CN1414939A - 回收和循环使用d－酒石酸的方法 - Google Patents
回收和循环使用d－酒石酸的方法 Download PDFInfo
- Publication number
- CN1414939A CN1414939A CN00817998.0A CN00817998A CN1414939A CN 1414939 A CN1414939 A CN 1414939A CN 00817998 A CN00817998 A CN 00817998A CN 1414939 A CN1414939 A CN 1414939A
- Authority
- CN
- China
- Prior art keywords
- tartrate
- acid
- amino
- solvent
- waste streams
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 45
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 title claims abstract description 6
- 238000011084 recovery Methods 0.000 title abstract description 6
- 229960001270 d- tartaric acid Drugs 0.000 title abstract 2
- 239000002253 acid Substances 0.000 claims abstract description 11
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 48
- FEWJPZIEWOKRBE-LWMBPPNESA-L D-tartrate(2-) Chemical compound [O-]C(=O)[C@@H](O)[C@H](O)C([O-])=O FEWJPZIEWOKRBE-LWMBPPNESA-L 0.000 claims description 33
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 19
- 239000002699 waste material Substances 0.000 claims description 19
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 16
- 239000002904 solvent Substances 0.000 claims description 16
- 229910052708 sodium Inorganic materials 0.000 claims description 12
- 239000011734 sodium Substances 0.000 claims description 12
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 229910052728 basic metal Inorganic materials 0.000 claims description 7
- 150000003818 basic metals Chemical class 0.000 claims description 7
- 229910052783 alkali metal Inorganic materials 0.000 claims description 5
- 150000001340 alkali metals Chemical class 0.000 claims description 5
- 239000001433 sodium tartrate Substances 0.000 claims description 5
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 229910052700 potassium Inorganic materials 0.000 claims description 4
- 239000011591 potassium Substances 0.000 claims description 4
- 229940095064 tartrate Drugs 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- 238000002425 crystallisation Methods 0.000 claims description 3
- 230000008025 crystallization Effects 0.000 claims description 3
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims description 2
- 125000005233 alkylalcohol group Chemical group 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 2
- 239000011707 mineral Substances 0.000 claims description 2
- 239000001472 potassium tartrate Substances 0.000 claims 1
- 229940111695 potassium tartrate Drugs 0.000 claims 1
- CAOHBROWLMCZRP-UHFFFAOYSA-N 2-amino-2,3-dimethylbutanenitrile Chemical compound CC(C)C(C)(N)C#N CAOHBROWLMCZRP-UHFFFAOYSA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000010815 organic waste Substances 0.000 abstract 1
- 150000003892 tartrate salts Chemical class 0.000 abstract 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 9
- 239000002002 slurry Substances 0.000 description 8
- -1 Imidazolidinone compound Chemical class 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 239000012065 filter cake Substances 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 125000005219 aminonitrile group Chemical group 0.000 description 4
- 235000019524 disodium tartrate Nutrition 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- YAMHXTCMCPHKLN-UHFFFAOYSA-N imidazolidin-2-one Chemical compound O=C1NCCN1 YAMHXTCMCPHKLN-UHFFFAOYSA-N 0.000 description 3
- 229910017053 inorganic salt Inorganic materials 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 238000009333 weeding Methods 0.000 description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-L L-tartrate(2-) Chemical compound [O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O FEWJPZIEWOKRBE-JCYAYHJZSA-L 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- NGPGDYLVALNKEG-UHFFFAOYSA-N azanium;azane;2,3,4-trihydroxy-4-oxobutanoate Chemical compound [NH4+].[NH4+].[O-]C(=O)C(O)C(O)C([O-])=O NGPGDYLVALNKEG-UHFFFAOYSA-N 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 239000002798 polar solvent Substances 0.000 description 2
- AVTYONGGKAJVTE-UHFFFAOYSA-L potassium tartrate Chemical compound [K+].[K+].[O-]C(=O)C(O)C(O)C([O-])=O AVTYONGGKAJVTE-UHFFFAOYSA-L 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 239000012433 hydrogen halide Substances 0.000 description 1
- 229910000039 hydrogen halide Inorganic materials 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000707 stereoselective effect Effects 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17337299P | 1999-12-28 | 1999-12-28 | |
| US60/173,372 | 1999-12-28 | ||
| US47364899A | 1999-12-29 | 1999-12-29 | |
| US09/473,648 | 1999-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1414939A true CN1414939A (zh) | 2003-04-30 |
Family
ID=26869068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00817998.0A Pending CN1414939A (zh) | 1999-12-28 | 2000-12-19 | 回收和循环使用d－酒石酸的方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1242353A1 (fr) |
| CN (1) | CN1414939A (fr) |
| AR (1) | AR027145A1 (fr) |
| AU (1) | AU3160601A (fr) |
| BR (1) | BR0016803A (fr) |
| IL (1) | IL150155A0 (fr) |
| WO (1) | WO2001047856A1 (fr) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101782548A (zh) * | 2009-12-03 | 2010-07-21 | 浙江工业大学 | 一种毛细管电泳拆分2,4-滴丙酸对映体的新方法 |
| CN101906032A (zh) * | 2010-07-14 | 2010-12-08 | 华东理工大学 | 回收和循环使用l-(+)-酒石酸的方法 |
| CN102503810A (zh) * | 2011-11-02 | 2012-06-20 | 浙江科技学院 | 一种回收和循环使用l-酒石酸的方法 |
| CN101643409B (zh) * | 2009-08-31 | 2013-04-24 | 厦门世达膜科技有限公司 | 一种将酒石酸钠转化成酒石酸的生产方法 |
| CN103834964A (zh) * | 2013-12-31 | 2014-06-04 | 浙江工业大学 | 一种毛细管电泳拆分2-甲基-4-氯戊氧基丙酸对映体的方法 |
| CN105152911A (zh) * | 2015-08-17 | 2015-12-16 | 浙江邦成化工有限公司 | 一种酒石酸的回收方法 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4504C1 (ro) * | 2016-04-13 | 2018-03-31 | Общественное Учреждение "Научно-Практический Институт Садоводства И Пищевых Технологий" | Procedeu de obţinere a acidului tartric din tartratul de calciu obţinut din deşeuri vinicole |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE264005C (fr) * | ||||
| US4683324A (en) * | 1982-05-25 | 1987-07-28 | American Cyanamid Company | Process for the resolution of certain racemic amino nitriles |
| DE19819884A1 (de) * | 1998-05-04 | 1999-11-11 | Metallgesellschaft Ag | Verfahren zum Erzeugen von Weinsäure aus einem Kaliumhydrogentartrat enthaltenden Rohmaterial |
-
2000
- 2000-12-19 AU AU31606/01A patent/AU3160601A/en not_active Abandoned
- 2000-12-19 WO PCT/EP2000/012946 patent/WO2001047856A1/fr not_active Application Discontinuation
- 2000-12-19 BR BR0016803-3A patent/BR0016803A/pt not_active Application Discontinuation
- 2000-12-19 EP EP00991215A patent/EP1242353A1/fr not_active Withdrawn
- 2000-12-19 IL IL15015500A patent/IL150155A0/xx unknown
- 2000-12-19 CN CN00817998.0A patent/CN1414939A/zh active Pending
- 2000-12-28 AR ARP000107007A patent/AR027145A1/es unknown
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101643409B (zh) * | 2009-08-31 | 2013-04-24 | 厦门世达膜科技有限公司 | 一种将酒石酸钠转化成酒石酸的生产方法 |
| CN101782548A (zh) * | 2009-12-03 | 2010-07-21 | 浙江工业大学 | 一种毛细管电泳拆分2,4-滴丙酸对映体的新方法 |
| CN101782548B (zh) * | 2009-12-03 | 2013-07-24 | 浙江工业大学 | 一种毛细管电泳拆分2,4-滴丙酸对映体的新方法 |
| CN101906032A (zh) * | 2010-07-14 | 2010-12-08 | 华东理工大学 | 回收和循环使用l-(+)-酒石酸的方法 |
| CN102503810A (zh) * | 2011-11-02 | 2012-06-20 | 浙江科技学院 | 一种回收和循环使用l-酒石酸的方法 |
| CN102503810B (zh) * | 2011-11-02 | 2014-05-21 | 浙江科技学院 | 一种回收和循环使用l-酒石酸的方法 |
| CN103834964A (zh) * | 2013-12-31 | 2014-06-04 | 浙江工业大学 | 一种毛细管电泳拆分2-甲基-4-氯戊氧基丙酸对映体的方法 |
| CN105152911A (zh) * | 2015-08-17 | 2015-12-16 | 浙江邦成化工有限公司 | 一种酒石酸的回收方法 |
| CN105152911B (zh) * | 2015-08-17 | 2017-05-31 | 浙江邦成化工有限公司 | 一种酒石酸的回收方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3160601A (en) | 2001-07-09 |
| BR0016803A (pt) | 2002-09-10 |
| EP1242353A1 (fr) | 2002-09-25 |
| IL150155A0 (en) | 2002-12-01 |
| WO2001047856A1 (fr) | 2001-07-05 |
| AR027145A1 (es) | 2003-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1155554C (zh) | 从发酵肉汤中分离2-酮基-l-古洛糖酸的方法和应用 | |
| CN1414939A (zh) | 回收和循环使用d－酒石酸的方法 | |
| CN101522605B (zh) | 分离4-甲酰基苯甲酸甲酯和对苯二甲酸二甲酯的方法 | |
| US5260482A (en) | Enantiomeric resolution | |
| EP0623108B1 (fr) | Preparation d'acides carboxyliques aliphatiques optiquement actifs | |
| CN1065865C (zh) | 3-羟甲基头孢菌素的溶剂萃取 | |
| EP0623107B1 (fr) | Preparation d'acides carboxyliques aliphatiques optiquement actifs | |
| EP0093511B1 (fr) | Procédé de production d'un acide 2,2-diméthylcyclopropane carboxylique optiquement actif | |
| US6346649B1 (en) | Process for the recovery and recycle of D-tartaric acid | |
| CN1211349C (zh) | 光学活性的α－胺基苯丙酮的制备方法 | |
| EP0437566B1 (fr) | Derives de phenyle-glycine | |
| JPS6323824A (ja) | 酸性α−水素を有するアミンの光学分割およびラセミ化方法 | |
| CN1273607C (zh) | 制备对映体纯对羟基苯甘氨酸的方法 | |
| CN1028361C (zh) | 戊二酸衍生物的制备方法 | |
| CN1166653C (zh) | 苄胺化合物的制造方法 | |
| CN1267334A (zh) | 顺－和反－吡咯并哌啶的外消旋拆分方法 | |
| CN101137602A (zh) | 制备对映异构纯的e-（2s）-烷基-5-卤代戊-4-烯酸及其酯的方法 | |
| CN1282651C (zh) | 包含头孢拉定的酸性水相的稳定方法 | |
| EP0664783A1 (fr) | Resolution enantiomere | |
| CN1609102A (zh) | 一种光学活性氨氯地平的拆分方法 | |
| CN1955185A (zh) | 光学活性的取代氧膦基乙酸盐及其用途 | |
| EP0437567B1 (fr) | Derives de phenyle-glycine | |
| CN1219758C (zh) | 一种光学纯二叔丁基亚磺酸硫酯的制备方法 | |
| JP2002167381A (ja) | （±）−６−ヒドロキシ−２，５，７，８−テトラメチルクロマン−２−カルボン酸の光学分割法 | |
| JPH1121265A (ja) | α−イソプロピル−ｐ−フルオロフェニル酢酸の光学分割方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |