CN1440815A

CN1440815A - Ingredient and production process of Chinese medicinal digestive tract contrast medium

Info

Publication number: CN1440815A
Application number: CN 02110088
Authority: CN
Inventors: 王磊; 亓克; 张荣新
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-02-27
Filing date: 2002-02-27
Publication date: 2003-09-10

Abstract

During the production process of Chinese medicinal digestive tract contrast medium, aetite is calcined at 960 deg.c in a furnace to red, cooled slightly and mixed with vinegar, cooled and crushed to 300 mesh; the crushed aetite is mixed with crushed oyster, ark shell, cuttlebone, adhesive, essence and perfume in certain proportion; and the mixture is sterilized, weighed and packed as the contrast medium. The present invention is used in X ray and CT radiography of digestive tract. In addition, the present invention has also the functions of treating gastrointestinal ulcer, gastric cavity pain, gastrointestinal tract bleeding and other diseases.

Description

Chinese medicine gastrointestinal image agent prescription and production method thereof

The present invention relates to Chinese medicine gastrointestinal image agent prescription and production method thereof.

Hacebar has been checked disease usefulness as esophagus, gastrointestinal X line double contrast radiograph in countries in the world hospital so far always since 1901 come out.Barium sulfate is used for the gastroenteropathy diagnosis and uses because its molecular crystal bond structure is tight, and it can form satisfied X line gastrointestinal tract decay pattern picture as contrast agent.From the physiology angle, barium sulfate is a kind of foreign bodies in digestive tract for digestive tract, and is unhelpful also harmless to digestive tract.In clinical, often find the constipated disease of Middle Age and Aged Patients because of doing to cause middle-aged and elderly people when barium meal X line double contrast radiograph is checked.In addition, when patient suffered from serious gastroenteropathy, the doctor was because of being afraid of that using barium sulfate to carry out X line fluoroscopic examination brings harm to patient, so abandon using X line double contrast radiograph inspection technology, causes the state of an illness to fail to pinpoint a disease in diagnosis or mistaken diagnosis.

The purpose of this invention is to provide a kind of barium sulfate that can substitute as X line double contrast radiograph diagnosis usefulness, Chinese medicine gastrointestinal image agent prescription and the production method thereof again can the various gastroenteropathys of auxiliary treatment used.Medicine called after " agent of Chinese medicine gastrointestinal image ".Accomplish that can substitute traditional barium sulfate uses as X line double contrast radiograph, CT contrast agent, again can the various gastroenteropathys of auxiliary treatment.

Prescription of the present invention and content (%) are by one bag of 200g.

MUSYUSHI (Limonitum) 20～40; Concha Arcae 15～20;

Concha Ostreae 15～30; The tip 10～19 wafts in the sea;

Auxiliary material 8～20; Edible essence 0.5～1.0;

Adhesive 0.5～1.0;

Production method of the present invention is as follows:

1, at first Limonitum (MUSYUSHI) is put in the electric furnace (or other heating furnace), heat temperature raising to 960 ℃, constant temperature to Limonitum is popular in, take out the back and place 5～10 fens kinds, tablet vinegar (comprising rice vinegar etc.) is added and stir, natural drying (or heating air-dry), pulverizing and whole mistake 300 mesh sieves are stand-by.

2, it is stand-by Concha Arcae to be pulverized 300 mesh sieves;

3, waftd in Concha Ostreae, sea that to cross 300 mesh sieves stand-by for tip pulverize separately;

4, it is stand-by adhesive (comprising Pseudobulbus Bletillae (Rhizoma Bletillae) and water extract thereof, methylcellulose, seaweed gel etc.) to be pulverized 1000 mesh sieves.

5, will cross the Limonitum 20g of 300 mesh sieves, Concha Arcae 60g, Concha Ostreae 40g, the sea tip 38g that wafts, auxiliary material 40g, adhesive (crossing 1000 mesh sieves) 1.0g, edible essence 1.0g joins one to be mixed in the agitator tank, fully mixing, sterilization, and pack or bottling, jar (adding a certain amount of water in proportion) get final product.

Diseases such as compare with traditional barium sulfate X line double contrast radiograph agent, maximum characteristics of the present invention are not only alternative barium sulfate as X line, CT gastrointestinal tract contrast medium usefulness, and obtain the good diagnostic effect, can treat gastrointestinal ulceration simultaneously, and are hemorrhage.Inorganic elementss such as the calcium among the present invention, strontium, zinc can improve the immunocompetence of human body, strengthen health.

Clinical practice: because this product had both met the requirement of gastrointestinal image agent, have certain pharmacological action again, do the gastrointestinal image agent except that being used to clinically, also can be used for diseases such as auxiliary treatment gastroenteritic ulcer, gastrointestinal hemorrhage, gastrointestinal pain.

The present invention is through acute toxicity test, Salmonella reversion test, and micronucleus test, sperm malformation test, the mouse testis chromosomal aberration test proves to have no adverse reaction.

Embodiment 1: production method as mentioned above, just the prescription of a drug amount is:

MUSYUSHI 20g; Concha Arcae 60g; Concha Ostreae 40g; Tip 38g wafts in the sea; Auxiliary material 40g; Edible essence 1.0g; Adhesive 1.0g.

Embodiment 2: production method as mentioned above, just the prescription of a dose is:

MUSYUSHI 20g; Concha Arcae 50g; Concha Ostreae 50g; Tip 42g wafts in the sea; Auxiliary material 36g; Edible essence 1.0g; Adhesive 1.0g.

Embodiment 3: production method as mentioned above, just the prescription of a drug amount is:

MUSYUSHI 20g; Concha Arcae 70g; Concha Ostreae 40g; Tip 38g wafts in the sea; Auxiliary material 30g; Edible essence 1.0g; Adhesive 1.0g.

Claims

1, the production method of Chinese medicine gastrointestinal image agent is characterized in that production stage is as follows:

A, at first Limonitum (MUSYUSHI) is put in the electric furnace (or other heating furnace), heat temperature raising to 960 ℃, constant temperature to Limonitum is popular in, taking out the back placed 5-10 minute, tablet vinegar (comprising rice vinegar etc.) is added and stir, natural drying (or heating air-dry), pulverizing and whole mistake 300 mesh sieves are stand-by.

B, Concha Arcae, Concha Ostreae, sea waftd to pulverize 300 mesh sieves stand-by for tip etc.;

C, that adhesive (comprising Pseudobulbus Bletillae (Rhizoma Bletillae), seaweed gel, methylcellulose etc.) was pulverized 1000 mesh sieves was stand-by;

D, with the waft tip and cross the adhesive, edible essence (essence that comprises Fructus Mali pumilae, Fructus Fragariae Ananssae, coffee and fruit flavouring) of 1000 mesh sieves ratio mixing, sterilization, pack or bottling, jar (adding a certain amount of water in proportion) of commercially available auxiliary material and Limonitum, Concha Arcae, Concha Ostreae, the sea of pulverizing 300 mesh sieves by the prescription requirement.

2, be used for X line, the agent of CT scan gastrointestinal image according to what the described production method of claim 1 made, it is characterized in that the prescription and the content (%) of a drug amount:

Concoct back Limonitum 20～40; Concha Arcae 15～20;

Concha Ostreae 15～30; The tip 10～19 wafts in the sea;

Auxiliary material 8～20; Edible essence 0.5～1.0;

Adhesive 0.5～1.0.