Background technology
As everyone knows, since ancient times, people have just invented wine brewing, because wine sweet-smelling delicious food, be subjected to people's favor deeply, become and drink good merchantable brand, but wine is to decompose every ml ethanol in the intravital unique useful value of people, can produce 5.6 kilocalories heat, it can not be in vivo synthesized or is stored as saccharide or fat, need eliminating external, except a spot of ethanol can be from pulmonary, outside perspiration and kidney were got rid of, major part was to be undertaken excreting after Oxidation is decomposed by liver, by a large amount of discovering, ethanol is divided into following several steps substantially at the intravital oxidation decomposition course of people:
The first step is that a kind of alcohol dehydrogenase of hepatic secretion is transformed into acetaldehyde with ethanol, and discharges 2 hydrogen atoms, if insobriety, the acetaldehyde accumulation too much intoxicating phenomenon will occur, for example, dizziness, headache, vomiting, amblygeustia and dry mouth and tougue, and cause symptom such as be still drank after a night.
Second step was the ferment of a kind of aldehyde dehydrogenase of hepatic secretion, and the further oxidation Decomposition of acetaldehyde is become acetic acid.
The 3rd step was that the further in vivo oxidation Decomposition of acetic acid becomes carbon dioxide and water.
In order to reduce the injury of drinking health and liver being caused, developed beverages such as Antialcoholic tea, the soup of sobering up at present, but its curative effect is more not remarkable, the injury that health and liver are caused that can not overcome that excessive consumption of alcohol causes.
Summary of the invention
The purpose of this invention is to provide a kind of relieving alcoholism and protecting the liver liquid product and production method thereof,, reach the purpose of effective relieving alcoholism and protecting the liver by with comprehensive vegetables and fruits fermenation raw liquid, chitin poly oligosaccharide stock solution and rice vinegar combination.
The object of the present invention is achieved like this: a kind of relieving alcoholism and protecting the liver liquid product, it is characterized in that: it mainly comprises following compositions in portion by weight composition: comprehensive vegetables and fruits fermenation raw liquid 40-70 part, chitin poly oligosaccharide stock solution 10-30 part and rice vinegar 10-30 part, this comprehensive vegetables and fruits fermenation raw liquid and chitin poly oligosaccharide fermenation raw liquid are respectively multiple vegetables and fruits and chitosan to be cultivated by probiotic bacteria and yeast inoculation fermentation, produce the fermenation raw liquid and the chitin poly oligosaccharide fermenation raw liquid of comprehensive vegetables and fruits.
These vegetables and fruits comprise by Fructus Lycopersici esculenti, Fructus Cucurbitae moschatae, Rhizoma Dioscoreae, the cattle, square-bottomed bamboo basket fore-telling, cabbage, Fructus Cucumidis sativi, Fructus Chaenomelis, Fructus Ananadis comosi, Fructus Armeniacae Mume, Fructus Citri Limoniae, Aloe or Radix Et Caulis Acanthopanacis Senticosi recklessly.The content of this probiotic bacteria is the 0.02-5 parts by weight, and this probiotic bacteria is selected from one of the following or its combination: acetic acid bacteria, cereuisiae fermentum, excellent lactobacillus or Bacillus natto.
The present invention also provides a kind of production method of relieving alcoholism and protecting the liver liquid product, it is characterized in that: it comprises the steps:
(1) fermenation raw liquid of the single vegetables and fruits of preparation: choose single vegetables and fruits raw material, through washing, dry and cutting into slices; Get single vegetables and fruits raw material 100 parts by weight, add yeast 0.01-0.5 parts by weight and sucrose 15-25 parts by weight mix homogeneously; Room temperature standing for fermentation 2-5 days, restir is even, carries out sufficient fermentation culture 3-6 time so repeatedly; Left standstill 20-90 days, and after treating fully to ferment,, prepared the fermenation raw liquid of single vegetables and fruits by the centrifuge coarse filtration;
(2) fermenation raw liquid of the comprehensive vegetables and fruits of preparation: the fermenation raw liquid of choosing the single vegetables and fruits of at least three kinds of different cultivars vegetables and fruits is allocated 100 parts by weight as required; Add yeast 0.01-0.5 parts by weight mix homogeneously subsequently; Room temperature left standstill 20-90 days, carried out sufficient fermentation culture; After treating fully fermentation, carry out finly filtration, prepare the fermenation raw liquid (viable bacteria) of comprehensive vegetables and fruits by Filter column;
(3) preparation chitin poly oligosaccharide fermenation raw liquid: with 100 parts of chitosans, sucrose 150-200 part, distilled water 4000-8000 part and yeast 0.5-8.0 part mix homogeneously, put into fermentation tank room temperature and cultivated 15-30 days, carry out sufficient fermentation culture; After treating fully fermentation, carry out finly filtration,, prepare chitin poly oligosaccharide fermenation raw liquid again in 100 ℃ of scaldings by Filter column;
(4) preparation rice vinegar: brown rice is boiled postcooling; Choose 100 parts in brown rice and meter Qu 0.5-1.0 part mix homogeneously carried out saccharifying 1-3 days according to following parts by weight proportioning; Add distilled water 120-200 part and yeast 0.05-1.0 part mix homogeneously, put into fermentation tank room temperature 20-90 days, carry out sufficient fermentation culture; After treating fully fermentation, carry out finly filtration, prepare rice vinegar by centrifuge coarse filtration and Filter column;
(5) preparation relieving alcoholism and protecting the liver liquid product:, carry out finly filtration by centrifuge coarse filtration and Filter column with comprehensive vegetables and fruits fermenation raw liquid 40-70%, chitin poly oligosaccharide stock solution 10-30% and rice vinegar 10-30% mix homogeneously; Through check and packing, produce relieving alcoholism and protecting the liver liquid product of the present invention again.
It also comprises adding probiotic bacteria 0.02-5 parts by weight, and this probiotic bacteria is selected from one of the following or its combination: acetic acid bacteria, cereuisiae fermentum, excellent lactobacillus or Bacillus natto.It is that comprehensive vegetables and fruits fermenation raw liquid 62 parts by weight, chitin poly oligosaccharide stock solution 15 parts by weight, rice vinegar 20 parts by weight and the combination of cereuisiae fermentum 3 parts by weight are made.It is that comprehensive vegetables and fruits fermenation raw liquid 65 parts by weight, chitin poly oligosaccharide stock solution 20 parts by weight, rice vinegar 12.5 parts by weight and the combination of acetic acid bacteria 2.5 parts by weight are made.
Further specify below in conjunction with preferred embodiment and accompanying drawing.
The specific embodiment
Embodiment 1
The trade name of relieving alcoholism and protecting the liver liquid product of the present invention is " 597 board livers must happy oral liquid ", and it is that comprehensive vegetables and fruits fermenation raw liquid 60 parts by weight chitin poly oligosaccharide stock solution 20 parts by weight and the combination of rice vinegar 20 parts by weight are made.Through test, the main nutrient composition in the 50ml oral liquid is chitin poly oligosaccharide 3-4 gram, saponin 1-3 gram, flavone 0.5-1.5 gram and polysaccharide 2-3.5 gram.
The production method of relieving alcoholism and protecting the liver liquid product of the present invention comprises: production, the production of chitin poly oligosaccharide fermenation raw liquid, the production of rice vinegar and the production of the liver protecting liquid product that relieves the effect of alcohol of the production of the fermenation raw liquid of single vegetables and fruits, comprehensive vegetables and fruits fermenation raw liquid (viable bacteria).Below state the production method of relieving alcoholism and protecting the liver liquid product of the present invention respectively.
Consult shown in Figure 1, the production method of the fermenation raw liquid of single vegetables and fruits of the present invention is with multiple vegetables and fruits, comprise by Fructus Lycopersici esculenti, Fructus Cucurbitae moschatae, Rhizoma Dioscoreae, the cattle, square-bottomed bamboo basket fore-telling, cabbage, Fructus Cucumidis sativi, Fructus Chaenomelis, Fructus Ananadis comosi, Fructus Armeniacae Mume, Fructus Citri Limoniae, Aloe or Radix Et Caulis Acanthopanacis Senticosi etc. recklessly, cultivate by the yeast inoculation fermentation respectively, produce the fermenation raw liquid of single vegetables and fruits.Concrete steps comprise:
At first choose single vegetables and fruits raw material, through washing, dry and cutting into slices; Get single vegetables and fruits raw material 100 parts by weight, add yeast 0.3 parts by weight and sucrose 21 parts by weight mix homogeneously; Room temperature standing for fermentation 2-5 days, restir is even, carries out sufficient fermentation culture 5 times so repeatedly; After treating fully fermentation,, produce the fermenation raw liquid of single vegetables and fruits by the centrifuge coarse filtration.
Consult shown in Figure 2ly, the production method of the fermenation raw liquid of comprehensive vegetables and fruits of the present invention is that the fermenation raw liquid of multiple single vegetables and fruits is cultivated by the yeast inoculation fermentation, produces comprehensive vegetables and fruits fermenation raw liquid of the present invention (viable bacteria).Concrete steps comprise:
The fermenation raw liquid of at first choosing the single vegetables and fruits of five kinds of different cultivars vegetables and fruits is deployed into 100 parts as required, for example Fructus Chaenomelis fermenation raw liquid 40 parts by weight, Rhizoma Dioscoreae fermenation raw liquid 20 parts by weight, Fructus Cucumidis sativi fermenation raw liquid 15 parts by weight, Fructus Ananadis comosi fermenation raw liquid 15 parts by weight and fermented tomato stock solution 10 parts by weight; Add yeast 0.01-0.5 parts by weight mix homogeneously subsequently; Room temperature left standstill 80 days, carried out sufficient fermentation culture; After treating fully fermentation, carry out finly filtration, produce the fermenation raw liquid (viable bacteria) of comprehensive vegetables and fruits by Filter column.
Consult shown in Figure 3ly, the production method of chitin poly oligosaccharide fermenation raw liquid of the present invention is that chitosan and sucrose are cultivated by the yeast inoculation fermentation, produces chitin poly oligosaccharide fermenation raw liquid of the present invention.Concrete steps comprise:
At first choose raw material according to following weight proportion: 100 parts of chitosans, 180 parts of sucrose, 5000 parts of distilled water and 7 parts of mix homogeneously of yeast, put into fermentation tank room temperature and cultivated 20 days, carry out sufficient fermentation culture; After treating fully fermentation, carry out finly filtration,, produce chitin poly oligosaccharide fermenation raw liquid of the present invention again in 100 ℃ of scaldings by Filter column.
Consult shown in Figure 4ly, the production method of rice vinegar of the present invention is that brown rice is mixed with a rice Qu, by yeast inoculation fermentation cultivation, produces rice vinegar of the present invention.Concrete steps comprise:
At first brown rice is boiled postcooling; Choose 100 parts in brown rice and 0.6 part of mix homogeneously of meter Qu carried out saccharifying 1-3 days according to following parts by weight proportioning; Add 150 parts of distilled water and 0.6 part of mix homogeneously of yeast, put into fermentation tank room temperature 85 days, carry out sufficient fermentation culture; After treating fully fermentation, carry out finly filtration, produce rice vinegar of the present invention by centrifuge coarse filtration and Filter column.
Consult shown in Figure 5ly, the collocation method of relieving alcoholism and protecting the liver liquid product of the present invention is that comprehensive vegetables and fruits fermenation raw liquid 60 parts by weight, chitin poly oligosaccharide stock solution 20 parts by weight and the combination of rice vinegar 20 parts by weight are made.Concrete steps comprise:
At first be with comprehensive vegetables and fruits fermenation raw liquid 60 parts by weight, chitin poly oligosaccharide stock solution 20 parts by weight and rice vinegar 20 parts by weight mix homogeneously, carry out finly filtration by Filter column; Through check and packing, produce relieving alcoholism and protecting the liver liquid product of the present invention again.
Embodiment 2
Also comprise in the production method of the relieving alcoholism and protecting the liver liquid product of the embodiment of the invention 2 adding probiotic bacteria 0.02-5 parts by weight, this probiotic bacteria is selected from one of the following or its combination: acetic acid bacteria, cereuisiae fermentum, excellent lactobacillus or Bacillus natto.Certainly, probiotic bacteria can add when fermentation, or adds when the configuration of relieving alcoholism and protecting the liver liquid product.
Its production method is with embodiment 1, so do not repeat.
Embodiment 3
The relieving alcoholism and protecting the liver liquid product of the embodiment of the invention is that comprehensive vegetables and fruits fermenation raw liquid 55 parts by weight chitin poly oligosaccharide stock solution 20 parts by weight and the combination of rice vinegar 25 parts by weight are made.
Its production method is with embodiment 1, so do not repeat.
Embodiment 4
The relieving alcoholism and protecting the liver liquid product of the embodiment of the invention 4 is that comprehensive vegetables and fruits fermenation raw liquid 62 parts by weight chitin poly oligosaccharide stock solutions 15 parts by weight, rice vinegar 20 parts by weight and the combination of cereuisiae fermentum 3 parts by weight are made.
Its production method is with embodiment 1, so do not repeat.
Embodiment 5
The relieving alcoholism and protecting the liver liquid product of the embodiment of the invention 5 is that comprehensive vegetables and fruits fermenation raw liquid 65 parts by weight chitin poly oligosaccharide stock solutions 20 parts by weight, rice vinegar 12.5 parts by weight and the combination of acetic acid bacteria 2.5 parts by weight are made.
Its production method is with embodiment 1, so do not repeat.
The main effect of relieving alcoholism and protecting the liver liquid product of the present invention is as follows:
1, the acetic acid bacteria in the probiotic bacteria that comprises of relieving alcoholism and protecting the liver liquid product of the present invention can be secreted ferment such as abundant alcohol dehydrogenase and aldehyde dehydrogenase, after duodenum absorbs, can in gastrointestinal and blood, take the lead in ethanol is resolved into acetic acid, greatly alleviate the work of liver decomposing alcohol, can effectively reduce the generation of alcoholic hepatitis, fatty liver and liver cirrhosis, and overcome the acetaldehyde intoxicating phenomenon;
2; relieving alcoholism and protecting the liver liquid product of the present invention has the effect of whole the intestines and stomach; because wine is drunk in the tripe; a part is absorbed by stomach; most of by duodenum and jejunum absorption; drink and destroy the interior flora ecological balance of gastrointestinal tract; probiotics such as bacillus bifidus and excellent lactobacillus are reduced; and harmful bacterium such as staphylococcus and pseudomonas are increased; cause appetite depression; diarrhoea or constipation; relieving alcoholism and protecting the liver liquid product of the present invention is to adopt the human body beneficial bacterium to ferment at normal temperatures; contain a large amount of digestive enzyme; metabolic enzyme and oligosaccharide; make probiotics such as bacillus bifidus and excellent lactobacillus propagation; therefore, drink preceding or drink after drink the effect that relieving alcoholism and protecting the liver liquid product of the present invention has protection gastrointestinal and propagation digestive system beneficial flora.
3, relieving alcoholism and protecting the liver liquid product of the present invention contains the about 2-3.5 gram of polysaccharide in the 50ml oral liquid, by high-effect liquid chromatography (LC) instrument (HPLC) or the test of photodiode block form detector, polysaccharide has the immunocyte of promotion hypertrophy ability, regulates the T cell function and promotes the active effect of phagocyte.
4, relieving alcoholism and protecting the liver liquid product of the present invention contains the chitin poly oligosaccharide of the 3-4 gram of having an appointment in the 50ml oral liquid, by high-effect liquid chromatography (LC) instrument (HPLC) or the test of photodiode block form detector, the chitin poly oligosaccharide has the immunocyte hypertrophy ability of promotion and antibody generates, promote the natural killer cytoactive and promote the phagocyte activity, and regulate the T cell function.
5, relieving alcoholism and protecting the liver liquid product of the present invention contains the about 1-3 gram of saponin in the 50ml oral liquid, and saponin has blood fat reducing, blood pressure lowering and liver-protective effect.
6, relieving alcoholism and protecting the liver liquid product of the present invention contains the about 0.5-1.5 gram of flavone in the 50ml oral liquid, and flavone has the effect of blood fat reducing and blood pressure lowering.
7, relieving alcoholism and protecting the liver liquid product of the present invention, detect by high-effect liquid chromatography (LC) instrument (HPLC) or enzymatic activity, contain alcohol dehydrogenase and aldehyde dehydrogenase, it has efficient antialcoholic effect, can reduce the influence of ethanol, and significantly reduce the probability that acute pancreatitis takes place nervus centralis.
8, relieving alcoholism and protecting the liver liquid product of the present invention detects by thalline separation detection and enzyme number, contains Bacillus natto, bacillus bifidus and lactobacillus, and it is the probiotic bacteria of large intestine, has the effect that improves function of intestinal canal.
9, learn by analysis, in the relieving alcoholism and protecting the liver liquid product of the present invention, also contain multiple pepsin, can alleviate the secretion and the burden of gastric juice, and improve the adverse current symptom of gastric acid significantly.