CN2574631Y - Abdominocentesis fixator - Google Patents

Abdominocentesis fixator Download PDF

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Publication number
CN2574631Y
CN2574631Y CN 02286746 CN02286746U CN2574631Y CN 2574631 Y CN2574631 Y CN 2574631Y CN 02286746 CN02286746 CN 02286746 CN 02286746 U CN02286746 U CN 02286746U CN 2574631 Y CN2574631 Y CN 2574631Y
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China
Prior art keywords
laser
optical fiber
probe
temperature
shell
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Expired - Fee Related
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CN 02286746
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Chinese (zh)
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林授群
林文雄
黄见洪
林宗志
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Fujian Institute of Research on the Structure of Matter of CAS
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Fujian Institute of Research on the Structure of Matter of CAS
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Abstract

The utility model relates to a probe device for laser thermal therapeutic apparatuses, which can carry out thermal therapeutic treatment to tumors by using the characteristic of the strong laser piercing power of an 808 nm wave band existed by Nd: YAG, 1064 nm and a semiconductor pump. The appearance of the probe device is in the shape of a cylinder. One end is smooth and closed and can directly contact with tumors of pathological changes. The other end is provided with an opening and a fixing device sealing the open end. A laser transmitting optical fiber and an optical fiber temperature probe are arranged in a casing. The optical fiber temperature sensing probe can directly contact with the tumors of pathological changes through the casing and can effectively detect the actual temperature at the tumor position during thermotherapy.

Description

A kind of laserthermia instrument probe device
Technical field
This utility model relates to a kind of armarium, especially relates to tumor treatment equipment.
Background technology
Medical science has had the development of leap since 1950's, people are gratified for the obtained significant achievements of modern medicine invariably, the progress of treatment of cancer also is fruitful, its cure rate by less than 10% so far the total cure rate of various tumors rise to more than the 40-50%.Yet unfortunately, up to now, cancer remains the formidable enemy of serious threat human health, and modern medicine mainly is that operative treatment cooperates radiation therapy or chemotherapy to tumor treatment at present.But because factor such as the excessive or position of tumor is incorrect, operative therapy poor effect sometimes, radiation therapy and chemotherapy produce to a certain degree harm to human body, so the neoplastic fevers therapy has obtained application widely as a kind of means of Comprehensive Treatment cancer.
Along with the appearance of laser and the high speed development of its technology, people now can use laser and treat cancer as the thermotherapy source.Laser can produce heat effect to biological tissue during with laser direct irradiation biological tissue, and the effect that the laser of different-waveband produces heat effect is inequality.The bulk tumor serious threat mankind's is healthy, and operation can not cause the recurrence of tumor fully with its excision sometimes.Nowadays, by the laser technology that excites the Nd:YAG laser crystal to produce 1064nm wave band and the semiconductor pumped 808nm wave band that excites is very sophisticated, the laser piercing power of this two wave band is strong, can enter into the darker tissue of inside tumor heats tumor cell, and modern thermal biology points out 42 ℃-45 ℃ temperature just can kill and wound cancerous cell, so, we can utilize 1064nm and the strong characteristics of 808nm wave band of laser penetration power, pass through endoscope, laser is imported in the human body by fiber-optic transfer, prospective tumor is directly carried out laser irradiation.Utilize hygrosensor to survey the temperature of tumor irradiation place and the size of passing through the control laser power, the laser irradiation temperature is controlled at 42 ℃-45 ℃, just can effectively kill the cancerous cell in the bulk tumor, remove patient's cancer pain.But because former laser equipment is perfect inadequately, such as, fiber optic conduction laser belongs to contactless, and easily is organized the liquid pollution, influences the laser irradiation effect.When the laser irradiation tumor site, can't science judge whether biological tissue overheated, reason just is that the optical fiber head of transmission laser does not in the past have temperature measuring equipment, clinically only with the watt level of laser with utilize the distance between endoscopic observation laser beam emitting head and the tumor to judge temperature, therefore, reduced the efficient of heating therapy.In some patent documents,, measure temperature with thermocouple, but its volume is bigger than normal as " photothermal laser probe " (application number 96101822.4), " contact laser probe unit in cavity " (application number 97101217.2), its complex structure, volume is big.
Summary of the invention
Fluorescence formula fibre optic thermometer is that a kind of light intensity of certain natural fluoresence material excited fluorescence emission of utilizing recently realizes thermometric, when temperature change, variation has also taken place in the intensity of its excited fluorescence emission spectra, be that fluorescence intensity changes with temperature, when measuring the change amount of fluorescence intensity, by Microcomputer Calculation, just can obtain tested temperature.It is a kind of novel optical fiber temperature measuring method, and it can realize the absolute measurement of temperature, and certainty of measurement is not subjected to the influence of measured body slin emissivity, has very high sensitivity and certainty of measurement in middle low temperature range.In example of the present invention, the fibre optic temperature sensor that we utilized is to have used fluorescent optical fiber temperature sensor, the emission luminescent material that it utilized is sulfuration dioxy two lanthanums, select spectral line to do fluorescence intensity measurement at 540nm and 630nm, these two residing wave bands of spectral line during with our thermotherapy employed 1064nm be different with the 808nm laser wavelength, so used laser can not cause error to the fluorescence optical fiber measurement during treatment.Owing to adopt the fine small probe of full gloss, it can directly enter in the human body with laser fiber and not account for too large volume, so the present invention makes full use of the little advantage of optical fiber volume, a kind of brand-new laserthermia instrument probe device that laser fiber and fluorescence thermometric optical fiber are connected as a single entity, it has overcome above-mentioned shortcoming, volume is little, and various surgical grade stainless steels can directly be passed through the housing contacts tumor, detect the true temperature of tumor site, for thermotherapy provides the temperature basis for estimation of science, improve the efficient of laserthermia.
So the purpose of this utility model provides a kind of laserthermia instrument probe device of very miniaturization, its small-sized volume more can be accepted by patient.
The technical scheme that realizes this utility model purpose is:
It uses fibre optic temperature sensor to measure temperature, uses a transparent nontoxic material to make shell (1) and is cylindric coniform or very thin needle-like, and the optical fiber (8) of optical fiber sensing probe (7) and transmission laser all is placed in the shell (1).Shell one end (3) opening, bottom (2) is smooth airtight, and opening (3) is equipped with two through hole (5) (6) with a fixture (4) sealing on the fixture (4), two optical fiber passes the bottom that two through hole and an end place shell respectively, and the other end connects instrumentation control system separately.Because the development of laser technology now, can produce Nd:YAG, the laser technology of 1064nm wave band and the semiconductor pumped 808nm wave band that excites is very sophisticated, as long as any medical laser device that can export this two wave band of laser is made outfan with the laser fiber of this probe, the fibre optic temperature sensor that cooperates this probe more just has been assembled into a laserthermia instrument.
Because the present invention adopts sealing setting, laser transmission fiber is positioned in the shell, so can directly device be positioned over the tumor site that will treat, laser fiber can not contact with tissue fluid, adopt the column laser fiber, increased laser irradiation and amass the enhancing therapeutic effect.Adopted the fluorescence optical fiber temperature sensing probe again, the temperature of the tumor site of can direct detection receiving treatment, the temperature measurement accuracy height can come heating and cooling according to the power that measured temperature is controlled laser at any time, not only improved therapeutic efficiency, but also the foundation of science is provided for clinical treatment.
The present invention is simple in structure, practicality reasonable in design, and it has following advantage:
1, temperature probe is that fiber optic materials is made in this laserthermia instrument probe device, and non-metal conductor has electrical insulating property, advantages such as no eddy current and heat effect, and it still is the absolute measurement of temperature, rather than emittance, and therefore, its precision and slin emissivity are irrelevant.Fibre optic temperature sensor adopts optical fiber fluorescence temperature sensor, and the optical fiber front end is coated with a fluorescent material layer, adds the tetrafluoroethene protective layer again in the optical fiber periphery.This pick off temperature measurement accuracy height, in 0~100 ℃ temperature-measuring range, the precision of continuous temperature measurement is 0.5 ℃ (in comprising that continuous use drifts in), so the temperature when we can understand tumor thermotherapy at any time also makes a large amount of normal tissue cells suffer damage when having avoided the laser irradiation tumor.
2, this laserthermia instrument probe crust of the device silica glass material, the optical fiber sensing probe places in the shell, shell can contact with the pathological changes human body, does not contact with the pathological changes human body simultaneously so optical fiber can truly be surveyed the human body temperature, has guaranteed the cleaning of fibre-optical probe.
3, this laserthermia instrument probe device is positioned over laser transmission fiber in the shell, avoided contacting of laser irradiation probe and tissue fluid, utilize 1064nm and the strong characteristics of 808nm wave band of laser penetration capacity, can carry out thermotherapy to the bulk tumor, adopt the column laser fiber, increase the area of thermotherapy zone laser irradiation, improved the utilization rate of laser power, strengthened curative effect.
4, this laserthermia instrument probe device volume is very small, whole probe external diameter is only about 1 centimetre, simple in structure, devices such as no electric wire, patient is acceptant, and can be crooked, is inserted to each pipeline in the body by endoscope path way, even it is tiny for resembling the bronchus, crooked and also can carry out thermotherapy at the canceration position of depths.
This probe can be applicable to gastric cancer, cervical cancer, rectal cancer, the laserthermia of esophageal carcinoma etc.
Description of drawings
Accompanying drawing is a structural representation of the present invention, and wherein (1) is shell, and (2) are the bottoms of shell, (3) be the opening of shell, (4) are fixtures, and (5) are first through holes, (6) be second through hole, (7) are the optical fiber sensing probes, and (8) are laser fibers.
The specific embodiment
We use the fluorescence optical fiber temperature sensing probe to be used as temperature measuring equipment, and in the accompanying drawings, shell (1) is cylindric, are made with silica glass material, and bottom (2) are airtight, and the other end (3) has an opening.Located a fixture (4) at opening (3), fixture (4) is made with silica glass material equally, and its outward appearance is coniform, opening (3) can be sealed, and is tightly connected with glue with the contact position of opening 3.Be provided with two through hole (5), (6) on fixture (4), be equivalent to two grooves and place two optical fiber, optical fiber is placed in the enclosure like this, can not take place to move on a large scale.Optical fiber sensing probe (7) one ends by first through hole (5) place the bottom (2) of shell locate within on the wall, the external optical fiber sensing of the other end control system of popping one's head in is sealedly and fixedly connected with glue with the contact position of through hole.Laser transmission fiber (8) one ends place wall place within the bottom (2) of shell by second through hole (6), the external laser instrument of the other end, and the contact position of itself and through hole is sealedly and fixedly connected with glue.
During use, the laser transmission fiber (8) of this probe is connected to the laser output of laser instrument, the fibre optic temperature sensor of this probe (7) other end is connected to the temperature-sensing system of fluorescence temperature sensor, pass through endoscope, this probe directly is positioned over the tumor site that to accept thermotherapy, open laser, thermometric and the through-put power of controlling laser by fluorescent optical fiber temperature sensor (7), the temperature of laser irradiation biological tissue is controlled at 42 ℃-45 ℃, like this, the cell of normal structure is come to harm.

Claims (2)

1, a kind of laserthermia instrument probe device, comprise shell (1), fixture (4), thermal detector (7), laser fiber output lead (8), shell (1) is cylindric, shell (1) bottom (2) is smooth airtight, shell (1) other end (3) opening, opening (3) seals with fixture (4), fixture (4) is connected as a single entity thermal detector (7) and laser fiber (8), fixture is equipped with two through hole on (4), thermal detector (7) places in the glass-tube by first through hole (5), laser fiber (8) passes second through hole (6) and places in the glass-tube, it is characterized in that: said thermal detector is a fibre optic temperature sensor.
2, laserthermia instrument probe device as claimed in claim 1 is characterized in that: said shell (1) is coniform or very thin needle-like.
CN 02286746 2002-11-04 2002-11-04 Abdominocentesis fixator Expired - Fee Related CN2574631Y (en)

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CN 02286746 CN2574631Y (en) 2002-11-04 2002-11-04 Abdominocentesis fixator

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757739A (en) * 2008-12-25 2010-06-30 上海复旦张江生物医药股份有限公司 Optical-fiber sleeve tube for vaginas and cervixes
CN101347657B (en) * 2007-07-17 2012-02-01 深圳市蓝韵实业有限公司 Ultrasonic probe fixture mechanism applied to ultrasonic tumor treatment system
CN104768489A (en) * 2012-11-08 2015-07-08 皇家飞利浦有限公司 Interventional device, method of assembling, and assembling system
CN105120948A (en) * 2013-04-30 2015-12-02 临床激光热疗系统公司 Apparatus and method for controlling immunostimulating laser thermotherapy
CN105496637A (en) * 2016-01-28 2016-04-20 中国医科大学附属第一医院 Equipment for inducing body immunity to resist cervical human papilloma viral infection
CN106691675A (en) * 2015-07-24 2017-05-24 广州保瑞医疗技术有限公司 Intravascular laser heating whole body thermal therapy instrument
CN108325089A (en) * 2018-01-03 2018-07-27 南通大学 A kind of tumour laserthermia and multi-parameters real-time monitoring probe
CN109276818A (en) * 2018-11-16 2019-01-29 中聚科技股份有限公司 A kind of laser fiber shield
CN109363931A (en) * 2018-10-25 2019-02-22 潍坊医学院 The temperature control method of optical-fiber laser thermal conductivity acupuncture needle warming device

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101347657B (en) * 2007-07-17 2012-02-01 深圳市蓝韵实业有限公司 Ultrasonic probe fixture mechanism applied to ultrasonic tumor treatment system
CN101757739A (en) * 2008-12-25 2010-06-30 上海复旦张江生物医药股份有限公司 Optical-fiber sleeve tube for vaginas and cervixes
CN104768489A (en) * 2012-11-08 2015-07-08 皇家飞利浦有限公司 Interventional device, method of assembling, and assembling system
US10342510B2 (en) 2012-11-08 2019-07-09 Koninklijke Philips N.V. Interventional device, method of assembling, and assembling system
CN109771030A (en) * 2013-04-30 2019-05-21 临床激光热疗系统公司 Device and method for controlling the laserthermia of immunostimulation
CN105120948A (en) * 2013-04-30 2015-12-02 临床激光热疗系统公司 Apparatus and method for controlling immunostimulating laser thermotherapy
CN105120948B (en) * 2013-04-30 2019-07-09 临床激光热疗系统公司 For controlling the device and computer-readable medium of the laserthermia of immunostimulation
CN106691675A (en) * 2015-07-24 2017-05-24 广州保瑞医疗技术有限公司 Intravascular laser heating whole body thermal therapy instrument
CN105496637B (en) * 2016-01-28 2018-07-13 中国医科大学附属第一医院 A kind of equipment for inducing the anti-cervical human papillomavirus-affected of immunity of organism
CN105496637A (en) * 2016-01-28 2016-04-20 中国医科大学附属第一医院 Equipment for inducing body immunity to resist cervical human papilloma viral infection
CN108325089A (en) * 2018-01-03 2018-07-27 南通大学 A kind of tumour laserthermia and multi-parameters real-time monitoring probe
CN109363931A (en) * 2018-10-25 2019-02-22 潍坊医学院 The temperature control method of optical-fiber laser thermal conductivity acupuncture needle warming device
CN109276818A (en) * 2018-11-16 2019-01-29 中聚科技股份有限公司 A kind of laser fiber shield

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