CN1208063C - Chemical mixture and its use - Google Patents
Chemical mixture and its use Download PDFInfo
- Publication number
- CN1208063C CN1208063C CN 02135029 CN02135029A CN1208063C CN 1208063 C CN1208063 C CN 1208063C CN 02135029 CN02135029 CN 02135029 CN 02135029 A CN02135029 A CN 02135029A CN 1208063 C CN1208063 C CN 1208063C
- Authority
- CN
- China
- Prior art keywords
- chemical mixture
- pharmaceutical composition
- anisodamine
- moroxydine
- dexamethasone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a chemical mixture and a use thereof. The chemical mixture which is prepared by mixing five ingredients of paracetamol, moroxydine, anisodamine, dexamethasone and pseudoephedrine hydrochloride is applied to the drug treatment of cold to realize the advantages of good effect, no adverse reaction, such as somnolence, myasthenia of limb, etc., rapid effect, small side effect, economy and short treatment time.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly a kind of pharmaceutical composition that can be used for treating flu.
Background technology
Flu is a kind of commonly encountered diseases, and almost everyone lives through the inconvenience that flu is brought.At present in tens kinds of coldrexs of selling on the market, indicate and contain the antihistaminic pharmaceutical compositions, account for about 70%.Contain antihistaminic pharmaceutical compositions (as chlorphenamine etc.) the caused untoward reaction of coldrex-dizziness, drowsiness, trick is aching and limp, myasthenia of limbs, though entail dangers to life not allows the people very uncomfortable also.Because drowsy, be unable to pull oneself together, have a strong impact on work, study, general two to three days ability of this situation is removed, many people fear to take this type of medicine that cures cold.Have the scholar to think: " chlorphenamine does not have therapeutic value to common cold.Its faint cholinolytic effect can reduce runny nose, but this kind desiccation is more harm than good.It causes does not drowsinessly have any benefit yet." (" Drug therapy preferred version " Zhang Annian writes the 332nd page of Chinese Medicine science and technology publishing house in March, 1999 front page).Though the coldrex of pure Chinese medicine preparation does not have the drowsiness untoward reaction of Denging, onset is slow comparatively speaking, and is unsatisfactory.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition, said composition can be very fast the healing flu, and safety, no untoward reaction such as drowsiness.
Pharmaceutical composition provided by the invention is made of by weight percentage following each composition:
Acetaminophen 63.3%-67.4%
Moroxydine 26.9%-31.5%
Anisodamine 1.0%-1.5%
Dexamethasone 0.2%
Pseudoephedrine hydrochloride 4%
More than the mechanism of action of each composition: acetaminophen can suppress the prostaglandin synthetase of human body, makes that prostaglandin is synthetic to be reduced and produce good antipyretic effect, can treat have a headache and fever, cold symptoms such as limbs pain, myalgia, general malaise.Moroxydine is a broad-spectrum antiviral drug, and RNA viruses (first type and Influenza B virus, parainfluenza virus, rhinovirus, respiratory syncytial virus) is all had the obvious suppression effect, is mainly used in and prevents and treats influenza, viral bronchitis etc.Anisodamine is the M cholinoreceptor blocker, can suppress lachrymal gland and respiratory tract glandular secretion, stops the watery nasal discharge that flu causes.Pseudoephedrine hydrochloride is an adrenomimetic, has the upper respiratory tract of contraction blood capillary, eliminates the nasopharynx part mucous hyperemia, alleviates the effect of nasal obstruction symptom.Dexamethasone is long lasting sugared skin parahormone class medicine, can suppress infectious and non-infectious inflammation, and it is synthetic to reduce the prostaglandin inflammatory mediator, alleviates the telangiectasis of nasopharynx inflam mation tissue and oozes out, and alleviates symptoms such as red, swollen, hot, pain.Can also reduce histamine release, the antagonism bacterial endotoxin is to the irritant reaction of body, and usefulness collaborative and the reinforcement said medicine.
Untoward reaction such as that pharmaceutical composition provided by the invention does not have is drowsiness, myasthenia of limbs, rapid-action, side effect is little, and economical and practical, and treatment time is short.
The specific embodiment:
Embodiment 1: get the pharmaceutical composition that is indication of the present invention after acetaminophen 63.3g, Moroxydine 26.9g, Anisodamine 1g, dexamethasone 0.2g, pseudoephedrine hydrochloride 4g mix.
Embodiment 2: get the pharmaceutical composition that is indication of the present invention after acetaminophen 67.4g, Moroxydine 31.5g, Anisodamine 1.5g, dexamethasone 0.2g, pseudoephedrine hydrochloride 4g mix.
Embodiment 3: get the pharmaceutical composition that is indication of the present invention after acetaminophen 65g, Moroxydine 28g, Anisodamine 1.25g, dexamethasone 0.2g, pseudoephedrine hydrochloride 4g mix.
Claims (1)
1. pharmaceutical composition that is used for the treatment of flu is characterized in that: said composition is that five kinds of chemical analysis by following each percentage by weight mix: acetaminophen 63.3%～67.4%, Moroxydine 26.9%～31.5%, Anisodamine 1.0%～1.5%, dexamethasone 0.2%, pseudoephedrine hydrochloride 4%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135029 CN1208063C (en) | 2002-10-25 | 2002-10-25 | Chemical mixture and its use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02135029 CN1208063C (en) | 2002-10-25 | 2002-10-25 | Chemical mixture and its use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1491652A CN1491652A (en) | 2004-04-28 |
| CN1208063C true CN1208063C (en) | 2005-06-29 |
Family
ID=34231420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02135029 Expired - Lifetime CN1208063C (en) | 2002-10-25 | 2002-10-25 | Chemical mixture and its use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1208063C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331485C (en) * | 2005-05-31 | 2007-08-15 | 王鹏程 | Medicine for treating cold |
| CN105412118B (en) * | 2015-12-17 | 2019-03-22 | 侯丽芳 | Treat dyspneic Western medicine compound of acute and chronic and preparation method thereof |
-
2002
- 2002-10-25 CN CN 02135029 patent/CN1208063C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1491652A (en) | 2004-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20050629 Effective date of abandoning: 20121226 |
|
| C20 | Patent right or utility model deemed to be abandoned or is abandoned |