CN1379030A - Trace element-vitamine compound and its preparing process and application - Google Patents
Trace element-vitamine compound and its preparing process and application Download PDFInfo
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- CN1379030A CN1379030A CN01106393A CN01106393A CN1379030A CN 1379030 A CN1379030 A CN 1379030A CN 01106393 A CN01106393 A CN 01106393A CN 01106393 A CN01106393 A CN 01106393A CN 1379030 A CN1379030 A CN 1379030A
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Abstract
A trace element-vitamine compound is prepared from vitamines as raw material by use of specific medium, and features high effect on supplementing trace elements and vitamines to human body, easy dissolving in water and absorption by human body, and no by-effect.
Description
The invention relates to a microelement vitamin compound and a preparation method and application thereof. Themicroelement vitamin compound is in liquid state, can be dissolved in water, is easy to be absorbed by human body, directly participates in human body physiological activity, achieves microelement and vitamin double-supplement effect, does not carry ions harmful to human body, and does not produce by-products and side effects.
In addition to fat, protein, carbohydrate, minerals and vitamins, the dynamic balance of these substances must be maintained frequently, and one of the important balances affecting the health and longevity of human body is the element balance. Human beings live in natural environment, through eating, drinking and breathing, elements in human body and environment are exchanged and adjusted continuously, finally reach dynamic balance. Once the elements in the human body are too small to meet the physiological needs of the human body or too large to exceed the limit that the human body can bear, the element balance between the human body and the environment is destroyed, and the human body becomes ill or even dies.
With the change of the age, diet, environment and physiology, the content of various elements in the human body changes. In order to maintain the dynamic balance of various elements in the human body, the content of various elements should be regularly checked so as to be purposefully adjusted and supplemented to reach the standard of healthy people.
Scientific research shows that the elements and vitamins necessary for human body are dozens of kinds. However, in the present situation, it is still unsatisfactory. Firstly, trace element products which can be provided in the current market are only limited to three products of Ca, Fe and Zn, and the requirement of people on health cannot be met by the few varieties. Secondly, inorganic anions such as chloride, sulfate radical and the like in the existing trace elementproducts enter the human body, so that new pollution is caused; some products have poor performance, stimulate the stomach, are difficult to be absorbed and have low transformation rate; some products have unobvious functions and still have no obvious effect after long-time and large-dose taking. Thirdly, according to the record of related data, the metabolism of some trace elements such as calcium in human body needs to be carried out by vitamin D (see pharmaceutical chemistry P342), but only calcium carbonate and vitamin D compound calcium products exist in the market, and no vitamin D calcium product is produced to date; furthermore, it has been found that vitamin C is capable of binding various metal ions, such as Ca, in the digestive tract++、Cd++、Zn++The complex of the iron and the vitamin B can generate unstable ferrous ascorbate with Fe, and the iron ascorbate is beneficial to treating iron deficiency anemia (shown in biochemistry) after being absorbed in intestinal tracts, but no iron deficiency anemia is seen until nowVitamin compound products of these elements are known.
The invention aims to combine two kinds of essential nutrients, namely trace elements and vitamins, necessary for human bodies in a specific medium to generate a series of stable trace element vitamin compounds, so as to supplement the trace elements and the vitamins and realize the aim of double supplement.
Secondly, the method can make up for the small variety of trace element products in the current market, and can meet the requirements of different crowds on body health if new varieties of trace element vitamin compounds with nearly 10 excellent performances, such as magnesium vitamin, zinc vitamin, iron vitamin … …, and the like can be developed.
And thirdly, aiming at the defects of poor product performance and unobvious effect of the current trace element products, the trace element vitamin compound with good performance and remarkable effect needs to be developed.
The implementation content of the invention is as follows: firstly, the raw material requirements are as follows:
1. the vitamins are: vitamin A, B, C, D, E in powder or liquid form
Less than 99.0%.
2. Э iXn, analytically pure, and the requirements of process conditions are as follows:
1. reaction pressure: and (4) normal pressure.
2. Reaction temperature: 18-58 deg.C
3. Material ratio of Э iXn: CαHβNγOδ＝1∶1-1∶10
4. Reaction medium: honey and edible alcohol. Thirdly, material reaction:
1. the reaction formula is as follows:
2. symbol marking:
①、Э：Ca、Cu、Fe、Ge、K、Mg、Mn、Ni、Sr、Zn；
②、X：OH-1、O-2；
③、α：6-31；
④、β：8-52；
⑤、γ：0-4；
⑥、δ：1-6；
⑦、n：1-4；
⑧、m：1-2；
⑨、i：1-3；
⑩ delta, heating mode, and product characteristics:
1. the form is as follows: a transparent or translucent viscous liquid.
2. Color: yellow, orange red, brown and black.
3. Taste sense: sweet taste and no peculiar smell.
4. Solubility: can be dissolved in water, fatty oil, and edible alcohol.
5、PH＜7。
6. Toxic and side effects: the product does not contain inorganic anions harmful to human bodies, does not produce byproducts and has no toxic or side effect on human bodies.
The invention has the advantages that:
1. the invention can skillfully combine two types of nutrient substances, namely trace elements and vitamins, which are indispensable to human bodies in a specific medium to form a brand-new trace element vitamin compound new variety, so that the trace element vitamin compound can supplement trace elements and vitamins for human health, and has the effect of double supplementation.
2. The new product of the nearly 10 microelement vitamin compounds prepared by the invention can meet the requirements of different crowds and different health conditions, and can be selected in a targeted manner.
3. The conditions created by the preparation method of the invention break through the range of books, prepare the microelement vitamin compound with stable performance, and can be further processed into oral liquid, soft capsules or tablets which can be stored for a long time.
4. The microelement vitamin compound prepared by the invention can be dissolved in water, is easy to be absorbed by human body, is the best chemical form directly participating in the physiological activities of human body, does not carry ions harmful to human body, does not produce by-products and side effects, and is a new substance which is not yet appeared at present.
5. The microelement vitamin compound prepared by the invention has better product characteristics and functions than the existing microelement products.
6. When the product is prepared, the invention has the advantages of wide raw material source, short process flow, simple processing equipment, no three-waste pollution, low production cost, less investment, large profit and good economic benefit.
Example (b):
1. preparation of vitamin compound of magnesium:
firstly, ① is determined as raw material for preparation, Э is Mg+1、X＝O-2I-1, n-1 i.e. MgO, ②, vitamin α -6, β -8, γ -0, C6H8O6(ii) a Then weighing a certain amount of C according to the material ratio6H8O6Adding the white crystal powder into 1, 2 and 3-propanetriol in an amount which is 4 to 6 times that of the white crystal powder, stirring the mixture into uniform suspension, heating the suspension while stirring the suspension, and adding white MgO solid powder into the suspension while stirring the suspension, wherein the suspension of the milky white solid of the material is changed into stable brown transparent liquid at the normal pressure reaction temperature of 38 +/-10 ℃. When the material is stored for more than 3 months and no precipitate is separated out, the product is magnesium-ascorbic acid compound, vitamin C magnesium for short, and the chemical formula is Mg (C magnesium)6H7O6)2. And others: ca. The vitamin compounds of Cu, Fe, Ge, K, Mn, Ni, Sr, and Zn were prepared in the same manner as in this example.
2. Application of microelement vitamin compound in animal feedLiquid materials of vitamin compounds such as Ca, Zn, Fe., and the like are mixed in proportion and then stirred into the feed, and the dosage (mg/kg day) of each element is 195 times of the safe dosage of human body. The feeding trial is shown in the following table:
| date | Feeding test | White rabbit weight (g) | Weight gain |
| 2000.5.30 | Start of | 350 | |
| 2000.6.10 | Stop | 650 | The weight of the product is increased by 27.3 g per day |
| 2000.6.23 | Stop | 850 | The weight is increased by 15.4 g per day |
3. The microelement vitamin compound is applied to the aspects of hair blackening, freckle removing, wrinkle reducing and whitening of skin, and the liquid microelement vitamin compound which is mixed according to a proportion is added with a diluent and is used for smearing the hair, scalp and face of the aged 64-66 years old once a day in the morning or evening so that the liquid microelement vitamin compound is absorbed by the cerebral cortex and the facial skin, the white hair can be gradually blackened within 2 months, the black speckles are reduced and faded, and the skin wrinkles are reduced and whitened.
4. The application of the microelement vitamin compound in improving sleep, increasing appetite, eliminating joint ache, muscle spasm, sexual hypofunction and other aspects is that according to the shortage of different crowds to microelements, mixed liquid with different proportions is prepared to be orally taken by 64-65 years old people once per day according to safe amount (mg/kg day), and the microelement vitamin compound can help sleep, promote digestion and increase appetite; and obviously improve or recover a plurality of chronic symptoms such as scapulohumeral periarthritis, joint ache, muscle spasm, sexual hypofunction and the like.
Claims (5)
1. A trace element vitamin compound characterized by:
(1) and product form: a transparent or translucent viscous liquid;
(2) and product color: yellow, orange red, brown and black;
(3) and the taste of the product is as follows: sweet taste and no peculiar smell;
(4) and solubility: can be dissolved in water, fatty oil, and edible alcohol;
(5)、PH＜7；
(6) and toxic and side effects: the product does not contain inorganic anions harmful to humanbodies, and does not produce any by-product and side effect.
2. The method for producing a microelement vitamin compound according to claim 1, wherein:
(1) and raw material requirements are as follows:
①, the vitamins are powder or liquid of vitamin A, B, C, D, E, and the content of the vitamins is not less than 99.0%;
②, the chemical used is Э iXn, its purity is analytical purity;
wherein Э is Ca, Cu, Fe, Ge, K, Mg, Mn, Ni, Sr, Zn;
X：OH-1、O-2；
i：1-3；
n：1-4；
(2) and the process condition requirements are as follows:
①, the reaction pressure is normal pressure;
②, the reaction temperature is 18-58 ℃;
③, material ratio of Э iXn: CαHβNγOδ＝1∶1-1∶10
④, reaction medium including honey and edible alcohol;
(3) and a heating mode: far infrared or microwave;
3. the trace element vitamin compound according to claim 1, wherein: the microelement vitamin compound is applied to animal feed.
4. The trace element vitamin compound according to claim 1, wherein: the microelement vitamin compound can be used in anti-aging health product and cosmetic.
5. The trace element vitamin compound according to claim 1, wherein: the microelement vitamin compound can be used for treating scapulohumeral periarthritis, arthralgia, muscle spasm, and sexual hypofunction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011063939A CN1181076C (en) | 2001-03-29 | 2001-03-29 | Trace element-vitamine compound and its preparing process and application |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011063939A CN1181076C (en) | 2001-03-29 | 2001-03-29 | Trace element-vitamine compound and its preparing process and application |
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| Publication Number | Publication Date |
|---|---|
| CN1379030A true CN1379030A (en) | 2002-11-13 |
| CN1181076C CN1181076C (en) | 2004-12-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB011063939A Expired - Fee Related CN1181076C (en) | 2001-03-29 | 2001-03-29 | Trace element-vitamine compound and its preparing process and application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105285998A (en) * | 2015-11-27 | 2016-02-03 | 杭州海王生物工程有限公司 | Liquid vitamin-mineral composition |
-
2001
- 2001-03-29 CN CNB011063939A patent/CN1181076C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105285998A (en) * | 2015-11-27 | 2016-02-03 | 杭州海王生物工程有限公司 | Liquid vitamin-mineral composition |
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| CN1181076C (en) | 2004-12-22 |
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