CN1470299A - Transducer array for high-intersity focusing ultrasonic tumor treatment - Google Patents

Transducer array for high-intersity focusing ultrasonic tumor treatment Download PDF

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Publication number
CN1470299A
CN1470299A CNA031294073A CN03129407A CN1470299A CN 1470299 A CN1470299 A CN 1470299A CN A031294073 A CNA031294073 A CN A031294073A CN 03129407 A CN03129407 A CN 03129407A CN 1470299 A CN1470299 A CN 1470299A
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transducer array
piezoelectric ceramic
power amplifier
matching layer
ceramic piece
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CNA031294073A
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CN1281286C (en
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寿文德
钱德初
沈祺茂
耿晓鸣
石珍龙
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WUXI HAIYING ELECTRONIC MEDICAL SYSTEMS Inc
Shanghai Jiaotong University
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WUXI HAIYING ELECTRONIC MEDICAL SYSTEMS Inc
Shanghai Jiaotong University
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Publication of CN1470299A publication Critical patent/CN1470299A/en
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Abstract

The invention is a kind of transverter array in high-intensity focusing supersonic tumour treat. The invention is made up of matching layer and piezoelectricity chinaware pieces. The matching layer is a even bowl sound radiating layer, all the piezoelectricity chinaware pieces are stuck on the outer surface of the same matching layer, the piezoelectricity forms the transverter array. The invention has a high focusing sound-intensity ratio and sound speaking feature; the cost is low; the structure is simple, and the stability and the reliability are enhanced.

Description

High-intensity focus supersonic tumor treatment transducer array
Technical field
What the present invention relates to is a kind of transducer array, and transducer array is used in particularly a kind of high-intensity focus supersonic tumor treatment, belongs to field of medical.
Background technology
Ultrasonic transducer or transducer array are the core components of high-intensity focus supersonic tumor therapy system.It can convert electric energy to ultrasonic energy and be focused on, and forms high-intensity focal zone or focal spot, produces high temperature in target tissue (tumor), kills cancerous cell.The quality of its performance is directly connected to therapeutic effect, safety and reliability, has very important meaning.Common HIFU focused transducer system is divided into unit transducer and multielement transducer array two classes.The unit transducer has two kinds of lens-type and curved surface self focusing-types.The former realizes focusing on large aperture plane disc piezoelectric ceramic transducer and solid acoustic lens combination, but the efficient of acoustic lens is difficult to improve.The latter focuses on large aperture concave spherical surface bowl-type piezoelectric ceramic transducer, for guaranteeing to have very big focusing acoustic ratio, to improve the safety and the effectiveness of treatment, requires to make large aperture recessed ball shell shape piezo ceramic element, is difficult on the technology realize.
The multielement transducer array can be installed in a large aperture rigidity by many unit focused transducers (normally circular) and focus on the spherical surface body and constitute, and forms confocal some configuration.Two kinds of Discrete Distribution and continuous distribution are arranged.The former focusing performance is relatively poor, and the energy concentration degree is lower.The latter requires unit transducer yardstick little, and array element number is many, could realize good focusing performance.But also performance, installation accuracy, the concordance of multichannel power amplifier, the stability to array element has proposed strict requirement, and the complexity of debugging and maintenance increases severely, and the reliability of system is brought many adverse effects.Technical difficulty is big, and hidden danger is many, the cost height.
Find by literature search, Zhang Dejun is at " national ultrasonic medical engineering academic meeting paper collection in 2000 " 11-18 page or leaf (in December, 2000, Chongqing) " high-intensity focusing ultrasonic transducer " literary composition of delivering on, this article has been introduced: the recessed Shell Transducer in unit, the structure of dull and stereotyped wafer adventitious sound lens type transducer and multielement transducer array and sound field thereof are calculated.Non-phased focused array is difficult to reach desirable focal spot if array number and corresponding port number are few.And the recessed Shell Transducer in unit, after Ultrasonic-B probe was installed at the center of dull and stereotyped wafer adventitious sound lens type transducer, maximum sound pressure obviously descended, and vertically focal spot elongates and degenerates.Obviously emission area can obviously reduce, and acoustical power reduces.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, a kind of high-intensity focus supersonic tumor treatment transducer array is provided, it can be satisfied forms and the similar sound field characteristic requirement of large aperture focused transducer, overcome the required concave spherical surface shell piezo ceramic element of unit, large aperture transducer and be difficult to make difficulty, can make transducer array element quantity unlikely too many again, avoided a large amount of array elements to inlay constituting problems such as concordance that concave spherical surface focused transducer array brings, stability, complexity, very high reliability and P/C ratio has been arranged on engineering.
The present invention is achieved by the following technical solutions, the present invention is made up of matching layer and piezoelectric ceramic piece, matching layer is the acoustic radiation layer of the uniform large aperture of a thickness recessed ball shell bowl-type, all piezoelectric ceramic pieces are glued on the outer surface of same matching layer, and a plurality of identical piezoelectric ceramic pieces constitute a large aperture tight mosaic transducer array of concave spherical surface altogether.
The piezoelectric ceramic piece distribution of whole energy transducer array is meridian and evenly cuts apart the billiard table shape, the radius of curvature of its inner surface equals the radius of curvature of matching layer outer surface, closely be spliced to form complete successive common focused radiation face, the radius of curvature of each piezoelectric ceramic piece, thickness, shape size are identical, perforate in the middle of the matching layer is for the installation position of location Ultrasonic-B probe is provided.
All piezoelectric ceramic pieces are glued on the outer surface of same matching layer, to form a common uniform concave ball shape radiating surface (matching layer inner surface), have guaranteed that radiated sound field reaches goodish symmetry and good focus characteristics.
Transducer array is provided with the electric drive part, and electric drive partly comprises: frequency synthesizer, adjustable phase shifter, power amplifier, matching network.Its connected mode is: the frequency synthesizer outfan is connected with the adjustable phase shifter input, the adjustable phase shifter outfan is connected with the power amplifier input, the power amplifier outfan is connected with matching network, and the matching network outfan is connected with piezoelectric ceramic piece by radio-frequency cable.Each piezoelectric ceramic piece array element is all driven through matching network by separately power amplifier, each road power amplifier all by same signal generator (being frequency synthesizer) through the phase shifter excitation, identical with the ultrasonic operating frequency that guarantees emission.By regulating phase shift, ultrasonic that each piezoelectric ceramic piece sends superposeed at focus place same phase.The thickness of acoustic radiation matching layer is the integral multiple of 1/2nd wavelength, makes its resonance under ultrasonic operating frequency, obtains higher transducer electroacoustic efficiency.All be furnished with phase shifter circuit before each power amplifier, the scalable phase place guarantees output same phase acoustic pressure.
The present invention has substantive distinguishing features and marked improvement, and the present invention can be the very big curve focusing transducer array with continuous radiation face, has very high battle array and focuses on acoustic ratio and symmetric well focussed sound field characteristic; The piezoelectric ceramic piece area of each array element is less, low cost of manufacture; Array element number, power amplifier number of active lanes are few, so the concordance of power amplifier, phase shifter and matching network more easily realizes, makes, adjusts all simpler, and stability and reliability greatly improve; Common matching layer provides the firm support of transducer array element, and can also strengthen the concordance of each array element resonance with resonance takes place in array element, makes the output acoustic power of array reach maximum.
Description of drawings
Fig. 1 structural representation of the present invention
The structural representation of the hexa-atomic transducer array of Fig. 2
The electric drive part-structure figure of the hexa-atomic transducer array of Fig. 3
The specific embodiment
As Fig. 1, Fig. 2 and shown in Figure 3, the present invention is made up of matching layer 1 and piezoelectric ceramic piece 2, matching layer 1 is the acoustic radiation layer of a uniform recessed ball shell bowl-type of thickness, all piezoelectric ceramic pieces 2 are glued on the outer surface of same matching layer 1, and a plurality of identical piezoelectric ceramic pieces 2 constitute a large aperture tight mosaic transducer array 3 of concave spherical surface altogether.
The piezoelectric ceramic piece 2 of whole energy transducer array 3 distributes and is the billiard table shape that meridian is evenly cut apart, the radius of curvature of its inner surface equals the radius of curvature of matching layer outer surface, closely be spliced to form complete successive common focused radiation face, the radius of curvature of each piezoelectric ceramic piece 2, thickness, shape size are identical, have approaching resonant frequency.
Transducer array 3 is provided with electric drive part 4, electric drive part 4 comprises: frequency synthesizer 5, adjustable phase shifter 6, power amplifier 7, matching network 8, its connected mode is: frequency synthesizer 5 outfans are connected with adjustable phase shifter 6 inputs, adjustable phase shifter 6 outfans are connected with power amplifier 7 inputs, power amplifier 7 outfans are connected with matching network 8, matching network 8 outfans are connected with piezoelectric ceramic piece 2 by radio-frequency cable, each piezoelectric ceramic piece 2 is all driven through matching network 8 by separately power amplifier 7, each road power amplifier 7 is all by 5 excitations of same frequency synthesizer, all is furnished with adjustable phase shifter 6, control phase before each power amplifier 7.
Perforate in the middle of the matching layer 1, the thickness of matching layer 1 is the integral multiple of 1/2nd wavelength.

Claims (4)

1, a kind of high-intensity focus supersonic tumor treatment transducer array, it is characterized in that, form by matching layer (1) and piezoelectric ceramic piece (2), matching layer (1) is the acoustic radiation layer of a uniform recessed ball shell bowl-type of thickness, all piezoelectric ceramic pieces (2) are glued on the outer surface of same matching layer (1), and a plurality of identical piezoelectric ceramic pieces (2) constitute a large aperture tight mosaic transducer array of concave spherical surface (3) altogether.
2, high-intensity focus supersonic tumor treatment transducer array according to claim 1, it is characterized in that, the piezoelectric ceramic piece (2) of whole energy transducer array (3) distributes and is the billiard table shape that meridian is evenly cut apart, the radius of curvature of its inner surface equals the radius of curvature of matching layer outer surface, closely be spliced to form complete successive common focused radiation face, the radius of curvature of each piezoelectric ceramic piece (2), thickness, shape size are identical, have very approaching resonant frequency.
3, high-intensity focus supersonic tumor treatment transducer array according to claim 1 and 2, it is characterized in that, transducer array (3) is provided with electric drive part (4), electric drive part (4) comprising: frequency synthesizer (5), adjustable phase shifter (6), power amplifier (7), matching network (8), its connected mode is: frequency synthesizer (5) outfan is connected with adjustable phase shifter (6) input, adjustable phase shifter (6) outfan is connected with power amplifier (7) input, power amplifier (7) outfan is connected with matching network (8), matching network (8) outfan is connected with piezoelectric ceramic piece (2) by radio-frequency cable, each piezoelectric ceramic piece (2) is all driven through matching network (8) by separately power amplifier (7), each road power amplifier (7) is all encouraged by same frequency synthesizer (5), each power amplifier (7) is preceding all is furnished with adjustable phase shifter (6), control phase.
4, transducer array is used in high-intensity focus supersonic tumor treatment according to claim 1, it is characterized in that, and perforate in the middle of the matching layer (1), the thickness of matching layer (1) is the integral multiple of 1/2nd wavelength.
CN 03129407 2003-06-19 2003-06-19 Transducer array for high-intersity focusing ultrasonic tumor treatment Expired - Lifetime CN1281286C (en)

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006069467A1 (en) 2004-12-27 2006-07-06 Ninglei Lai Quasi-self focusing high intensity and large power ultrasonic transducer
CN100446827C (en) * 2005-05-19 2008-12-31 上海交通大学 Self focusing array ultrasonic energy changer
CN100584278C (en) * 2007-11-30 2010-01-27 深圳市蓝韵实业有限公司 Device for testing the compatibility of front end amplification channel of ultrasonic diagnostic device
CN101190436B (en) * 2006-11-22 2010-09-29 中国科学院声学研究所 Phase control focusing ultrasound wave source device
WO2012094850A1 (en) * 2011-01-14 2012-07-19 深圳市普罗惠仁医学科技有限公司 Ultrasonic focusing transducer
CN108259011A (en) * 2016-12-29 2018-07-06 中国科学院深圳先进技术研究院 A kind of power amplification system of phased array High Intensity Focused Ultrasound equipment
CN108339727A (en) * 2017-01-23 2018-07-31 中国科学院声学研究所 A kind of high frequency dualbeam directional transducer and preparation method thereof
CN109433570A (en) * 2019-01-07 2019-03-08 中国科学院声学研究所北海研究站 A kind of polyhedron spherical transducer and preparation method thereof
CN111012318A (en) * 2020-01-18 2020-04-17 四川知周光声医疗科技有限公司 Surface focusing array detector and system for photoacoustic breast imaging
CN111151432A (en) * 2020-01-20 2020-05-15 重庆医科大学 Variable-thickness focusing ultrasonic transducer and transduction system for compressing axial length of acoustic focal region and method for determining axial length of acoustic focal region
CN111347221A (en) * 2020-03-09 2020-06-30 中科绿谷(深圳)医疗科技有限公司 Manufacturing process of ultrasonic transducer and ultrasonic transducer
CN115475746A (en) * 2022-09-27 2022-12-16 南京海克医疗设备有限公司 Frequency conversion stacking annular self-gathering ultrasonic transducer
CN115624690A (en) * 2022-10-14 2023-01-20 江苏省声学产业技术创新中心 Bowl-shaped piezoelectric ceramic structure for transdermal drug delivery instrument and application thereof

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US8181523B2 (en) * 2008-07-22 2012-05-22 Nuovo Pignone S.P.A. Ultrasound inspection methods for noisy cast materials and related probes

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7602672B2 (en) 2004-12-27 2009-10-13 Ninglei Lai Quasi-self focusing high intensity and large power ultrasonic transducer
WO2006069467A1 (en) 2004-12-27 2006-07-06 Ninglei Lai Quasi-self focusing high intensity and large power ultrasonic transducer
CN100446827C (en) * 2005-05-19 2008-12-31 上海交通大学 Self focusing array ultrasonic energy changer
CN101190436B (en) * 2006-11-22 2010-09-29 中国科学院声学研究所 Phase control focusing ultrasound wave source device
CN100584278C (en) * 2007-11-30 2010-01-27 深圳市蓝韵实业有限公司 Device for testing the compatibility of front end amplification channel of ultrasonic diagnostic device
WO2012094850A1 (en) * 2011-01-14 2012-07-19 深圳市普罗惠仁医学科技有限公司 Ultrasonic focusing transducer
CN108259011A (en) * 2016-12-29 2018-07-06 中国科学院深圳先进技术研究院 A kind of power amplification system of phased array High Intensity Focused Ultrasound equipment
CN108339727B (en) * 2017-01-23 2020-02-18 中国科学院声学研究所 High-frequency dual-beam directional transducer and manufacturing method thereof
CN108339727A (en) * 2017-01-23 2018-07-31 中国科学院声学研究所 A kind of high frequency dualbeam directional transducer and preparation method thereof
CN109433570A (en) * 2019-01-07 2019-03-08 中国科学院声学研究所北海研究站 A kind of polyhedron spherical transducer and preparation method thereof
CN109433570B (en) * 2019-01-07 2023-06-16 中国科学院声学研究所北海研究站 Polyhedral spherical transducer and manufacturing method thereof
CN111012318A (en) * 2020-01-18 2020-04-17 四川知周光声医疗科技有限公司 Surface focusing array detector and system for photoacoustic breast imaging
CN111151432A (en) * 2020-01-20 2020-05-15 重庆医科大学 Variable-thickness focusing ultrasonic transducer and transduction system for compressing axial length of acoustic focal region and method for determining axial length of acoustic focal region
CN111347221A (en) * 2020-03-09 2020-06-30 中科绿谷(深圳)医疗科技有限公司 Manufacturing process of ultrasonic transducer and ultrasonic transducer
CN111347221B (en) * 2020-03-09 2021-08-27 中科绿谷(深圳)医疗科技有限公司 Manufacturing process of ultrasonic transducer and ultrasonic transducer
CN115475746A (en) * 2022-09-27 2022-12-16 南京海克医疗设备有限公司 Frequency conversion stacking annular self-gathering ultrasonic transducer
CN115624690A (en) * 2022-10-14 2023-01-20 江苏省声学产业技术创新中心 Bowl-shaped piezoelectric ceramic structure for transdermal drug delivery instrument and application thereof
CN115624690B (en) * 2022-10-14 2023-10-31 江苏省声学产业技术创新中心 Bowl-shaped piezoelectric ceramic structure for transdermal drug delivery instrument and application thereof

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