CN1357246A - Levo-carnitine feed additive and its prepn - Google Patents
Levo-carnitine feed additive and its prepn Download PDFInfo
- Publication number
- CN1357246A CN1357246A CN00123372A CN00123372A CN1357246A CN 1357246 A CN1357246 A CN 1357246A CN 00123372 A CN00123372 A CN 00123372A CN 00123372 A CN00123372 A CN 00123372A CN 1357246 A CN1357246 A CN 1357246A
- Authority
- CN
- China
- Prior art keywords
- levo
- carnitine
- organic carrier
- feed additive
- grease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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- Fodder In General (AREA)
Abstract
The levo-carnitine feed additive of the present invention consists of levo-carnitine as main component 10-40 wt%, organic carrier 50-80 wt%, wate 4-20 wt% and preservative 0.4-1.2 wt%. The said organic carrier is powder produced with stalk, hull and core of grain crop. The preparation process includes mixing levo-carnitine, preservative and water to oily mixture, spraying the mixture to organic carrier, remixing and packing. The additive is rich in nutrients and is easy to absorb by animal.
Description
The present invention relates to feed addictive that contains active l-cn and preparation method thereof.
L-cn has another name called levocarnitine, English name: the Levocarnitine structural formula is as follows:
Physicochemical property: outward appearance: white crystalline powder, very easily moisture absorption has little fishy smell.
Hygroscopicity: under 66% relative humidity, 24 hours absorption moisture content 67.7%
Optical activity: [α]
D 25-29～-31
PH value: 6-7
Chemical property: 1. heating easily is dehydrated into crotonbetaine under acid condition
2. (180 ℃) decomposition is at high temperature emitted trimethylamine and is formed lactone
3. forming the salt hygroscopicity with acid just descends significantly.
4. very easily water-soluble, be dissolved in hot ethanol and methyl alcohol, be insoluble in acetone, chloroform, the ether.
L-cn is the nutriment of ubiquitous a kind of biostearin in animals and plants and the microorganism, and its major function is as carrier, and LCFA is delivered to outside mitochondrial membrane in the film, promotes the beta oxidation of aliphatic acid, changes fatty acid metabolism into energy.This plays very important effect to animal metabolism.In vivo, l-cn mainly is present in liver and the kidney, and is synthetic through enzymatic, indispensable under vitamin C, ferrous ion, nicotinic acid and vitamin B6 participate in by 1 lysine and 3 methionine.But the feed based on vegetable protein often exists methionine deficiency, lysine to lack and the not enough problem of vitamin C interpolation, cause using in the animal tissue of this class feed lacking l-cn, and then cause situations such as slow, the disease-resistant anti-stress ability of growth of animal weakens to occur.Other has reported in literature, and l-cn becomes positive correlation to survival rate, sperm motility, the sperm concentration of sperm in the arrenotoky physiological action.In a word, development along with the intensive farm industry, be the needs that satisfy the livestock and poultry high reproductive rate and grow fast, l-cn content in the natural feed can not satisfy the needs of growth of animal far away, therefore replenish l-cn, develop the feed addictive that contains l-cn to animal, very important to development livestock rearing industry.
At present, the existing document announcement that l-cn is applied to additive, be carrier as just having introduced with silica in the Switzerland LONZA company industry data (nineteen ninety-five), l-cn is added suitable quantity of water be made into grease, form mobile powder with silica absorption then, usually carnitine content about 50%, other has 35% silica that can't assimilate for animal.With this feed addictive nutrition purposes, especially for feeding animals, not only nutrition is relatively dull, and the effective rate of utilization of additive is low, and wherein 35% is the nonabsorbable mineral matter silica of animal, this to the user still be producer all be a kind of waste.
The purpose of this invention is to provide a kind of with the edible carrier be adsorbent contain feed addictive of l-cn and preparation method thereof, this preparation of product is easy, cheap, be rich in nutrition, helps animal and absorbs.
Feed addictive of the present invention also contains organic carrier, moisture, anticorrisive agent based on the active component l-cn, its components based on weight percentage:
L-cn 10-40%
Organic carrier 50-85%
Moisture 4-20%
Anticorrisive agent 0.1-1%
Organic carrier can be pulverized the powder that forms with stem, shell, the core of cereal crops, as maize cob meal, soya bean folder powder, straw powder, bran powder, and can single use or several mixing.
Prepare the method for levo-carnitine feed additive, it is characterized in that: earlier l-cn, anticorrisive agent are added the water stirring and be made into grease, grease is sprayed on the organic carrier of high degree of agitation with spray gun then, after spray Bi Jixu stirs, the discharging packing.
Adopt the feed addictive of the present invention's preparation, except that offering growth of animal, growing the necessary l-cn, its carrier also can be brought into play the feed effect, for animal provides abundant nutrition.These carriers are of many uses in livestock rearing in addition, have positive role to enlarging the scope of application of promoting the l-cn additive.This product preparation method is simple, aboundresources, cost are low, and the opportunity of collaborative development is provided for producer, the user of businessman.
Usage: theoretically, the value range of l-cn magnitude of recruitment should be to contain l-cn 0.4-1.2% in vivo.The user can extrapolate the ratio of this additive and feed according to the different growing stages of various animals.
Embodiment: example 1
With l-cn crystalline powder 50g, add entry 7.5ml, amounting to water content is 15%, stir into grease, put into spray gun and spray into 100g just at the dry corncob powder of 200 orders of high degree of agitation, spray is complete stirred 20 minutes again, and it is 31.75% that chemical examination contains l-cn.
Example 2 adds entry 7.5ml with l-cn crystalline powder 50g, stirs into grease, sprays into 200g just in the dry corncob powder of 150 purposes of high degree of agitation, and spray is finished and stirred 20 minutes again, and it is 19.4% that chemical examination contains l-cn.
The concentrated grease 50g of example 3 before with the l-cn crystallization measures its content and is not less than 95% back and adds, and the spray inspection of directly packing into is sprayed onto in the 200 order maize cob meals of high degree of agitation of 300g drying, stirs 20 minutes again, and it is 14.28% that chemical examination contains l-cn.
Example 4 adds l-cn crystalline powder 50g in the solution of 0.1g Sodium Benzoate and 7.5ml water, heating stirs into grease, spray into 100g just in the dry corn flour of 100 purposes of high degree of agitation, spray is finished and was stirred 20 minutes again, and chemical examination l-cn content is 31.73%.
Claims (2)
1, a kind of levo-carnitine feed additive is characterized in that: based on the active component l-cn, also contain organic carrier, moisture, anticorrisive agent, its components based on weight percentage:
L-cn 10-40%
Organic carrier 50-85%
Moisture 4-20%
Anticorrisive agent 0.1-1%
Organic carrier can be pulverized powder, single use or several mixing that forms with stem, shell, the core of cereal crops.
2, a kind of method for preparing levo-carnitine feed additive is characterized in that: earlier l-cn, anticorrisive agent are added water and stir and be made into grease, then with spray gun with grease be sprayed at having of high degree of agitation airborne on, after spray Bi Jixu stirs, the discharging packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001233726A CN1203776C (en) | 2000-12-07 | 2000-12-07 | Levo-carnitine feed additive and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001233726A CN1203776C (en) | 2000-12-07 | 2000-12-07 | Levo-carnitine feed additive and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1357246A true CN1357246A (en) | 2002-07-10 |
| CN1203776C CN1203776C (en) | 2005-06-01 |
Family
ID=4589821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001233726A Expired - Lifetime CN1203776C (en) | 2000-12-07 | 2000-12-07 | Levo-carnitine feed additive and its prepn |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1203776C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100518537C (en) * | 2006-01-13 | 2009-07-29 | 天津天隆农业科技有限公司 | Aquatic feedstuff containing octocosoic alcohol and L-carnitine and production method thereof |
| CN106922970A (en) * | 2017-03-10 | 2017-07-07 | 大连理工大学 | Specificity with corncob as carrier is shelled shell egg antibody preparation and preparation method thereof |
| CN106942469A (en) * | 2017-03-10 | 2017-07-14 | 大连理工大学 | Special yolk humoral antibody preparation by carrier of corncob and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5149172B2 (en) * | 2005-07-05 | 2013-02-20 | ロンザ アーゲー | Spray drying method for producing dry carnitine powder or granules |
-
2000
- 2000-12-07 CN CNB001233726A patent/CN1203776C/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100518537C (en) * | 2006-01-13 | 2009-07-29 | 天津天隆农业科技有限公司 | Aquatic feedstuff containing octocosoic alcohol and L-carnitine and production method thereof |
| CN106922970A (en) * | 2017-03-10 | 2017-07-07 | 大连理工大学 | Specificity with corncob as carrier is shelled shell egg antibody preparation and preparation method thereof |
| CN106942469A (en) * | 2017-03-10 | 2017-07-14 | 大连理工大学 | Special yolk humoral antibody preparation by carrier of corncob and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1203776C (en) | 2005-06-01 |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: NORTHEAST PHARMACEUTICAL GROUP CO., LTD. Free format text: FORMER OWNER: NORTHEAST PHARMACEUTICAL PLANT Effective date: 20100419 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 110026 NO.37, ZHONGGONG NORTH STREET,TIEXI DISTRICT, SHENYANG CITY, LIAONING PROVINCE TO: 110026 NO.37,ZHONGGONG NORTH STREET, TIEXI DISTRICT, SHENYANG CITY |
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| TR01 | Transfer of patent right |
Effective date of registration: 20100419 Address after: 110026, No. 37, North Street, heavy industry, Tiexi District, Shenyang Patentee after: Northeast Pharmaceutical Group Co., Ltd. Address before: 110026, No. 37, North Street, heavy industry, Tiexi District, Liaoning, Shenyang Patentee before: Dongbei Pharmaceutical Factory |
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| CX01 | Expiry of patent term |
Granted publication date: 20050601 |
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| CX01 | Expiry of patent term |