CN1485057A

CN1485057A - Acne-treating composition

Info

Publication number: CN1485057A
Application number: CNA021309655A
Authority: CN
Inventors: 刚姚; 姚刚; 姚桂茹; 姚景海
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-09-23
Filing date: 2002-09-23
Publication date: 2004-03-31
Anticipated expiration: 2022-09-23
Also published as: CN1194727C

Abstract

The invention relates to an externally used composition for treating acne, in the form of powder medicine comprising sulfur, rheum officinale, vermillion, pearl and dried alum, or in the form of liquid containing honeysuckle flower, isatis root, capsule of weeping forsythia, flavescent sophora root and licorice root,

Description

The compositions of treatment acne

Technical field

The present invention relates to treat the topical composition of acne.

Background technology

Acne is commonly called as acne, is the between twenty and fifty normal a kind of chronic hair follicle sebum inflammation of suffering from, and the position vigorous in face, chest, back and smegma is easy to generate.Factors such as it is excessive owing to androgen, smegma is crossed Sheng, the excessive keratinization of follicular wall, endocrine disturbance cause, and more are easy to generate in adolescence, and the women often has outbreak before and after menstruation.

Acne such as untimely treatment may go from bad to worse, and severe patient can form tuberosity, cyst even cicatrix.After acne disappears, also can leave over the little cicatrix of pigmentation or concavity.

The western medical treatment acne mainly adopts the Drug therapy of antibiotic, tretinoin medicines and endocrine regulation, be used for infection, reduce sebum secretion and sebaceous gland duct portion hyperkeratosis, and suppress androgen secretion, but antibiosis usually has side effect.The traditional Chinese medical science thinks that acne is that lung meridian stagnation of pathogenic heat retardance skin forms the main rule of treatment that adopts detoxifcation, invigorates blood circulation.External can make the efficacy of a drug sick institute that goes directly, and heightens the effect of a treatment.

Summary of the invention

The application's purpose just provides a kind of topical composition for the treatment of acne, and it follows the prescription principle of medication of the traditional Chinese medical science, proves through clinical practice, can treat acne effectively.

The base stock of compositions of the present invention is composed as follows:

Acne is loose: sulfur, Radix Et Rhizoma Rhei, Vermilion, Margarita, dried Alumen.

Acne liquid: Flos Lonicerae, Radix Isatidis, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Glycyrrhizae

In prescription, sulfur detoxifcation parasite killing, external is with after skin secretion contacts, and formation sulfide has softening epidermis and infection, antiinflammatory, a fat effect of dispelling.It is antibacterial that Radix Et Rhizoma Rhei has antiinflammatory, improves the merit of blood circulation.Margarita can make skin moist pure white, fine and smooth flexible, can suppress the lipofuscin growth, reduces facial wrinkles.Dried Alumen damp eliminating convergence enhances metabolism and affected part skin crust is early taken off.Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Radix Sophorae Flavescentis and Radix Glycyrrhizae, heat-clearing and toxic substances removing dispels the wind.

By weight, the consumption of each raw material is:

Acne is loose: sulfur, each 1-3 part of Radix Et Rhizoma Rhei, Vermilion, Margarita, each 1-2 part of dried Alumen.Preferable amount is: each 2 parts of sulfur, Radix Et Rhizoma Rhei, respectively 1 part of Vermilion, Margarita, dried Alumen.

Acne liquid: Flos Lonicerae, Radix Isatidis, Fructus Forsythiae, Radix Sophorae Flavescentis, each equal portions of Radix Glycyrrhizae.

More than be the square substantially of compositions, add on this basis invigorate blood circulation, regulate the flow of vital energy, the flavour of a drug of effect such as heat-clearing and toxic substances removing, can strengthen the effect of this compositions, also within the protection domain of this patent.

The preparation of compositions method is: sulfur, Radix Et Rhizoma Rhei, Vermilion, Margarita, dried Alumen are ground into fine flour respectively and cross 20 mesh sieves, and mixing becomes acne and looses, and packing is standby.Flos Lonicerae, Radix Isatidis, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Glycyrrhizae are fine flour altogether, remove slag with 1 week of soaking in rice vinegar of 5-10 times of weight of raw material of Chinese medicine weight and make acne liquid, and it is standby to bottle.Or Flos Lonicerae, Radix Isatidis, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Glycyrrhizae water or 50-95% ethanol extraction (for example decoct, backflow, percolation, merceration, warm macerating) obtain extracting solution, except that after desolvating, be condensed into the thick paste shape, add raw material weight 5-10 rice vinegar doubly and be diluted to suspension, the time spent shakes up.

Directly make behind the also available 5-10 of the acne liquid water extraction doubly; Or behind the ethanol extraction with the 50-95% of 5-10 times of weight, concentrate and remove part ethanol, concentration of ethanol is adjusted to 20-75% and make; But do the effect that solvent can strengthen medicine antiinflammatory convergence, sterilization infiltration, blood circulation promoting and blood stasis dispelling with rice vinegar, so preferred rice vinegar.

Using method: get acne and loose in right amount, place in the container, pour an amount of acne liquid furnishing scattered paste shape into, be acne ointment.Handle is cleaned, and dips in mass with finger and is coated with gently and puts face or other affected parts on the skin, every day respectively 1 time sooner or later, or every day 3 times.Big pimple can be coated on the acne lump with more condensed acne ointment, does the back and moistens with the acne drop.Continuous use can early be healed.

Points for attention: do not apply some make up, can not be with mask, summer anti glare anti static coatings, winter is antifreeze.Note cleaning, dirt is avoided contacting in the affected part.Can not take off after the incrustation, should treat that it comes off naturally.Avoid and drink and hot raw meat stimulating food.

Clinical efficacy is summed up

One. physical data man 11 examples, women 19 examples, age 51-16 year, 7 examples below 20 years old, 20-30 year 16 examples, 7 examples more than 30 years old, the course of disease is the longest 19 years, and is the shortest 90 days, facial area 21 examples are involved neck 6, thoracic dorsal 3 examples.

Two. diagnostic criteria

With reference to the disease of tcm diagnostic criteria in the People's Republic of China's Chinese medicine industry standard that comes into effect January 1 nineteen ninety-five.

Acne is pimple, pustule, nodositas, can extrude the white sample powder juice of cracking rice sometimes.From the beginning of at follicular orifice, be the red pimple of grain of rice size, also can develop into pustule, after this can form scleroma sample hoary hair's acne or blackhead, severe patient can form scleroma property cyst.Normal companion's seborrhea.

Three. curative effect determinate standard

Curing skin lesion disappears.

Take a turn for the better: skin lesion disappears more than 30%.

Do not heal: skin lesion disappear less than 30% or no change.

Four. administrated method and points for attention are as mentioned above

Five. therapeutic outcome:

The initial stage part of applying ointment is rubescent, and skin has and kills pain slightly, and affected part is little itches, and pimple increases, and the reinfection of adding is seemingly arranged, and symptom fades away after 3-5 days, and incrustation comes off then.Along with crust come off pimple from large to small, fade away, it is normal that skin color recovers, continue to be coated with acne ointment this moment, the elasticity and the gloss of skin are better.

Treat 30 examples, cure rate 100%

Above presentation of results this method treatment acne, method is easy, instant effect, good effect.Embrocate medicine with finger, can promote cutaneous circulation, medicine is easily absorbed, can quicken shallow table inflammation and disappear, the softening skin horny layer promotes seborrheic plug to discharge, and regulates smegma.

Claims

1. a powder composite for the treatment of acne is made by following materials of weight proportions: sulfur, each 1-3 part of Radix Et Rhizoma Rhei, Vermilion, Margarita, each 1-2 part of dried Alumen.

2. compositions according to claim 1 is characterized in that described proportion of raw materials is: each 2 parts of sulfur, Radix Et Rhizoma Rhei, respectively 1 part of Vermilion, Margarita, dried Alumen.

3. compositions for the treatment of acne, make by following materials of weight proportions:: Flos Lonicerae, Radix Isatidis, Fructus Forsythiae, Radix Sophorae Flavescentis, each equal portions of Radix Glycyrrhizae.

4. the described method for compositions of preparation claim 3 is characterized in that may further comprise the steps: use the soaking in rice vinegar raw material of 5-10 times of weight of raw material weight, remove slag and make.

5. the described method for compositions of preparation claim 3 is characterized in that may further comprise the steps: with raw material water or 50-95% ethanol extraction, obtain extracting solution, except that after desolvating, be condensed into the thick paste shape, add raw material weight 5-10 rice vinegar doubly and be diluted to suspension.

6. the described method for compositions of preparation claim 3 is characterized in that with making behind the raw material weight 5-10 water extraction raw material doubly.

7. preparation claim 3 described method for compositions, it is characterized in that ethanol extraction raw material with the 50-95% of 5-10 times of weight of raw material weight after, concentrate and remove part ethanol, or add entry, concentration of ethanol adjusted to 20-75% and make.