CN1367658A

CN1367658A - Method for treating and preventing finger disorders

Info

Publication number: CN1367658A
Application number: CN00811032A
Authority: CN
Inventors: 克里斯廷·刘易斯·穆迪; 曼尼·李·克拉普
Original assignee: Procter and Gamble Ltd
Current assignee: Procter and Gamble Ltd; Procter and Gamble Co
Priority date: 1999-07-30
Filing date: 2000-07-24
Publication date: 2002-09-04
Also published as: WO2001008529A2; WO2001008529A3; EP1199955A2; JP2003505175A; MXPA02001144A; AU5838700A

Abstract

The present invention relates to a method of preventing or treating finger disorders. Specifically, the present invention relates to improved methods of delivery and application of nail and cuticle treatment compositions.

Description

Handle and prevent the method for finger disorders

Invention field

The present invention relates to the method for a kind of prevention or processing finger disorders.Exactly, the present invention relates to provide and apply improving one's methods of fingernail and epidermis processing synthetic.

Background of invention

There are diversified finger or fingernail processing method in the market.The scope of this fingernail processing method comprises from the pure almost completely medication method of modifying.Ideally, this finger or fingernail processing method should be modification property and medication simultaneously.But this dual purpose often is difficult to reach in single coating is handled.For example, the fingernail of modification property is handled the composition that needs non-medication usually, and as film forming polymer or pigment, they are not used in coating epidermis or proximate skin, and often these finger areas are had adverse influence (as having promoted drying property).

The fingernail of medication is handled and is helped to make nail surface smooth and softening.Exactly, this processing is nourished and has been softened epidermis and surrounding skin tissue, has reduced the fragility of fingernail itself simultaneously.This is particular importance concerning the people with dry and fragility fingernail.

In addition, the coating of finger or fingernail processing should be convenient and controlled simultaneously.User should be to for the coated treating capacity retentive control of purpose effective and attractive in appearance (being smooth and uniform coating).This easy to use and control character has also been avoided handling the dirty and messy undue coating of synthetic and has been helped to improve user to using the adaptability of this processing method.The inventor finds, method improvement of the present invention finger or fingernail handle the granting of synthetic, thereby improved convenience, aesthetic property and user and to the adaptability of this processing.

Therefore, one aspect of the present invention has provided the new and improved method of handling or preventing finger disorders, particularly fingernail and epidermis defect.

Another aspect has provided the method for moistening, smooth and softening nail surface and fingernail surrounding skin and tissue surface.

Another aspect of the present invention has provided the method for moistening, smooth and softening nail surface and fingernail surrounding skin and tissue surface, comprises adopting an improved applying device to apply finger or fingernail processing synthetic.

Summary of the invention

The present invention relates to handle or prevent the method for finger disorders, comprised the steps:

A) provide one to provide the dispensing apparatus that finger is handled synthetic, comprising:

I) shell of determining a chamber, it has one provides end and one and does the moved end, and above-mentioned granting end has a coating region and above-mentioned chamber has an inner surface, and above-mentioned coating region provides the smooth and uniform surface distributed of finger processing synthetic;

Ii) piston that is positioned at above-mentioned chamber, above-mentioned piston can move in above-mentioned chamber, above-mentioned piston has a top side in the face of the above-mentioned granting end of above-mentioned shell, and has a advancement mechanism back to above-mentioned top side, the above-mentioned top side of above-mentioned piston has formed a variable volume district of above-mentioned chamber between the above-mentioned top side of above-mentioned chamber and above-mentioned piston, wherein above-mentioned variable volume district is used to store above-mentioned fingernail and epidermis is handled synthetic; And

Iii) an actuator movably is contained on the above-mentioned shell, and movably cooperates with above-mentioned inner surface in the above-mentioned moved end of doing of above-mentioned shell, and above-mentioned actuator cooperates above-mentioned advancement mechanism, is used to make the above-mentioned granting extreme direction of above-mentioned piston towards to advance;

Wherein device has been pre-charged with finger and has handled synthetic, and finger is handled synthetic and comprised from about 1.0% to about 99% oiliness composition, and wherein synthetic comprises film forming polymer less than 1.0%; And

B) from dispensing apparatus finger being handled synthetic is issued on finger or the fingernail.

The accompanying drawing summary

Although the present technique explanation finishes with claim, pointed out and applied for claim of the present invention clearly, but phase believer in a certain religion following detailed description in conjunction with the accompanying drawings will be better understood the present invention, identical numbering is represented identical parts among the figure, wherein:

Fig. 1 is the perspective view of a preferred embodiment of dispensing apparatus of the present invention;

Fig. 2 is a vertical sectional view of not being with the dispensing apparatus shown in Figure 1 of medicated cap; And

Fig. 3 is the vertical sectional view that the dispensing apparatus shown in Figure 1 of medicated cap has been installed, and has another goods lifter embodiment.

The present invention describes the A. dispensing apparatus in detail

With reference to accompanying drawing, represent briefly that with 10 is pointed a processing dispensing apparatus, be used for providing finger and handle synthetic, as fluid, cream, semisolid, gel, ointment, liquid etc.Dispensing apparatus 10 partly comprises one, and it can be a rotating handwheel briefly with 51 actuators of representing, movably is connected on the shell 20, and shell 20 briefly is connected with 80 applicators of representing with one.Actuator can be any mechanism that is suitable for making piston-advance.For example, button or push-press type ratchet advancement mechanism are suitable succedaneum.Also for providing one to have closed end 17 and the medicated cap at beginning 18 14 with selecting for use.For example rely on the frictional fit with applicator 80, but medicated cap 14 removal ground are connected with dispensing apparatus 10.

With reference to Fig. 2, wherein can see a vertical sectional view of dispensing apparatus 10, shell 20 is hollow and elongated, and has an axis that extends along its length.Have a chamber 21 in the shell 20, and comprise one, do moved end 26 and have an inner surface 28 facing to the granting end 24 that opens wide of doing moved end 26.Preferably, inner surface 28 is cylindrical.Be used for here cylindrical be meant one elongated and have the roughly 3D shape of circular section.Preferably, inner surface 28 extends to granting end 24 from the moved end 26 of doing of shell 20.The cross sectional shape of chamber 21 may instead be different shape, as ellipse, rectangle, prolate shape, irregular shape etc.Doing moved end 26, inner surface 28 comprises a lip limit 30 and at least one braking district 32.Braking district 32 comprises that basic in inner surface 28 is partial groove, recessed district or projection.Inner surface 28 can comprise many brakings district 32, and these braking districts 32 preferably radially separate along inner surface 28.It is neighbouring with afterwards that lip limit 30 preferably is positioned at the braking district 32 that radially separates.Provide end 24 and can comprise first a undergauge district 23 that dwindles or reduce the cross section, goods are by the undergauge district when providing.Preferably, the first undergauge district 23 is a truncated cone shape.In addition, the granting end 24 of shell 20 has an outer surface 34 that comprises a rib 36.Outer surface 34 is preferably cylindrical.Shell 20 is preferentially by constituting as nylon, acrylonitrile-butadiene-styrene (ABS) (ABS), polypropylene (PP), polyethylene (PE), styrene-acrylonitrile materials such as (SAN), perhaps better by as the material of the polybutylene terephthalate (PBT) (PBT) of band ABS constitute, perhaps best, can adopt available from the BP chemical company trade mark is the modified rubber acrylonitrile copolymer of BAREX.TM.210.

A piston 40 is positioned at the chamber 21 of shell 20.This piston 40 preferably is limited to axial or moving movement in chamber 21, and does not preferably rotate with respect to inner surface 28.Piston 40 has a top side 42 and the bottom side 44 back to top side 42 in the face of shell 20 granting ends 24.When piston 40 vertically in chamber 21 when mobile, the top side 42 of piston 40 forms a variable volume district 22 in chamber 21.This variable volume district 22 is used to store will be from the goods of dispensing apparatus 10 grantings.In a preferred embodiment, the top side 42 of piston 40 is provided with a last sealing strip 43 that is sealed and matched with inner surface 28.The bottom side 44 of piston 40 also can be provided with a lower seal limit 45 that is sealed and matched with inner surface 28.Last sealing strip 43 and lower seal limit 45 radially extend outwardly from the top side 42 and the bottom side 44 of piston 40 respectively.Preferably, the goods that are stored in the variable volume district 22 of last sealing strip 43 and lower seal limit 45 preventions leak towards any other part of making moved end 26 or chamber 21 of shell 20 by piston 40.Being sealed and matched between last sealing strip 43 and lower seal limit 45 and the inner surface 28 stoped the rotation of piston 40 with frictional force.Therefore, piston 40 generally is limited to moving movement.The surface amount of contact in the change between sealing strip 43 or lower seal limit 45 and the inner surface 28 can increase or reduce these frictional force.

As shown in the figure, shell 20 is preferably and has the cylindrical of circular section roughly.Or shell 20 can have roughly oval cross section or even irregular cross section.If the chambers 21 in the shell 20 are on-circular cross-section, then the profile of chamber 21 or cross sectional shape have further prevented the rotation of piston 40, because piston 40 preferably has the profile identical with chamber 21.Piston 40 preferably is made of fluorizated high density polyethylene (HDPE) (HDPE), though also can adopt many other flexible polymers.

As shown in the figure, piston 40 also has a screw rod that stretches out back to top side 42 from piston 46.What therefore, screw rod 46 stretched to shell 20 from the bottom side 44 of piston 40 does moved end 26.Preferably screw rod 46 is made by acetal.The upper end 47 of screw rod 46 is fixedly attached to the bottom side 44 of piston 40.Therefore screw rod 46 and piston 40 are integral motion, and this motion is limited to and moves axially.The assembly that piston 40 is connected with screw rod 46 has formed a goods lifter 48, and its effect is that mobile goods are released outside the variable volume district 22 of shell 20 middle chambers 21.As shown in Figure 3, goods lifter 48 can be a single-piece, has comprised and piston 40 integrally formed screw rods 46.In preferred embodiment shown in Figure 2, piston 40 and screw rod 46 can be members separately.In order to limit the axial stroke of goods lifter 48,, can on screw rod 46, be provided with a screw rod block 49 at the other end back to screw rod 46 upper ends 47.Also can make goods lifter 48 or piston 40 in the variable volume district 22 of chamber 21, run into the path increment that limits goods lifter 48 in the end simply.Can adopt other alternative methods of restrictive axial stroke, for example, screw rod 46 can be partly threaded, and screw rod 46 or piston 40 can be done shortly or longer, piston 40 can be in the top side 42 be provided with a projection, and in the similar member axial stroke technology of restriction known various additive methods.

As shown in Figure 2, when actuator was handwheel, the actuator 50 with a screw 52 was located on the handwheel 51.Preferably, screw 52 is concentric with actuator 50.Actuator 50 shell 20 do cooperate with inner surface 28 on the moved end 26, and only be suitable for along a direction, promptly rotate with respect to shell 20 along progressive direction.Because the screw thread on the screw rod 46 cooperates with screw 52, screw rod 46 and cooperating of screw 52 are feasible when actuator 50 rotations, and piston 40 advances towards the granting end 24 of shell 20, makes goods from dispensing apparatus 10 grantings thus.

In use, handwheel 51 integral single piece that comprises actuator 50 simultaneously and hold district 54 preferably.Therefore, handwheel 51 has comprised the actuator 50 with screw 52, and have be connected with actuator 50 hold the district 54.Hold district 54 and stretch out, preferably have the surface of a trough of belt or annular knurl, so that user is easy to hold handwheel 51 from the moved end 26 of doing of shell 20.Preferably, a cavity 59 extends through holding of handwheel 51 vertically and distinguishes 54, so that the inlet that leads to screw 52 to be provided.Better, screw 52 is less than the block 49 of screw rod, and cavity 59 allows that screw rod block 49 passes through.Actuator 50 comprises a groove 56, it shell 20 do on the moved end 26 cooperate with lip limit 30 on the inner surface 28 or be hunted down, make actuator 50 to rotate but can not do axially-movable with respect to inner surface 28.This structure allows that handwheel 51 rotates and the axially-movable of prevention handwheel 51.Handwheel 51 preferably adopts the injection-molded method to form single-piece by plastics, as being the ABS of MAGNUM.TM.9015 available from the DOW chemical company trade mark, also can adopt PP homopolymer or copolymer with Acetylenogen. filler, the filling extent of filler is from about 5% to about 40% of weight.

Actuator 50 on the handwheel 51 preferably also comprises at least one elastic arm 58, radially stretches out outwardly from actuator 50, and can inward faces 28 radially tilt.The elasticity here is meant the character of elastic arm 58, and it relies on from the deflection in its home position and forces it to get back to its home position.Elastic arm 58 can find out better with reference to Fig. 4, represented the whole cross section of the dispensing apparatus 10 got along the 4-4 line of Fig. 2 among the figure.Elastic arm 58 cooperates with braking district 32 on the inner surface 28, makes actuator 50 can rotate along direction of advance but can not rotate in opposite direction.Actuator 50 preferably has at least two elastic arms 58.Better, elastic arm 58 inward faces 28 are outwards with radially at an angle, make when handwheel 51 when direction of advance is rotated, elastic arm 58 is distinguished 32 and is cooperated and be braked and distinguish 32 inside deflections with braking.When handwheel 51 when direction of advance is rotated, screw rod 46 moves towards providing end 24 with making piston 40 cooperating of screw 52.Any handwheel 51 in opposite direction rotates attempt and all is limited, and elastic arm 58 is leaned against in the braking district 32, has prevented handwheel 51 rotation in opposite direction.Because handwheel 51 only is constrained to and rotates along direction of advance, only allows that goods lifter 48 moves along a direction.Therefore, dispensing apparatus 10 has unidirectional character.

In order to provide goods from dispensing apparatus 10 with controlled manner, user rotates handwheel 51.Preferably, radially separate braking district 32, when handwheel 51 elastic arm 58 when direction of advance is rotated is distinguished 32 and cooperated and throw off with braking around inner surface 28.Elastic arm 58 is distinguished each some increment that provides piston 40 to move that cooperates of 32 with braking, therefore the increment that provides goods lifter 48 to move.The spaced radial that can change between the braking district 32 provides the piston 40 of each rotation increments axially movable many or few.For example, braking district 32 can separate equably around inner surface 28, separates brokenly, even separates discontinuously with the distance that changes.The increment of piston 40 motions has been controlled 22 product amount of providing from the variable volume district, has provided the volumetrical goods of increment, has therefore reached the increase of product dosage.The increase of this dosage helps the accurate or regular product amount of user granting, and helps avoid undue granting dirty and messy or waste.

An advantage of this structure is to produce the sound that can hear when handwheel 51 when direction of advance is rotated.Elastic arm 58 rebounds from braking district 32 and when contacting with shell 20 inner surfacies 28, has produced this click during rotating actuator 50.In addition, when rotating, direction of advance produces a tactile signal when handwheel 51.When elastic arm 58 inside deflections and be pressed on the inner surface 28 between each braking district 32 and when producing tension force, produced the sensation of being interrupted resistance to rotating.When elastic arm 58 towards when entering braking district 32 and outwards rebound, this tension force is released.For example, rotate the increase that handwheel 51 certain click numbers reach dosage, can provide accurate product dosage by regulation click number.

An applicator 80 can be connected the granting end 24 of shell 20, with variable volume district 22 fluid connections of chamber 21, makes and provides goods by applicator 80.Applicator 80 is hollow, and comprises lasso 82 and coating region 84.Applicator 80 preferably is made of plastics, as PP, PE, polyethylene terephthalate (PET), nylon or even as be the polyester of HYTREL.TM.5526 available from the DuPont company trade mark.Lasso 82 is positioned at the other end of coating region 84 and is connected with the granting end 24 of shell 20.Lasso 82 comprises an inner surface 85 with flanged lip 89.Flanged lip 89 holds the rib 36 on 24 to cooperate with granting, has formed lasso 82 and provided the interlock of holding between 24 to cooperate 79, thus applicator 80 is connected on the shell 20.The coating region 84 of applicator 80 has at least one hole 86, so that provide goods by applicator 80.Preferably, hole 86 can have the diameter from about 0.25mm (0.01 inch) to about 5mm (0.2 inch).

Refer again to Fig. 2, represented a preferred embodiment, wherein coating region 84 has a hole 86, and fiber bristle 72 stretches out by hole 86.Such fiber bristle 72 can be coning, and preferably fiber bristle 72 has thickness or the diameter from about 0.1mm (0.004 inch) to about 0.05mm (0.002 inch).These fiber bristles 72 can be made by various materials, but are preferably made by the plastics as nylon, are made by polybutylene terephthalate (PBT) (PBT) better.Change the length of fiber bristle 72 or the thickness of adjacent part, can easily change fiber bristle 72 and stretch out amount outside the coating region 84.In this preferred embodiment shown in Figure 2, in applicator 80, form an interior shoulder 88 and a platform snap close 95.Preferably platform snap close 95 86 separates vertically towards the hole, also inwardly radially separates from interior shoulder 88 in the step mode simultaneously.Four the inwardly outstanding stays of the form of platform snap close 95 for uniformly-spaced separating.Or platform snap close 95 can be any radially inside projection.One has the granting end 24 that the transition piece 90 that extends radially out limit 96 is positioned at shell 20, makes limit 96 be trapped between the granting end 24 of interior shoulder 88 and shell 20.Preferably limit 96 is separated into one to transition piece 90 and goes up transition region 97 and a following transition region 93.Transition piece 90 can be by fluoridizing HDPE or some other flexible polymer constitutes.Transition piece 90 has a passage 92, and it makes variable volume district 22 fluid connections of hole 86 and fiber bristle 72 and chamber 21.Can be positioned at passage 92 similar in appearance to 23, one second undergauge districts 25, the first undergauge district,, play the effect that reduces by the flow area of passage 92 thus to dwindle or to reduce the cross section that goods pass through when providing.Preferably, the position of transition piece 90 makes it stretch in the coating region 84 of applicator 80 by lasso 82.Or the transition piece 90 with passage 92 can stretch out and outside coating region 84 by applicator 80.In this preferred embodiment, the ring-shaped platform 94 with center drilling is fixed on the fiber bristle 72 that forms brush point 74.The last transition region 97 of transition piece 90 extends through the perforate in the ring-shaped platform 94.Ring-shaped platform 94 is trapped between the limit 96 peaceful stand lock buttons 95 of transition piece 90, makes with respect to the perforate in the coating region 84 86, and ring-shaped platform 94 has been determined fiber bristle 72 positions of brush point 74.

Refer again to Fig. 3, represented to be installed in a medicated cap of selecting for use 14 on the applicator 80 of dispensing apparatus 10, thus seal closure the perforate 86 and the coating region 84 of applicator 80.Preferably the closed end 17 of medicated cap 14 separates with applicator 80 and does not contact.As shown in Figure 1, medicated cap 14 can removal.Article one, applicator rib 16 is located on the applicator 80, and a medicated cap lock rib 19 is located at the inside of medicated cap 14.Medicated cap lock rib 19 forms can be to be interrupted or successive projection.When medicated cap 14 installed on the applicator 80, applicator rib 16 and medicated cap lock rib 19 cooperated, but medicated cap 14 removals be fixed on the applicator 80.Be positioned on the applicator 80 for medicated cap 14 is connected, the beginning 18 (Fig. 1) cooperates with applicator 80, makes applicator rib 16 cooperate with medicated cap lock rib 19.Therefore, when not using dispensing apparatus 10 user can be simply medicated cap 14 snap-in location on applicator 80, and near applicator 80 also removal medicated cap 14 easily.In the embodiment shown in fig. 3, medicated cap lock rib 19 or applicator rib 16 are out of shape a little, get back to its normal position then, keep the location to guarantee medicated cap 14, up to user in order to provide goods during removal medicated cap 14 till.The inside of medicated cap 14 also is provided with a sealing flange 15, the sealing surface 81 on its position alignment applicator 80.Sealing flange 15 on the medicated cap 14 cooperates with the sealing surface 81 of applicator 80, and being sealed and matched of medicated cap 14 and applicator 80 is provided, and makes to produce airtight between medicated cap 14 and applicator 80 when medicated cap 14 is contained on the applicator 80.Therefore, medicated cap 14 cooperates hermetically with lasso 82 on the applicator 80, has stoped any goods of preserving in the variable volume district 22 of dispensing apparatus 10 to be overflowed or product dried.Preferably, when medicated cap is positioned at the installation site, medicated cap 14 outside with applicator 80 and shell 20 between the level and smooth or concordant profile of maintenance.

Shown in Fig. 2 and 3, be easy to finish the assembling of dispensing apparatus, can come from goods lifter 48 is screwed to handwheel 51.Screw rod 46 is cooperated in some way with screw 52, and this mode makes allows that when needed the bottom side 44 of piston 40 is connected with the upper end 47 of screw rod 46.Then goods lifter 48 and handwheel 51 insert shells 20 do make groove 56 and lip limit 30 cooperate in moved end 26, connect rotationally thus and located handwheel 51, also piston 40 is positioned in the chamber 21 simultaneously, formed variable volume district 22.The time should carefully locate elastic arm 58 in assembling and suitably cooperate, with the stand under load of avoiding elastic arm 58 or skid with braking district 32.Then can be to variable volume district 22 filled articles.If desired, can put into transition piece 90 the granting end 24 of shell 20, and if desired, can be contained in brush point 74 on the transition piece 90.Can be connected to applicator 80 on the granting end 24 on the transition piece 90, catch brush point 74 during installation.But can also medicated cap 14 removals be connected on the applicator 80.

Or, also can make that doing moved end 26 faces up from being placed upside down shell 20, by doing moved end 26 piston 40 is put into the chamber 21 of shell 20 then, make bottom side 44 face up.Then handwheel 51 insert shells 20 do can be connected the upper end 47 of screw rod 46 with the bottom side 44 of piston 40 moved end 26 screw 52 of while fly 51 by cavity 59.Though can utilize dispensing apparatus 10 described herein to provide, mainly be to provide the finger that does not contain film former and/or pigment to handle synthetic as fluid, fluent material, semisolid or liquid.When adopting this dispensing apparatus 10 to provide and apply finger or fingernail processing synthetic, obtained one deck homogeneous film.

Though represented and described particular form of the present invention and embodiment, can make various modifications and not depart from the content of the present invention's explanation to this dispensing apparatus 10.For example, adopt the method beyond member is interlocked, comprise be spirally connected, glued joint, welding etc., can form the various connections between each member.The only illustrative meaning of title that in the present invention describes, adopts, and not as the title that limits.All suitable things that it is contemplated that title are included within the claims scope.In U.S. Patent number 5,851,079; Can find other suitable embodiment in 5,827,002 and 5,830,640, for integrity is all introduced here as a reference.A particularly preferred dispensing apparatus is the UC18C pen of Mitsubishi Pencil KabushkiKaisha.The more detailed description of UC18C pen can find in PCT application number PCT/JP99/01450, for integrity is introduced here as a reference.B. finger is handled synthetic

Finger of the present invention or fingernail processing synthetic can comprise, comprise or comprise basis of the present invention described herein and restriction substantially, and any batching, composition or restriction that adds or select for use described herein.

Unless otherwise provide, all percentage ratios, part and ratio are all based on the gross weight of dedicated processes synthetic of the present invention.Unless otherwise provide, therefore all these weight relevant with listing composition do not comprise the carrier or the by-product that may comprise all based on effective content in the buying material.

The word " finger or fingernail " that is used for here means fingernail and fingernail finger district on every side, comprises epidermis and surrounding skin tissue.

Be used for that the word " finger disorders " here includes, but is not limited to fragility fingernail, dry fingernail, peels off fingernail, tears fingernail, cracking skin, dry skin, peel off skin, grey pale skin, scleroma skin and fingernail agnail.

The word " safety and effective dose " that is used for here means the amount that is enough to obviously introduce the complex or the synthetic of certain effect, preferably introduce moistening and bating effect, be the minimizing of degree of drying intuitively better, the various effects of announcing have been comprised independently here, but amount is low to being enough to avoid serious adverse, promptly in the normal determination range of those of skill in the art, a rational effect and risk ratio are provided.

Here the word of Cai Yonging " processing " or " handling and/or prevention " mean the processing of fingernail in the mammal or fingernail surrounding skin defect, comprising:

(i) prevention defect promptly makes the symptom of defect not develop;

(ii) stop defect, promptly suppress the development of symptom;

(iii) alleviate defect, promptly make resolution of symptoms.

Below describe finger of the present invention in detail and handle synthetic, comprise its basis and select composition for use.

Basis oiliness composition

Basis of the present invention is the oiliness composition.Suitably the example of oiliness composition comprises fat and oil, wax, Hydrocarbon, higher fatty acids, higher alcohol, ester, essential oil and silicone oil.The example of fat and oil comprises natural fat and oil, as Oleum Glycines, rice oil (Testa oryzae oil), simmondsia oil, American Avocado Tree oil, almond oil, olive oil, cupu oil, safflower oil, Oleum Helianthi, Oleum sesami, peach kernel oil (almond oil), Oleum Ricini, Petiolus Trachycarpi oil, ermine oil, Adeps Bovis seu Bubali and leaf fat; The fixed oil that obtains by these natural fats and oily hydrogenation; And synthetic triglyceride, as trimyristin and glyceryl three (2 ethyl hexanoic acid).The example of wax comprises Brazil wax, spermaceti, Cera Flava and lanoline.The example of Hydrocarbon comprises liquid paraffin, vaseline, paraffin microwax, ceresine, squalane and pristane.The example of higher fatty acids comprises lauric acid, myristic acid, Palmic acid, stearic acid, wych-elm acid, oleic acid, linoleic acid, linolenic acid, Pilus Caprae seu Ovis fatty acid and isostearic acid.The example of higher alcohol comprises lauryl alcohol, spermol, octadecanol, oleyl alcohol, lanolin alcohol, cholesterol and 2-hexyldecanol.The example of ester comprises cetyl caprylate, glyceryl three caprylates, myristyl lactic acid, cetyl lactic acid, isopropyl butyrum nucistae, myristyl butyrum nucistae, octyl group dodecyl butyrum nucistae, isopropyl Palmic acid, isopropyl adipic acid, butyl stearate, Ceraphyl 140, cholesteryl isostearic acid and polyoxyethylene (POE) Span.The example of essential oil comprises Oleum menthae, Jasmin oil, Oleum Camphora, Japanese cypress oil, mandarin oil, rye-seed oil, Oleum Terebinthinae, Oleum Cinnamomi, oleum bergamottae, mandarin oil, calamus oil, Oleum Pini, Essential lavender oil, laurel, cloves oil, Japanese Thuja oil, Oleum Rosae Rugosae, Eucalyptus oil, Fructus Citri Limoniae oil, thyme oil, Oleum menthae, sage oil, menthol, eucalyptole, acetaminol, citral, citronellal, Borneolum Syntheticum, linalool, geraniol, Camphora, thymol, affinin, pinene, limonene and terpene blend.The example of silicone oil comprises dimethyl polysiloxane.These oiliness compositions can use separately or two or several being used in combination.In the present invention, preferentially adopt the glyceryl myristin, glyceryl three (2 ethyl hexanoic acid), lanoline, liquid paraffin, vaseline, the paraffin microwax, squalane, lauric acid, myristic acid, Palmic acid, linoleic acid, linolenic acid, isostearic acid, spermol, octadecanol, oleyl alcohol, cholesterol, the cetyl caprylate, glyceryl three caprylates, the isopropyl myristin, octyl group dodecyl myristin, the cholesteryl isostearic acid, the POE Span, Oleum menthae, mandarin oil, Oleum Cinnamomi, Oleum Rosae Rugosae, menthol, eucalyptole, acetaminol, citral, citronellal, geranial, pinene, limonene and dimethyl polysiloxane.

The oiliness composition preferentially comprised finger handle synthetic from about 1% to about 99%, better from about 50% to about 95%, best from about 75% to about 90%.Substantially do not contain film former

Finger of the present invention is handled synthetic and preferably is substantially free of film former.In general, used here word " is substantially free of " magnitude that means film former about 1% or still less, and better about 0.5% or still less, preferably about 0.1% or still less, even more preferably 0% or be not more than 0.05%.

Typical film former includes, but is not limited to: acrylamide/sodium acrylate copolymer; The ammonium acrylate copolymer; Peruvian balsam; Polyurethane and urethane derivative are as aliphatic polyester polyurethane; Cellulose gum; Cellulosic polymer (as the cellulose esters of nitrocellulose and so on), ethylene maleic anhydride copolymers; Hydroxyethyl-cellulose; Hydroxypropyl cellulose; Polyacrylamide; Polyethylene; Polyvinyl alcohol; PVM/MA copolymer (polyvinyl methyl ethermaleic anhydride maleic anhydride); PVP (polyvinylpyrrolidone); Maleic anhydride copolymers is as the PA-18 available from Gulf scientific ﹠ technical corporation; PVP/ hexadecene copolymer is as the Ganex V-216 available from GAF company; Acrylic acrylic salt copolymer; Or the like.The additional examples of film former can be at U.S. Patent number 5,639, finds in 447, for integrity is introduced here as a reference.

Be not subjected to theoretic restriction, can think that film former has adverse effect to epidermis and fingernail surrounding skin tissue.The inventor finds that film forming polymer makes skin feel drying and itch.The present invention has directly improved the sensation (promptly softening and moistening skin) of skin and has improved the whole outward appearance of skin (skin color that has been even and reduced " greyish white " outward appearance of skin).Substantially do not contain pigment

Finger of the present invention is handled synthetic and is not preferably contained pigment basically.In general, used here word " is substantially free of " magnitude that means this coloring components or pigment about 0.1% or still less, and better about 0.075% or still less, best 0% or be not more than about 0.05%.

Typical pigment includes, but is not limited to organic and inorganic pigment and dyestuff.Organic pigment generally is various aromatic series types, comprises azo, indigoid, tritan., anthraquinone and xanthine dyestuff, is designed to D﹠amp; C and FD﹠amp; C blueness, brown, green, crocus, redness, yellow etc.Organic pigment generally is made up of the insoluble slaine of qualified color additives, is called the color lake.Inorganic pigment comprises ferrum oxide, ultramarine and chromium or chromic oxide gel pigment, with and composition thereof.

Be not subjected to theoretic restriction, can think that pigment has adverse effect to the health of epidermis and fingernail surrounding skin tissue, as user is felt.User is avoided usually to these skin area coating pigments, with health and the youth outward appearance that keeps these zones.

Select composition for use

Finger of the present invention is handled synthetic can comprise additional cosmetics, and they are generally used in this prescription, for example antiseptic; As biotin, vitamin B ₅And derivant (as pantothenol), vitamin B ₃And derivant (as nicotiamide).The skin care actives of vitamin E and derivant thereof (as the tocopherol nicotinate), phospholipid, alpha-hydroxy acid (as glycol acid, lactic acid), beta hydroxy acid (as salicylic acid), vitamin A and derivant (as tretinoin and retinoic acid ester), vitamin C and vitamin D; Antibacterial; Perfume; The resistance membrane; Thickening agent; Surfactant; Emulsifying agent; Plasticizer; Wetting agent and/or wetting agent; Fat outside the basis of being announced and wax; Perhaps as other conventional ingredients of the cosmetics of ethanol, polyhydric alcohol or water; Membrane stabilizer; Electrolyte; Organic solvent or silicon derivative.U.S. Patent number 5 at the Blank of on July 7th, 1998 issue etc., 776, among the PCT application number WO 97/39733 of the Oblong of on October 30th, 918 and 1997 issue etc., describe these and other suitable compositions of selecting for use in detail, here for integrity is introduced as a reference.

In the time of in water-soluble substance being added to finger processing synthetic of the present invention, synthetic can be the form of wet oil or oil-containing water Emulsion.Preferably, Emulsion is the wet oil solvent.Handle and/or prevent the method for finger disorders

The method of processing and prevention finger disorders comprises that the present invention of safety and effective dose is pointed the processing synthetic to be coated onto on the finger partly, particularly on the fingernail.According to desirable degree of treatment, as progress and other symptom variation speed according to finger disorders, the synthetic amount of coating, coating number of times and service time are with great changes have taken place.

In a preferred embodiment, synthetic is coated on the finger chronically, particularly is coated on the fingernail." long-term local coating " means and gone up for a long time by treatment person in the life-span, the local coating synthetic preferentially is at least about the time in a week, is more preferably at least about one month even better at least about three months even better at least about six months and better at least about 1 year continuously.Although can obtain effect afterwards in each maximum operating period (as 5 years, 10 years or 20 years), preferably long-term coating is extended to the whole treatment person's of being subjected to life-span.Typical coating be in this extended period every day magnitude approximately once, but the speed of coating can once change to about three times or more of every day approximately from jede Woche.

Can adopt the far-ranging quantity of synthetic of the present invention that the outward appearance and/or the sensory effect of finger and/or fingernail are provided.Usually the synthetic quantity of the present invention of each coating is with (synthetic of mg)/(cm ²Skin and fingernail) calculate, from about 0.1mg/cm ²To about 100mg/cm ²Useful especially coating amount is about 10mg/cm ²

Preferably apply with the oiliness synthetic, perhaps the synthetic of oil-containing water or wet oil Emulsion and so on form is realized method of the present invention, and synthetic is used to stay on the skin to obtain some attractive in appearance, prevention and treatment or other effects (synthetic of promptly a kind of " staying ").After synthetic is coated to skin, preferentially stay on the skin at least about 15 fens clock times, better at least 30 minutes approximately, even better at least 1 hour approximately, best several hrs at least was as up to 12 hours.

For example

The using method that comprises dispensing apparatus of the present invention and finger processing synthetic has been described in following indefiniteness example.Those skilled in the art can carry out other modification and without departing from the spirit and scope of the present invention.Adopt dispensing apparatus of the present invention and finger to handle the adaptability of the synthetic wettability of having come method improvement for example and user and finger processing synthetic.

Can adopt conventional prescription and hybrid technology to prepare the synthetic that all are given an example.The one-tenth component of listing is weight percentage, and comprises small quantity of material, as diluent, filler etc.So listed prescription has comprised the composition of listing and any small quantity of material relevant with these compositions.

Example I

A kind of method of handling finger disorders, the finger that has adopted dispensing apparatus to apply following oiliness synthetic form is handled synthetic.

Oleum Helianthi 25%

Safflower oil 25%

Oleum Glycines 25%

Olive oil 20%

Vitamin E tocopherol 2%

(antiseptic etc.) 3% on a small quantity

Above composition is added in the rustless steel container, adopt conventional hybrid technology thoroughly to mix.Then the finger handling oil is packed in the dispensing apparatus, and adopt dispensing apparatus to be coated on the finger, particularly be coated on fingernail and the epidermis.

Example II

A kind of method of handling finger disorders, the finger that has adopted dispensing apparatus to apply following wet oil Emulsion form is handled synthetic.

Oleum Helianthi 23%

Safflower oil 23%

Oleum Glycines 25%

The two methyl of cetyl are multi-hydroxy silicone oil (emulsifying agent) 0.5% altogether

Water 10%

Glycerol 10%

Niacinamide usp 2%

(antiseptic etc.) 4.5% on a small quantity

In the rustless steel container of thermal source is housed, miscella (Oleum Helianthi, safflower oil and Oleum Glycines) and emulsifying agent, and be accompanied by and be stirred and heated to 150F.In an independent rustless steel container, be accompanied by to stir and add water, glycerol, niacinamide usp and antiseptic, and be mixed into evenly.Be mixed together oil and aqueous mixtures then, be accompanied by the stirring cool to room temperature.Then finger is handled pack into dispensing apparatus and adopting on the dispensing apparatus coating finger of Emulsion, particularly be coated on fingernail and the epidermis.

Claims

1. a method of providing and apply fingernail and epidermis processing synthetic is used for handling or the prevention finger disorders, and method comprises the steps:

2. a method of providing and apply fingernail and epidermis processing synthetic is used for handling or the prevention finger disorders, and method comprises the steps:

Wherein device has been pre-charged with finger and has handled synthetic, and finger is handled synthetic and comprised from about 1.0% to about 99% oiliness composition, and wherein synthetic comprises color element less than 0.1%; And

3. a method of providing and apply fingernail and epidermis processing synthetic is used for handling or the prevention finger disorders, and method comprises the steps:

Wherein device has been pre-charged with finger and has handled synthetic, and finger is handled synthetic and comprised from about 1.0% to about 99% oiliness composition, and wherein synthetic comprises less than 1.0% film forming polymer with less than 0.1% color element; And

4. one kind according to arbitrary method in the above claim, and wherein inner surface also comprises at least one braking district.

5. one kind according to arbitrary method in the above claim, and wherein actuator also comprises the elastic arm that at least one stretches out and cooperates with the braking district outwardly, makes that actuator can be along direction of advance but can not move in opposite directions.

6. one kind according to arbitrary method in the above claim, wherein piston has a top side in the face of shell granting end, and has a screw rod that stretches out back to the top side from piston, wherein actuator is one and has and hold the district and the handwheel of actuator, actuator cooperates with above-mentioned inner surface on the moved end above-mentioned work of shell, and be suitable for only rotating with respect to shell along a direction, actuator has screw, screw rod cooperates with screw, make that piston advances towards providing end when actuator is rotated, make the said products granting thus.

7. one kind according to arbitrary method in the above claim, and wherein actuator also comprises the lip limit, makes above-mentioned actuator to rotate with respect to inner surface but can not do axially-movable.

8. one kind according to arbitrary method in the above claim, and wherein actuator is by thermoplastic integrally formed single whole.

9. one kind according to arbitrary method in the above claim, wherein dispensing apparatus also comprises an applicator, it is connected to the granting end of shell, with the above-mentioned variable volume district fluid connection of above-mentioned chamber, wherein handles synthetic by above-mentioned applicator granting finger.

10. one kind according to arbitrary method in the above claim, and wherein finger is handled synthetic and also comprised a kind of skin care actives.