CN1444652A - 哺乳动物受体蛋白;相关试剂和方法 - Google Patents

哺乳动物受体蛋白;相关试剂和方法 Download PDF

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Publication number
CN1444652A
CN1444652A CN01813327A CN01813327A CN1444652A CN 1444652 A CN1444652 A CN 1444652A CN 01813327 A CN01813327 A CN 01813327A CN 01813327 A CN01813327 A CN 01813327A CN 1444652 A CN1444652 A CN 1444652A
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China
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gly
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Pending
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CN01813327A
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English (en)
Chinese (zh)
Inventor
D·M·戈尔曼
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Merck Sharp and Dohme LLC
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Schering Corp
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Publication of CN1444652A publication Critical patent/CN1444652A/zh
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN01813327A 2000-05-24 2001-05-23 哺乳动物受体蛋白;相关试剂和方法 Pending CN1444652A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20686200P 2000-05-24 2000-05-24
US60/206,862 2000-05-24

Publications (1)

Publication Number Publication Date
CN1444652A true CN1444652A (zh) 2003-09-24

Family

ID=22768279

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01813327A Pending CN1444652A (zh) 2000-05-24 2001-05-23 哺乳动物受体蛋白;相关试剂和方法

Country Status (8)

Country Link
US (2) US20030092881A1 (enExample)
EP (1) EP1303604A2 (enExample)
JP (1) JP2003534013A (enExample)
CN (1) CN1444652A (enExample)
AU (1) AU2001274920A1 (enExample)
CA (1) CA2410083A1 (enExample)
MX (1) MXPA02011617A (enExample)
WO (1) WO2001090358A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106794194A (zh) * 2014-06-30 2017-05-31 中央研究院 用于癌症治疗的介白素‑17受体b(il‑17rb)及其配体il‑17b之拮抗剂

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US7771719B1 (en) 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
CA2328496C (en) 1998-05-15 2016-01-05 Genentech, Inc. Il-17 homologous polypeptides and therapeutic uses thereof
US20040043397A1 (en) 2000-01-11 2004-03-04 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
DK1897944T3 (da) * 1999-12-23 2011-10-24 Genentech Inc IL-17 homologe polypeptider og terapeutisk anvendelse deraf
US7094566B2 (en) 2000-03-16 2006-08-22 Amgen Inc., IL-17 receptor like molecules and uses thereof
AR028256A1 (es) * 2000-03-16 2003-04-30 Amgen Inc Moleculas similares a receptores il-17 y usos de las mismas
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2002004519A2 (en) * 2000-07-06 2002-01-17 Zymogenetics, Inc. Murine cytokine receptor
EP1529843A3 (en) * 2000-08-11 2005-06-08 Eli Lilly & Company Novel secreted proteins and their uses
WO2002038764A2 (en) * 2000-11-10 2002-05-16 The Regents Of The University Of California Il-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage
EP2383278A1 (en) * 2002-07-08 2011-11-02 Genentech, Inc. Method to determine B cell mediated diseases
US20060281146A1 (en) * 2002-09-11 2006-12-14 Genetech, Inc. Novel compositions and methods for the treatment of immune related diseases
AU2004259638C1 (en) 2003-07-08 2018-12-20 Novartis Pharma Ag IL-17 A/F heterologous polypeptides and therapeutic uses thereof
BRPI0511952A (pt) * 2004-06-10 2008-01-29 Zymogenetics Inc receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos de reduzir inflamação induzida por il-17a ou induzida por il-17f, de tratar um mamìfero afetado com uma doença inflamatória, e uma condição patológica em um indivìduo associada com atividade de zcytor14
US20060142192A1 (en) * 2004-10-18 2006-06-29 Zeren Gao Soluble ZcytoR21, anti-ZcytoR21 antibodies and binding partners and methods of using in inflammation
US20060147945A1 (en) * 2005-01-06 2006-07-06 Edmonds Brian T Novel secreted proteins and their uses
US20070249533A1 (en) 2005-09-28 2007-10-25 Levin Steven D Il-17a and il-17f antagonists and methods of using the same
DK1931697T3 (da) * 2005-09-28 2010-11-08 Zymogenetics Inc IL-17A og IL-17F-antagonister og fremgangsmåder til anvendelse af disse
US7622116B2 (en) * 2006-02-10 2009-11-24 Zymogenetics, Inc. Method of treating inflammation using soluble IL-17RCX4
US7790676B2 (en) 2007-03-28 2010-09-07 Zymogenetics, Inc. Soluble IL-17RA/RC fusion proteins
SG10201608871XA (en) 2008-05-05 2016-12-29 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
CA2759848C (en) 2009-05-05 2018-12-04 Novimmune S.A. Anti-il-17f antibodies and methods of use thereof
US9611295B2 (en) * 2011-10-27 2017-04-04 The Cleveland Clinic Foundation Treatment of IL-17 mediated disease by blocking SEFIR-SEFIR interactions
WO2014126902A1 (en) * 2013-02-15 2014-08-21 Thomas Jefferson University Kit for tumor imaging
EP4193154A4 (en) * 2020-08-07 2024-10-02 Athos Therapeutics, Inc. EX VIVO GASTROINTESTINAL BIOPSY PLATFORM FOR EVALUATION OF MULTI-OMICS SIGNATURES FOR SCREENING OF CANDIDATE THERAPEUTIC PRODUCTS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ306653A (en) * 1995-03-23 1999-03-29 Immunex Corp Isolated dna il-17 receptors
US6635443B1 (en) * 1997-09-17 2003-10-21 Human Genome Sciences, Inc. Polynucleotides encoding a novel interleukin receptor termed interleukin-17 receptor-like protein
CA2327317A1 (en) * 1998-04-29 1999-11-04 Genesis Research And Development Corporation Limited Polynucleotides isolated from skin cells and methods for their use
US6150502A (en) * 1998-04-29 2000-11-21 Genesis Research & Development Corporation Limited Polypeptides expressed in skin cells
ATE444361T1 (de) * 1999-12-23 2009-10-15 Genentech Inc Il-17 und il-17r homologe polypeptide und deren therapeutische verwendungen
AR028256A1 (es) * 2000-03-16 2003-04-30 Amgen Inc Moleculas similares a receptores il-17 y usos de las mismas
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106794194A (zh) * 2014-06-30 2017-05-31 中央研究院 用于癌症治疗的介白素‑17受体b(il‑17rb)及其配体il‑17b之拮抗剂

Also Published As

Publication number Publication date
EP1303604A2 (en) 2003-04-23
WO2001090358A3 (en) 2003-01-23
JP2003534013A (ja) 2003-11-18
AU2001274920A1 (en) 2001-12-03
US20030092881A1 (en) 2003-05-15
US20050009145A1 (en) 2005-01-13
WO2001090358A2 (en) 2001-11-29
MXPA02011617A (es) 2003-03-10
CA2410083A1 (en) 2001-11-29

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