CN1491652A - Chemical mixture and its use - Google Patents
Chemical mixture and its use Download PDFInfo
- Publication number
- CN1491652A CN1491652A CNA021350299A CN02135029A CN1491652A CN 1491652 A CN1491652 A CN 1491652A CN A021350299 A CNA021350299 A CN A021350299A CN 02135029 A CN02135029 A CN 02135029A CN 1491652 A CN1491652 A CN 1491652A
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- CN
- China
- Prior art keywords
- chemical mixture
- anisodamine
- dexamethasone
- acetaminophen
- pseudoephedrine hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of chemical mixture and its application. The chemical mixture of five components including acetaminophen, ABOB, anisodamine, dexamethasone and pseudoephedrine hydrochloride is used in the medicinal treatment of cold with excellent effect, no bad reaction, and no side effect.
Description
Technical field
The present invention relates to a kind of chemical mixture and application thereof, particularly a kind of chemical mixture and application thereof that can be used for treating flu.
Background technology
Flu is a kind of commonly encountered diseases, and almost everyone lives through the inconvenience that flu is brought.At present in tens kinds of coldrexs of selling on the market, indicate and contain the antihistaminic pharmaceutical compositions, account for about 70%.Contain antihistaminic pharmaceutical compositions (as chlorphenamine etc.) the caused untoward reaction of coldrex-dizziness, drowsiness, trick is aching and limp, myasthenia of limbs, though entail dangers to life not allows the people very uncomfortable also.Because drowsy, be unable to pull oneself together, have a strong impact on work, study, general two to three days ability of this situation is removed, many people fear to take this type of medicine that cures cold.Have the scholar to think: " chlorphenamine does not have therapeutic value to common cold.Its faint cholinolytic effect can reduce runny nose, but this kind desiccation is more harm than good.It causes does not drowsinessly have any benefit yet." (" Drug therapy preferred version " Zhang Annian writes-Chinese Medicine science and technology publishing house in March, 1999 front page the 332nd page).The coldrex of pure Chinese medicine preparation, though there is not the drowsiness untoward reaction of Denging, onset is slow comparatively speaking, and is unsatisfactory.
The purpose of this invention is to provide a kind of chemical mixture, this chemical mixture can be very fast the healing flu, and safety, no untoward reaction such as drowsiness.
Summary of the invention
Chemical mixture provided by the invention is made of by weight percentage following each composition:
Acetaminophen 63.3%-67.3%
Beautiful jade guanidine 26.9%-31.5
Anisodamine 1.0%-1.5%
Dexamethasone 0.2%
Pseudoephedrine hydrochloride 4%
More than the mechanism of action of each composition: acetaminophen can suppress the prostaglandin synthetase of human body, makes that prostaglandin is synthetic to be reduced and produce good antipyretic effect, can treat have a headache and fever, cold symptoms such as limbs pain, myalgia, general malaise.The beautiful jade guanidine is a broad-spectrum antiviral drug, and RNA viruses (first type and Influenza B virus, parainfluenza virus, rhinovirus, respiratory syncytial virus) is all had the obvious suppression effect, is mainly used in and prevents and treats influenza, viral bronchitis etc.Anisodamine is the M cholinoreceptor blocker, can suppress lachrymal gland and respiratory tract glandular secretion, stops the watery nasal discharge that flu causes.Pseudoephedrine hydrochloride is an adrenomimetic, has the upper respiratory tract of contraction blood capillary, eliminates the nasopharynx part mucous hyperemia, alleviates the effect of nasal obstruction symptom.Dexamethasone is long lasting glucocorticosteroid amcinonide, can suppress infectious and non-infectious inflammation, and it is synthetic to reduce the prostaglandin inflammatory mediator, alleviates the telangiectasis of nasopharynx inflam mation tissue and oozes out, and alleviates symptoms such as red, swollen, hot, pain.Can also reduce histamine release, the antagonism bacterial endotoxin is to the irritant reaction of body, and usefulness collaborative and the reinforcement said medicine.
Untoward reaction such as that chemical mixture provided by the invention does not have is drowsiness, myasthenia of limbs, rapid-action, side effect is little, and economical and practical, and treatment time is short.
Embodiment
Embodiment 1: get the chemical mixture that is indication of the present invention after acetaminophen 63.3g, beautiful jade guanidine 26.9g, Anisodamine 1g, dexamethasone 0.2g, pseudoephedrine hydrochloride 4g mix.
Embodiment 2: get the chemical mixture that is indication of the present invention after acetaminophen 67.4g, beautiful jade guanidine 31.5, Anisodamine 1.5g, dexamethasone 0.2g, pseudoephedrine hydrochloride 4g mix.
Embodiment 3: get the chemical mixture that is indication of the present invention after acetaminophen 65g, beautiful jade guanidine 28g, Anisodamine 1.25g, dexamethasone 0.2g, pseudoephedrine hydrochloride 4g mix.
Claims (2)
1, a kind of chemical mixture is characterized in that: this chemical mixture is that five kinds of chemical analysis by following each percentage by weight mix: acetaminophen 63.3%-67.4%, beautiful jade guanidine 26.9%-31.5%, Anisodamine 1.0%-1.5%, dexamethasone 0.2%, pseudoephedrine hydrochloride 4%.
2, the described chemical mixture of claim 1, being applied to treat in the medicine of flu has good result.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135029 CN1208063C (en) | 2002-10-25 | 2002-10-25 | Chemical mixture and its use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135029 CN1208063C (en) | 2002-10-25 | 2002-10-25 | Chemical mixture and its use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1491652A true CN1491652A (en) | 2004-04-28 |
| CN1208063C CN1208063C (en) | 2005-06-29 |
Family
ID=34231420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02135029 Expired - Lifetime CN1208063C (en) | 2002-10-25 | 2002-10-25 | Chemical mixture and its use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1208063C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331485C (en) * | 2005-05-31 | 2007-08-15 | 王鹏程 | Medicine for treating cold |
| CN105412118A (en) * | 2015-12-17 | 2016-03-23 | 侯丽芳 | Western medicinal composition for treating acute or chronic dyspnea and preparation method of western medicinal composition |
-
2002
- 2002-10-25 CN CN 02135029 patent/CN1208063C/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331485C (en) * | 2005-05-31 | 2007-08-15 | 王鹏程 | Medicine for treating cold |
| CN105412118A (en) * | 2015-12-17 | 2016-03-23 | 侯丽芳 | Western medicinal composition for treating acute or chronic dyspnea and preparation method of western medicinal composition |
| WO2017101696A1 (en) * | 2015-12-17 | 2017-06-22 | 侯丽芳 | Western medicine composition for treating acute and chronic dyspnea and preparation method thereof |
| CN105412118B (en) * | 2015-12-17 | 2019-03-22 | 侯丽芳 | Treat dyspneic Western medicine compound of acute and chronic and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1208063C (en) | 2005-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20050629 Effective date of abandoning: 20121226 |
|
| C20 | Patent right or utility model deemed to be abandoned or is abandoned |