CN1385168A - External used functional medicine whose Chinese medicine prescription intensified by snake macro-micro element - Google Patents

Abstract

The present invention discloses a functional medicine preparation whose prescription is intensified by snake macro-micro elements necessary for human body for external application. It is characterized by that it utilizes percutaneous osmosis and adsorption to supplement trace elements to attain the goal of curing dermatosis. Its therapeutic effect is good and its cure rate is high.

Description

The Serpentis macro micro element is strengthened the external used functional medicine of Chinese medicine preparation

Technical field:

The present invention relates to the external used medicine in the medicine, is a kind of external type Chinese medicinal formulae that contains the tissue substance of Serpentis, specifically, is the external used functional medicine of strengthening Chinese medicine preparation with tissue substance and the macro micro element of Serpentis.It is pure natural nature animals and plants trace element topical agent.

Background technology:

Macro micro element plays an important role in the human life activity, and lack or too much, all can cause the corresponding disease of human body, in addition dead.Dermatitis, acne, psoriasis, eczema, vitiligo are just relevant with elements such as zinc deficiency, cobalt, manganese, copper.From domestic and international great mass of data and clinical practice thereof, skin contains zinc and accounts for 20% of whole body zinc content, and has many dermatosiss to lack relevant with elements such as human body zinc, copper, cobalts.The shortage of common human body trace element, 80% all absorbs by diet and drinking-water.The present invention is by dermal osmosis, absorbs trace element supplement, reaches the dermopathic purpose of treatment.Macro micro element content is extremely abundant in the Serpentis class medical material, macroelement calcium, phosphorus, potassium, sodium, content of magnesium are the highest, and micronutrient levelss such as zinc, ferrum, manganese, copper are also high, and zinc, manganese are the important activator of human body plurality of enzymes, the promotion wound healing is arranged, the enhancing human body immunity function.Facts have proved, not only contain abundant macro micro element in the Serpentis body, but also contain very high protein, fatty acid, aminoacid, cholesterol and black body and multivitamin, and these materials can improve zinc bioavailability and absorbance in human body, and the trace element of Chinese medicine complex state in vivo, has selection, enrichment and to the special affinity interaction of organ.And the dermopathic medicine of existing treatment is selected chemicals or hormone usually for use, and the curative effect of these existing medicines is unsatisfactory, causes many dermatosiss to become the persistent ailment that is difficult to cure.

Summary of the invention:

The purpose of this invention is to provide a kind of Serpentis macro micro element and strengthen the external used functional medicine of Chinese medicine preparation, comprise the dermopathic Chinese medicine exterior-applied prescription of treatment, it is characterized in that: other is added with each tissue substance of Serpentis, and reinforcement has the macro micro element composition more than three kinds or three kinds that needs in the human body.

Each tissue substance of Serpentis described in the present invention comprises at least a in Carnis Serpentis, Fel Serpentis, Adeps Serpentis, Periostracum Serpentis, Periostracum Serpentis, snake venom, Penis et testis Serpentis, Serpentis internal organs, snake egg, protruding tongue, snakehead, ophiruid, snake blood, snake bone etc. and the extract thereof.

Macro micro element described in the present invention is following column element:

Ca (calcium); P (phosphorus); Mg (magnesium); Fe (ferrum); Al (aluminum); Zn (zinc); Sr (strontium); Ti (titanium); Mn (manganese); V (vanadium); Cu (copper); Ba (barium); Cr (chromium); In (indium); Rb (rubidium); Cd (cadmium); Mo (molybdenum); Ni (nickel); Cl (chlorine); Co (cobalt); K (potassium); Na (sodium); S (sulfur); Si (silicon); B (boron); Bi (bismuth); Ge (germanium); Li (lithium); Sb (antimony); Ce (cerium); Ga (gallium) etc.

Each tissue substance being added with Serpentis described in the present invention is the content range of macro micro element in the functional medicine of leading:

Ca (calcium) 0.001～150000 μ g/g;

P (phosphorus) 0.001～80000 μ g/g;

Mg (magnesium) 0.00145～30000 μ g/g;

Fe (ferrum) 0.0001036～1200.00 μ g/g;

Al (aluminum) 0.001～1100.00 μ g/g;

Zn (zinc) 0.0003345～150.00 μ g/g;

Sr (strontium) 0.001～110.00 μ g/g;

Ti (titanium) 0.0000001～20.00 μ g/g;

Mn (manganese) 0.000001～15.00 μ g/g;

V (vanadium) 0.000000001～2.00 μ g/g;

Cu (copper) 0.0000137～57.00 μ g/g;

Ba (barium) 0.000001～110.00 μ g/g;

Cr (chromium) 0.0000001～5.00 μ g/g;

In (indium) 0.001～2.00 μ g/g;

Rb (rubidium) 0.01～5.000 μ g/g;

Cd (cadmium) 0.001～0.40 μ g/g,

Mo (molybdenum) 0.0001～3.50 μ g/g;

Co (cobalt) 0.001～0.70 μ g/g;

Ni (nickel) 0.0000001～0.90 μ g/g;

Cl (chlorine) 0.01～2.00 μ g/g;

K (potassium) 0.0001～1.70 μ g/g;

Na (sodium) 0.00001～0.30 μ g/g;

S (sulfur) 0.001～32.00 μ g/g;

Si (silicon) 0.01～27.00 μ g/g;

As (arsenic) 0.1～4.30 μ g/g;

Se (selenium) 0.01～2.50 μ g/g;

Pb (lead) 0.05～2.00 μ g/g;

Li (lithium) 0.05～5.00 μ g/g;

Contain in the following traditional Chinese medicines composition one or more in the Chinese medicinal formulae described in the present invention:

Radix Et Rhizoma Rhei, Cortex Phellodendri, Rhizoma Coptidis, the Radix Astragali, Galla Chinensis, Natrii Sulfas, Rhizoma Paridis, Realgar, succinum, Alumen, Radix Angelicae Sinensis, hair, Pheretima, Scolopendra, Ramulus Cinnamomi, Flos Genkwa, Flos Carthami, Flos Lonicerae, Fructus Zanthoxyli, dried hot pepper, Olibanum, Rhizoma Zingiberis, the Radix Angelicae Dahuricae, Radix Polygoni Multiflori, Rhizoma Polygonati Odorati, the Rhizoma Anemarrhenae, Rabdosia rubescens, Lithargyrum, Radix Sophorae Flavescentis, Fructus Cnidii, Herba Artemisiae Anomalae, the Radix Stemonae, Borneolum Syntheticum, Camphora, Cortex Dictamni, Mentholum etc.

The dermopathic Chinese medicine exterior-applied prescription of treatment described in the present invention comprises the Chinese medicinal formulae of strengthening with the Fel Serpentis trace element with eliminating fire and detoxication, clearing away heat-damp and promoting diuresis, detumescence wound skin ulcer; Or have wetly through cold expelling, and promoting blood circulation to remove obstruction in the collateral, skin care, improve blood fortune, promote the Chinese medicinal formulae of tissue repair; Maybe can relieve dizziness, high fever, infantile convulsions, epilepsy, etc., go wind, heat clearing away, antiinflammatory, antipruritic, cool heart-fire, move back heat in blood, remove fidgety, eliminating fire and detoxication, the replenishing kidney-YIN Chinese medicinal formulae; Maybe can treat the uneven synthetic zinc element of hormone that participates in of the interior estrogen and androgen of comedo patient body and reduce additional zinc element adjusting hormonal balance, use simultaneously and all can suppress lipase activity minimizing bacterial reproduction, the Chinese medicinal formulae of anti-inflammation propionibacterium acnes and staphylococcus.

The dermopathic Chinese medicine exterior-applied prescription of treatment described in the present invention comprises the Chinese medicinal formulae of the treatment fungal infection of strengthening with the Agkistrodon halys trace element; Or be used for the Chinese medicinal formulae of dermatitis aestivale miliaria; Or being used for the treatment of leukodermic Chinese medicinal formulae, its prescription is: Flos Carthami, Ramulus Cinnamomi, each 10-20g of Cortex Moutan, Radix Et Rhizoma Rhei 20-40g, Fructus Psoraleae 40-60g, Semen Cuscutae, Fructus Gardeniae, Radix Salviae Miltiorrhizae, each 15-25g of Radix Polygoni Multiflori, Agkistrodon halys 50-100g.。

The dermopathic Chinese medicine exterior-applied prescription of treatment described in the present invention comprises that strengthening Chinese medicine preparation with Agkistrodon halys trace element or Fel Serpentis trace element is used for the violent pruritus that causes because of acaricide, agonizing, the Chinese medicine exterior-applied prescription that unique killing parasites for relieving itching is arranged, its prescription is: sulfur 40-60g, Resina Draconis, Calamina, Semen Hydnocarpi, Pericarpium Zanthoxyli, Mirabilitum, Semen Arecae, each 5-20g of the Fructus Evodiae, salicylic acid 2g or dried Alumen 20g, each 30g; Or hundred the step 80-120g, each 70-90g of Radix Sophorae Flavescentis Cortex Dictamni, Pericarpium Zanthoxyli 20-40g, Alumen 15-25g, Camphora 5-15g, Borneolum Syntheticum 3-9g.

The dermopathic Chinese medicine exterior-applied prescription of treatment described in the present invention comprises with the Adeps Serpentis trace element strengthens the acute and chronic scytitis that the Chinese medicine preparation treatment is caused by internal and external factor, the violent pruritus of showing effect repeatedly, the Chinese medicine exterior-applied prescription of the eczema that is difficult to treat, its prescription is: Borax 15-25g, sulfur 90-110g, Camphora, each 5-15g of Cinnabaris, dried Alumen, each 3-8g of Realgar, Rhizoma Coptidis, each 20-40g of Pulvis Talci, Borneolum Syntheticum 10-20g; Or Radix Angelicae Dahuricae 30-50g, Camphora 20-40g, the Fructus Kochiae, Cortex Dictamni, Fructus Cnidii, each 20-30g of Herba Menthae.

The dermopathic Chinese medicine exterior-applied prescription of treatment described in the present invention comprises with Adeps Serpentis or the Chinese medicine preparation strengthened with trace element in the immersion of Periostracum Serpentis vinegar, be treatment outbreak repeatedly clinically, the psoriatic Chinese medicine exterior-applied prescription of typical case's skin lesion, its prescription is: Radix Sangusorbae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Cnidii, each 5-15g of Fructus Gardeniae, Flos Sophorae, the Fructus Kochiae, the Radix Rehmanniae, each 20-40g of Radix Paeoniae Rubra, Galla Chinensis 10-20g, Radix Sophorae Flavescentis 15-25g, Periostracum Serpentis 30-50g; Or Radix Arnebiae (Radix Lithospermi), Olibanum, each 10-20g of Myrrha, Semen Armeniacae Amarum, 15-25g, Alumen 5-15g; Or Radix Rumicis, Fructus Cnidii, each 25-35g of Cortex Hibisci, Agkistrodon halys 50-100g.

Beneficial effect of the present invention is: the present invention is high-new biological technical field, element medicine, be at atom, study with the attention macro micro element on the molecular biotechnology basis, observe, experiment, practice, mainly solve to replenish the method for balance trace element, remove the third generation medical science of the highest level of people's dermatosis sufferings, i.e. Chinese Chinese medicine in development practice in several thousand, be traditional drugs---first generation medical science, with western medicine and medical practitioners be on the basis of second filial generation medical science, take place, find, the third generation medical science that grows up, be the part in the trace element medical science, the application of trace element medical science on dermatological is a brand-new new Medical Technology.And Serpentis is always to treat dermopathic key medicine, makes the trace element topical agent by the reinforcement screening of animal and plant medicine trace element, and dermatosis is truly had beyond thought definite curative effect.Strengthen the Chinese medicine preparation curative effect with trace element in natural animal, Serpentis and each tissue thereof, reach the various skin disease that causes because of the trace element imbalance to regulate element balance.Strengthen Chinese medicine preparation with the Serpentis macro micro element, make that inherent organic active ingredient is strengthened in the Chinese medicine, and can quicken to promote the absorption of macro micro elements such as zinc, copper, manganese, effectively bring into play the dual function of herbal medicine efficacy and trace element, so curative effect is peculiar.

The present invention is described in further detail below in conjunction with embodiment:

The specific embodiment:

The preparation method of the functional topical agent of macro micro element among the present invention:

1, animal and plant medicine is preferred.

1.1 Serpentis class medical material is preferred:

Select various different types of Serpentiss for use, porphyrize becomes powder respectively, cross 40 mesh sieves, in 80 ℃ of baking boxes to constant temperature, measure various Serpentis class medical material micronutrient levelss with ∏ type inductive argon ion emission spectrometer, filter out Zn (zinc), Mg (magnesium), Al (aluminum), the Mn maximum Serpentis kinds of micronutrient levels such as (manganese), determine that at last with Agkistrodon halys be main medication batching.

1.2 plant amedica and prescription is preferred.

Over thousands of years, the treatment of the Chinese medicine of China, medication experience is told us, and safety of traditional Chinese medicine obviously is better than chemical medicine, but drug effect is starkly lower than similar chemical medicine again, this and traditional Chinese medicine processing have much relations, improve concocting method and be primarily successful point of the present invention, prescription preferred, we are from numerous secret recipes is formed, monomer Chinese medicine is carried out trace elements determination, and preferably the element to dermatosis patient lacks the high definite new medication prescription of monomer Chinese medicine constituent content in this prescription.

2, Chinese medicine extraction:

The prescription medication that we will determine, single respectively weighing are good, extract respectively or with 95% alcohol-pickled recovery ethanol concentration extraction with supercritical CO 2 extraction device.

2.1 extracting process:

2.1.1 after will screening good Serpentis alives and placing a week, squeeze, emptying Serpentis body Excreta puts into 95% alcoholic solution and take out Serpentis after 15 days, recovered alcohol is concentrated standby again.

Kill 2.1.2 will screen good Serpentis alive, internal organs are removed in peeling, and it is standby to be cut into cun segment length's meat section.

2.1.3 with Serpentis intestinal, liver, spleen, pancreas, lung, whip, ovum, skin, bone, slough off, head, ophiruid, protruding tongue etc. are cleaned respectively, dry that to grind into smalls standby.

To make the crystallization of dry powder powder standby 2.1.4 snake venom, snake blood, Fel Serpentis (wearing out extracting juice) carry out the freezing vacuum.

2.1.5 Chinese medicine is cleaned, cutting, to dry, be crushed to constant weight standby.

Above-mentioned all animal and plant medicine weighings are well directly packed into can extract automatically after adding the agent of refreshing band in the abstraction pool.

3, above-mentioned each tissue and Chinese medicine extract allow to occupy the percentage ratio of weight in the trace element medicament:

3.1 the extract of Carnis Serpentis, intestinal, liver, lung, spleen, pancreas, whip, snakehead, protruding tongue, snake bone, Serpentis ovum, Periostracum Serpentis, ophiruid is respectively: 0.005～50%

3.2 Adeps Serpentis 0.005～50%

3.3 snake venom, gallbladder, blood, freezing dry powder 0.0001～30%

3.4 various units Chinese medicine extract 0.05～50%.

The said Serpentis of the present invention is the Serpentis of general reference, comprises Serpentis classes all on the earth, if any poisonous snake, and nonpoisonous snake, land Serpentis, desert Serpentis, ocean Serpentis, the macro micro element effective ingredient in the various Serpentis bodies such as coastal waters and deep-sea Serpentis.

Emphasis of the present invention is to make with macro micro element reinforcement Chinese medicine preparation in each tissue of Serpentis to be used for common throughout the year multiple dermatosis such as herpes zoster, bursting by freezing, neurodermatitis, acne of youth, brothers' thigh tinea capitis, scabies, eczema, psoriasis, miliaria, dermatitis aestivale, treatments such as vitiligo have very peculiar effect.

Another emphasis point of the present invention is to use combination of Chinese and Western medicine method, adopts molecular biology, trace element medical science, by dermal osmosis, absorb, both replenished shortage because of trace element in the skin sick body, can strengthen Chinese medicine traditional Chinese medical science heat-clearing and toxic substances removing again, fire is let out in antiinflammatory, spleen invigorating dehumidifying, blood circulation promoting and blood stasis dispelling, wind, dissipating cold relaxes, the skin moistening that nourishes blood, Anti-Puritic and insecticidal, collateral dredging multiple efficacies such as relieve dizziness, high fever, infantile convulsions, epilepsy, etc.

The present invention is used for the treatment of neural dermatitis 30 examples, week at least, promptly healed in one month at most, cure rate reaches 78%, is used for acne, 107 examples, 54 examples of fully recovering account for 50.5% (erythra and scleroma, all disappearing, observe a not recurrence in month) remarkable 35 examples account for 32.7% (the basic disappearance of erythra and scleroma leave erythema, idol has single pimple to occur) effective 18 examples, account for 16.8% (erythema still has big portion not disappear for erythra, the disappearance of scleroma part), total effective rate is 100%, treat chilblain 230 examples with the present invention, cured in general three-five days, the treatment tinea corporis and cruris, tinea manus and pedis 156 examples, the general medication of tinea corporis and cruris is cured for two～three times, tinea pedis was cured in five-seven days, and the tinea manuum is cured several repeatedly courses of treatment, i.e. seven days per courses of treatment, tinea corporis and cruris is cured 32 examples and is accounted for 20.5%, tinea pedis interior recovery from illness of one week 75 examples account for 9 examples that healed in 48.9%, two week and account for 27 examples 17.3% that heal in three thoughtful five weeks of 8% tinea manuum, and total cure rate reaches 86.7%.

Be added with the content range that Carnis Serpentis is a macro micro element in the main functional medicine described in the present invention:

Ca (calcium) 50000～150000 μ g/g; P (phosphorus) 20000～80000 μ g/g;

Mg (magnesium) 10000～30000 μ g/g; Fe (ferrum) 50.00～1200.00 μ g/g;

Al (aluminum) 20.00～1100.00 μ g/g; Zn (zinc) 40.00～150.00 μ g/g;

Sr (strontium) 3.00～110.00 μ g/g; Ti (titanium) 0.01～20.00 μ g/g;

Mn (manganese) 1.00～15.00 μ g/g; V (vanadium) 0.30～2.00 μ g/g;

Cu (copper) 1.00～40.00 μ g/g; Ba (barium) 1.300～110.00 μ g/g;

Cr (chromium) 0.00～5.00 μ g/g; In (indium) 0.00～2.00 μ g/g;

Rb (rubidium) 0.10～4.000 μ g/g; Cd (cadmium) 0.00～0.40 μ g/g,

The content range of macro micro element in based on the functional medicine of Adeps Serpentis described in the present invention:

Zn (zinc) 25.00～80.00 μ g/g; Mn (manganese) 3.00～10.00 μ g/g;

Fe (ferrum) 70.00～180.00 μ g/g Ca (calcium) 1200～9000 μ g/g;

Mg (magnesium) 1000～3500 μ g/g; Cu (copper) 10.00～57.00 μ g/g;

Mo (molybdenum) 2.00～2.50 μ g/g; Co (cobalt) 0.20～0.70 μ g/g;

P (phosphorus) 1200～1500 μ g/g,

The content range of macro micro element in based on the functional medicine of Fel Serpentis described in the present invention:

Zn (zinc) 2.00～4.00 μ g/g; Cu (copper) 0.005～0.05 μ g/g;

Fe (ferrum) 2.00～5.00 μ g/g; Ba (barium) 0.05～1.00 μ g/g;

Mn (manganese) 0.03～0.15 μ g/g; Al (aluminum) 2.00～3.00 μ g/g;

Mo (molybdenum) 0.0015～0.005 μ g/g; Ni (nickel) 0.005～0.05 μ g/g;

Cl (chlorine) 0.05～0.20 μ g/g; Cd (cadmium) 0.003～0.01 μ g/g;

Mg (magnesium) 1.50～2.50 μ g/g; Sr (strontium) 0.005～0.09 μ g/g,

The content range of macro micro element in based on the functional medicine of Periostracum Serpentis described in the present invention:

Al (aluminum) 0.30～15.00 μ g/g; Ca (calcium) 0.200～0.45 μ g/g;

Cl (chlorine) 0.50～2.00 μ g/g; Cr (chromium) 0.10～0.14 μ g/g;

Cu (copper) 0.07～0.098 μ g/g; Fe (ferrum) 0.50～3.20 μ g/g;

K (potassium) 0.41～1.70 μ g/g; Mg (magnesium) 0.12～0.30 μ g/g;

Mn (manganese) 0.07～0.13 μ g/g; Na (sodium) 0.15～0.22 μ g/g;

Ni (nickel) 0.06～0.88 μ g/g; P (phosphorus) 2.00～3.00 μ g/g;

S (sulfur) 22.00～32.00 μ g/g; Si (silicon) 4.50～27.00 μ g/g;

Ti (titanium) 0.11～0.135 μ g/g; Zn (zinc) 0.14～0.24 μ g/g,

The content range of macro micro element in based on the functional medicine of Agkistrodon halys described in the present invention:

Ba (barium) 0.00002530～0.00002730 μ g/g;

Ca (calcium) 0.589～0.789 μ g/g;

Cr (chromium) 0.00000047～0.00000247 μ g/g;

Cu (copper) 0.0000137～0.0000157 μ g/g;

Fe (ferrum) 0.0001036～0.0003036 μ g/g;

K (potassium) 0.0068～0.0088 μ g/g;

Mg (magnesium) 0.00145～0.00165 μ g/g;

Mn (manganese) 0.00000274～0.00000474 μ g/g;

Na (sodium) 0.00506～0.00706 μ g/g;

Ni (nickel) 0.00000311～0.00000511 μ g/g;

P (phosphorus) 2.666～4.66 μ g/g;

Sr (strontium) 0.1612～0.1812 μ g/g;

Ti (titanium) 0.00000466～0.00000666 μ g/g;

V (vanadium) 0.000000467～0.000000667 μ g/g;

Zn (zinc) 0.0003345～0.0004345 μ g/g,

The content range of macro micro element in based on the functional medicine of six kinds of Agkistrodon halyss of China described in the present invention:

Six kinds of Agkistrodon halyss comprise: Chinese Naja, Changbai mountain, Jilin white-browed Serpentis, Anqing, Jiangxi Agkistrodon halys, Zhejiang, Jiangsu Agkistrodon halys, each province, south China Agkistrodon acutus, Dalian agkistrodon shedaoensis,

Zn (zinc) 120～500 μ g/g; Mg (magnesium) 70～350 μ g/g;

Fe (ferrum) 8～50 μ g/g; Cu (copper) 0.80～5.50 μ g/g;

Mo (molybdenum) 1.00～3.50 μ g/g; As (arsenic) 1.02～4.30 μ g/g;

Cr (chromium) 0.50～3.00 μ g/g; Se (selenium) 0.50～2.50 μ g/g;

Ni (nickel) 0.25～0.80 μ g/g; Pb (lead) 0.07～2.00 μ g/g;

V (vanadium) 0.05～0.85 μ g/g; Co (cobalt) 0.20～0.50 μ g/g

Mn (manganese) 0.25～0.50 μ g/g; Li (lithium) 0.07～5.00 μ g/g;

Cd (cadmium) 0.03～0.06 μ g/g,

The following examples are the several typical cases in the macro micro element prescription of the present invention, according to description of the invention, can prepare following a plurality of different formulations, the trace element external prescription of different efficacies, and these belong within protection scope of the present invention.

Embodiment 1:

Radix Et Rhizoma Rhei, each 30g of Cortex Phellodendri

Galla Chinensis, each 15g of Natrii Sulfas

Embodiment 2:

Rhizoma Coptidis 30g, Rhizoma Paridis 50g, Realgar 60g, succinum, each 90g of Alumen, Scolopendra 20g

More than two sides, be have eliminating fire and detoxication, the prescription of clearing away heat-damp and promoting diuresis, detumescence wound skin ulcer.Chinese medicine pulverized 120 mesh sieves respectively, each side puts into abstraction pool each side after extracting respectively and adds respectively and contain Fel Serpentis trace element emulsifying base and be made into its matter ointment of emulsifying of 20-30% respectively or single grind to the powder then or toast dried grinding to the powder with Pheretima and make the topical agent that contains the Fel Serpentis trace element and be used for the treatment of herpes zoster 130 examples with natural thick dark hair point, medication secondary at least, six times at most, all obtain recovery from illness average five times.

Contain Fel Serpentis medicine for external use and preparation method: at first make the Fel Serpentis that emulsifying base adds 0.5-5%, referring to Shanghai City hospital preparation handbook third edition 1989.69-72 and patent of invention patent No. ZL89109574.8, or pulverize with natural thick dark hair 150 gram dried earthworm powder 80g and to make Fel Serpentis trace element topical agent.

Embodiment 3:

Flos Genkwa, Radix Angelicae Sinensis, each 50g of Ramulus Cinnamomi, Flos Carthami, each 25g of Flos Lonicerae

Medicine-feeding is pulverized to be extracted into and is soaked recovered alcohol after 15 days in 95% ethanol, 1000 ml solns, and concentrated extracting solution is made the Fel Serpentis trace element topical agent that contains crude drug 15-20%.

Embodiment 4:

Radix Angelicae Sinensis, Herba Asari, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, each 60g of Pericarpium Zanthoxyli,

Flos Genkwa 210g, Flos Carthami 100g, Ramulus Cinnamomi 100g,

Lignum Sappan 100g, 6 in Fructus Capsici, Camphora 30g,

Embodiment 5:

Radix Angelicae Sinensis, each 60g of Cortex Cinnamomi, Flos Carthami, Pericarpium Zanthoxyli, each 30g of Rhizoma Zingiberis, Camphora, each 15g of Herba Asari

Embodiment 6:

Pseudobulbus Bletillae (Rhizoma Bletillae) powder, Radix Angelicae Dahuricae powder, each 60g of Semen Armeniacae Amarum fine powder, Radix Et Rhizoma Rhei 100g, Borneolum Syntheticum 60g

Above-mentioned 3～6 examples are to have and wet through cold expelling, promoting blood circulation to remove obstruction in the collateral, skin care, improve blood fortune, promote the Chinese medicinal formulae of tissue repair, above each side reclaims alcoholic solution after soaking first quarter moon with the 75%-95% edible ethanol, extract active ingredient, make the topical agent of the Serpentis macro micro element in the emulsifiable paste matrix that contains crude drug composition 20-30% that contains Adeps Serpentis trace element oil-in-water type after contracting deeply.

Above each side treating chilblain 90 examples, 120 examples of chapping, curative day chilblain 15 days was chapped effective percentage 100% 5 days.

Embodiment 7:

Pheretima, Zaocys, Radix Angelicae Sinensis, each 30g of Radix Sophorae Flavescentis, Fructus Atriplicis Sibiricae, the Radix Rehmanniae, Radix Polygoni Multiflori Preparata, Rabdosia rubescens, each 30g of Fructus Crataegi (parched to brown), Radix Scutellariae, Rhizoma Chuanxiong, Rhizoma Atractylodis, each 10g of Flos Carthami.

Embodiment 8:

Rabdosia rubescens, green copper, Lithargyrum, wood rosin, each 30g of hydrocerussitum, borneol, each 5g of stupid phenol.

Embodiment 9:

Cortex Phellodendri, Radix Scutellariae, Radix Angelicae Sinensis, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Cacumen Platycladi, each 30g of Herba Violae, Rhizoma Polygonati Odorati, each 15g of the Rhizoma Anemarrhenae.

Embodiment 10:

Sulfur, arsenicum sablimatum are fried each 50g, Scorpio 20g, Fructus Arctii 35g, Periostracum Cicadae, each 25g of Radix Notoginseng, Moschus 0.6g.

Embodiment 11:

Rhizoma Coptidis 25g, cnidium monnieri, each 50g of Radix Sophorae Flavescentis, Agkistrodon halys 100g, Radix Et Rhizoma Rhei, Herba Artemisiae Anomalae, the Radix Stemonae, Pericarpium Zanthoxyli, each 15g of Borneolum Syntheticum.

Above-mentioned 7～11 examples be for relieving dizziness, high fever, infantile convulsions, epilepsy, etc., go wind, heat clearing away, antiinflammatory, antipruritic, cool heart-fire, move back heat in blood, remove fidgety, eliminating fire and detoxication, the Chinese medicinal formulae of replenishing kidney-YIN.Above each side puts into abstraction pool respectively and is made into the trace element medicine for external use example of the emulsifiable paste that contains crude drug 15-25% with the emulsifying base of Fel Serpentis trace element, is used for the treatment of neurodermatitis 32 examples, 28 examples of fully recovering, effective 4 examples, effective percentage 100%, recovery from illness natural law, the shortest week, the longest 30 days.

Model case:

Lee so-and-so, the man, 52 years old, neural dermatitis was suffered from 5 years by neck, fossa cubitalis portion, repeatedly treatment is not healed, and with the back recovery from illness of three week of we treatment, sees recurrence of year.

Embodiment 12:

Fructus Cnidii, the Fructus Kochiae, each 500g of Radix Sophorae Flavescentis,

Cortex Cinnamomi, Cortex Dictamni, Semen Hydnocarpi meat, each 300g of Cortex Hibisci,

Sulfur, each 200g of Alumen, Agkistrodon halys 500g

Medicine-feeding is pulverized extraction and is immersed in 5000 milliliters of 95% alcoholic solutions, stirs every day three times, takes off clear liquid after 15 days and adds fully dissolving back usefulness of Camphora 200 grams again, and last two sides are used for the treatment of brothers' tinea corporis and cruris specially good effect.

Embodiment 13:

Sulfur 50g, white scorpion, Calamina, each 10g of Semen Hydnocarpi,

Mirabilitum, each 10g of Pericarpium Zanthoxyli, salicylic acid 2g (or using dried Alumen 20g)

Fructus Evodiae 15g, Semen Arecae 15g, the Yuan 30g that clears the fields of weeds

The fine ground extraction of above-mentioned medicine back directly adds in emulsifying base 500 grams that contain the Adeps Serpentis trace element standby, is used for scabies 63 examples, and more cure rate reached 100% in three-five days in general medication.

Embodiment 14:

Hundred step 100g, Radix Sophorae Flavescentis, each 80g of Cortex Dictamni,

Pericarpium Zanthoxyli 30g, Alumen 20g, Camphora 10g,

Borneolum Syntheticum 6g, Agkistrodon halys 150g.

Said medicine pulverize be taken into soak 15 days in 1500 milliliters of 95% ethanol after, have a bath by the medicament of 10% preparation with Natrii Sulfas 50 grams, Periostracum Serpentis water every day, logotype one all scabies promptly heal.

Embodiment 15:

Radix Angelicae Dahuricae 40g, the Fructus Kochiae, Cortex Dictamni, Fructus Cnidii, each 25g of Herba Menthae, Camphora 36g, Agkistrodon halys 200g.

Said medicine is except that Camphora pulverizes separately, and surplus all pulverizing is extracted in 95% ethanol, 2000 ml solns, and camphorating at last stirs jointly, be suitable for urticaria, children's's skin pruritus, dermatitis aestivale, acute and chronic eczema etc.

Embodiment 16:

Borax 20g, sulfur 100g, dried Alumen 6g, Camphora 10g, Borneolum Syntheticum 15g, Cinnabaris 10g, Rhizoma Coptidis 30g, Pulvis Talci 30g, Realgar 5g.

The fine ground end of said medicine, extraction; Can be if any the sepage that serious eczema causes directly with directly smearing the affected part in the extract infiltration Pulvis Talci, no transudate can add with extract contain treatment eczema 173 examples in the Adeps Serpentis trace element emulsifiable paste, minimum 7 days, all recoveries from illness in maximum 25 days.

Embodiment 17:

Radix Sangusorbae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Cnidii, each 10g of Fructus Gardeniae,

Flos Sophorae, the Fructus Kochiae, the Radix Rehmanniae, each 30g of Radix Paeoniae Rubra,

Galla Chinensis, each 20g of Radix Sophorae Flavescentis, Periostracum Serpentis 100g.

Said medicine is pulverized extraction back and is dropped in 1000 milliliters of the bath lotions or Radix Arnebiae (Radix Lithospermi) 30g, Olibanum, each 30g of Myrrha again in the above-mentioned prescription, Semen Armeniacae Amarum 20g, Alumen 10g pulverize the adding of extraction back jointly and contain among the emulsifying base 2000g of Adeps Serpentis trace element, make and contain Adeps Serpentis trace element topical agent, with these side's treatment psoriasis 100 examples, 26 examples of fully recovering.

Embodiment 18:

Radix Rumicis, Fructus Cnidii, each 30g of Cortex Pseudolaricis, Agkistrodon halys 150g.

Said medicine grind the extraction back add soak in 1000 milliliters of 95% ethanol 15 days standby, other gets salicylic acid 60 gram, benzoic acid 120 grams and immerses in 500 milliliters of 95% ethanol fully stirring and dissolving, the ethanol that will be soaked with Chinese medicine then leaches two liquid, and fully stirring and evenly mixing is standby.

Treat psoriasis 85 examples altogether, cure rate reaches 85%, general all recoveries from illness or be clearly better in 50 days.

Trace element magnesium, the content height of ferrum, zinc, manganese, psoriatic's 30 examples are sent out in the inspection, and zinc, lead, ferrum are obviously low, and chromium nickel content is significantly high, reaches psoriasis by element balance.

Embodiment 19:

Radix et Rhizoma Rhei (processed) 100g, Cortex Phellodendri 20g, Borneolum Syntheticum 3g, Mentholum 6g, Realgar 10g, Rhizoma Coptidis 10g, Agkistrodon halys 50g,

Said medicine grinds extraction and immerses 95% alcoholic solution 500ml, and is standby after 15 days, and with we's treatment miliaria 180 examples, cure rate reaches 99.2%.

Embodiment 20:

Herba Senecionis Scandentis 500g, Radix Et Rhizoma Rhei 300g, Agkistrodon halys 600g.

Above-mentioned medicine grinds extraction and immersed in 4000 milliliters of 95% alcoholic solutions 15 days, makes Agkistrodon halys trace element topical agent, treatment dermatitis aestivale 50 examples, and 38 examples of fully recovering account for 76%, have significant curative effect 12 examples to account for 22%, effective 1 example, total effective rate 100%.

Embodiment 21:

Cortex Phellodendri, Semen Arecae, sulfur, Realgar, each 10g of dried Alumen,

Rhizoma Atractylodis Macrocephalae (parched), each 9g of Radix Angelicae Dahuricae powder, Vermilion 30g,

Said medicine grinds extraction and enters and contain the Serpentis class and organize in the trace element emulsifying agent substrate, makes trace element topical agent treatment solar dermatitis.

Example example 22:

Flos Carthami, Ramulus Cinnamomi, each 15g of Cortex Moutan, Radix Et Rhizoma Rhei 30g, Fructus Psoraleae 50g, Semen Cuscutae, Fructus Gardeniae, each 20g of Radix Salviae Miltiorrhizae, Radix Polygoni Multiflori 20g, Agkistrodon halys 50g

Said medicine grinds, and recovered alcohol after 15 days is immersed in 500 milliliters of 95% ethanol in extraction, extracts active ingredient, makes Agkistrodon halys trace element topical agent.

Illustrate:

1, in above each prescription, owing to used Serpentis and each tissue of Serpentis to make, for preventing, therefore in prescription, adds 0.5% anti-allergic agent and reach with hypo-allergenic because of foreign preteins stimulates reactions such as causing skin allergy.

2, so-called trace element is strengthened Chinese medicine preparation, that is to say that macro micro element must reach the needed element magnitude of recruitment of this disease in prescription, otherwise can in prescription, add corresponding microelement enhancer and reach the standard consumption, specifically, the not enough available zinc sulfate of element zinc, zinc lactate, zinc gluconate is a hardening agent, also available zinc chloride, zinc acetate is a zinc enhancer, elemental iron can be used ferrous sulfate, ferrous lactate, Ferrous gluconate, ferric citrate, ferrous fumarate, ferric ammonium citrate is as ferrous-fortifier, and elemental selenium can be used sodium selenite, sodium selenate, yeast rich in selenium, it is selenic hardening agent that the selenizing Bian draws glue.Elemental copper can be with curpic carbonate, copper sulfate, do the copper hardening agent.Element manganese can need to replenish enough trace element amounts to reach with the hardening agent etc. that manganese chloride, manganese sulfate are made manganese.

Claims (10)

1, a kind of Serpentis macro micro element is strengthened the external used functional medicine of Chinese medicine preparation, comprise the dermopathic Chinese medicine exterior-applied prescription of treatment, it is characterized in that: other is added with each tissue substance of Serpentis, and reinforcement has the macro micro element composition more than three kinds or three kinds that needs in the human body.

2, Serpentis macro micro element according to claim 1 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: each tissue substance of Serpentis comprises at least a in Carnis Serpentis, Fel Serpentis, Adeps Serpentis, Periostracum Serpentis, Periostracum Serpentis, snake venom, Penis et testis Serpentis, Serpentis internal organs, snake egg, protruding tongue, snakehead, ophiruid, snake blood, snake bone and the extract thereof.

3, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: macro micro element is following column element:

Ca (calcium); P (phosphorus); Mg (magnesium); Fe (ferrum); Al (aluminum); Zn (zinc); Sr (strontium); Ti (titanium); Mn (manganese); V (vanadium); Cu (copper); Ba (barium); Cr (chromium); In (indium); Rb (rubidium); Cd (cadmium); Mo (molybdenum); Ni (nickel); Cl (chlorine); Co (cobalt); K (potassium); Na (sodium); S (sulfur); Si (silicon); B (boron); Bi (bismuth); Ge (germanium); Li (lithium); Sb (antimony); Ce (cerium); Ga (gallium) etc.

4, Serpentis macro micro element according to claim 3 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: at each tissue substance that is added with Serpentis is the content range of macro micro element in the functional medicine of leading:

Ca (calcium) 0.001～150000 μ g/g;

P (phosphorus) 0.001～80000 μ g/g;

Mg (magnesium) 0.00145～30000 μ g/g;

Fe (ferrum) 0.0001036～1200.00 μ g/g;

Al (aluminum) 0.001～1100.00 μ g/g;

Zn (zinc) 0.0003345～150.00 μ g/g;

Sr (strontium) 0.001～110.00 μ g/g;

Ti (titanium) 0.0000001～20.00 μ g/g;

Mn (manganese) 0.000001～15.00 μ g/g;

V (vanadium) 0.000000001～2.00 μ g/g;

Cu (copper) 0.0000137～57.00 μ g/g;

Ba (barium) 0.000001～110.00 μ g/g;

Cr (chromium) 0.0000001～5.00 μ g/g;

In (indium) 0.001～2.00 μ g/g;

Rb (rubidium) 0.01～5.000 μ g/g;

Cd (cadmium) 0.001～0.40 μ g/g,

Mo (molybdenum) 0.0001～3.50 μ g/g;

Co (cobalt) 0.001～0.70 μ g/g;

Ni (nickel) 0.0000001～0.90 μ g/g;

Cl (chlorine) 0.01～2.00 μ g/g;

K (potassium) 0.0001～1.70 μ g/g;

Na (sodium) 0.00001～0.30 μ g/g;

S (sulfur) 0.001～32.00 μ g/g;

Si (silicon) 0.01～27.00 μ g/g;

As (arsenic) 0.1～4.30 μ g/g;

Se (selenium) 0.01～2.50 μ g/g;

Pb (lead) 0.05～2.00 μ g/g;

Li (lithium) 0.05～5.00 μ g/g;

5, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: contain in the following traditional Chinese medicines composition one or more in the described Chinese medicinal formulae:

Radix Et Rhizoma Rhei, Cortex Phellodendri, Rhizoma Coptidis, the Radix Astragali, Galla Chinensis, Natrii Sulfas, Rhizoma Paridis, Realgar, succinum, Alumen, Radix Angelicae Sinensis, hair, Pheretima, Scolopendra, Ramulus Cinnamomi, Flos Genkwa, Flos Carthami, Flos Lonicerae, Fructus Zanthoxyli, dried hot pepper, Olibanum, Rhizoma Zingiberis, the Radix Angelicae Dahuricae, Radix Polygoni Multiflori, Rhizoma Polygonati Odorati, the Rhizoma Anemarrhenae, Rabdosia rubescens, Lithargyrum, Radix Sophorae Flavescentis, Fructus Cnidii, Herba Artemisiae Anomalae, the Radix Stemonae, Borneolum Syntheticum, Camphora, Cortex Dictamni, Mentholum etc.

6, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: treat dermopathic Chinese medicine exterior-applied prescription and comprise the Chinese medicinal formulae of strengthening with the Fel Serpentis trace element with eliminating fire and detoxication, clearing away heat-damp and promoting diuresis, detumescence wound skin ulcer; Or have wetly through cold expelling, and promoting blood circulation to remove obstruction in the collateral, skin care, improve blood fortune, promote the Chinese medicinal formulae of tissue repair; Maybe can relieve dizziness, high fever, infantile convulsions, epilepsy, etc., go wind, heat clearing away, antiinflammatory, antipruritic, cool heart-fire, move back heat in blood, remove fidgety, eliminating fire and detoxication, the replenishing kidney-YIN Chinese medicinal formulae; Maybe can treat the uneven synthetic zinc element of hormone that participates in of the interior estrogen and androgen of comedo patient body and reduce additional zinc element adjusting hormonal balance, use simultaneously and all can suppress lipase activity minimizing bacterial reproduction, the Chinese medicinal formulae of anti-inflammation propionibacterium acnes and staphylococcus.

7, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: treat the Chinese medicinal formulae that dermopathic Chinese medicine exterior-applied prescription comprises the treatment fungal infection of strengthening with the Agkistrodon halys trace element; Or be used for the Chinese medicinal formulae of dermatitis aestivale miliaria; Or being used for the treatment of leukodermic Chinese medicinal formulae, its prescription is: Flos Carthami, Ramulus Cinnamomi, each 10-20g of Cortex Moutan, Radix Et Rhizoma Rhei 20-40g, Fructus Psoraleae 40-60g, Semen Cuscutae, Fructus Gardeniae, Radix Salviae Miltiorrhizae, each 15-25g of Radix Polygoni Multiflori, Agkistrodon halys 50-100g.。

8, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: treat dermopathic Chinese medicine exterior-applied prescription and comprise that strengthening Chinese medicine preparation with Agkistrodon halys trace element or Fel Serpentis trace element is used for the violent pruritus that causes because of acaricide, agonizing, the Chinese medicine exterior-applied prescription that unique killing parasites for relieving itching is arranged, its prescription is: sulfur 40-60g, Resina Draconis, Calamina, Semen Hydnocarpi, Pericarpium Zanthoxyli, Mirabilitum, Semen Arecae, each 5-20g of the Fructus Evodiae, salicylic acid 2g or dried Alumen 20g, each 30g; Or hundred the step 80-120g, each 70-90g of Radix Sophorae Flavescentis Cortex Dictamni, Pericarpium Zanthoxyli 20-40g, Alumen 15-25g, Camphora 5-15g, Borneolum Syntheticum 3-9g.

9, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: treat dermopathic Chinese medicine exterior-applied prescription and comprise that strengthening Chinese medicine preparation with the Adeps Serpentis trace element treats the acute and chronic scytitis that is caused by internal and external factor, the violent pruritus of showing effect repeatedly, the Chinese medicine exterior-applied prescription of the eczema that is difficult to treat, its prescription is: Borax 15-25g, sulfur 90-110g, Camphora, each 5-15g of Cinnabaris, dried Alumen, each 3-8g of Realgar, Rhizoma Coptidis, each 20-40g of Pulvis Talci, Borneolum Syntheticum 10-20g; Or Radix Angelicae Dahuricae 30-50g, Camphora 20-40g, the Fructus Kochiae, Cortex Dictamni, She Dongzi, each 20-30g of Herba Menthae.

10, Serpentis macro micro element according to claim 1 and 2 is strengthened the external used functional medicine of Chinese medicine preparation, it is characterized in that: treat dermopathic Chinese medicine exterior-applied prescription and comprise with Adeps Serpentis or the Chinese medicine preparation strengthened with trace element in the immersion of Periostracum Serpentis vinegar, be treatment outbreak repeatedly clinically, the psoriatic Chinese medicine exterior-applied prescription of typical case's skin lesion, its prescription is: Radix Sangusorbae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Cnidii, each 5-15g of Fructus Gardeniae, Flos Sophorae, the Fructus Kochiae, the Radix Rehmanniae, each 20-40g of Radix Paeoniae Rubra, Galla Chinensis 10-20g, Radix Sophorae Flavescentis 15-25g, Periostracum Serpentis 30-50g; Or Radix Arnebiae (Radix Lithospermi), Olibanum, each 10-20g of Myrrha, Semen Armeniacae Amarum, 15-25g, Alumen 5-15g; Or Radix Rumicis, Fructus Cnidii, each 25-35g of Cortex Hibisci, Agkistrodon halys 50-100g.