CN1498600A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101132730B (en) * | 2005-03-04 | 2010-06-23 | 恩杜森斯公司 | medical apparatus system having optical fiber load inductive capacity |
| CN101874729B (en) * | 2005-03-04 | 2012-01-25 | 恩杜森斯公司 | Medical apparatus system having optical fiber load sensing capability |
| CN103217752A (en) * | 2012-08-17 | 2013-07-24 | 上海菲捷实业有限公司 | Optical fiber front end structure of yttrium aluminium garnet (YAG) laser |
| CN104840251A (en) * | 2015-05-07 | 2015-08-19 | 上海大学 | Laser thermal therapy probe based on photothermal effect of optical fiber material |
| CN109069857A (en) * | 2017-03-08 | 2018-12-21 | 拉尔夫·齐珀 | Method for treating the symptom of pelycalgia, chronic prostatitis and/or overactive bladder |
| CN107412957A (en) * | 2017-07-12 | 2017-12-01 | 华东师范大学 | A kind of photo-thermal therapy probe based on photo-thermal nano material |
| CN107412957B (en) * | 2017-07-12 | 2019-09-10 | 华东师范大学 | A kind of photo-thermal therapy probe based on photo-thermal nano material |
| CN107854777A (en) * | 2017-11-07 | 2018-03-30 | 中国地质大学（武汉） | Three-dimensional porous graphene assembling medicine temperature control chemotherapy and thermotherapy stomach and intestine tumor device |
| CN108853749A (en) * | 2018-05-16 | 2018-11-23 | 广州医科大学附属肿瘤医院 | A kind of target head protective case of Dispoable medical laserthermia |
| CN109276818A (en) * | 2018-11-16 | 2019-01-29 | 中聚科技股份有限公司 | A kind of laser fiber shield |
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