CN1425286A - Disinfectant - Google Patents
Disinfectant Download PDFInfo
- Publication number
- CN1425286A CN1425286A CN 01138339 CN01138339A CN1425286A CN 1425286 A CN1425286 A CN 1425286A CN 01138339 CN01138339 CN 01138339 CN 01138339 A CN01138339 A CN 01138339A CN 1425286 A CN1425286 A CN 1425286A
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- China
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- bactericidal agent
- synergist
- bactericidal
- edta
- active ingredient
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Abstract
The disinfectant is a kind of bacteria-free water solution with effective component tetradecyl dimethyl benzyl ammonium chloride. It also contains synergist didecyl dimethyl ammonium chloride and alkyl dimethyl ammonium oxide. The ratio between the effective component and the synergist is 0.5-1 and the content of the effective component and the synergist is 4-8%. It contains also buffering agent EDTA-EDTA sodium in such content that the pH value is regulated to 7.2-8.2. It may contains small amount of thickening agent, such as ethanol. The disinfectant of the present invention is stable, safe, wide in disinfecting range and high in disinfecting effect.
Description
Technical field
The invention belongs to sterilization articles for use technical field.
Background technology
The cross-infection of bacterium and virus is insoluble always for many years problem in the hospital, although school has taked multiple measure, still has every year many accidents to take place, and not only patient's health is brought very big harm, also causes the tremendous economic loss to school.In public places such as hotel, restaurants, the cross-infection of bacterium, virus is ubiquity also, needs disinfection equally.
Traditional chemical bactericide mostly is chloride, contains iodine, alcohols, aldehydes, peroxide, organic phenolic compounds etc., and environment, apparatus, human body are all had in various degree influence.Along with improving constantly of health of people consciousness, people are more and more higher to the quality requirement of environment, press for the bactericidal agent of a kind of environmental protection, efficient, wide spectrum.
Summary of the invention
The object of the invention is to provide a kind of bactericidal agent of efficient, wide spectrum.
For reaching above-mentioned purpose, the present invention adopts following technical scheme: a kind of bactericidal agent, and it is the aqueous solution, active ingredient is Zephiramine chloride.
Also contain synergist chlorination didecyldimethyl ammonium and alkyl dimethyl amine oxide.
Active ingredient and synergist weight ratio are 1: 1-2, active ingredient and synergist weight content are 4-8%.
Also contain buffer, buffer is an EDTA-EDTA-sodium, and content adds to bactericidal agent PH=7.2-8.2.
Institute's water is a sterile water; Can add a small amount of thickener in the bactericidal agent, as ethanol.
Active ingredient Zephiramine chloride among the present invention adopts tetradecanoic acid and dimethylamine, the benzyl chloride reaction of taking from cocoa butter to generate.At first, identical molar tetradecanoic acid and dimethylamine are placed reactor, under the base catalyst effect, constantly be stirred and heated to 180 ℃, insulation refluxed three hours.Then material is heated to 190 ℃ again, removes unnecessary dimethylamine, naturally cool to 85 ℃.Add equimolar benzyl chloride again, slowly stir, temperature remains in the 85-90 ℃ of scope and continues two hours, gets Zephiramine chloride.
Because raw material is taken from fruit, do not resemble bactericide commonly used now and mostly be chemosynthesis, neither can pollute environment, more can not work the mischief to human body, use fool proof; This bactericidal agent can kill various common pathogenic microorganismss in five minutes, can effectively kill mould, fungi, saccharomycete, bacterium, virus and spore, and bactericidal range is wide, and bactericidal effect is good; This bactericidal agent stable in properties, effect is lasting, is difficult for being subjected to the influence of organic matter acid, alkali and other physics, chemical factor, and apparatus is not had corrosion, and non-stimulated to skin, aqua is convenient to use, and safety non-toxic also is easy to remove residue in the water after the sterilization; Can be used for the sterilization of human body surface, instrument and equipment and operating theater instruments, also can be used for the sterilization in wall, ground, air and the industrialized aquaculture place of public place, especially more obvious to the place bactericidal effect of viral cross-infections such as hospital, hotel.
According to test, (1) bactericidal agent of the present invention does not have corrosion to stainless steel, and the corrosivity of aluminium, copper is mild corrosion, is the moderate corrosion to corrosion of Carbon Steel.(2) bactericidal agent of the present invention was to staphylococcus aureus effect 1 minute, and killing rate reaches 100%.Its 25 times of dilutions were to staphylococcus aureus effect 1 minute, and average kill ratio reaches 99.96%; Act on 5 minutes, killing rate reaches 100%.Its 50 times of dilutions were to staphylococcus aureus effect 3 minutes, and average kill ratio is 99.95%, acts on 7 minutes, and killing rate reaches 100%.(3) bactericidal agent of the present invention was to Escherichia coli effect 1 minute, and killing rate reaches 100%.Its 50 times of dilutions are 99.93% to 1 minute average kill ratio of Escherichia coli effect, act on 7 minutes, and killing rate reaches 100%.(4) bactericidal agent of the present invention was to Candida albicans effect 1 minute, and killing rate reaches 100%.Its 25 times of dilutions were to Candida albicans effect 1 minute, and average kill ratio 99.96% acts on 5 minutes, and killing rate reaches 100%.Its 50 times of dilutions were to Candida albicans effect 3 minutes, and average kill ratio 99.95% acts on 7 minutes, and killing rate reaches 100%.(5) placed 14 days under 54 ℃ of conditions of bactericidal agent of the present invention, its 22.7 times of dilutions were to staphylococcus aureus effect 1 minute, and average kill ratio 99.95% acts on 5 minutes, and killing rate reaches 100%.Relatively preceding with placement, the bactericidal effect no change.(6) bactericidal agent of the present invention can effectively destroy hepatitis B surface antigen to hepatitis B surface antigen effect 5 minutes.(7) neutralizer 1g/L histidine+1g/L cysteine+30ml/L Tween-80+30g/L saponin(e can be effectively in and bactericidal agent of the present invention, neutralizer and neutralized reaction product do not have influence to staphylococcus aureus and medium, and neutralizer and neutralized reaction product have no adverse effects to HBsAg antigenicity and detection.(8) contain 25% calf serum and contain 50% calf serum bactericidal agent bactericidal action of the present invention is not had influence.
Embodiment
Embodiment, a kind of bactericidal agent are got 1.5gEDTA and 0.06gNaOH and are dissolved in a small amount of pure water, adjust PH to 7.2-8.2; Getting Zephiramine chloride 2.46g, chlorination didecyldimethyl ammonium 2.3g, alkyl dimethyl amine oxide 1.44g is being dissolved in respectively in the part pure water under constantly stirring; Above-mentioned solution is fully mixed, and adding the pure water ad pond om is 100g, stir.
Claims (5)
1, a kind of bactericidal agent, the present invention is characterised in that it is the aqueous solution, active ingredient is Zephiramine chloride.
2, bactericidal agent as claimed in claim 1 is characterized in that, also contains synergist chlorination didecyldimethyl ammonium and alkyl dimethyl amine oxide.
3, bactericidal agent as claimed in claim 2 is characterized in that, active ingredient and synergist weight ratio are 1: 1-2, active ingredient and synergist weight content are 4-8%.
As claim 2 or 3 described bactericidal agents, it is characterized in that 4, also contain buffer, buffer is an EDTA-EDTA-sodium, content adds to bactericidal agent PH=7.2-8.2.
5, bactericidal agent as claimed in claim 4 is characterized in that, institute's water is a sterile water; Can add a small amount of thickener in the bactericidal agent, as ethanol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01138339 CN1425286A (en) | 2001-12-19 | 2001-12-19 | Disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01138339 CN1425286A (en) | 2001-12-19 | 2001-12-19 | Disinfectant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1425286A true CN1425286A (en) | 2003-06-25 |
Family
ID=4674543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01138339 Pending CN1425286A (en) | 2001-12-19 | 2001-12-19 | Disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1425286A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100469707C (en) * | 2005-03-11 | 2009-03-18 | 中国石化北京燕化石油化工股份有限公司 | Treatment method of high turbidity high iron circulation cooling water |
| CN103696326A (en) * | 2013-12-10 | 2014-04-02 | 陕西师范大学 | Preservative and antibacterial carbon isolation roll paper |
| WO2019083397A1 (en) * | 2017-10-23 | 2019-05-02 | Общество С Ограниченной Ответственностью "Сан Системз" | Solubilization of chlorhexidine base, anitseptic composition and disinfectant composition |
| RU2689394C1 (en) * | 2018-05-25 | 2019-05-28 | Общество с ограниченной ответственностью "Сателлит" | Water-based disinfectant compositions (versions) and a method for production thereof |
-
2001
- 2001-12-19 CN CN 01138339 patent/CN1425286A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100469707C (en) * | 2005-03-11 | 2009-03-18 | 中国石化北京燕化石油化工股份有限公司 | Treatment method of high turbidity high iron circulation cooling water |
| CN103696326A (en) * | 2013-12-10 | 2014-04-02 | 陕西师范大学 | Preservative and antibacterial carbon isolation roll paper |
| CN103696326B (en) * | 2013-12-10 | 2015-08-19 | 陕西师范大学 | A kind of antiseptic antibacterial type charcoal element is every coil paper |
| WO2019083397A1 (en) * | 2017-10-23 | 2019-05-02 | Общество С Ограниченной Ответственностью "Сан Системз" | Solubilization of chlorhexidine base, anitseptic composition and disinfectant composition |
| RU2689394C1 (en) * | 2018-05-25 | 2019-05-28 | Общество с ограниченной ответственностью "Сателлит" | Water-based disinfectant compositions (versions) and a method for production thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |