CN1410424A - Extraction technology of new stellerin A - Google Patents
Extraction technology of new stellerin A Download PDFInfo
- Publication number
- CN1410424A CN1410424A CN 02133768 CN02133768A CN1410424A CN 1410424 A CN1410424 A CN 1410424A CN 02133768 CN02133768 CN 02133768 CN 02133768 A CN02133768 A CN 02133768A CN 1410424 A CN1410424 A CN 1410424A
- Authority
- CN
- China
- Prior art keywords
- stellera chamaejasme
- dry powder
- hours
- extraction
- ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000605 extraction Methods 0.000 title claims description 45
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 86
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims abstract description 82
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 41
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 33
- 239000007788 liquid Substances 0.000 claims abstract description 32
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims abstract description 28
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000006243 chemical reaction Methods 0.000 claims abstract description 14
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 230000007062 hydrolysis Effects 0.000 claims abstract description 12
- 238000006460 hydrolysis reaction Methods 0.000 claims abstract description 12
- 239000000284 extract Substances 0.000 claims abstract description 11
- 238000001035 drying Methods 0.000 claims abstract description 9
- 238000000034 method Methods 0.000 claims abstract description 5
- 238000006555 catalytic reaction Methods 0.000 claims abstract description 3
- 241001263604 Stellera chamaejasme Species 0.000 claims description 60
- 239000000243 solution Substances 0.000 claims description 39
- 239000000843 powder Substances 0.000 claims description 33
- 238000002386 leaching Methods 0.000 claims description 24
- 239000000706 filtrate Substances 0.000 claims description 17
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 16
- 238000001556 precipitation Methods 0.000 claims description 16
- 239000003795 chemical substances by application Substances 0.000 claims description 15
- 240000000630 Hedysarum occidentale Species 0.000 claims description 13
- 239000007787 solid Substances 0.000 claims description 11
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 9
- 239000000741 silica gel Substances 0.000 claims description 9
- 229910002027 silica gel Inorganic materials 0.000 claims description 9
- 229960001866 silicon dioxide Drugs 0.000 claims description 9
- 241000196324 Embryophyta Species 0.000 claims description 8
- 239000000178 monomer Substances 0.000 claims description 8
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 8
- 229920002554 vinyl polymer Polymers 0.000 claims description 8
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims description 7
- 238000006206 glycosylation reaction Methods 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims description 7
- 239000012141 concentrate Substances 0.000 claims description 6
- 239000003818 cinder Substances 0.000 claims description 5
- 239000013078 crystal Substances 0.000 claims description 5
- 238000000151 deposition Methods 0.000 claims description 5
- 230000008021 deposition Effects 0.000 claims description 5
- 235000012054 meals Nutrition 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 5
- 239000003513 alkali Substances 0.000 claims description 4
- 230000006837 decompression Effects 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 3
- 238000004821 distillation Methods 0.000 claims description 3
- 230000008014 freezing Effects 0.000 claims description 3
- 238000007710 freezing Methods 0.000 claims description 3
- 238000000926 separation method Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000000047 product Substances 0.000 claims 1
- 241001263603 Stellera Species 0.000 abstract 1
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 229940035423 ethyl ether Drugs 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 229960004756 ethanol Drugs 0.000 description 11
- 238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- 238000005160 1H NMR spectroscopy Methods 0.000 description 1
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- XVMSFILGAMDHEY-UHFFFAOYSA-N 6-(4-aminophenyl)sulfonylpyridin-3-amine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=N1 XVMSFILGAMDHEY-UHFFFAOYSA-N 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 229960000935 dehydrated alcohol Drugs 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- QOLIPNRNLBQTAU-UHFFFAOYSA-N flavan Chemical compound C1CC2=CC=CC=C2OC1C1=CC=CC=C1 QOLIPNRNLBQTAU-UHFFFAOYSA-N 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB021337683A CN1156465C (en) | 2002-09-18 | 2002-09-18 | Extraction technology of new stellerin A |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB021337683A CN1156465C (en) | 2002-09-18 | 2002-09-18 | Extraction technology of new stellerin A |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1410424A true CN1410424A (en) | 2003-04-16 |
CN1156465C CN1156465C (en) | 2004-07-07 |
Family
ID=4747377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB021337683A Expired - Fee Related CN1156465C (en) | 2002-09-18 | 2002-09-18 | Extraction technology of new stellerin A |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1156465C (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100439353C (en) * | 2003-11-20 | 2008-12-03 | 周乐 | Extracting and separating method of langdu root chromone from Stellera chamaejasme L. and its uses |
CN100439362C (en) * | 2003-11-20 | 2008-12-03 | 周乐 | Extracting and separating method of novel langdu root essence B from stellera chamaejasme L and its uses |
CN101987096A (en) * | 2009-07-30 | 2011-03-23 | 株式会社芳珂 | Melanogenesis inhibitor and skin-whitening agent |
CN102060827A (en) * | 2010-12-30 | 2011-05-18 | 苏州瑞蓝博中药技术开发有限公司 | Method for extracting new chamaejasmine B from stellera chamaejasme. L |
CN102078444A (en) * | 2010-12-30 | 2011-06-01 | 苏州瑞蓝博中药技术开发有限公司 | Preparation method of Chinese stellera root total flavonoids |
CN103570660A (en) * | 2012-07-23 | 2014-02-12 | 昆明制药集团股份有限公司 | Method for preparing high-purity scutellarein |
CN105315118A (en) * | 2015-07-10 | 2016-02-10 | 李玉山 | Integrated extracting and separating method for active ingredients of Chinese stellera roots |
CN107743398A (en) * | 2015-04-13 | 2018-02-27 | 韩国科学技术研究院 | The method of the composition and the wound for the treatment of individual for Wound healing and bone regeneration containing root of langdu extract or its fraction |
CN107929785A (en) * | 2017-12-16 | 2018-04-20 | 蒋央芳 | A kind of essential oil and preparation method thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5513258B2 (en) * | 2009-07-30 | 2014-06-04 | 株式会社ファンケル | Melanin production inhibitor and whitening agent |
-
2002
- 2002-09-18 CN CNB021337683A patent/CN1156465C/en not_active Expired - Fee Related
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100439353C (en) * | 2003-11-20 | 2008-12-03 | 周乐 | Extracting and separating method of langdu root chromone from Stellera chamaejasme L. and its uses |
CN100439362C (en) * | 2003-11-20 | 2008-12-03 | 周乐 | Extracting and separating method of novel langdu root essence B from stellera chamaejasme L and its uses |
CN101987096A (en) * | 2009-07-30 | 2011-03-23 | 株式会社芳珂 | Melanogenesis inhibitor and skin-whitening agent |
CN101987096B (en) * | 2009-07-30 | 2013-07-10 | 株式会社芳珂 | Melanogenesis inhibitor and skin-whitening agent |
CN102060827A (en) * | 2010-12-30 | 2011-05-18 | 苏州瑞蓝博中药技术开发有限公司 | Method for extracting new chamaejasmine B from stellera chamaejasme. L |
CN102078444A (en) * | 2010-12-30 | 2011-06-01 | 苏州瑞蓝博中药技术开发有限公司 | Preparation method of Chinese stellera root total flavonoids |
CN103570660A (en) * | 2012-07-23 | 2014-02-12 | 昆明制药集团股份有限公司 | Method for preparing high-purity scutellarein |
CN103570660B (en) * | 2012-07-23 | 2015-09-09 | 昆明制药集团股份有限公司 | A kind of method preparing breviscapine B aglycone |
CN107743398A (en) * | 2015-04-13 | 2018-02-27 | 韩国科学技术研究院 | The method of the composition and the wound for the treatment of individual for Wound healing and bone regeneration containing root of langdu extract or its fraction |
US11541096B2 (en) | 2015-04-13 | 2023-01-03 | Korea Institute Of Science And Technology | Composition for wound treatment containing extract of Stellera chamaejasme or fraction thereof and method for treating wound of subject |
CN105315118A (en) * | 2015-07-10 | 2016-02-10 | 李玉山 | Integrated extracting and separating method for active ingredients of Chinese stellera roots |
CN107929785A (en) * | 2017-12-16 | 2018-04-20 | 蒋央芳 | A kind of essential oil and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
CN1156465C (en) | 2004-07-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4038481A (en) | Method for treatment of corn hulls | |
CN1156465C (en) | Extraction technology of new stellerin A | |
WO2015010497A1 (en) | Method for preparing lycium ruthenicum polysaccharide | |
CN109608559A (en) | A method of extracting active polysaccharide from seaweed | |
CN102060933A (en) | Method for extracting and separating in-vivo water-soluble polysaccharide from old water shield leaves | |
CN109134680B (en) | Extraction and purification method of fucoidin and application thereof | |
CN111019015A (en) | Preparation method of high-purity water-insoluble xylan | |
CN104387483A (en) | Method for extracting peony polysaccharides from peony cake by use of biological enzymes | |
CN1359905A (en) | Process for extracting licoflavone, lycyrrhizic acid and licopolyose from liquorice root | |
CN113980153B (en) | Method for extracting high-viscosity peach gum polysaccharide | |
CN1206245C (en) | Algae extracting process | |
CN1194983C (en) | Process for extracting anthoxyanin from cowbeery | |
CN105463040A (en) | Method for raising yield of xylooligosaccharide | |
CN111187328B (en) | Method for preparing mogrol | |
CN107857825A (en) | A kind of extracting method of radix tetrastigme polysaccharide | |
CN102174052B (en) | Method for extracting and refining ginkgolide | |
CN111777656A (en) | Method for extracting astragaloside from fresh astragalus | |
CN114539132B (en) | DNJ method for hydrothermally acid-controlled alcohol extraction of mulberry leaves | |
CN109053517B (en) | Method for extracting lutein from marigold | |
CN108530506B (en) | Method for extracting baicalin by low-temperature fermentation and microwave water circulation | |
CN113773360A (en) | Method for separating mogrol from momordica grosvenori | |
CN103483404A (en) | Method for extracting and purifying hesperidin from orange residues | |
CN102086236A (en) | Method for extracting and separating in vivo alkali-soluble polysaccharide from old water shield leaves | |
CN1235852C (en) | Method for extracting curcumin from peltate yam | |
CN104045624A (en) | Highly pure nicotine preparation method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C57 | Notification of unclear or unknown address | ||
DD01 | Delivery of document by public notice |
Addressee: Zhang Jieke Document name: payment instructions |
|
ASS | Succession or assignment of patent right |
Owner name: GANSU GUOLI BIO-TECHNOLOGY DEVELOPMENT CO., LTD. Free format text: FORMER OWNER: ZHANG JIEKE Effective date: 20070202 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20070202 Address after: Twenty building, International Trade Building or Cetra Building, No. 258, Qingyang Road, Chengguan District, Gansu, Lanzhou, 730030 Patentee after: Gansu Guoli biological science and Technology Development Co Ltd Address before: 610072, Chengdu, Sichuan province Jinli Street West Road, No. 78 force industry Co., Ltd. Patentee before: Zhang Jieke |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040707 Termination date: 20140918 |
|
EXPY | Termination of patent right or utility model |