CN1405294A - Wine for modulating immune from gene of ancient organism at deep sea and its production method - Google Patents

Wine for modulating immune from gene of ancient organism at deep sea and its production method Download PDF

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CN1405294A
CN1405294A CN 02139247 CN02139247A CN1405294A CN 1405294 A CN1405294 A CN 1405294A CN 02139247 CN02139247 CN 02139247 CN 02139247 A CN02139247 A CN 02139247A CN 1405294 A CN1405294 A CN 1405294A
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wine
microalgae
potential energy
immunoregulation
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CN1203167C (en
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陈克拉
易乾东
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Abstract

The invention refers to a kind of immune regulating wine which is made up from ocean biology gene, it includes wine and tiny alga. The manufacturing method is: the wine and tiny alga or the extracted materials are bleneded through potential energy activating under 5-45 degree C and ordinary pressure according to the proportion, realizes the biological transition of edible wine and tiny alga, then through intimidating cultivating, and it is secondary potential energy activated, itself carriers on gourmet powder yeast fixing, finally examining and packing, then the product is obtained. The invention can make the cell restore DNA by itself, enhance the growing and error correcting ability of DNA, maintain its energy.

Description

Deep-sea biological gene in time immemorial immunoregulation wine and production method thereof
Technical field
The present invention relates to inebriant food, particularly a kind of inebriant food and production method thereof with nourishing function.
Background technology
Wine is the normal drinking beverage of people, drinks production is to be raw material with starch or glucide mostly, obtain through the mediation of fermenting, distill, blend under certain condition by adding microorganism such as distiller's yeast, yeast etc., the product main component that obtains in this way is alcohol, water and a spot of fusel, aldehyde and organic substance, because it has the mouthfeel of unique aromatic and stimulation, many people produce the hobby effect to it, thereby be that the phenomenon of pleasure happens occasionally to drink, the somebody also indulges in excessive drinking and becomes second nature, and other people are worked the mischief.And meals alcohol is to human liver, kidney, toxic side effect that cardiovascular and cerebrovascular produces and ill-health influence this disastrous effect and exist all the time, according to medical literature, after a people drinks, 80% alcohol is absorbed by duodenum, all the other are absorbed by stomach, enter other tissue by blood and liver then, the intravital alcoholdehydrogenase of people constantly resolves into acetaldehyde with alcohol in liver, the acetaldehyde that decomposition is come out is again by the rapid acidifying of aldehyde dehydrogenase, and further resolve into water and carbonic acid gas, in this biochemical reaction process, force body secretion suprarenin, make the maincenter vasoconstriction, palpitating speed, quicken the metabolism of hematin, impel liver and gall red pigment and transaminase to rise, the level that causes liver particle cell hemochrome P450 reduces, Selenoperoxidase first mate in blood plasma and the liver is descended, the intravital neutrophil of machine is being engulfed and is being killed in the process of pathogenic agent, increased the formation of hydrogen peroxide, impel neutrophil to produce hydrogen peroxide, cause hydrogen peroxide to leukocytic destruction, and the increment of reduction body endolymph cell, reduce lymphocytic engulfing and sterilizing activity, increased the lipid peroxide MDA content, strengthened the lipoid substance peroxidation, reduce red corpuscle resistive to hydrogen peroxide oxidative damage ability, caused SiO 2The infringement of pair cell, influence amino acid whose metabolism of sulphur and cellular respiration especially, cause the activity tenesmus of liver cell phosphodiesterase, and impel canceration factor cGMP (cyclic guanosine monophosphate) to increase the matter division, cause insatiable hunger to close lipid acid and damage, activated oncogene impels antioncogene to lose, the growth of inhibition antioncogene is sound and duplicate error correcting capability, causes sharply necrosis of cell, causes hepatic necrosis and tumor and pancreatic functions imbalance etc.
According to " news morning newspaper " investigation report: " only 10 years; the alcohol dependence morbidity of China has risen 3.7 times unexpectedly; alcoholist's predicted life on average is lower than 53 years old (lack 13 years old in 66 years old than global mean lifetime) (world population mean lifetime in 2000 is 66 years old; developed country and regional average out to 76 years old; developing countries and regions's average out to 64 years old (from United Nations Statistical Commission's statistics in 2000; announced on September 25th, 2002 by Xinhua News Agency)), it was important and be badly in need of the outstanding public health problem of solution to have become 21 century thus." hold in Shanghai, and exemplified detrimentally affect and the toxic side effect of a series of meals alcohol to HUMAN HEALTH on September 14th, 2002 " first in China drinks and healthy international symposium ".In symposial, above-mentioned information has been announced at Shanghai health education and health-promoting center.Shanghai City relevant department of the People's Government has formulated one " the healthy intervention plan of drinking ".Health ministry is also reacted, solving meals alcohol and the outstanding public health problem of being badly in need of solution important to the ill-health influence of human body and toxic side effect this 21 century as the important historical agenda.
The up-to-date report of of the 14 world health work summit meeting of in September, 2002 World Health Organization (UN/WHO) shows: (be air, drinking-water, food and bad life style and life behavior by " environment and mode of life disease " caused ratio up to 80% in cardiovascular and cerebrovascular and the cancer patient.As smoking, indulge in excessive drinking, breathe waste gas (oil smoke in the vehicle exhaust of ubiquity and the cooking etc.)).
Alcoholic liver, kidney early ageing, liver cirrhosis, liver cancer and cardiovascular and cerebrovascular diseases and excessive drinking have direct relation, and it is important and be badly in need of the outstanding public health problem that solves that excessive drinking has become 21 century to the toxic side effect of human liver, kidney, heart function and adverse health influence.
Among the people have steeped some Chinese herb medicines with steeping in wine in China, with the tradition for the treatment of disease or taking nourishing food to build up one's health, this is because of the be dissolved with better effects of ethanol to pharmaceutical cpd, drunk this class medicinal liquor, medicine can enter its hetero-organization by stomach and intestine to blood and liver rapidly, thus some disease take herbal wine can be effective in cure.But the part active substance is destroyed by alcohol in the process in the wine because the effective ingredient of Chinese medicine is dissolved in, thereby gi tract are obviously reduced to the absorption of calcium, vitamins D, make generation adverse consequencess such as amyocardia, the elderly who particularly suffers from bronchial asthma, consequence is more feared, because the sulfurous acid material in the system wine can cause asthma attack and increase the weight of the state of an illness.Therefore can fundamentally solve meals alcohol to the toxic side effect of functions such as human liver, kidney, heart with to the detrimentally affect of health, can keep traditional characteristics quality and aromatic the drinking of good mouthfeel again, provide a kind of brand-new quality of life and health care imperative to the mankind.
Little algae also claims unicellular algae, promptly just can distinguish the small algae monoid of its form at microscopically.The microalgae species distribution is very wide, and discovery is all arranged in soil, marsh, fresh water, hot spring.Be not suitable for other biological extreme environment at some, as equally also growing in the lake of high salinity degree, but the little algae with the deep-sea is best, it contains abundant quality protein, unsaturated fatty acids, multiple amino acids and abundant VITAMIN, trace element, carotene, algocyan, ferment and polysaccharide etc. without any pollution.Little algae at deep-sea is species the most ancient on the earth, and the survival in more than 30 hundred million years of tool has history, and stable biological framework composition and extremely prosperous and powerful vitality are arranged.The mystery in tens years is evolved, make it have extremely strong life long-lived bioinformation of heredity and high antiviral activity, through measuring with the modern biochemistry method, mainly contain glutathione peroxidase and promote the factor, can promote reinforcement increase function to organize the glutathione peroxidase in blood plasma and the liver, improve the activity of blood person of low position body plate GSH-Px, thereby make B, T lymphopoiesis improve immunizing power.In addition, because little algae (as spirulina, Dunaliella salina etc.) cell walls is cellulose hardly, thereby has a higher digestibility, its digestibility can be up to 93%: and cholesterol level is but very low, just because of this, it is recommended as " human optimal protective foods of 21 century " by the World Food Programme of United Nations.Can utilize little algae to be meant batch production production or have application prospect, can be with a large amount of fronds of cultivating of biotechnology whole or frond contained certain or some composition by kind that people utilized.The research of algae started from for 18 end of the centurys, and the cultivation of unicellular algae started from for 19 beginnings of the century.China Zhu Shuping professor cultivates into single-cell algae nineteen forty-two, and it successively substitutes grain, beverage.The eighties people to have understood little algae be very abundant high value chemical and medicine source, so be that healthcare products, food, the additive of raw material constantly occurs with little algae.At present, the algae bio Study on Technology is developed various places all over the world, algae production company emerge in multitude has important directive significance but therefore understand kind, ecology, the distribution utility value that can utilize little algae extensively and profoundly and use to the production of little algae and for the mankind provide green food.But what people utilized at present all is former algae substances, and the material that extracts from algae is in conceptual phase.
Technology contents
How better microalgae material or microalgae extract and modern foodstuffs industry are combined, make food a kind of health, popular, making this ancient marine organisms performance of being rich in nutrition of little algae that effect should be arranged, is food scientist's research topic.The inventor is through years of researches and exploration, found the novel method of utilizing microalgae material or microalgae extracting substance and drink food to combine, wine is reduced the side effect degree of human body, make the multiple function that helps HUMAN HEALTH of microalgae material or microalgae extracting substance demonstrate fully out again, started a kind of new variety of food.On the characteristic quality that ensures traditional liquor and good mouthfeel and aromatic basis, fundamentally solved meals alcohol to the toxic side effect of human liver, kidney, heart function with to the detrimentally affect of health with its original glamour, " alcoholic liver ", kidney early ageing, liver cirrhosis have been solved completely, the prevention and the deep layer immunoregulation that comprise liver cancer, safeguard its vigor health, with its brand-new and vigorous modernized vigor, provide a kind of brand-new quality of life and health care support to the mankind, bringing up the wine with sense of the times of new generation and international competitiveness is new family.
Technical scheme of the present invention is as follows:
Deep-sea biological gene in time immemorial immunoregulation wine comprises finished wine and microalgae material or microalgae extracting substance, and its composition and content are microalgae material or the 100 μ g-1000mg microalgae extracting substance that every liter of finished wine contains 600mg-10g.
More than said microalgae material be selected from the chlorella that from the ocean, obtains, the purple algae of phaeodactylum tricornutum, Porphyridium cruentum, salt and give birth to small green alga, Isochrysis galbana, diatom, spirulina and Dunaliella salina.
More than the aquatic foods product that obtain for little algae of directly obtaining from benthos or through artificial culture of said microalgae material or the former algae crystalline substance that obtains of fragmentation after drying.
More than the effective constituent of said microalgae extracting substance be that the Agifutol peroxidase promotes the factor, from little algae, extract solvent-extraction process or biological enzyme extraction method that method that the Agifutol peroxidase promotes the factor can be routinely.
More than said finished wine can be liquor or fruit wine, drinks or the mixture that wherein can select for use rice wine, Kaoliang spirit, cassiri, coarse cereals wine, bent wine, cellar for storing things wine, edible ethanol blended liquor, grape wine, hard cider, sucrose wine or other grain, fruit, starch to brewage.
The production method of marine organisms immunoregulation wine is: at first produce mother liquor, again with the mother liquor dilution proportion, carry out 1-6 hour secondary potential energy and activate, close typing through 24-72 hour monosodium glutamate ferment again, test package obtains product.
1, the production of mother liquor: 5 ℃-45 ℃ temperature, under the atmospheric pressure environment condition, with selected ethanol concn, mouthfeel and aromatic finished wine, carrying out equilibrium with microalgae material or microalgae extracting substance through 1-3 hour potential energy activation condition mixes, realize its meals alcohol and microalgae material or the good bio-transformation of microalgae extracting substance bonded, and again through 1-6 hour the cultivation of coercing, fully the molecule power of assurance meals alcohol and microalgae material or the good bio-transformation of microalgae extracting substance bonded and activity and energy are given, ensure its useful effect effect, become product mother liquid.
2, finished product production: according to the ratio design requirements of mother liquor through 1-6 hour secondary potential energy activation condition, keep its biological activity and energy to give, press and dilution proportion, utilize the savings of its secondary activating energy, make the monosodium glutamate ferment that himself carried out under the normal temperature and pressure envrionment conditions 24-72 hour close typing, test package obtains product.
More than said coerce to cultivate be: the closed photo bioreactor (colour temperature 2200K-5200K) that utilizes 10-100 to rise under 5 ℃-45 ℃ temperature, atmospheric pressure environment condition is created the illumination bio-transformation side of body that adapts to and is helped condition, implement 1-6 hour photoautotrophy, force the molecule growth power that improves meals alcohol and microalgae material or microalgae extracting substance bonded inverting biological, strengthen the molecular biological activity that keeps microalgae material or microalgae extracting substance, make each bioactive molecule can both give vigor, ensure its useful effect effect.
More than said potential energy activate the following several mode that comprises:
1, under 5 ℃-45 ℃ temperature, atmospheric pressure environment condition, selected ethanol concn and mouthfeel and aromatic finished wine are contained in the container of the sealing that 10-100 rises with microalgae material or microalgae extracting substance, the potential energy that carries out more than 50 times with the frequency of 20HZ-60HZ vibrates, each time is 1-5 minute, promptly more than 1 hour, make fully that meals alcohol and microalgae material or microalgae extracting substance are balanced to be mixed and give molecular energy, keep its biological activity, ensure its useful effect.
2, the ethanol concn that will select under 5 ℃-45 ℃ temperature, atmospheric pressure environment condition and mouthfeel and aromatic finished wine are sealed stirring rapidly with microalgae material or microalgae extracting substance and (are for example used stirrer, selecting speed is 3-500 revolutions per second, rotating in every 2-10 minute stir conversion once, the time is 1-4 hour) meals alcohol is mixed with microalgae material or the equilibrium of microalgae extracting substance, and give molecular energy, keep its biological activity, ensure its useful effect.
3, will reinstate press pump through selected ethanol concn and mouthfeel and aromatic finished wine and microalgae extract one seals and beats to eminence after mixing, beam is in the container of certain potential energy difference then, potential energy difference 1-8 meter per second, circulation beam time 1-6 hour, make that meals alcohol and microalgae material or microalgae extracting substance are balanced to be mixed and give molecular energy, keep its biological activity, ensure its useful effect.
Compare with fruit wine with existing common white spirit with the immunoregulation wine that the marine organisms gene of the present invention's production is made, its outstanding substantive distinguishing features and obvious improvement is:
1, meals alcohol is to human liver, kidney, cardiovascular can produce toxic side effect and ill-health is influenced, and after adding microalgae material or microalgae extract, alcohol is alleviated greatly to the harm of human body, even it has kept the original hobby characteristic quality and the good mouthfeel and aromatic of traditional liquor (or fruit wine), again from efficiently solving for thousands of years meals alcohol in essence to human liver, kidney, the toxic side effect of cardiovascular and cerebrovascular and healthy effect, outstanding public health problem in this global drinking, particularly for promoting alcoholic liver, active and effective effect has been played in the control of fatty liver and liver cancer, and will impel traditional wine already to stride forward healthy new era in century, enriched the intension of traditional liquor (or fruit wine) function, fully promoted core competitiveness and competitive edge and the market atmosphere of national wine in the world market.
2, above-mentioned we mention, little algae not only has abundant nutritive value, and be the resource of very abundant additional high value biochemical drug, contain some nutritive ingredient that is difficult to from other biological, obtain in the frustule, as unsaturated fatty acids, astaxanthin, P-carotene and multiple biologically active substance, have dietotherapy and pharmaceutical use.The polyunsaturated fatty acid (PUPA) that utilizes little algae to produce at present, as gamma-linolenic acid, EPA (DHA (docosahexaenoic acid)), can prevent and treat cardiovascular disorder, cancer, regulate the unify function of vision system of central nervous system, wherein the unsaturated fatty acids in the spirulina mainly is linolic acid and gamma-linolenic acid, the two can reduce the effect of blood plasma cholesterol level, particularly gamma-linolenic acid, and its effect is the former 170 times.Find at present the breeding that gamma-linolenic acid can also anticancer, use Dunaliella salina, spirulina obtains A-carotene, clinical confirmation is added gamma carotene and can successfully be treated genetic photosensitive disease.It is a vitamin A precursor, many foods can prevent and effect a radical cure vitamin(e) A deficiency, simultaneously it have anticancer, prevention is cardiovascular, glaucoma and immunologic function, the P-Radix Dauci Sativae is removed the antioxygenation of oxyradical mutually in addition, can prevent aging, prevention and adjuvant therapy of tumors.Astaxanthin also belongs to same carotenoid, it can extract from Haematocoocus Pluvialls, and it has very strong anti-oxidant function, can eliminate the free radical that is produced by uviolizing in the body, regulate and reduce these injuries that caused by photochemistry, the skin carcinoma that ultraviolet ray is caused has good result of treatment.Water-soluble spirulina glycoprotein all has radioprotective, anti-oxidant, enhance immunity power, promote lymphocyte transformation and suppress effects such as waterlogging cell proliferation, Phycocyanins, C-wherein is used as tracer agent and immunofluorescence agent and antitumor drug on clinical medicine, the chlorella cells digestibility is lower, can be used as a kind of food fiber and treats gastrointestinal system disorder.
The microalgae material contains chlorophyll more, after they are taken in by human body, can be converted into protoheme soon, and improve the protoheme level of body fast, thereby improve the function of blood circulation, this treatment to heart trouble, hypertension, cardiovascular system diseases is helpful: spirulina and enzymolysis product thereof, but the also metabolism of skin irritation, prevent the keratinization of skin, but the activeconstituents accelerating wound healing of little algae that has such as spirulina.
After microalgae material or microalgae extracting substance enter the human intestines and stomach in addition, can be by profitable strain utilizations such as bifidus bacillus, lactobacilluss, and the meta-bolites of profitable strain can promote its digestion, growth and propagation, thereby stimulated the intestine immunity organ growth, improve the activity of scavenger cell, improve the body antibody horizontal, microalgae Immune Regulatory Effects of Substance testing identity, it has obvious raising antibody forming cell's number and NK cytoactive, the effect of raise immunity.And, can improve nutritional status by reducing the vivotoxin level, help liver cell growth, improve body immunity etc. and play provide protection to liver, auxiliary improvement hepatopathy symptom.Cause the symptom of flora imbalance for side reaction with chemistry, radiation, immunosuppressant therapy, as appetite lower, weak, white corpuscle juice number degradation down, it can be improved, disease resistance enhancemen.
3, the present invention be advantageous in that, it can organize the glutathione peroxidase in blood plasma and the liver by promoting reinforcement increase function, improve the activity of hematoblastic GSH-PX, enhancing body I type 5 takes off iodine enzyme (ID1) vigor, make in the hypophysis brain II type take off that iodine enzyme (ID2) is active to be promoted, make bone-marrow-derived lymphocyte, the increment of T lymphocyte, and impel growth hormone (HGH) secretion to increase, significantly reduce liver and gall red pigment and transaminase and lipid peroxide MDA content, fully strengthen the erythrocyte resistance of oxidation, remove ammonia free radical and lipid free radical, and the generation of inhibition lipid free radical, impel the activity of liver cell phosphodiesterase, the metabolism of the anticancer factor cAMP of efficient hardening (cyclic nucleotide) makes cAMP concentration lift-rising, activates P53 genetic expression, suppress bcl-2 genetic expression, start the death of cancer cells active process, thereby make cancer cell-apoptosis.Protect the necrosis and the canceration of its cell membrane function and prevention cell, promote that the growth of antioncogene P53 is sound, impel body cell to carry out self DNA reparation, the growth of reinforcement DNA is sound and duplicate error correcting capability, safeguards its vigor health.
Embodiment
Embodiment one:
Get ethanol concn and be 28 ° 10 liters in rice wine, the brilliant 8g of spirulina, 25 ℃ of temperature environments, normal pressure, potential energy vibration.Rice wine is contained in 50 liters the closed container with spirulina extract, carry out 100 times with the frequency of 50HZ, each time is 2 minutes, totally 3 hours potential energy vibration, the equilibrium of rice wine and spirulina extract is mixed, give energy and promptly finish potential energy activation first, carry out 2 hours the cultivation of coercing again, mother liquor, activate (program still) in 1: 100 ratio through 3 hours secondary potential energy then, balanced once more mix and utilize the savings of secondary potential energy activated energy to make himself under the normal temperature and pressure envrionment conditions, to carry out the monosodium glutamate ferment closed 36 hours, promptly obtain product.
Embodiment two:
Get ethanol concn and be 28 ° 10 liters in rice wine, spirulina extract 2mg, 25 ℃ of temperature environments, normal pressure, potential energy vibration.Rice wine is contained in 50 liters the closed container with spirulina extract, carry out 100 times with the frequency of 50HZ, each time is 2 minutes, totally 3 hours potential energy vibration, the equilibrium of rice wine and spirulina extract is mixed, give energy and promptly finish potential energy activation first, carry out 2 hours the cultivation of coercing again, mother liquor, activate (program still) in 1: 100 ratio through 3 hours secondary potential energy then, balanced once more mix and utilize the savings of secondary potential energy activated energy to make himself under the normal temperature and pressure envrionment conditions, to carry out the monosodium glutamate ferment closed 36 hours, promptly obtain product.
Embodiment three:
With ethanol concn is 45 ° 50 liters of bent wine, chlorella extract 10mg, 10 ℃ of temperature environments, normal pressure.Bent wine stirred rapidly with chlorella extract (stirring velocity is 200 revolutions per seconds, rotating in per 5 minutes exchange once, time is 1 hour) bent wine and the abundant equilibrium of chlorella extract are mixed, give energy and promptly finish potential energy activation first, carry out 1 hour the cultivation of coercing again, promptly become mother liquor, activate (program still) in 1: 50 ratio through 1 hour secondary potential energy then, balanced once more mix and utilize its secondary potential energy activated energy savings to make himself under the normal temperature and pressure envrionment conditions, to carry out the monosodium glutamate ferment closed 48 hours, promptly obtain product.
Embodiment four:
Get 100 liters of odor type cellar for storing things wine, Dunaliella salina 200g, 8 ℃ of temperature environments, normal pressure.To store wine and Dunaliella salina extract one reinstates press pump sealing and mixes the back and beat the eminence to 10m, keep potential energy difference 4 meter per seconds then, the circulation beam made cellar for storing things wine and abundant balanced mixing of Dunaliella salina extract in 4 hours, give energy and promptly finish potential energy activation first, carry out coercing in 2 hours cultivation again, promptly become mother liquor, activate (program still) in 1: 1000 ratio through 2 hours secondary potential energy then, balanced once more mix and utilize its secondary potential energy activated energy savings to make himself to carry out the monosodium glutamate ferment at normal temperatures and pressures closed 72 hours, promptly obtain product.
Embodiment five:
Get ethanol concn and be 12 ° 20 liters of grape wine, the brilliant 50g of diatom, 30 ℃ of temperature, normal pressure.Grape is contained in 100 liters the closed container with the diatom extract, carry out 200 times with the frequency of 25HZ, each time is 2 minutes, totally 6 hours potential energy vibration, the equilibrium of grape wine and diatom extract is mixed, give energy, promptly finishing first, potential energy activates, carry out 3 hours the cultivation of coercing again, promptly become mother liquor, activate (program still) in 1: 500 ratio through 4 hours secondary potential energy then, balancedly once more mix the energy savings that also utilize secondary activating, make and himself under normal temperature and pressure conditions, carry out plain ferment and closed 48 hours, promptly obtain product.
Embodiment six:
Get ethanol concn and be 12 ° 20 liters of grape wine, diatom extract 2mg, 30 ℃ of temperature, normal pressure.Grape is contained in 100 liters the closed container with the diatom extract, carry out 200 times with the frequency of 25HZ, each time is 2 minutes, totally 6 hours potential energy vibration, the equilibrium of grape wine and diatom extract is mixed, give energy, promptly finishing first, potential energy activates, carry out 3 hours the cultivation of coercing again, promptly become mother liquor, activate (program still) in 1: 500 ratio through 4 hours secondary potential energy then, balancedly once more mix the energy savings that also utilize secondary activating, make and himself under the normal temperature and pressure envrionment conditions, carry out plain ferment and closed 48 hours, promptly obtain product.
Embodiment seven:
Get ethanol concn and be 10 ° 5 liters of hard ciders, Porphyridium cruentum extract 5mg, 40 ℃ of temperature environments, normal pressure.Hard cider stirred rapidly with the Porphyridium cruentum extract (stirring velocity is 100 revolutions per seconds, rotating in per 2 minutes exchange once, time is 2 hours) hard cider and the equilibrium of Porphyridium cruentum extract are mixed, give energy and promptly finish potential energy activation first, carry out 4 hours the cultivation of coercing again, promptly become mother liquor, and then activate (program still) through 6 hours secondary potential energy in 1: 200 ratio, the balanced once more energy savings that mix and utilize secondary activating, make and himself under the normal temperature and pressure envrionment conditions, carry out plain ferment and closed 24 hours, promptly obtain product.
Embodiment eight:
Get ethanol concn and be 8 ° 500 liters of Chinese goosebeery wine, the purple algae extract of phaeodactylum tricornutum 5g, 45 ℃ of temperature environments, normal pressure.The purple algae extract one of Chinese goosebeery wine and phaeodactylum tricornutum is reinstated press pump to mix the back and beats to 5 meters eminences, keep potential energy difference 2 meter per seconds then, circulation beam 2 hours, make abundant balanced mixing of the purple filling of Chinese goosebeery wine and phaeodactylum tricornutum extract, give energy and promptly finish potential energy activation first, carry out 3 hours the cultivation of coercing again, mother liquor, activate (program still) in 1: 20 ratio through 1 hour secondary potential energy then, the balanced once more energy savings that mix and utilize secondary activating, make and himself under the normal temperature and pressure envrionment conditions, carry out plain ferment and closed 72 hours, promptly obtain product.

Claims (10)

1, a kind of deep-sea biological gene in time immemorial immunoregulation wine, it is characterized in that: it comprises finished wine and microalgae material or microalgae extracting substance, and its composition and content are microalgae material or the 100 μ g-1000mg microalgae extracting substance that every liter of finished wine contains 600mg-10g.
2, deep-sea according to claim 1 biological gene in time immemorial immunoregulation wine is characterized in that: said microalgae material is selected from the purple algae of chlorella, phaeodactylum tricornutum, Porphyridium cruentum, the salt that obtain and gives birth to small green alga, Isochrysis galbana, diatom, spirulina and Dunaliella salina from the ocean.
3, deep-sea according to claim 1 biological gene in time immemorial immunoregulation wine is characterized in that: aquatic foods product that said microalgae material obtains for little algae of directly obtaining from benthos or through artificial culture or the former algae crystalline substance that obtains of fragmentation after drying.
4, deep-sea according to claim 1 biological gene in time immemorial immunoregulation wine, it is characterized in that: the effective constituent of said microalgae extracting substance is that the Agifutol peroxidase promotes the factor, and promptly the Agifutol peroxidase that extracts from little algae of solvent extraction or biological enzyme extraction method promotes the factor routinely.
5, deep-sea according to claim 1 biological gene in time immemorial immunoregulation wine, it is characterized in that: said finished wine is liquor or fruit wine, is selected from drinks or mixture that rice wine, Kaoliang spirit, cassiri, coarse cereals wine, bent wine, cellar for storing things wine, edible ethanol blended liquor, grape wine, hard cider, sucrose wine or other grain, fruit, starch are brewageed.
6, the production method of a kind of deep-sea as claimed in claim 1 biological gene in time immemorial immunoregulation wine, it is characterized in that: at first produce mother liquor,, carry out 1-6 hour secondary potential energy and activate again with the mother liquor dilution proportion, close typing through 24-72 hour monosodium glutamate ferment again, test package obtains product.
7, the production method of deep-sea according to claim 5 biological gene in time immemorial immunoregulation wine, it is characterized in that: the production of mother liquor is under the temperature, atmospheric pressure environment condition at 5 ℃-45 ℃, at closed photo bioreactor, among the colour temperature 2200K-5200K, with selected ethanol concn, mouthfeel and aromatic finished wine, carry out equilibrium with microalgae material or microalgae extracting substance through 1-6 hour potential energy activation condition and mix, and, become product mother liquid again through 1-6 hour the cultivation of coercing.
8, the production method of deep-sea according to claim 5 biological gene in time immemorial immunoregulation wine, it is characterized in that: potential energy activated mode is included under 5 ℃-45 ℃ the temperature, atmospheric pressure environment condition, selected ethanol concn and mouthfeel and aromatic finished wine are contained in the container of the sealing that 10-100 rises with microalgae material or microalgae extracting substance, carrying out each time with the frequency of 20HZ-60HZ is 1-5 minute, the potential energy vibration more than 50 times.
9, the production method of deep-sea according to claim 5 biological gene in time immemorial immunoregulation wine, it is characterized in that: potential energy activated mode is included in the ethanol concn that will select under 5 ℃-45 ℃ the temperature, atmospheric pressure environment condition and mouthfeel and aromatic finished wine and stirred rapidly 1-4 hour with microalgae material or microalgae extracting substance, and speed is 3-500 revolutions per second.
10, the production method of deep-sea according to claim 5 biological gene in time immemorial immunoregulation wine, it is characterized in that: potential energy activated mode comprises seals and beats to eminence after mixing reinstate press pump through selected ethanol concn and mouthfeel and aromatic finished wine and microalgae material or microalgae extracting substance one, beam is in the container of certain potential energy difference then, potential energy difference 1-8 meter per second, the circulation beam time is 1-6 hour.
CN 02139247 2002-11-03 2002-11-03 Wine for modulating immune from gene of ancient organism at deep sea and its production method Expired - Fee Related CN1203167C (en)

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CN102337196A (en) * 2011-09-08 2012-02-01 宁波红龙生物科技有限公司 Haematococcus alcoholic drink and preparation method thereof
CN102512501A (en) * 2012-01-01 2012-06-27 山东大学威海分校 Preparation method of compound Chinese magnoliavine fruit preparation and antioxidant activity thereof
CN102851177A (en) * 2012-09-24 2013-01-02 朱劲荣 Glutinous rice/chlorella mixed and brewed selenium-rich yellow wine
CN102876544A (en) * 2012-10-26 2013-01-16 上海麦金实业有限公司 Health care white spirit and brewing method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102337196A (en) * 2011-09-08 2012-02-01 宁波红龙生物科技有限公司 Haematococcus alcoholic drink and preparation method thereof
CN102337196B (en) * 2011-09-08 2013-06-26 宁波红龙生物科技有限公司 Haematococcus alcoholic drink and preparation method thereof
CN102512501A (en) * 2012-01-01 2012-06-27 山东大学威海分校 Preparation method of compound Chinese magnoliavine fruit preparation and antioxidant activity thereof
CN102512501B (en) * 2012-01-01 2013-10-23 山东大学威海分校 Preparation method of compound Chinese magnoliavine fruit preparation and antioxidant activity thereof
CN102851177A (en) * 2012-09-24 2013-01-02 朱劲荣 Glutinous rice/chlorella mixed and brewed selenium-rich yellow wine
CN102876544A (en) * 2012-10-26 2013-01-16 上海麦金实业有限公司 Health care white spirit and brewing method thereof

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