CN1439268A - Solid stable chlorinedioxide antiseptics and preparation thereof - Google Patents
Solid stable chlorinedioxide antiseptics and preparation thereof Download PDFInfo
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- CN1439268A CN1439268A CN 03121406 CN03121406A CN1439268A CN 1439268 A CN1439268 A CN 1439268A CN 03121406 CN03121406 CN 03121406 CN 03121406 A CN03121406 A CN 03121406A CN 1439268 A CN1439268 A CN 1439268A
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Abstract
A stable solid ClO2 disinfectant is prepared from sodium chlorite, solid acid, composite coating agent and composite trigger through compounding and passivating. Its advantages are high stability and safety, and long storage period.
Description
Technical Field
The invention belongs to the technical field of antibacterial disinfectants, and relates to an improved production method of a chlorine dioxide disinfectant.
Background
Chlorine dioxide is an excellent high-efficiency, broad-spectrum, nontoxic and residue-free disinfectant, and has been widely researched and applied worldwide in recent years because it does not generate carcinogenic, Kazaki and mutagenic effects,
at present, the process for producing the solid chlorine dioxide releasing agent mostly adopts an acidification sodium chlorite method, and the sodium chlorite is easy to react with the solid acidifying agent and immediately releases chlorine dioxide, so the currently used chlorine dioxide disinfectant mostly packages the sodium chlorite and the solid acidifying agent separately, and the binary package is complicated to operate in use.
Chinese patent CN1104610A discloses a method for producing stable chlorine dioxide, which comprises melting white wax or stearic acid or beeswax as coating agent, adding sodium chlorite to preparemicrocapsule particles, mixing with dry tartaric acid or oxalic acid particles, and bagging.
Chinese patent CN1238130A discloses a powdered chlorine dioxide disinfectant and its preparation method, the disinfectant prepared by the production method is packed in one unit, it uses chloride of alkali metal or alkaline earth metal as passivating agent, and plays a role of coating and drying, and before using, sodium chlorite and solid acid do not react, and its disadvantages are that a large amount of drying agent is used as passivating agent in the course of making said disinfectant, so that it has high ineffective component, and because the water absorption of the used passivating agent is strong, the storage time of the disinfectant is short, and especially when the bag is opened, it can quickly lose its effect.
Disclosure of Invention
The invention aims to solve the technical problem of overcoming the stability problem of the chlorine dioxide disinfectant, thereby providing a stable solid which is safer, more effective and more convenient to use, and providing a production method of the disinfectant.
The invention is realized by the following technical scheme:
the disinfectant of the invention adopts an organic polymer coating isolation process to coat sodium chlorite to prepare a coating matrix, then uses anhydrous magnesium sulfate and calcium chloride to further passivate and protect the coating matrix, and then is mixed with a composite activator consisting of solid acid and trichloroisocyanuric acid, thereby effectively realizing the isolation and passivation of materials, avoiding reaction in a packaging bag and achieving the purpose of safety and stability of the disinfectant. When in use, the chlorine dioxide can be released only by dissolving the chlorine dioxide in water, and the principle is that the coating matrix is quickly dissolved and reacts under an acidic condition to decompose part of the chlorine dioxide. At the same time, trichloroisocyanuric acid is hydrolyzed under the acidic condition to release hypochlorous acid (3 mol hypochlorous acid is generated by hydrolyzing 1mol sodium trichloroisocyanurates), and the high-activity hypochlorous acid accelerates the decomposition of sodium chlorite, further improves the yield of chlorine dioxide and generates synergistic effect.
The reaction principle is as follows: the sodium chlorite aqueous solution generates oxidation-reduction reaction (1) in an acid environment, and simultaneously generates effects (2) and (3) for accelerating the oxidation-reduction reaction of the sodium chlorite under the action of the trichloroisocyanuric acid sodium, thereby achieving the aim of generating high-purity chlorine dioxide. When the product generates chlorine dioxide by a very small amount of sodium chlorite autoxidation reaction in the long-term storage process, the chlorine dioxide is absorbed by sodium percarbonate to form sodium chlorite (4), thereby achieving the effect of product stabilization.
A solid stable chlorine dioxide disinfectant consists of sodium chlorite, solid acid and a coating agent, wherein the coating agent consists of polyvinyl alcohol, polyvinylpyrrolidone, cobalt chloride and water, and the components in parts by weight are as follows: 30-50 parts of polyvinyl alcohol, 10-20 parts of polyvinylpyrrolidone, 5-10 parts of cobalt chloride and 30-55 parts of water, 19-27 parts of sodium chlorite and 1-3 parts of sodium percarbonate are mixed, and then a coating agent is coated on the surfaces of the sodium chlorite and the sodium percarbonate to prepare the disinfectant consisting of a coating matrix.
The solid stable chlorine dioxide disinfectant is characterized in that a passivating agent is added into the disinfectant, the passivating agent is composed of magnesium sulfate and calcium chloride, and the components are as follows by weight: 5-10 parts of magnesium sulfate and 5-10 parts of calcium chloride.
The solid stable chlorine dioxide disinfectant is characterized in that a compound excitant is added into the disinfectant, the compound excitant is composed of trichloroisocyanuric acid and citric acid or sulfamic acid, and the components are as follows by weight: 5-15 parts of trichloroisocyanuric acid and 30-50 parts of citric acid or sulfamic acid.
The preparation method of the solid stable chlorine dioxide disinfectant is characterized by comprising the following steps:
a. uniformly mixing polyvinyl alcohol, polyvinylpyrrolidone, cobalt chloride and water according to a ratio to prepare the composite coating agent, wherein the composite coating agent comprises the following components in parts by weight: 30-50% of polyvinyl alcohol, 10-20% of polyvinylpyrrolidone, 5-10% of cobalt chloride and 30-55% of water;
b. putting sodium chlorite and sodium percarbonate into a mixer, continuously spraying a composite coating agent, stirring and mixing, and drying the coated particles to obtain a coating matrix;
c. crushing trichloroisocyanuric acid into powder of 200-400 meshes, and uniformly mixing with citric acid or sulfamic acid to prepare a composite excitant;
d. respectively pulverizing magnesium sulfate and calcium chloride, sieving, drying, mixing with the coated matrix, adding compound activator, mixing, and packaging.
The preparation process effectively realizes material isolation and passivation, so that the sodium chlorite and the compound activator are directly mixed into a bag for packaging, and when the chlorine dioxide composite activator is used, the bag of product is unsealed and directly poured into water to form a chlorine dioxide aqueous solution which is diluted to the required concentration.
Compared with the prior art, the method has the remarkable advantages that ① uses organic polymer as a composite coating agent to coat sodium chlorite to prepare a coating parent body, the coating parent body is further passivated and protected, and then is mixed with a composite exciting agent consisting of solid acid and trichloroisocyanuric acid to effectively realize material isolation and passivation, and the materials do not react in a packaging bag to achieve the purpose of safety and stability of the disinfectant, so that the storage time of the product is remarkably prolonged.
Detailed Description
The invention is further described below by way of examples:
example 1
The composite coating agent is prepared by fully and uniformly mixing 35 parts by weight of polyvinyl alcohol, 15 parts by weight of polyvinylpyrrolidone, 8 parts by weight of cobalt chloride and 42 parts by weight of water for later use.
25 parts by weight of sodium chlorite and 2 parts by weight of sodium percarbonate are put into a mixer, 18 parts by weight of a composite coating agent is continuously sprayed in the mixer in a stirring state for stirring and mixing, and the coated particles are dried to obtain 37 parts by weight of a coating matrix.
The trichloroisocyanuric acid is crushed into powder of 200-400 meshes, 11 parts by weight of the trichloroisocyanuric acid powder is uniformly mixed with 42 parts by weight of citric acid, and 53 parts by weight of the composite activator is prepared.
The magnesium sulfate is crushed, sieved and dried to ensure that the granularity of the powder is not less than 50 meshes and the water content is not more than 3 percent. Taking 10 parts by weight of magnesium sulfate powder, uniformly mixing the magnesium sulfate powder with 37 parts by weight of coating matrix, pouring 53 parts by weight of composite exciting agent into the mixture, uniformly mixing, and carrying out polyethylene film inner packaging and aluminum-plastic outer packaging treatment to obtain the mono-packaged solid stable chlorine dioxide disinfectant with 15% of chlorine dioxide content.
Example 2
Uniformly mixing 30 parts by weight of polyvinyl alcohol, 12 parts by weight of polyvinylpyrrolidone, 10 parts by weight of cobalt chloride and 48 parts by weight of water to obtain the composite coating agent for later use.
27 parts by weight of sodium chlorite and 3 parts by weight of sodium percarbonate were put into a mixer, 25 parts by weight of a composite coating agent was continuously sprayed and stirred to mix, and the coated particles were dried to obtain 43 parts by weight of a coated matrix.
The trichloroisocyanuric acid is crushed into powder of 200-400 meshes, 5 parts by weight of the trichloroisocyanuric acid powder is uniformly mixed with 12 parts by weight of citric acid and 29 parts by weight of sulfamic acid, and 46 parts by weight of the composite activator is prepared.
Respectively pulverizing magnesium sulfate and calcium chloride, sieving, and drying to obtain powder with particle size of not less than 50 meshes and water content of not more than 3%. And (2) taking 7 parts by weight of magnesium sulfate powder and 4 parts by weight of calcium chloride powder, uniformly mixing the magnesium sulfate powder and 43 parts by weight of coating matrix, pouring 46 parts by weight of composite exciting agent into the mixture, uniformly mixing, and carrying out polyethylene film inner packaging and aluminum-plastic outer packaging treatment to obtain the mono-packaged solid stable chlorine dioxide disinfectant with 14% of chlorine dioxide content.
Claims (4)
1. A solid stable chlorine dioxide disinfectant consists of sodium chlorite, solid acid and a coating agent, and is characterized in that the coating agent consists of polyvinyl alcohol, polyvinylpyrrolidone, cobalt chloride and water, and the components in parts by weight are as follows: 30-50 parts of polyvinyl alcohol, 10-20 parts of polyvinylpyrrolidone, 5-10 parts of cobalt chloride and 30-55 parts of water, 19-27 parts of sodium chlorite and 1-3 parts of sodium percarbonate are mixed, and then a coating agent is coated on the surfaces of the sodium chlorite and the sodium percarbonate to prepare the disinfectant consisting of a coating matrix.
2. The solid stable chlorine dioxide disinfectant as set forth in claim 1, wherein a passivating agent is added to the disinfectant, said passivating agent is composed of magnesium sulfate and calcium chloride, and each component is calculated by weight: 5-10 parts of magnesium sulfate and 5-10 parts of calcium chloride.
3. The solid stable chlorine dioxide disinfectant as setforth in claim 1 or 2, wherein a compound activator is added into the disinfectant, the compound activator is composed of trichloroisocyanuric acid and citric acid or sulfamic acid, and the components are calculated by weight: 5-15 parts of trichloroisocyanuric acid and 30-50 parts of citric acid or sulfamic acid.
4. A preparation method of a solid stable chlorine dioxide disinfectant is characterized by comprising the following steps:
a. uniformly mixing polyvinyl alcohol, polyvinylpyrrolidone, cobalt chloride and water according to a ratio to prepare the composite coating agent, wherein the composite coating agent comprises the following components in parts by weight: 30-50% of polyvinyl alcohol, 10-20% of polyvinylpyrrolidone, 5-10% of cobalt chloride and 30-55% of water;
b. putting sodium chlorite and sodium percarbonate into a mixer, continuously spraying a composite coating agent, stirring and mixing, and drying the coated particles to obtain a coating matrix;
c. crushing trichloroisocyanuric acid into powder of 200-400 meshes, and uniformly mixing with citric acid or sulfamic acid to prepare a composite excitant;
d. respectively pulverizing magnesium sulfate and calcium chloride, sieving, drying, mixing with the coated matrix, adding compound activator, mixing, and packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03121406 CN1209970C (en) | 2003-03-28 | 2003-03-28 | Solid stable chlorinedioxide antiseptics and preparation thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03121406 CN1209970C (en) | 2003-03-28 | 2003-03-28 | Solid stable chlorinedioxide antiseptics and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1439268A true CN1439268A (en) | 2003-09-03 |
| CN1209970C CN1209970C (en) | 2005-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 03121406 Expired - Fee Related CN1209970C (en) | 2003-03-28 | 2003-03-28 | Solid stable chlorinedioxide antiseptics and preparation thereof |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391343C (en) * | 2006-12-06 | 2008-06-04 | 刘桂发 | Monophyletic solid disinfectant of chlorine dioxide and preparation method thereof |
| CN101803610A (en) * | 2010-03-22 | 2010-08-18 | 北京欧凯纳斯科技有限公司 | Self regulation and control type chlorine dioxide combination and application thereof in tobacco warehouse storage |
| CN102160552A (en) * | 2011-02-22 | 2011-08-24 | 天津市华阳新兴科技有限公司 | Controlled-release coated chlorine dioxide disinfectant |
| CN102239884A (en) * | 2011-04-29 | 2011-11-16 | 广东省微生物研究所 | Mildewproof agent for leather shoes and preparation method thereof |
| CN101491257B (en) * | 2009-03-05 | 2012-05-09 | 河北科技大学 | Effervescence type disinfection deodorizer and preparation method thereof |
| CN102791621A (en) * | 2010-02-02 | 2012-11-21 | 巴斯夫欧洲公司 | Encapsulated chlorine dioxide generator |
| US8992831B2 (en) | 2009-09-25 | 2015-03-31 | E. I. Du Pont De Nemours And Company | Stabilized chlorine dioxide to preserve carbohydrate feedstocks |
| CN104686574A (en) * | 2013-12-05 | 2015-06-10 | 无锡钻石地毯制造有限公司 | Ecological carpet eco-friendly mildew inhibitor |
| CN104686570A (en) * | 2013-12-05 | 2015-06-10 | 无锡市锡源锅炉有限公司 | Environmentally-friendly mildew inhibitor for drying furnace |
| CN107593762A (en) * | 2017-09-29 | 2018-01-19 | 广州闪电生物科技有限公司 | A kind of antiseptic solution and sterilization method |
| CN108751385A (en) * | 2018-04-24 | 2018-11-06 | 苏州国科芯感医疗科技有限公司 | Solid chlorine dioxide slow-release material and preparation method thereof |
| CN112408563A (en) * | 2021-01-25 | 2021-02-26 | 湖南海鸥环保科技有限公司 | Water body remediation agent and preparation and application methods thereof |
| CN114027319A (en) * | 2021-12-15 | 2022-02-11 | 佛山市南海东方澳龙制药有限公司 | Chlorine dioxide disinfectant and preparation method thereof |
-
2003
- 2003-03-28 CN CN 03121406 patent/CN1209970C/en not_active Expired - Fee Related
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391343C (en) * | 2006-12-06 | 2008-06-04 | 刘桂发 | Monophyletic solid disinfectant of chlorine dioxide and preparation method thereof |
| CN101491257B (en) * | 2009-03-05 | 2012-05-09 | 河北科技大学 | Effervescence type disinfection deodorizer and preparation method thereof |
| US8992831B2 (en) | 2009-09-25 | 2015-03-31 | E. I. Du Pont De Nemours And Company | Stabilized chlorine dioxide to preserve carbohydrate feedstocks |
| US9504710B2 (en) | 2009-09-25 | 2016-11-29 | E I Du Pont De Nemours And Company | Stabilized chlorine dioxide to preserve carbohydrate feedstocks |
| CN102791621A (en) * | 2010-02-02 | 2012-11-21 | 巴斯夫欧洲公司 | Encapsulated chlorine dioxide generator |
| CN102791621B (en) * | 2010-02-02 | 2014-12-24 | 巴斯夫欧洲公司 | Encapsulated chlorine dioxide generator |
| CN101803610A (en) * | 2010-03-22 | 2010-08-18 | 北京欧凯纳斯科技有限公司 | Self regulation and control type chlorine dioxide combination and application thereof in tobacco warehouse storage |
| CN101803610B (en) * | 2010-03-22 | 2012-07-18 | 北京欧凯纳斯科技有限公司 | Self regulation and control type chlorine dioxide combination and application thereof in tobacco warehouse storage |
| CN102160552A (en) * | 2011-02-22 | 2011-08-24 | 天津市华阳新兴科技有限公司 | Controlled-release coated chlorine dioxide disinfectant |
| CN102160552B (en) * | 2011-02-22 | 2013-06-12 | 天津市华阳新兴科技有限公司 | Controlled-release coated chlorine dioxide disinfectant |
| CN102239884B (en) * | 2011-04-29 | 2013-07-31 | 广东省微生物研究所 | Mildewproof agent for leather shoes and preparation method thereof |
| CN102239884A (en) * | 2011-04-29 | 2011-11-16 | 广东省微生物研究所 | Mildewproof agent for leather shoes and preparation method thereof |
| CN104686574A (en) * | 2013-12-05 | 2015-06-10 | 无锡钻石地毯制造有限公司 | Ecological carpet eco-friendly mildew inhibitor |
| CN104686570A (en) * | 2013-12-05 | 2015-06-10 | 无锡市锡源锅炉有限公司 | Environmentally-friendly mildew inhibitor for drying furnace |
| CN107593762A (en) * | 2017-09-29 | 2018-01-19 | 广州闪电生物科技有限公司 | A kind of antiseptic solution and sterilization method |
| CN107593762B (en) * | 2017-09-29 | 2020-10-27 | 广州闪电生物科技有限公司 | Disinfecting solution and disinfecting method |
| CN108751385A (en) * | 2018-04-24 | 2018-11-06 | 苏州国科芯感医疗科技有限公司 | Solid chlorine dioxide slow-release material and preparation method thereof |
| CN112408563A (en) * | 2021-01-25 | 2021-02-26 | 湖南海鸥环保科技有限公司 | Water body remediation agent and preparation and application methods thereof |
| CN114027319A (en) * | 2021-12-15 | 2022-02-11 | 佛山市南海东方澳龙制药有限公司 | Chlorine dioxide disinfectant and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1209970C (en) | 2005-07-13 |
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Granted publication date: 20050713 Termination date: 20110328 |