CN1562411A - Phase control focusing ultrasonic transducer array in high internsity - Google Patents
Phase control focusing ultrasonic transducer array in high internsity Download PDFInfo
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- CN1562411A CN1562411A CN 200410017185 CN200410017185A CN1562411A CN 1562411 A CN1562411 A CN 1562411A CN 200410017185 CN200410017185 CN 200410017185 CN 200410017185 A CN200410017185 A CN 200410017185A CN 1562411 A CN1562411 A CN 1562411A
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Abstract
A high-intensity ultrasonic transducer array which phase-conrol fucusing is composed of a big-aperture rigid spherical crown body with a geometric radium close to maximal scan depth, a centrol hole for installing the probe of ultrasonography B and several small holes distributed in the mode of multi-layer regular ring array with unequal spacings, and several array cells inlaid in said holes. Its advantages are correct location, flexible focusing, small array aperture, and high grating lobe suppressing power and sonic intensity gain.
Description
Technical field
The present invention relates to a kind of phase-control focusing high intensity ultrasound transducer array, be applied to high intensity focused ultrasound (HIFU) system of tumor treatment, belong to the biomedical engineering technology field.
Background technology
High-intensity focusing ultrasonic transducer is one of critical component of high-intensity focus supersonic tumor therapy system.It not only will infiltrate through tissue at the ultrasonic energy of external emission, and form a zone that the sound intensity is high---Jiao Qu by certain type of focusing in target tissue.Burnt district is interior owing to energy deposits in a large number, make the tissue transient temperature that is positioned at wherein up to more than 65 ℃, the moment coagulation necrosis appears in this portion of tissue thereupon, and the tissue outside the Jiao Qu is injury-free substantially because of only there being less energy to deposit, thereby reaches the purpose that targeting destroys pathological changes.
The type of focusing of existing high-intensity focusing ultrasonic transducer mainly contains: curved surface self-focusing, sound lens focusing and phased array focus on.
The operation principle of curved surface self-focusing is analogous to the optics concave mirror focus, and the operation principle of sound lens focusing then is analogous to the optics concavees lens and focuses on.They generally can only form position, the fixed single focus of intensity, are difficult to correct location and scanning, and operation flexibility is poor.
The operation principle that phased array focuses on is different fully with them, no longer be to utilize reflection characteristic or the refracting characteristic of ultrasound wave in transmission course, but by controlling the phase place of array element pumping signal, sound wave wave surface curvature and center are changed, thereby realize the electron focusing and the scanning of acoustic beam.
United States Patent (USP) the 4th, 865, disclosed a kind of phase-control focusing high intensity ultrasound transducer array for No. 042, it is a kind of spherical crown transducer array, include a plurality of concentric rings on the curved surface that place, these concentric rings have equal surface area, and are divided into the transducer unit of many bendings---array element along circumference.These array elements are identical by frequency, but the phase place high frequency electrical signal different with amplitude encourages.The phase place and the amplitude of the corresponding pumping signal of correct control, array will focus on the radiating ultrasonic energy of each array element in the desirable burnt district, and reach and be enough to make target tissue the energy level of moment coagulation necrosis to occur.This class phase-control focusing high intensity ultrasound transducer array has overcome the shortcoming of curved surface self-focusing, sound lens focusing ultrasonic transducer basically, but not only operation flexibility is limited for it, and the sidelobe level of ultrasonic beam is higher, may form one even several focal zones, cause unexpected heating, the harm patient.
Summary of the invention
The objective of the invention is to above-mentioned deficiency at prior art, design provides a kind of phase-control focusing high intensity ultrasound transducer array, can proofread and correct or compensate focusing and the position error that causes because of various factors by electronic-controlled mode, realize focusing on flexible, accurate positioning.
For realizing such purpose, the phase-control focusing high intensity ultrasound transducer array of the present invention's design adopts a kind of sphere, rule, unequal-interval ring battle array structure, mainly comprise a large aperture rigidity ball-crown body, ultrasonic transducer unit---the array element of several Discrete Distribution.
The spherical crown geometric radius of large aperture rigidity ball-crown body levels off to the maximum scan degree of depth, promptly focuses on minimum-depth and axial scan scope sum, and array element quantity and diameter thereof are depended in the spherical crown aperture.The central openings of ball-crown body provides installing space for the location Ultrasonic-B probe.Be distributed with several circular apertures on the whole ball-crown body discretely, inlay an array element in each aperture, the slightly larger in diameter of aperture is in the diameter of array element, the regularity of distribution of array element is a multilamellar rule unequal-interval ring battle array, be that interval between each circular layer has nothing in common with each other, every layer has the array element of same number and is evenly distributed, wherein first array element on the odd number circular layer all is positioned on the Y-axis, and the equal clockwise direction of first array element on the even number circular layer departs from the same angle of Y-axis, and the axis of each array element and the axes intersect of ball-crown body are in focus.Any three adjacent array elements all are scalene triangle arranges, and the ternary array of being made up of them has constituted the minimum array of phase-control focusing.
Array element of the present invention adopts circular, plane form, and the diameter of each array element, thickness are all identical, can be made by the PZT-8 piezoelectric ceramics, and its outer surface gummed has matching layer.Array element critically is embedded in respectively in the aperture of ball-crown body, is aided with the binding agent gummed simultaneously.Each array element all has independently electric excitation signal feeder line, is connected to the phased signal excitation system respectively.
The electric excitation signal of each array element of the present invention all is independent controlled, the phase place that the phase place of adjusting electric excitation signal has also just been regulated the array element surface vibration velocity, make the wave surface of the radiating sound wave of all array element behind spatial coherence form sphere and assemble or deflection, thereby realized electronically controlled focus ultrasonic and scanning.
Phase-control focusing high intensity ultrasound transducer array of the present invention has characteristics such as sphere, rule, unequal-interval simultaneously concurrently, therefore has strong graing lobe and suppresses ability, high sound intensity gain and little advantages such as array aperture.Can realize electron focusing and scanning, make treatment accurate positioning, flexible, switch the focal position fast; The type of focusing is flexible, can form different focus intensity and distribution pattern according to different pathological tissues shape and positions, not only can form single focus but also can form many focuses; Beam path control can make acoustic beam walk around barriers such as skeleton, thereby avoid ultrasonic damage to normal structure flexibly; Can proofread and correct or compensate focusing and the position error that causes because of factors such as the difference of inhomogeneities, the transducer performance of tissue and therapeutic goal move by electronic-controlled mode.Novel structure compactness of the present invention, selection is common, function admirable, multiple functional, work has broad application prospects flexibly.
Description of drawings
Fig. 1 is a structure side view of the present invention.
Among Fig. 1,1 is large aperture rigidity ball-crown body, and 2 is array element, and 3 is the central openings of ball-crown body---location Ultrasonic-B probe installing space, 4 is the electric excitation signal feeder line.
Fig. 2 is an array element distribution schematic diagram of the present invention.
Among Fig. 2,1 is large aperture rigidity ball-crown body, and 2 is array element, and 3 is the central openings of ball-crown body.
The specific embodiment
In order to understand technical scheme of the present invention better, be described in further detail below in conjunction with accompanying drawing.
The structure side view of the phase-control focusing high intensity ultrasound transducer array of the present invention's design as shown in Figure 1.The central openings 3 of large aperture rigidity ball-crown body 1 is location Ultrasonic-B probe installing space, and the multilamellar circular aperture that distributes discretely on the ball-crown body outside the central openings 31 is inlayed array element 2 in the aperture.The spherical crown geometric radius R of ball-crown body 1 levels off to the maximum scan degree of depth, promptly focuses on minimum-depth and axial scan scope sum.Each array element 2 all has independently electric excitation signal feeder line, is connected to the phased signal excitation system respectively.
Fig. 2 is an array element distribution schematic diagram of the present invention.As shown in Figure 2, the present invention adopts a kind of sphere, rule, unequal-interval ring battle array structure, mainly comprise a large aperture rigidity ball-crown body 1, the ultrasonic transducer unit of N Discrete Distribution---array element 2, the central openings 3 of ball-crown body 1 is location Ultrasonic-B probe installing space.Around central openings 3, on ball-crown body 1, be distributed with N circular aperture discretely, inlay an array element 2 in each aperture, the slightly larger in diameter of aperture is in the diameter of array element 2.Array element 2 is that regular multilamellar unequal-interval ring battle array distributes, and promptly N array element is divided into A, B, and C, D ... Deng M circular layer, the interval between each circular layer has nothing in common with each other.Every layer of array element that same number (N/M) arranged is evenly distributed.Wherein, A, C ... Deng first array element on the odd number circular layer (A01, C01 ...) all be positioned on the Y-axis, and B, D ... Deng first array element on the even number circular layer (B01, D01 ...) all depart from identical angle [alpha] of Y-axis in the direction of the clock.The axes intersect of the axis of each array element 2 and ball-crown body 1 is in focus.Any three adjacent array elements all are scalene triangle arranges, and the ternary array of being made up of them has constituted the minimum array of phase-control focusing.Array element quantity N and array element diameter are depended in the aperture of ball-crown body 1.
In one embodiment of the invention, the spherical crown geometric radius R of large aperture rigidity ball-crown body 1 is 20cm, level off to the maximum scan degree of depth, promptly focus on minimum-depth D1 (16cm) and axial scan scope D3 (4cm) sum, the aperture of ball-crown body 1 is 174mm, the quantity N=90 of array element 2, array element diameter are 14mm.The central openings 3 of ball-crown body (φ 50mm) provides installing space for the location Ultrasonic-B probe.Be distributed with 90 circular apertures on the ball-crown body 1 discretely, inlay array element 2 in the aperture.The regularity of distribution of array element 2 is a multilamellar rule unequal-interval ring battle array, and promptly 90 array elements are divided into A, B, and C, D, E, F is M=6 circular layer altogether, and the interval between each layer has nothing in common with each other.Every layer has N/M=15 array element to be evenly distributed.A, C, first array element on the odd number circular layers such as E (A01, C01 E01) all are positioned on the Y-axis, and B, D, (F01) all clockwise direction departs from 12 ° of Y-axis to first array element on the even number circular layers such as F for B01, D01.Each array element axis and spherical crown axes intersect are in focus O.Any three adjacent array elements all are scalene triangle arranges, and the ternary array of being made up of them has constituted the minimum array of phase-control focusing.
In an embodiment of the present invention, optimized choice has been made in the selection of each parts, guaranteeing not only function admirable of phase-control focusing high intensity ultrasound transducer array, and relative low price.Large aperture rigidity ball-crown body 1 adopts poly-tetrafluoro alkene, ultrasonic transducer unit---array element 2 adopts circular, plane form, the diameter d of each array element 2 (14mm), thickness h (4mm) are all identical, are all made by the PZT-8 piezoelectric ceramics, and its outer surface gummed has matching layer.Array element 2 critically is embedded in respectively in all apertures of ball-crown body, is aided with the binding agent gummed simultaneously.Each array element all has independently electric excitation signal feeder line 4, is connected to the phased signal excitation system respectively.
The present invention has characteristics such as sphere, rule, unequal-interval simultaneously concurrently, and therefore, it has strong graing lobe and suppresses ability, high sound intensity gain and little advantages such as array aperture.
Claims (2)
1. phase-control focusing high intensity ultrasound transducer array, it is characterized in that forming by a large aperture rigidity ball-crown body (1) and several array element (2), the central openings (3) of ball-crown body (1) is location Ultrasonic-B probe installing space, the spherical crown geometric radius of ball-crown body (1) levels off to the maximum scan degree of depth, center on the circular aperture that distributes discretely on the ball-crown body (1) of central openings (3), inlay an array element (2) in each aperture, array element (2) is that multilamellar rule unequal-interval ring battle array distributes, interval between each circular layer has nothing in common with each other, every layer has the array element (2) of same number and is evenly distributed, wherein first array element on the odd number circular layer all is positioned on the Y-axis, the equal clockwise direction of first array element on the even number circular layer departs from the same angle of Y-axis, the axes intersect of axis of each array element (2) and ball-crown body (1) is in focus, any three adjacent array elements (2) all are scalene triangle and arrange, the ternary array of being made up of them constitutes the minimum array of phase-control focusing, each array element (2) all has independently electric excitation signal feeder line, is connected to the phased signal excitation system respectively.
2. phase-control focusing high intensity ultrasound transducer array as claimed in claim 1 is characterized in that described array element (2) adopts circular, plane form, and diameter, the thickness of each array element are identical.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200410017185A CN100586508C (en) | 2004-03-25 | 2004-03-25 | Phase control focusing ultrasonic transducer array with high intensity |
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| CN200410017185A CN100586508C (en) | 2004-03-25 | 2004-03-25 | Phase control focusing ultrasonic transducer array with high intensity |
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| CN1562411A true CN1562411A (en) | 2005-01-12 |
| CN100586508C CN100586508C (en) | 2010-02-03 |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100446827C (en) * | 2005-05-19 | 2008-12-31 | 上海交通大学 | Self focusing array ultrasonic energy changer |
| CN102319485A (en) * | 2011-08-19 | 2012-01-18 | 陈明 | Focus positioning treatment device and system thereof |
| CN102430211A (en) * | 2011-08-19 | 2012-05-02 | 陈明 | X-ray location-based focusing therapy unit and system |
| WO2012094850A1 (en) * | 2011-01-14 | 2012-07-19 | 深圳市普罗惠仁医学科技有限公司 | Ultrasonic focusing transducer |
| CN101810913B (en) * | 2009-02-25 | 2013-03-27 | 西门子公司 | Ultrasonic transducer |
| CN104013444A (en) * | 2014-06-23 | 2014-09-03 | 南京广慈医疗科技有限公司 | Phased array high-intensity focused ultrasonic ablation system |
| CN107999363A (en) * | 2016-10-28 | 2018-05-08 | 钟志刚 | The automatically controlled vibrating device of three coordinates |
| CN105823827B (en) * | 2016-05-27 | 2018-07-17 | 中国矿业大学 | A kind of supersonic array combined type roll-setting gear |
| CN109044403A (en) * | 2018-08-31 | 2018-12-21 | 重庆医科大学 | The excitation of digital control type low-strength focusing ultrasonic wave and imaging system |
-
2004
- 2004-03-25 CN CN200410017185A patent/CN100586508C/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100446827C (en) * | 2005-05-19 | 2008-12-31 | 上海交通大学 | Self focusing array ultrasonic energy changer |
| CN101810913B (en) * | 2009-02-25 | 2013-03-27 | 西门子公司 | Ultrasonic transducer |
| WO2012094850A1 (en) * | 2011-01-14 | 2012-07-19 | 深圳市普罗惠仁医学科技有限公司 | Ultrasonic focusing transducer |
| CN102319485A (en) * | 2011-08-19 | 2012-01-18 | 陈明 | Focus positioning treatment device and system thereof |
| CN102430211A (en) * | 2011-08-19 | 2012-05-02 | 陈明 | X-ray location-based focusing therapy unit and system |
| CN102319485B (en) * | 2011-08-19 | 2014-05-14 | 陈明 | Focus positioning treatment device and system thereof |
| CN104013444A (en) * | 2014-06-23 | 2014-09-03 | 南京广慈医疗科技有限公司 | Phased array high-intensity focused ultrasonic ablation system |
| CN105823827B (en) * | 2016-05-27 | 2018-07-17 | 中国矿业大学 | A kind of supersonic array combined type roll-setting gear |
| CN107999363A (en) * | 2016-10-28 | 2018-05-08 | 钟志刚 | The automatically controlled vibrating device of three coordinates |
| CN109044403A (en) * | 2018-08-31 | 2018-12-21 | 重庆医科大学 | The excitation of digital control type low-strength focusing ultrasonic wave and imaging system |
| CN109044403B (en) * | 2018-08-31 | 2021-03-16 | 重庆医科大学 | Numerical control type low-intensity focused ultrasonic excitation and imaging system |
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| Publication number | Publication date |
|---|---|
| CN100586508C (en) | 2010-02-03 |
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Granted publication date: 20100203 Termination date: 20130325 |