CN107593762B - Disinfecting solution and disinfecting method - Google Patents
Disinfecting solution and disinfecting method Download PDFInfo
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- CN107593762B CN107593762B CN201710927141.1A CN201710927141A CN107593762B CN 107593762 B CN107593762 B CN 107593762B CN 201710927141 A CN201710927141 A CN 201710927141A CN 107593762 B CN107593762 B CN 107593762B
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- 230000000249 desinfective Effects 0.000 title claims abstract description 87
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 78
- OSVXSBDYLRYLIG-UHFFFAOYSA-N Chlorine dioxide Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 claims abstract description 70
- 238000010438 heat treatment Methods 0.000 claims abstract description 48
- 239000004155 Chlorine dioxide Substances 0.000 claims abstract description 35
- 235000019398 chlorine dioxide Nutrition 0.000 claims abstract description 35
- 238000003958 fumigation Methods 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 239000003381 stabilizer Substances 0.000 claims abstract description 5
- 230000001954 sterilising Effects 0.000 claims description 24
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- UXVMQQNJUSDDNG-UHFFFAOYSA-L cacl2 Chemical group [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 11
- SUKJFIGYRHOWBL-UHFFFAOYSA-N Sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 9
- 239000005708 Sodium hypochlorite Substances 0.000 claims description 9
- 238000004806 packaging method and process Methods 0.000 claims description 9
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 239000002274 desiccant Substances 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 239000005711 Benzoic acid Substances 0.000 claims description 4
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 claims description 4
- YZHUMGUJCQRKBT-UHFFFAOYSA-M Sodium chlorate Chemical compound [Na+].[O-]Cl(=O)=O YZHUMGUJCQRKBT-UHFFFAOYSA-M 0.000 claims description 4
- UKLNMMHNWFDKNT-UHFFFAOYSA-M Sodium chlorite Chemical compound [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 claims description 4
- VHUUQVKOLVNVRT-UHFFFAOYSA-N ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims description 4
- 235000011114 ammonium hydroxide Nutrition 0.000 claims description 4
- 235000010233 benzoic acid Nutrition 0.000 claims description 4
- 239000002131 composite material Substances 0.000 claims description 4
- 229940080281 sodium chlorate Drugs 0.000 claims description 4
- 229960002218 sodium chlorite Drugs 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- 229960001367 tartaric acid Drugs 0.000 claims description 4
- 239000011975 tartaric acid Substances 0.000 claims description 4
- 235000002906 tartaric acid Nutrition 0.000 claims description 4
- 235000015165 citric acid Nutrition 0.000 claims description 2
- 229960005076 sodium hypochlorite Drugs 0.000 claims description 2
- 239000000460 chlorine Substances 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000006258 conductive agent Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 13
- XTEGARKTQYYJKE-UHFFFAOYSA-M chlorate Chemical compound [O-]Cl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-M 0.000 abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 238000005457 optimization Methods 0.000 description 9
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 6
- 229910052708 sodium Inorganic materials 0.000 description 6
- 239000011734 sodium Substances 0.000 description 6
- MSFGZHUJTJBYFA-UHFFFAOYSA-M Sodium dichloroisocyanurate Chemical compound [Na+].ClN1C(=O)[N-]C(=O)N(Cl)C1=O MSFGZHUJTJBYFA-UHFFFAOYSA-M 0.000 description 5
- YRIZYWQGELRKNT-UHFFFAOYSA-N Trichloroisocyanuric acid Chemical compound ClN1C(=O)N(Cl)C(=O)N(Cl)C1=O YRIZYWQGELRKNT-UHFFFAOYSA-N 0.000 description 5
- 239000001488 sodium phosphate Substances 0.000 description 5
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 5
- 229910000406 trisodium phosphate Inorganic materials 0.000 description 5
- 235000019801 trisodium phosphate Nutrition 0.000 description 5
- 239000001110 calcium chloride Substances 0.000 description 4
- 229910001628 calcium chloride Inorganic materials 0.000 description 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N edta Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 4
- -1 perfluorononenoxybenzene sulfonate Chemical compound 0.000 description 4
- 229920001661 Chitosan Polymers 0.000 description 3
- 229940051841 POLYOXYETHYLENE ETHER Drugs 0.000 description 3
- 229940005550 Sodium alginate Drugs 0.000 description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 3
- 230000004059 degradation Effects 0.000 description 3
- 238000006731 degradation reaction Methods 0.000 description 3
- 239000008367 deionised water Substances 0.000 description 3
- 229920000056 polyoxyethylene ether Polymers 0.000 description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 3
- MSXHSNHNTORCAW-UHFFFAOYSA-M sodium 3,4,5,6-tetrahydroxyoxane-2-carboxylate Chemical compound [Na+].OC1OC(C([O-])=O)C(O)C(O)C1O MSXHSNHNTORCAW-UHFFFAOYSA-M 0.000 description 3
- 239000000661 sodium alginate Substances 0.000 description 3
- 235000010413 sodium alginate Nutrition 0.000 description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 3
- DUIOKRXOKLLURE-UHFFFAOYSA-N 2-octylphenol Chemical compound CCCCCCCCC1=CC=CC=C1O DUIOKRXOKLLURE-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 238000000889 atomisation Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 230000002708 enhancing Effects 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 description 1
- QWYXNPUTSOVWEA-UHFFFAOYSA-N 2-octylphenol;sodium Chemical compound [Na].CCCCCCCCC1=CC=CC=C1O QWYXNPUTSOVWEA-UHFFFAOYSA-N 0.000 description 1
- 241001270131 Agaricus moelleri Species 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N Fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 229940067606 Lecithin Drugs 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L Sodium thiosulphate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 229940076185 Staphylococcus aureus Drugs 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L Sulphite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000003044 adaptive Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- XPXMKIXDFWLRAA-UHFFFAOYSA-N hydrazinide Chemical compound [NH-]N XPXMKIXDFWLRAA-UHFFFAOYSA-N 0.000 description 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000006011 modification reaction Methods 0.000 description 1
- 230000003000 nontoxic Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 238000003359 percent control normalization Methods 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Abstract
The invention discloses a disinfection solution, which is prepared from the following raw materials in parts by weight: 50-70 parts of chlorate, 0.1-1 part of stabilizer, 0-1 part of passivator and 10-30 parts of trigger; the invention also discloses a disinfection method, which comprises the following steps: pouring the disinfection solution into an inner container of the gas fumigation disinfection device, adjusting the heating temperature and the heating time of the gas fumigation disinfection device, and diffusing chlorine dioxide gas into the environment from the inner container; the disinfection solution and the disinfection method of the invention are adopted to disinfect the environment, the consumption of the needed disinfection gas is less, the disinfection effect is good, the humidity of the space is not changed, and the environment is not corroded.
Description
Technical Field
The invention relates to the technical field of disinfection, in particular to a disinfection solution and a disinfection method.
Background
In order to adapt to the fumigation of the chlorine dioxide disinfectant, the prior art diffuses the disinfectant and water molecules into the space through ultrasonic atomization or high-pressure atomization, so as to achieve the disinfection effect. However, chlorine dioxide molecules brought out by water molecules change the humidity of the space, the diffusion effect is limited, and the combination of chlorine dioxide and water molecules aggravates the corrosiveness to the environment.
Disclosure of Invention
Based on the above, the invention aims to overcome the defects of the prior art and provide a disinfection method which has good disinfection effect, does not change the space humidity and is more environment-friendly.
In order to realize the purpose, the invention adopts the following technical scheme:
as one aspect of the present invention, the present invention provides a disinfectant solution, which is prepared from the following raw materials in parts by weight: 50-70 parts of chlorate, 0.1-1 part of stabilizer, 0-1 part of passivator and 10-30 parts of trigger. Thus, the disinfection solution has longer shelf life and lower chlorine dioxide degradation rate.
As a further optimization of the scheme, the raw materials for preparing the disinfection solution also comprise 1-2 parts of surfactant. Preferably, the surfactant is at least one of gemini fluorocarbon, sodium perfluorononenoxybenzene sulfonate, sodium dodecyl sulfate and octyl phenol polyoxyethylene ether (OP-10); therefore, the surfactant can improve the lipophilicity of the disinfection solution, improve the physical surface adhesive force of the disinfection solution, and enable the disinfection solution to be fully contacted with the physical surface, thereby enhancing the disinfection effect of the disinfection solution.
As a further optimization of the scheme, the raw materials for preparing the disinfection solution also comprise 1-10 parts of a heat-conducting agent. Preferably, the heat conducting agent is ethanol or ammonia water. Therefore, the heat conducting agent can conduct heat to the disinfection solution more quickly, the disinfection solution is more sensitive to heat, the disinfectant can form disinfection gas more quickly, the disinfection gas escapes from the solution, and moisture cannot be brought out.
Preferably, the chlorate is at least one of sodium chlorate, sodium chlorite and sodium hypochlorite.
Preferably, the passivating agent is at least one of chitosan, sodium alginate and sodium carboxymethyl cellulose; therefore, the passivating agent can relieve the speed of the chlorine dioxide gas released by the disinfecting solution, so that the disinfecting effect of the chlorine dioxide is continuous, and the chlorine dioxide disinfecting solution is safe and non-toxic to the environment.
As a further optimization of the above scheme, the stabilizer is at least one of EDTA, polyvinylpyrrolidone, pentamethylene aminocarboxylic acid, amino alcohol and amide. Therefore, the stabilizer can inhibit the decomposition of the chlorine dioxide in the disinfection solution and prolong the storage life of the chlorine dioxide disinfection solution.
As a further optimization of the above scheme, the trigger is at least one of citric acid, benzoic acid and tartaric acid. Thus, the trigger (activator) can react with chlorate to generate chlorine dioxide gas, thereby achieving the disinfection effect.
As a further optimization of the above scheme, the raw materials for preparing the disinfection solution further comprise at least one of sodium trichloroisocyanurate, sodium dichloroisocyanurate and trisodium phosphate; therefore, the content of the sodium trichloroisocyanurate, the sodium dichloroisocyanurate or the trisodium phosphate is 0-10 parts by weight, and the sodium trichloroisocyanurate, the sodium dichloroisocyanurate or the trisodium phosphate can be synergistically acted with the chlorine dioxide to enhance the disinfection effect of the chlorine dioxide.
As a second aspect of the present invention, there is also provided a sterilization method comprising the steps of: pouring the disinfection solution (the disinfection solution preparation raw material comprises a heat conducting agent) into an inner container of a gas fumigation device, adjusting the heating temperature and the heating time of the gas fumigation device, and diffusing chlorine dioxide gas into the environment from the inner container;
wherein, gaseous fumigation degassing unit includes the casing, be equipped with the heating jacket in the casing, be equipped with the detachable inner bag in the heating jacket, be equipped with temperature controller, heating time controller and integrated controller on the casing, temperature controller respectively with integrated controller with the heating jacket is connected, heating time controller respectively with integrated controller with the heating jacket is connected. It should be noted that the inner container is filled with a solution of gas to be heated for sterilization, and the temperature controller is used for controlling the temperature of the heating sleeve; the heating time of the heating jacket to the sterilizing solution is controlled by the heating time controller, so that a better sterilizing effect is realized.
Therefore, the disinfectant solution to be fumigated is directly poured into the inner container, and then the inner container is put into the heating sleeve; the temperature controller is adjusted by changing the power setting, and the high-middle-low three-gear fumigating speed is set, so that the temperature of the liquid in the liner is controlled, the higher the temperature is, the faster the chlorine dioxide disinfectant escapes to the environment, and the heat conducting agent can conduct heat to the disinfecting solution more quickly, so that the escape speed of the chlorine dioxide is higher, and the moisture brought out is less; the inner container can be taken out and cleaned as required; and a heating time controller is used for setting three stages of continuous fumigation, intermittent fumigation and fumigation time to perform adaptive disinfection on the environment.
As a further optimization of the scheme, the top of the inner container is provided with a top cover with holes, a gap is formed in the middle of the top cover, and a drying agent is filled in the gap. Thus, the desiccant can absorb the water vapor volatilized by heating, avoiding changing the humidity of the sterilized environment.
As a further optimization of the scheme, the drying agent is anhydrous calcium chloride, the anhydrous calcium chloride is sealed by a packaging bag, and the packaging bag is made of a DuPont paper composite breathable film. Therefore, the calcium chloride does not react with the chlorine dioxide, the water vapor evaporated along with the chlorine dioxide is absorbed by the calcium chloride, and the chlorine dioxide can smoothly pass through the top cover to achieve the sterilized environment; the packaging bag seals the anhydrous calcium chloride to prevent the calcium chloride powder from entering the disinfection solution in the inner container; in addition, the packaging bag made of the DuPont paper composite breathable film can prevent liquid drops formed after calcium chloride absorbs water from permeating into the inner container, and meanwhile, the breathable film can pass through disinfection gas such as chlorine dioxide volatilized from the inner container.
As a further optimization of the scheme, the heating temperature is 10-30 ℃, and preferably 22 ℃. Thus, the lower heating temperature results in less water vapor being carried over by the sterilizing gas and a lower increase in ambient humidity.
As a further optimization of the above scheme, the top cover is arc-shaped. Therefore, the sterilizing gas can be volatilized into the environment through the small holes on the arc-shaped top cover, the area of the arc-shaped top cover is larger than that of the flat top cover, and the sterilizing gas can be diffused into the environment at a higher speed; radial small holes can be densely distributed on the arc-shaped top cover to enlarge the diffusion efficiency of the sterilizing gas.
In conclusion, the beneficial effects of the invention are as follows:
the disinfection solution and the disinfection method of the invention are adopted to disinfect the environment, the consumption of the needed disinfection gas is less, the disinfection effect is good, the humidity of the space is not changed, and the environment is not corroded.
Drawings
FIG. 1 is a sectional view of example 1 of the present invention;
FIG. 2 is an enlarged view of a portion of the structure of FIG. 1;
the drying device comprises a shell 1, a shell 2, a heating sleeve 3, an inner container 4, a temperature controller 5, an integrated controller 6, a time controller 7, a top cover 8, a gap 9, a drying agent 10 and a packaging bag.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to the accompanying drawings and specific embodiments.
Example 1
As shown in fig. 1 and 2, an embodiment of the gas fumigation device of the present invention includes a housing 1, a heating jacket 2 is disposed in the housing 1, a detachable liner 3 is disposed in the heating jacket 2, the top of the liner 3 extends out of the housing 1, a temperature controller 4, a heating time controller 6 and an integrated controller 5 are disposed on the housing 1, the temperature controller 4 is respectively connected with the integrated controller 5 and the heating jacket 2, and the heating time controller 6 is respectively connected with the integrated controller 5 and the heating jacket 2;
a top cover 7 with densely distributed small holes is arranged at the top of the inner container, a gap 8 is arranged in the middle of the top cover, and a drying agent 9 is filled in the gap 8; the desiccant 9 is anhydrous calcium chloride; the top cover 7 is arc-shaped; the anhydrous calcium chloride is sealed by a packaging bag 10, and the packaging bag 10 is made of DuPont paper composite breathable films.
The heating temperature of the heating jacket can be 40-50 ℃ according to the requirement, and the chlorine dioxide gas can be volatilized into the environment at low speed and low concentration; or the temperature is 50-60 ℃, the chlorine dioxide gas can be volatilized into the environment at a medium speed and a medium concentration, and the disinfection efficiency and the low corrosivity are achieved; or the temperature is 60-80 ℃, and the chlorine dioxide gas can be volatilized into the environment at high speed and high concentration.
Example 2
According to one embodiment of the disinfectant solution, the preparation raw materials comprise the following components in parts by mass: 50 parts of sodium hypochlorite, 0.1 part of EDTA, 20 parts of citric acid, 1 part of sodium dodecyl sulfate, 0.01 part of sodium alginate, 10 parts of ammonia water and 0.1 part of sodium trichloroisocyanurate.
The preparation method of the disinfection solution comprises the following steps: 50 parts of sodium hypochlorite, 0.1 part of EDTA (ethylene diamine tetraacetic acid), 20 parts of citric acid, 1 part of sodium dodecyl sulfate, 0.01 part of sodium alginate, 10 parts of ammonia water and 0.1 part of sodium trichloroisocyanurate are dissolved by 60 parts of deionized water, and when the concentration variation of chlorine dioxide in the solution is less than 10% of the initial concentration, the solution reaches balance, namely the disinfection solution.
Example 3
According to one embodiment of the disinfectant solution, the preparation raw materials comprise the following components in parts by mass: 30 parts of sodium chlorate, 30 parts of sodium hypochlorite, 0.5 part of polyvinylpyrrolidone, 10 parts of benzoic acid, 1.4 parts of perfluorononenoxybenzene sodium sulfonate, 0.55 part of chitosan, 6 parts of ethanol and 5.8 parts of sodium dichloroisocyanurate.
The preparation method of the disinfection solution comprises the following steps: 30 parts of sodium chlorate, 30 parts of sodium hypochlorite, 0.5 part of polyvinylpyrrolidone, 10 parts of benzoic acid, 1.4 parts of perfluorononenoxy sodium benzenesulfonate, 0.55 part of chitosan, 6 parts of ethanol and 5.8 parts of sodium dichloroisocyanurate, and the components are dissolved by 44 parts of deionized water, and when the concentration variation of chlorine dioxide in the solution is less than 10% of the initial concentration, the solution reaches equilibrium, namely the disinfection solution.
Example 4
According to one embodiment of the disinfectant solution, the preparation raw materials comprise the following components in parts by mass: 30 parts of sodium chlorite, 40 parts of sodium hypochlorite, 1 part of L-aminopropanol, 30 parts of tartaric acid, 2 parts of octyl phenol polyoxyethylene ether, 1 part of sodium carboxymethylcellulose, 1 part of ethanol and 10 parts of trisodium phosphate.
The preparation method of the disinfection solution comprises the following steps: 30 parts of sodium chlorite, 40 parts of sodium hypochlorite, 1 part of L-aminopropanol, 30 parts of tartaric acid, 2 parts of octyl phenol polyoxyethylene ether, 1 part of sodium carboxymethylcellulose, 1 part of ethanol and 10 parts of trisodium phosphate, and dissolving the components by using 30 parts of deionized water, and when the concentration variation of chlorine dioxide in the solution is less than 10% of the initial concentration, balancing the solution to obtain the disinfection solution.
Example 5
One embodiment of the sterilization method of the present invention comprises the steps of: the disinfectant solution of example 2 was poured into the inner container of the gas fumigation apparatus of example 1, the heating temperature was set to 57 ℃, the heating time was set to be continuous heating, and chlorine dioxide gas was diffused from the inner container into the ambulance to disinfect.
Example 6
One embodiment of the sterilization method of the present invention comprises the steps of: the disinfectant solution of example 3 was poured into the inner container of the gas fumigation apparatus of example 1, and chlorine dioxide gas was diffused from the inner container into the ambulance to disinfect it at a heating temperature of 44 c for 3 hours.
Example 7
One embodiment of the sterilization method of the present invention comprises the steps of: the disinfectant solution of example 4 was poured into the inner container of the gas fumigation apparatus of example 1, the heating temperature was set to 73 ℃, the heating time was set to 15 minutes, and the heating was stopped for 15 minutes in a cyclic mode, and chlorine dioxide gas was diffused from the inner container into the ambulance to disinfect it.
Example 8 testing of the degradation Rate of the Disinfection solution of the present invention
Test objects: the main component of the disinfection solution of the embodiment 2-4 and the existing 84 disinfection solution used as a control group is sodium hypochlorite, and the content of chlorine dioxide is 6% by mass;
the test method comprises the following steps: 2.2.3 determination of the stability of the sterilized products, the samples are stored in an incubator at 37 ℃ for 90 days, according to the technical Specification for Sterilization, 2002; detecting according to a method for measuring the content of chlorine dioxide of 2002 edition 2.2.1.2.3 of disinfection technical Specification; and (3) testing results: as shown in table 1 below.
TABLE 1 degradation rate of the disinfectant solutions of the present invention
| Test object | Rate of decrease in chlorine dioxide content |
| Disinfectant solution of example 2 | 5.7％ |
| Disinfectant solution of example 3 | 3.1％ |
| Disinfectant solution of example 4 | 6.2％ |
| Control group | 11.4％ |
And (4) analyzing results: as shown in table 1 above, the disinfection solutions of examples 2 to 4 have a chlorine dioxide content reduction rate of 5.7%, 3.1%, 6.2%, respectively, and meet the requirement of the disinfection specification that the content reduction rate of active ingredients is less than or equal to 10%; the content reduction rate of 84 disinfectant chlorine dioxide used as a control group is slightly higher than 10%.
Example 9 test of the sterilizing effect of the sterilizing method of the present invention
Test objects: the disinfection methods of examples 5 to 7 and the disinfection method of low-temperature fumigation at 10 to 30 ℃ as a control group (compared with example 6, the difference is only the heating temperature);
the test method comprises the following steps: testing the killing logarithm value of staphylococcus aureus and natural bacteria on the surface of an object by taking a PBS solution containing 1% of lecithin, 1% of Tween 80, 1% of sodium thiosulfate and 1% of glycine as a neutralizer at the temperature of 21-22 ℃, and testing the killing logarithm value of the natural bacteria on the surface of the object, wherein the sterilization technical specification (2002 edition);
and (3) testing results: as shown in table 2 below;
TABLE 2 Disinfection Effect of the Disinfection method of the present invention
And (4) analyzing results: as can be seen from table 2 above, the sterilization method of the present invention has a good sterilization effect, and particularly, the sterilization effect is better when the heating temperature is 10 to 30 ℃ in the low-temperature fumigation sterilization method, wherein the sterilization effect is the best when the heating temperature is 22 ℃.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (4)
1. A sterilization method, comprising the steps of: pouring the disinfection solution into an inner container of the gas fumigation disinfection device, adjusting the heating temperature and the heating time of the gas fumigation disinfection device, and diffusing chlorine dioxide gas into the environment from the inner container;
the gas fumigation device comprises a shell, a heating sleeve is arranged in the shell, a detachable inner container is arranged in the heating sleeve, a temperature controller, a heating time controller and an integrated controller are arranged on the shell, the temperature controller is respectively connected with the integrated controller and the heating sleeve, and the heating time controller is respectively connected with the integrated controller and the heating sleeve;
the top of the inner container is provided with a top cover with holes, a gap is arranged in the middle of the top cover, and a drying agent is filled in the gap;
the drying agent is anhydrous calcium chloride, the anhydrous calcium chloride is sealed by a packaging bag, and the packaging bag is made of a DuPont paper composite breathable film;
the heating temperature is 10-30 ℃;
the preparation raw materials of the disinfection solution comprise the following components in parts by weight: 50-70 parts of chlorine-containing compound, 0.1-1 part of stabilizer, 0-1 part of passivator, 1-2 parts of surfactant, 1-10 parts of heat conducting agent and 10-30 parts of trigger; the chlorine-containing compound is at least one of sodium chlorate, sodium chlorite and sodium hypochlorite.
2. The sterilization method according to claim 1, wherein the heat conductive agent is ethanol or ammonia water.
3. The sterilization method according to claim 1, wherein the trigger is at least one of citric acid, benzoic acid, and tartaric acid.
4. A sterilization process according to claim 1, wherein the heating temperature is 22 ℃.
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Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1238130A (en) * | 1999-06-14 | 1999-12-15 | 宋红安 | Powdered CLO2 disinfectant and preparing process thereof |
| CN1439268A (en) * | 2003-03-28 | 2003-09-03 | 河北科技大学 | Solid stable chlorinedioxide antiseptics and preparation thereof |
| CN1631769A (en) * | 2003-12-23 | 2005-06-29 | 青岛大学 | Method for preparing solid stabilized chlorine dioxide disinfectant |
| CN1969633A (en) * | 2006-12-06 | 2007-05-30 | 刘桂发 | Monophyletic solid disinfectant of chlorine dioxide and preparation method thereof |
| CN101124914A (en) * | 2007-10-03 | 2008-02-20 | 胡银安 | Mixing disinfectant containing chlorine dioxide and preparing process thereof |
| CN101491257A (en) * | 2009-03-05 | 2009-07-29 | 河北科技大学 | Effervescence type disinfection deodorizer and preparation method thereof |
| CN101695305A (en) * | 2009-10-30 | 2010-04-21 | 张家口市净宇天成化工有限公司 | Solid preparation of chlorine dioxide |
| CN101898078A (en) * | 2010-07-19 | 2010-12-01 | 陈学成 | Slow-release indoor disinfecting and decoration odor removing agent and production method and use method thereof |
| CN102283247A (en) * | 2011-07-23 | 2011-12-21 | 中国农业科学院兰州畜牧与兽药研究所 | Veterinary disinfection powder and preparation method thereof |
| CN104012571A (en) * | 2013-08-29 | 2014-09-03 | 四川省龙天源环保设备制造有限公司 | Chlorine dioxide air disinfectant and preparation method thereof |
| CN204379737U (en) * | 2015-01-09 | 2015-06-10 | 刘婧 | Infectious Disease's sterilizing therapeutic apparatus |
| CN204542971U (en) * | 2015-03-02 | 2015-08-12 | 吉林省利泽生物科技有限公司 | A kind of chlorine dioxide device for fumigation |
| CN204655472U (en) * | 2015-02-12 | 2015-09-23 | 成都迅德科技有限公司 | Device for fumigation |
| CN105381492A (en) * | 2015-12-09 | 2016-03-09 | 深圳万和制药有限公司 | Method and device for releasing chlorine dioxide to space environment |
| CN105963747A (en) * | 2016-04-28 | 2016-09-28 | 兰州泰坦生物科技有限责任公司 | Chlorine dioxide sustained-release device and chlorine dioxide replenisher thereof |
| CN106818862A (en) * | 2017-01-22 | 2017-06-13 | 清远海贝生物技术有限公司 | A kind of high efficiency chlorine dioxide solution without activation and its production and use |
| CN107018990A (en) * | 2017-04-05 | 2017-08-08 | 南昌大学 | A kind of disinfectant of decomposable asymmetric choice net formaldehyde |
| CN206434708U (en) * | 2016-11-09 | 2017-08-25 | 南宁太空节能科技有限公司 | Anion human body purification barrel |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1264539A (en) * | 1999-02-26 | 2000-08-30 | 崔永成 | Weakly acidic disinfectant |
| CA2399245A1 (en) * | 2000-02-18 | 2001-08-23 | Selective Micro Technologies, Llc | Apparatus and method for controlled delivery of a gas |
| US7150854B2 (en) * | 2002-03-19 | 2006-12-19 | Engelhard Corporation | Device for generating aqueous chlorine dioxide solutions |
| US20060006361A1 (en) * | 2004-07-08 | 2006-01-12 | Joseph Callerame | Clathrate of chlorine dioxide |
| US20060039841A1 (en) * | 2004-08-18 | 2006-02-23 | Avantec Technologies, Inc. | Systems and methods for producing aqueous solutions and gases having disinfecting properties and substantially eliminating impurities |
| EA014821B1 (en) * | 2005-08-04 | 2011-02-28 | Сэйбэн Венчерз Пти Лимитед | Apparatus for concentrating a nebulant |
| US20120164056A1 (en) * | 2009-07-01 | 2012-06-28 | Haddad Louis C | Generation of sterilant gasses and uses thereof |
| JP2012036072A (en) * | 2010-08-09 | 2012-02-23 | Cleancare Inc | Product shape and component composition of chlorine dioxide generator at using time |
| US20130136685A1 (en) * | 2011-11-25 | 2013-05-30 | Juan Carlos Baselli | Portable Chlorie Dioxide Generator |
| CN206238172U (en) * | 2016-10-13 | 2017-06-13 | 贵州嘉利达科技有限公司 | Hydrogen phosphide and carbon dioxide gas mixture device for fumigation outside storehouse |
-
2017
- 2017-09-29 CN CN201710927141.1A patent/CN107593762B/en active Active
Patent Citations (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1238130A (en) * | 1999-06-14 | 1999-12-15 | 宋红安 | Powdered CLO2 disinfectant and preparing process thereof |
| CN1439268A (en) * | 2003-03-28 | 2003-09-03 | 河北科技大学 | Solid stable chlorinedioxide antiseptics and preparation thereof |
| CN1631769A (en) * | 2003-12-23 | 2005-06-29 | 青岛大学 | Method for preparing solid stabilized chlorine dioxide disinfectant |
| CN1969633A (en) * | 2006-12-06 | 2007-05-30 | 刘桂发 | Monophyletic solid disinfectant of chlorine dioxide and preparation method thereof |
| CN101124914A (en) * | 2007-10-03 | 2008-02-20 | 胡银安 | Mixing disinfectant containing chlorine dioxide and preparing process thereof |
| CN101491257A (en) * | 2009-03-05 | 2009-07-29 | 河北科技大学 | Effervescence type disinfection deodorizer and preparation method thereof |
| CN101695305A (en) * | 2009-10-30 | 2010-04-21 | 张家口市净宇天成化工有限公司 | Solid preparation of chlorine dioxide |
| CN101898078A (en) * | 2010-07-19 | 2010-12-01 | 陈学成 | Slow-release indoor disinfecting and decoration odor removing agent and production method and use method thereof |
| CN102283247A (en) * | 2011-07-23 | 2011-12-21 | 中国农业科学院兰州畜牧与兽药研究所 | Veterinary disinfection powder and preparation method thereof |
| CN104012571A (en) * | 2013-08-29 | 2014-09-03 | 四川省龙天源环保设备制造有限公司 | Chlorine dioxide air disinfectant and preparation method thereof |
| CN204379737U (en) * | 2015-01-09 | 2015-06-10 | 刘婧 | Infectious Disease's sterilizing therapeutic apparatus |
| CN204655472U (en) * | 2015-02-12 | 2015-09-23 | 成都迅德科技有限公司 | Device for fumigation |
| CN204542971U (en) * | 2015-03-02 | 2015-08-12 | 吉林省利泽生物科技有限公司 | A kind of chlorine dioxide device for fumigation |
| CN105381492A (en) * | 2015-12-09 | 2016-03-09 | 深圳万和制药有限公司 | Method and device for releasing chlorine dioxide to space environment |
| CN105963747A (en) * | 2016-04-28 | 2016-09-28 | 兰州泰坦生物科技有限责任公司 | Chlorine dioxide sustained-release device and chlorine dioxide replenisher thereof |
| CN206434708U (en) * | 2016-11-09 | 2017-08-25 | 南宁太空节能科技有限公司 | Anion human body purification barrel |
| CN106818862A (en) * | 2017-01-22 | 2017-06-13 | 清远海贝生物技术有限公司 | A kind of high efficiency chlorine dioxide solution without activation and its production and use |
| CN107018990A (en) * | 2017-04-05 | 2017-08-08 | 南昌大学 | A kind of disinfectant of decomposable asymmetric choice net formaldehyde |
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| Publication number | Publication date |
|---|---|
| CN107593762A (en) | 2018-01-19 |
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