CN1364608A - Powder for curing gout - Google Patents

Abstract

Gout treating granule as a kinds of Chinese medicine is prepared with scorpion, Resina Draconis, peach kernel, safflower, Radix Clematidis and other nine Chinese medicinal materials and through grinding into fine powder and bagging. It is taken after being mixed with boiling water. The said medicine has high curative effect, no toxic side effect and low recurrence rate.

Description

Powder for curing gout

The present invention relates to a kind of Chinese patent medicine.

Gout is a kind of commonly encountered diseases.General onset is rapid, usually in prominent sense joint severe pain at night, and with General Symptomies such as heatings, redness and swelling of joints, burning pain, activity is restricted etc.Common site is halluces, metatarsophalangeal joints, ankle joint, elbow joint, and the joint engenders that deformity is stiff, and follows other disease.From traditional Chinese medical science angle, gout is the common disease of a kind of rheumatism, results from deficiency of both QI and blood, interspaces of skin and muscles being loose, and wet three gas of wind and cold occupy due to the meridians joint.Modern medicine thinks that gout is because purine (molecular formula C ₆H ₄N ₄) a kind of disease that metabolism disorder causes, purine metabolism thing uric acid concentration increases in the blood, and urate is separated out crystallization deposition and is caused damage at some position of health.In the last few years, the gout sickness rate had the trend that increases, particularly in the middle of middle-aged and elderly people and male.To this sick Therapeutic Method, the not fast thujol of doctor trained in Western medicine injection, slight injection hormone analgesic.The traditional Chinese medical science is supported face, expelling wind and removing dampness based on QI invigorating.But, no matter be western medical treatment at present, or Chinese traditional treatment, relapse rate is very high, outbreak repeatedly soon after the treatment.

The present invention is intended to release a kind of new Chinese patent medicine for the treatment of gout.

The present invention selects Chinese crude drug Scorpio, Sanguis Draxonis, Semen Persicae, Flos Carthami, Radix Clematidis, Semen Phaseoli, Radix Paeoniae Rubra, Radix Stephaniae Tetrandrae, Rhizoma Smilacis Glabrae, Semen Coicis, Radix Angelicae Sinensis for use, must change, Retinervus Luffae Fructus, Folium et Ramulus Clerodendri Trichotomi compositing formula, adds two and makes powder, packs with bag to get product.Boiled water is taken after mixing it with water during medication.

The powder for curing gout that the present invention releases, through clinical 102 routine URs, cure rate reaches 67.6%, obvious effective rate 20.6%, effective percentage 9.8%, inefficiency 2.0% is visited healing person, and relapse rate is that relapse rate is 1.4% after 0,1 year after half a year.Now (containing in December, 1999) clinical effectiveness before in the December, 1999 is described below.

1, clinical data

1.1 case is selected according to the relevant diagnostic criteria in " tcm clinical practice disease diagnosis criterion of therapeutical effect ".

1.2 physical data is included clinic case 102 examples in, male 77 examples, women 25 examples; Age: 23-30 year 4 examples, 31-40 year 19 examples, 41-50 year 32 examples, 51-60 year 34 examples, person's 13 examples more than 61 years old; Occupation: peasant's 27 examples, workman's 32 examples, office worker's 43 examples; The course of disease: 1-5 69 examples, person's 33 examples more than 5 years.

2, Therapeutic Method

Oral Chinese patent medicine, every days 30, gram divided 3 times, and boiled water is taken after mixing it with water.Take 4-5 week continuously according to the state of an illness, no longer take the medicine of other any treatment gout in 2 months.Note diet three peppery and plucks simultaneously, wine for giving off smoking avoids exertion.Check blood uric acid concentration and hepatic and renal function before the treatment, row check again in full 2 months, statistics curative effect.To the clinical cure person respectively at visiting half a year, 1 year, 2 years or letter is transferred the recurrence situation.

3, therapeutic outcome

3.1 criterion of therapeutical effect is drafted according to new drug (Chinese medicine) treatment joint disease clinical research guideline.Clinical cure: joint motion and profile thereof recover normal, and the blood uric acid concentration is normal; Produce effects: the basic restore funcitons of joint motion, the blood uric acid concentration obviously descends; Effectively: joint movement function takes a turn for the better to some extent, and the blood uric acid concentration descends to some extent; Invalid: after treatment, symptom does not take a turn for the better.

3.2 therapeutic outcome: see Table 1.

Table 1 powder for curing gout treatment gout curative effect statistics

Curative effect	Case load	Ratio (%)	Total effective rate (%)
				Clinical cure	????69	????67.6	????98.0
Produce effects	????21	????20.6
			Effectively	????10	????9.8
Invalid	????2	????2.0				????2.0
			Add up to	????102	????100		????100

3.3 the clinical cure person visits the result: see Table 2.

Table 2 half a year, 1 year recurrence situation

Case load	Time and recurrence situation
					Half a year		1 year
	The recurrent cases number	Relapse rate (%)	The recurrent cases number	Relapse rate (%)
					????69	????0	????0	????1	????1.4

3.4 this group of toxic and side effects is observed case medication before and after look liver, renal function no change, and no overt toxicity effect is described.Ill symptomses such as the patient takes medicine does not afterwards have diarrhoea, feel sick, explanation has no side effect.

4, clinical application effect summary

This medicine treatment gout, clinical effectiveness is good; Though the anti-recurrence effect observation time is not long, lack 2 years healing persons and visit data (because of some case was wherein cured back less than 2 years, the inconvenience statistics), but from half a year and 1 year the clinical cure person visit situation, this medical instrument has anti-recurrence effect preferably, can reduce the generation of complication.This medicine does not have the overt toxicity effect, has no side effect.

5, model case

Guo Lingzhi, the man, 48 years old, reformed town heated water stream people from village the Shimen County, Hunan Province.Nineteen ninety begins the causus pain in big toe joint, and day light night is heavy, can not land wrist, elbow joint pain.Through the western medicines in treatment commentaries on classics of not getting better.In June, 1999 the arthralgia grand mal, the purine of moaning.Can not land, to the county hospital inspection, the blood uric acid concentration increases, and is diagnosed as gout.Rise and take this medicine in July, 1999, obeys week posterior joint pain not, can walk.It is normal that posterior joint activity of four weeks and the profile thereof of taking medicine recovered, and the blood uric acid concentration is normal.Cure.

Yang Gongnian, the man, 45 years old, the town was reformed from Yang Shu village people in the Shimen County, Hunan Province.Began to occur the causus pain in big toe joint in 1996, can not land, with cold and heat, headache, cardiopalmus, outbreak repeatedly.The causus pain in October, 1999 big toe joint, grand mal can not land.Fear of cold, headache, cardiopalmus, the blood uric acid concentration increases, and is diagnosed as gout.Through gout electuary treatment, the week joint pain not of taking medicine can be walked.It is normal that posterior joint activity of four weeks and the profile thereof of taking medicine recovered, and the blood uric acid concentration is normal.Cure.

Lei Gongzheng, man, 74 years old, the office clerks of changde, hunan province municipal Party committee.Began the causus pain in sufficient big toe joint in 1991, day light night is heavy, can not land wrist joint pain.Through the western medicines in treatment poor effect.In March, 1999, characteristic of disease increased the weight of, and checked through Changde City, and the blood uric acid concentration increases, and is diagnosed as gout.On March 5th, 1999 rose and takes powder for curing gout, and pain relief after the week can be walked.It is normal that oral four weeks posterior joint activity and profile thereof are recovered, and the blood uric acid concentration is normal.Cure.

Qin Bo, woman, 24 years old, changde, hunan province people from city.Began the causus pain in sufficient big toe joint in 1998, can not land, nervous, cardiopalmus.Through examination in hospital is gout.Take powder for curing gout in January, 1998, pain relief after the week, joint motion can be walked freely.It is normal that oral five weeks posterior joint activity and profile thereof are recovered, and the blood uric acid concentration is normal.Cure.

Liu Shengbin, man, 49 years old, changde, hunan province people from city.Nineteen ninety-five begins the causus pain in sufficient big toe joint, can not land, repeatedly outbreak.Check that to my institute the blood uric acid concentration increases in January, 1998.Oral powder for curing gout pain relief after one week, symptom is clearly better after two weeks.The complete obiteration of four stars after date symptom, joint motion and profile thereof recover normal, and the blood uric acid concentration is normal.Cure.

Wu Taoxian, woman, 24 years old, changde, hunan province people from city.The causus pain in beginning big toe joint in 1996 can not be walked, repeatedly outbreak.In February, 1998, the blood uric acid concentration increased, and is diagnosed as gout to the county hospital inspection.In March, 1998 oral powder for curing gout, two week sx, it is normal that five-pointed star after date joint motion and profile thereof are recovered.The blood uric acid concentration is normal.Cure.

Tall and erect merchant's celebrating, man, 49 years old, mill people from city, Shimen County, Hunan Province.The causus pain in beginning big toe joint in 1994 can not be walked, repeatedly outbreak.Be diagnosed as gout to examination in hospital in January, 1999.Oral immediately powder for curing gout, sx after the week.Two week the posterior joint redness disappear.The basic restore funcitons of five-pointed star after date joint motion, the blood uric acid concentration obviously descends.Produce effects.

Below, introduce most preferred embodiment of the present invention.

Prescription: Scorpio 10-15 gram, Sanguis Draxonis 10-15 gram, Semen Persicae 10-15 gram, Flos Carthami 5-10 gram, Radix Clematidis 5-10 gram, Semen Phaseoli 10-15 gram, Radix Paeoniae Rubra 10-15 gram, Radix Stephaniae Tetrandrae 10-15 gram, Rhizoma Smilacis Glabrae 10-15 gram, Semen Coicis 10-15 gram, Radix Angelicae Sinensis 10-15 gram, must change the 5-10 gram, Retinervus Luffae Fructus 10-15 gram, Folium et Ramulus Clerodendri Trichotomi 5-10 gram.

Manufacture method: with its pulverize, make powder, be packaged into bag.Every bag 10 gram.

Claims (2)

1, powder for curing gout is characterized in that the gram with Scorpio 10-15, Sanguis Draxonis 10-15 gram, Semen Persicae 10-15 gram, Flos Carthami 5-10 gram, Radix Clematidis 5-10 gram, Semen Phaseoli 10-15 gram, Radix Paeoniae Rubra 10-15 gram, Radix Stephaniae Tetrandrae 10-15 gram, Rhizoma Smilacis Glabrae 10-15 gram, Semen Coicis 10-15 gram, Radix Angelicae Sinensis 10-15 gram, must change the 5-10 gram, Retinervus Luffae Fructus 10-15 gram, Folium et Ramulus Clerodendri Trichotomi 5-10 restrains pulverize, make powder, be packaged into bag.

2, the powder for curing gout of narrating according to claim 1 is characterized in that every bag of intermediate package 10 gram powder.